Citation Impact
Citing Papers
The Mechanism of Endogenous Receptor Activation Functionally Distinguishes Prototype Canonical and Noncanonical Wnts
2005
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
2003 StandoutScienceNobel
Merlin/ NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane
2005
Hallmarks of Cancer: The Next Generation
2011 Standout
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
1992 StandoutNatureNobel
Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development.
1990
Organizing activity of wingless protein in Drosophila
1993
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Maintenance of functional equivalence during paralogous Hox gene evolution
2000 StandoutNatureNobel
Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1
2011 StandoutNatureNobel
Expression cloning of Siamois, a xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis
1995 StandoutNobel
Diffusible factors in vertebrate embryonic induction
1992
Eomesodermin, a Key Early Gene in Xenopus Mesoderm Differentiation
1996 StandoutNobel
Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development
1990 Nature
Serine Phosphorylation-regulated Ubiquitination and Degradation of β-Catenin
1997
The Drosophila Circadian Network Is a Seasonal Timer
2007 StandoutNobel
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
2007 StandoutNobel
Wnt Signaling and an APC-Related Gene Specify Endoderm in Early C. elegans Embryos
1997 StandoutNobel
The generation of diversity and pattern in animal development
1992 StandoutNobel
Differential molecular interactions of β-catenin and plakoglobin in adhesion, signaling and cancer
1998
Community effects and related phenomena in development
1993 StandoutNobel
Nuclear localization of β-catenin by interaction with transcription factor LEF-1
1996
Oncoprotein Networks
1997
The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain
1990
Axin Directly Interacts with Plakoglobin and Regulates Its Stability
1999
Wnt proteins are lipid-modified and can act as stem cell growth factors
2003 StandoutNature
The 2–5 A system: Modulation of viral and cellular processes through acceleration of RNA degradation
1998
Wnt‐1 as a short‐range signaling molecule
1994
The Hallmarks of Cancer
2000 Standout
The Interpretation of Position in a Morphogen Gradient as Revealed by Occupancy of Activin Receptors
1998 StandoutNobel
Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?
2010
Wnt genes
1992
Drosophila wingless: A paradigm for the function and mechanism of Wnt signaling
1994
Phosphorothioate analogs of 2',5'-oligoadenylate. Enzymatically synthesized 2',5'-phosphorothioate dimer and trimer: unequivocal structural assignment and activation of 2',5'-oligoadenylate-dependent endoribonuclease
1987 StandoutNobel
Wnt signaling: a common theme in animal development
1997 Standout
β-catenin is a target for the ubiquitin–proteasome pathway
1997 Standout
Activin signalling and response to a morphogen gradient
1994 StandoutNatureNobel
Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question
1992 StandoutNobel
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Signal transduction through beta-catenin and specification of cell fate during embryogenesis.
1996
PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling
2001
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
A zonal organization of odorant receptor gene expression in the olfactory epithelium
1993 StandoutNobel
Differential interaction of plakoglobin and β-catenin with the ubiquitin-proteasome system
2000 StandoutNobel
Generation of germline-competent induced pluripotent stem cells
2007 StandoutNatureNobel
Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox geneHox-#150;1.6
1992 StandoutNatureNobel
In pursuit of the functions of the Wnt family of developmental regulators: Insights from Xenopus laevis
1993
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
The adenomatous polyposis coli (APC) tumor suppressor
1997
The midbrain-hindbrain phenotype of Wnt-1−Wnt-1− mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum
1992
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signalling in intact cells
1996
Patterning the Xenopus blastula
1997
The C. elegans gene lin-44, which controls the polarity of certain asymmetric cell divisions, encodes a Wnt protein and acts cell nonautonomously
1995 StandoutNobel
TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice
1993 StandoutNobel
WRM-1 Activates the LIT-1 Protein Kinase to Transduce Anterior/Posterior Polarity Signals in C. elegans
1999 StandoutNobel
Swaying is a mutant allele of the proto-oncogene Wnt-1
1991 StandoutNobel
Cadherins and catenins in development
1996
lin-35 and lin-53, Two Genes that Antagonize a C. elegans Ras Pathway, Encode Proteins Similar to Rb and Its Binding Protein RbAp48
1998 StandoutNobel
Injected Wnt RNA induces a complete body axis in Xenopus embryos
1991
Biological activity of soluble wingless protein in cultured Drosophila imaginal disc cells
1994 Nature
Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein.
1993
Regulation of Neurotrophin-3 Expression by Epithelial-Mesenchymal Interactions: The Role of Wnt Factors
1999 StandoutScienceNobel
β-Trcp couples β-catenin phosphorylation-degradation and regulates Xenopus axis formation
1999
Biochemical characterization of Wnt-Frizzled interactions using a soluble, biologically active vertebrate Wnt protein
1999
The Wnt family of developmental regulators
1992
Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies.
1993 StandoutNobel
Role of Members of the Wnt Gene Family in Human Hematopoiesis
1998
A Soluble Form of Wnt-1 Protein with Mitogenic Activity on Mammary Epithelial Cells
1995
Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney
1998
Induction of the primary dorsalizing center in Xenopus by the Wnt/GSK/β-catenin signaling pathway, but not by Vg1, Activin or Noggin
1997
Increased stability and antiviral activity of 2′‐O‐phosphoglyceryl derivatives of (2′‐5′)oligo(adenylate)
1984
Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds
1993
Secretion and movement of wingless protein in the epidermis of the Drosophila embryo
1991
Interaction of Wnt-1 proteins with the binding protein BiP.
1992
Mutational analysis of mouse Wnt-1 identifies two temperature-sensitive alleles and attributes of Wnt-1 protein essential for transformation of a mammary cell line.
1992
Analysis of the Signaling Activities of Localization Mutants of β-Catenin during Axis Specification in Xenopus
1997
SQV-7, a protein involved in Caenorhabditis elegans epithelial invagination and early embryogenesis, transports UDP-glucuronic acid, UDP- N - acetylgalactosamine, and UDP-galactose
2001 StandoutNobel
Stabilization of β-Catenin by Genetic Defects in Melanoma Cell Lines
1997 Science
A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates β-catenin but its zygotic expression is not essential for the regulation of Armadillo
1997 Nobel
Epithelial Mesenchymal Transition by c-Fos Estrogen Receptor Activation Involves Nuclear Translocation of β-Catenin and Upregulation of β-Catenin/Lymphoid Enhancer Binding Factor-1 Transcriptional Activity
2000
Effect of Wnt-1 and Related Proteins on Gap Junctional Communication in Xenopus Embryos
1991 Science
β-catenin signalling modulates proliferative potential of human epidermal keratinocytes independently of intercellular adhesion
1999
Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin
1994
Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction.
1996
Deletion of an Amino-Terminal Sequence Stabilizes β-Catenin In Vivo and Promotes Hyperphosphorylation of the Adenomatous Polyposis Coli Tumor Suppressor Protein
1996
A Homolog of the armadillo Protein in Drosophila (Plakoglobin) Associated with E-Cadherin
1991 Science
Cell adhesion and the integrin-linked kinase regulate the LEF-1 and β-catenin signaling pathways
1998
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
2001 StandoutNobel
The Taxonomy of Developmental Control in Caenorhabditis elegans
1998 StandoutScienceNobel
Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC −/− Colon Carcinoma
1997 StandoutScience
Somatic mutations of the β-catenin gene are frequent in mouse and human hepatocellular carcinomas
1998
wingless signaling in the Drosophila eye and embryonic epidermis
1996
Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling
1997
Cooperation between the activin and Wnt pathways in the spatial control of organizer gene expression
1998 StandoutNobel
Activity of Wnt-1 as a transmembrane protein.
1993
The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis
1997
Microtubule-mediated transport of organelles and localization of β-catenin to the future dorsal side of Xenopus eggs
1997
NH2-terminal Deletion of β-Catenin Results in Stable Colocalization of Mutant β-Catenin with Adenomatous Polyposis Coli Protein and Altered MDCK Cell Adhesion
1997
MECHANISMS OF WNT SIGNALING IN DEVELOPMENT
1998 Standout
Secretion and mesoderm-inducing activity of the TGF-beta-related domain of Xenopus Vg1.
1993
Two different thresholds of wingless signalling with distinct developmental consequences in the Drosophila midgut.
1995
Epiregulin Is Not Essential for Development of Intestinal Tumors but Is Required for Protection from Intestinal Damage
2004
Differential Nuclear Translocation and Transactivation Potential of β-Catenin and Plakoglobin
1998
Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action
1997
A Localized Wnt Signal Orients Asymmetric Stem Cell Division in Vitro
2013 StandoutScienceNobel
Isolation and expression of two novel Wnt/wingless gene homologues in Drosophila
1992
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 StandoutNobel
Regulation of β-Catenin Levels and Localization by Overexpression of Plakoglobin and Inhibition of the Ubiquitin-Proteasome System
1997
Expression of Wnt-1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion.
1993
Xwnt-11: a maternally expressed Xenopus wnt gene
1993
Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderminducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis
1991
Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development
1992
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
A Role for the Wnt Gene Family in Hematopoiesis: Expansion of Multilineage Progenitor Cells
1997
Solution structure of murine epidermal growth factor: determination of the polypeptide backbone chain-fold by nuclear magnetic resonance and distance geometry.
1987 StandoutNobel
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Expression of two members of the Wnt family during mouse development--restricted temporal and spatial patterns in the developing neural tube.
1991
The Mouse Wnt-1 Gene Can Act Via a Paracrine Mechanism in Transformation of Mammary Epithelial Cells
1992
Cytoskeletal reorganization by soluble Wnt‐3a protein signalling
1998
Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus.
1993
Epidermal growth factor receptor occupancy inhibits vaccinia virus infection
1985 Nature
n-Decyl-NHpppA2′p5′A2′p5′A a phosphatase-resistant, active pppA2′p5′A2′p5′A analog
1985 StandoutNobel
Works of Brian Schryver being referenced
Dephosphorylated Core of 2′-5′ Oligoadenylate Exerts Its Antimitogenic Effect through Mechanisms Different from the 2′-5′A-Dependent Endonuclease
1983
Expression of Betacellulin and Epiregulin Genes in the Mouse Uterus Temporally by the Blastocyst Solely at the Site of Its Apposition Is Coincident with the “Window” of Implantation
1997
Requirement for PAK4 in the Anchorage-independent Growth of Human Cancer Cell Lines
2002
The biochemical properties and transforming potential of human Wnt-2 are similar to Wnt-1.
1992
Secreted int-1 protein is associated with the cell surface.
1990
Mechanism of antiviral activity of (XyloA2′p)2XyloA
1983
Secreted int-1 Protein Is Associated with the Cell Surface
1990
Analogs of (A2'p)nA. Correlation of structure of analogs of ppp(A2'p)2A and (A2'p)2A with stability and biological activity.
1982
Cordycepin analogs of ppp5'A2‘p5'A2‘p5'A (2-5A) inhibit protein synthesis through activation of the 2-5A-dependent endonuclease.
1985
Stereoconfiguration markedly affects the biochemical and biological properties of phosphorothioate analogs of 2-5A core, (A2'p5')2A.
1986
Wnt-1 Regulates Free Pools of Catenins and Stabilizes APC-Catenin Complexes
1996
Properties of Wnt-1 protein that enable cell surface association.
1996