Standout Papers
Citation Impact
Citing Papers
The role of platelet adhesion receptor GPIbα far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis
2006
Shear-induced unfolding triggers adhesion of von Willebrand factor fibers
2007 Standout
Size regulation of von Willebrand factor–mediated platelet thrombi by ADAMTS13 in flowing blood
2005
A mechanosensory complex that mediates the endothelial cell response to fluid shear stress
2005 StandoutNature
Rationally Designed Integrin β3 Mutants Stabilized in the High Affinity Conformation
2008 StandoutNobel
Modulation of Integrin Activation by an Entropic Spring in the β-Knee
2010 StandoutNobel
Mechanisms of Thrombus Formation
2008 Standout
Tyrosine sulfation: a modulator of extracellular protein–protein interactions
2000 StandoutNobel
A shear gradient–dependent platelet aggregation mechanism drives thrombus formation
2009
Von Willebrand factor, platelets and endothelial cell interactions
2003
Von Willebrand factor, a key protein in the exposure of CD62P on platelets
2001
Cancer Metastasis: Building a Framework
2006 Standout
Distinct mechanisms of platelet aggregation as a consequence of different shearing flow conditions.
1998
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
NMR structure of the Euplotes raikovi pheromone E r -23 and identification of its five disulfide bonds 1 1Edited by M. F. Summers
2001 StandoutNobel
Epitope Mapping of Monoclonal Antibody to Integrin αL β2 Hybrid Domain Suggests Different Requirements of Affinity States for Intercellular Adhesion Molecules (ICAM)-1 and ICAM-3 Binding
2005
Ligand and cation binding are dual functions of a discrete segment of the integrin β3 subunit: Cation displacement is involved in ligand binding
1994
Solution Structure of Human von Willebrand Factor Studied Using Small Angle Neutron Scattering
2006
The Structure of a Receptor with Two Associating Transmembrane Domains on the Cell Surface: Integrin αIIbβ3
2009 StandoutNobel
Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling
2003 StandoutNobel
Whole blood coagulation on protein adsorption-resistant PEG and peptide functionalised PEG-coated titanium surfaces
2004 StandoutNobel
Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis
2015 Standout
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Platelets in atherothrombosis
2002
The von Willebrand factor self-association is modulated by a multiple domain interaction
2005
Platelet Activation and Atherothrombosis
2007 Standout
Effects of fluid dynamic forces on vascular cell adhesion.
1996
The coagulation cascade: initiation, maintenance, and regulation
1991 Standout
von Willebrand factor.
1997
Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen
2001
Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y1 receptor–null mice
1999
The biologic and clinical spectrum of Glanzmann's Thrombasthenia: implications of integrin αIIbβ3 for its pathogenesis
1997
Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis
1996 Standout
Diabetes and Atherosclerosis
2002 Standout
Inside-out integrin signalling
1992
Integrin α2-Deficient Mice Develop Normally, Are Fertile, but Display Partially Defective Platelet Interaction with Collagen
2002
The disulfide bridge pattern of snake venom disintegrins, flavoridin and echistatin
1992
Hemodynamic Shear Stress and Its Role in Atherosclerosis
1999 Standout
Resistance to Activated Protein C as a Basis for Venous Thrombosis
1994 Standout
Prospects for the use of antagonists to the platelet glycoprotein IIb/ IIIa receptor to prevent postangioplasty restenosis and thrombosis
1991
Flow-Cytometric Analysis of Mouse Platelet Function
2004
Thrombin-initiated platelet activation in vivo is vWF independent during thrombus formation in a laser injury model
2007
Platelet GPIIb/IIIa antagonists: the first anti-integrin receptor therapeutics.
1997
Kindlin-3 is essential for integrin activation and platelet aggregation
2008
Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen
2000
Topography of Ligand-induced Binding Sites, Including a Novel Cation-sensitive Epitope (AP5) at the Amino Terminus, of the Human Integrin β3 Subunit
1995
Rac recruits high-affinity integrin αvβ3 to lamellipodia in endothelial cell migration
2001
Rho and Rac Take Center Stage
2004 Standout
Adhesive signaling in platelets
1994
Golgi Localization of Carbohydrate Sulfotransferases Is a Determinant of L-selectin Ligand Biosynthesis
2003 StandoutNobel
Protein tyrosine phosphorylation and the adhesive functions of platelets
1991
Surface plasmon resonance detection of blood coagulation and platelet adhesion under venous and arterial shear conditions
2007 StandoutNobel
Inflammation, Atherosclerosis, and Coronary Artery Disease
2005 Standout
Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III
2007
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Increased von Willebrand factor in the endocardium as a local predisposing factor for thrombogenesis in overloaded human atrial appendage
2001
Mechanisms and Consequences of Affinity Modulation of Integrin αVβ3 Detected with a Novel Patch-engineered Monovalent Ligand
1999
Integrins
2002 Standout
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Identification of the platelet ADP receptor targeted by antithrombotic drugs
2001 StandoutNatureNobel
Mechanisms of thrombogenesis in atrial fibrillation: Virchow's triad revisited
2009 Standout
Antibodies to von Willebrand Factor–Cleaving Protease in Acute Thrombotic Thrombocytopenic Purpura
1998 Standout
Cleavage of ultra‐large von Willebrand factor by ADAMTS‐13 under flow conditions
2005
A revised model of platelet aggregation
2000
Identification of the disulfide bond pattern in albolabrin, an RGD-containing peptide from the venon of trimeresurus albolabris: Significance for the express of platelet aggregation inhibitory activity
1991
Peroxynitrite-mediated modification of fibrinogen affects platelet aggregation and adhesion
2002
Antiplatelet therapy: in search of the 'magic bullet'
2003
Extracellular DNA traps promote thrombosis
2010 Standout
Platelet-Endothelial Interactions in Inflamed Mesenteric Venules
1998
The vessel wall and its interactions
2008
An Automatic Braking System That Stabilizes Leukocyte Rolling by an Increase in Selectin Bond Number with Shear
1999
BIOCHEMISTRY AND GENETICS OF VON WILLEBRAND FACTOR
1998 Standout
Polymerase Chain Reaction Selects a Novel Disintegrin Proteinase from CD40-Activated Germinal Center Dendritic Cells
1997
Cell Migration: Integrating Signals from Front to Back
2003 StandoutScience
Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets
2005
Platelet Adhesion Receptors and Their Ligands in Mouse Models of Thrombosis
2007
Binding strength and activation state of single fibrinogen-integrin pairs on living cells
2002
Integrins: Versatility, modulation, and signaling in cell adhesion
1992 Standout
Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage
2006
Defective thrombus formation in mice lacking coagulation factor XII
2005
Platelet Shape Changes and Adhesion Under High Shear Flow
2002
A Critical Role of Platelet Adhesion in the Initiation of Atherosclerotic Lesion Formation
2002
Platelet aggregation induces platelet aggregate stability via SLAM family receptor signaling
2005
Nitric Oxide-Releasing Polymers Containing the [N(O)NO]-Group
1996
Complementary Roles for Receptor Clustering and Conformational Change in the Adhesive and Signaling Functions of Integrin αIIbβ3
1998
Glycoprotein VI–dependent and –independent pathways of thrombus formation in vivo
2006
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Platelets in Inflammation and Thrombosis
2003
Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro–aged or –injured mouse platelets
2003
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
2008 Standout
Synthesis of Sulfotyrosine‐Containing Peptides by Incorporating Fluorosulfated Tyrosine Using an Fmoc‐Based Solid‐Phase Strategy
2015 StandoutNobel
A sulfated metabolite produced bystf3negatively regulates the virulence ofMycobacteriumtuberculosis
2006 StandoutNobel
Integrins and Signal Transduction Pathways: the Road Taken
1995 StandoutScience
A revolution in optical manipulation
2003 StandoutNature
Expression of the von Willebrand Factor in Atrial Endocardium is Increased in Atrial Fibrillation Depending on the Extent of Structural Remodeling
2004
Lasting safe interruption of endarterectomy thrombosis by transiently infused antithrombin peptide D-Phe-Pro-ArgCH2Cl in baboons
1993
Shear-dependent changes in the three-dimensional structure of human von Willebrand factor
1996
Function and Regulation of the β3 Integrins in Hemostasis and Vascular Biology
1995
Involvement of Glycoprotein VI in Platelet Thrombus Formation on Both Collagen and von Willebrand Factor Surfaces Under Flow Conditions
2002
Local delivery of an antithrombin inhibits platelet-dependent thrombosis.
1994
Novel Platelet Inhibitors
2001
Growth Factors and Cancer
1991 StandoutScience
Putting polyphosphates to the test: evidence against platelet-induced activation of factor XII
2013 StandoutNobel
Mechanisms Initiating Platelet Thrombus Formation
1997
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells
2010 StandoutNobel
Focal adhesion kinase in the brain: novel subcellular localization and specific regulation by Fyn tyrosine kinase in mutant mice.
1995 StandoutNobel
Adhesion of platelets to surface-bound fibrinogen under flow
1996
Soluble plasma-derived von Willebrand factor assembles to a haemostatically active filamentous network
2007
Tyrosine phosphorylation of pp125FAK in platelets requires coordinated signaling through integrin and agonist receptors.
1994
A Crucial Role of Glycoprotein VI for Platelet Recruitment to the Injured Arterial Wall In Vivo
2002
Platelet factor 4 binds to low-density lipoprotein receptors and disrupts the endocytic itinerary, resulting in retention of low-density lipoprotein on the cell surface
2002 StandoutNobel
Metal–Organic Frameworks in Biomedicine
2011 Standout
Integrin activation controls metastasis in human breast cancer
2001
Endothelial cells in physiology and in the pathophysiology of vascular disorders.
1998 Standout
Platelet-Mediated Lymphocyte Delivery to High Endothelial Venules
1996 Science
Real-Time Analysis of Mural Thrombus Formation in Various Platelet Aggregation Disorders: Distinct Shear-Dependent Roles of Platelet Receptors and Adhesive Proteins Under Flow
1999
Use of a Monoclonal Antibody Directed against the Platelet Glycoprotein IIb/IIIa Receptor in High-Risk Coronary Angioplasty
1994 Standout
What really is blood compatibility?
2000
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach
2002 StandoutNobel
Adhesion Mechanisms in Platelet Function
2007
Interruption of acute platelet-dependent thrombosis by the synthetic antithrombin D-phenylalanyl-L-prolyl-L-arginyl chloromethyl ketone.
1988
Structures of Glycoprotein Ibα and Its Complex with von Willebrand Factor A1 Domain
2002 Science
Works of Brian Savage being referenced
Mechanisms of platelet aggregation
2001
Interaction of Integrin αIIbβ3 with Multiple Fibrinogen Domains during Platelet Adhesion
1995
Initiation of Platelet Adhesion by Arrest onto Fibrinogen or Translocation on von Willebrand Factor
1996 Standout
Influence of Fibrillar Collagen Structure on the Mechanisms of Platelet Thrombus Formation Under Flow
1999
Nucleotide Polymorphisms in the α2 Gene Define Multiple Alleles That Are Associated With Differences in Platelet α2β1 Density
1998
The relation of platelet density to platelet age: survival of low- and high-density 111indium-labeled platelets in baboons
1986
Modulation of platelet function through adhesion receptors. A dual role for glycoprotein IIb-IIIa (integrin alpha IIb beta 3) mediated by fibrinogen and glycoprotein Ib-von Willebrand factor.
1992
Selective recognition of adhesive sites in surface-bound fibrinogen by glycoprotein IIb-IIIa on nonactivated platelets
1991
Binding of the snake venom-derived proteins applaggin and echistatin to the arginine-glycine-aspartic acid recognition site(s) on platelet glycoprotein IIb.IIIa complex inhibits receptor function.
1990
Agkistrodon piscivorus piscivorus platelet aggregation inhibitor: a potent inhibitor of platelet activation.
1989
The relation of platelet density to platelet age: survival of low- and high-density 111indium-labeled platelets in baboons
1986
Specific Synergy of Multiple Substrate–Receptor Interactions in Platelet Thrombus Formation under Flow
1998
Functional self-association of von Willebrand factor during platelet adhesion under flow
2001
Platelet interactions with Dacron vascular grafts. A model of acute thrombosis in baboons.
1985