Citation Impact
Citing Papers
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
GPCR Engineering Yields High-Resolution Structural Insights into β 2 -Adrenergic Receptor Function
2007 StandoutScienceNobel
A fluorescent probe designed for studying protein conformational change
2005 StandoutNobel
A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling
2007 StandoutNobel
The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist
2008 StandoutScience
Pharmacological Onomastics: What's in a name?
2007
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the µ-opioid-receptor gene
1996 Nature
G-protein-coupled Receptor Kinase Specificity for β-Arrestin Recruitment to the β2-Adrenergic Receptor Revealed by Fluorescence Resonance Energy Transfer
2006 StandoutNobel
Monofunctionalized Pillar[5]arene as a Host for Alkanediamines
2011 StandoutNobel
Prolonged Kappa Opioid Receptor Phosphorylation Mediated by G-protein Receptor Kinase Underlies Sustained Analgesic Tolerance
2004 StandoutNobel
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
2007 StandoutNatureNobel
Structure and Conformational Changes in the C-terminal Domain of the β2-Adrenoceptor
2007 StandoutNobel
Probing the β2 Adrenoceptor Binding Site with Catechol Reveals Differences in Binding and Activation by Agonists and Partial Agonists
2005 StandoutNobel
Red Fluorescent Turn‐On Ligands for Imaging and Quantifying G Protein‐Coupled Receptors in Living Cells
2014
Agonist Binding: A Multistep Process
2004 StandoutNobel
Synthesis and biological evaluation of a triazole-based library of pyrido[2,3-d]pyrimidines as FGFR3 tyrosine kinase inhibitors
2010
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
2010 StandoutNatureNobel
Kinetic Analysis of G Protein–Coupled Receptor Signaling Using Fluorescence Resonance Energy Transfer in Living Cells
2007
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
2012 StandoutNatureNobel
Disruption of the kappa -opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective kappa -agonist U-50,488H and attenuates morphine withdrawal
1998
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
Conformational complexity of G-protein-coupled receptors
2007 StandoutNobel
BODIPY–Thiophene Copolymers as p‐Channel Semiconductors for Organic Thin‐Film Transistors
2013 StandoutNobel
Phosphoramidites: Privileged Ligands in Asymmetric Catalysis
2010 StandoutNobel
Copper(I)‐Catalyzed Cycloaddition of Organic Azides and 1‐Iodoalkynes
2009 StandoutNobel
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
Cu-free click cycloaddition reactions in chemical biology
2010 StandoutNobel
The genomic clone G-21 which resembles a β-adrenergic receptor sequence encodes the 5-HT1A receptor
1988 StandoutNatureNobel
Sequential Binding of Agonists to the β2 Adrenoceptor
2003 StandoutNobel
β1-Adrenergic Receptor Association with PSD-95
2000 StandoutNobel
Collateral efficacy in drug discovery: taking advantage of the good (allosteric) nature of 7TM receptors
2007
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
2015 StandoutNobel
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
2018 StandoutNobel
Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2
1999 StandoutScienceNobel
Distinct conformational changes in β-arrestin report biased agonism at seven-transmembrane receptors
2008 StandoutNobel
Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB 1 Receptor Knockout Mice
1999 StandoutScience
Plasmon-Waveguide Resonance Studies of Ligand Binding to the Human β2-Adrenergic Receptor
2004 StandoutNobel
Cooperative capture synthesis: yet another playground for copper-free click chemistry
2016 StandoutNobel
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor
2012 StandoutNobel
Nanowire Nanosensors for Highly Sensitive and Selective Detection of Biological and Chemical Species
2001 StandoutScience
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
2000 StandoutNatureNobel
Characterization of the receptor for heat-stable enterotoxin from Escherichia coli in rat intestine.
1986 StandoutNobel
β-arrestin- but not G protein-mediated signaling by the “decoy” receptor CXCR7
2009 StandoutNobel
Calmodulin pharmacology
1981
Trapping of a Spatial Transient State During the Framework Transformation of a Porous Coordination Polymer
2014 StandoutNobel
BODIPY Dyes and Their Derivatives: Syntheses and Spectroscopic Properties
2007 Standout
Drug Abuse: Hedonic Homeostatic Dysregulation
1997 StandoutScience
Use of Cholate/Sodium Chloride for Solubilisation of Brain D2 Dopamine Receptors
1983
Regulation of microtubule cold stability by calmodulin-dependent and -independent phosphorylation.
1983 StandoutNobel
Three-dimensional structure of calmodulin
1985 StandoutNature
Affinity chromatography of the muscarinic acetylcholine receptor.
1983
A Photoactivatable Push−Pull Fluorophore for Single-Molecule Imaging in Live Cells
2008 StandoutNobel
A rapid filtration assay for soluble receptors using polyethylenimine-treated filters
1983
Update 1 of: Computational Modeling Approaches to Structure–Function Analysis of G Protein-Coupled Receptors
2011
Co-purification of an atrial natriuretic factor receptor and particulate guanylate cyclase from rat lung.
1986 StandoutNobel
Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands
2009 StandoutNobel
The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex
2009 StandoutNobel
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Calmodulin
1982
Photoaffinity Labelling and Solubilization of the Central 5-HT1AReceptor Binding Site
1987
Recent Trends in Photoaffinity Labeling
1995
Real-Time Bioluminescence Imaging of Glycans on Live Cells
2010 StandoutNobel
Cellular localization of adrenergic receptors in rat and human brain
1986
Works of Brigitte Ilien being referenced
Pirenzepine Promotes the Dimerization of Muscarinic M1 Receptors through a Three-step Binding Process
2009
A μ-opioid receptor-filter assay
1988
Direct and energy‐transfer photolabelling of brain muscarinic acetylcholine receptors
1989
Fluorescence resonance energy transfer to probe human M1 muscarinic receptor structure and drug binding properties
2003
The Neurokinin A Receptor Activates Calcium and cAMP Responses through Distinct Conformational States
2001
Fluorescent Pirenzepine Derivatives as Potential Bitopic Ligands of the Human M1 Muscarinic Receptor
2004
A Rapid and Versatile Method to Label Receptor Ligands Using “Click” Chemistry: Validation with the Muscarinic M1 Antagonist Pirenzepine
2006
Differentiation of solubilized dopamine receptors from spirodecanone binding sites in rat striatum
1980
Solubilized serotonin receptors from rat and dog brain
1982
Solubilization of brain muscarinic, dopaminergic and serotonergic receptors: A critical analysis
1982
Analytical Subcellular Fractionation of Rat Cortex: Resolution of Serotonergic Nerve Endings and Receptors
1983
Variations in endogenous phosphodiesterase activator content of rat aorta
1978
Characterization of solubilized serotonin (S2) receptors in rat brain.
1982
Solubilization of muscarinic acetylcholine receptors from mammalian brain: An analytical approach
1981