Citation Impact
Citing Papers
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels
2006 StandoutNobel
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
Regiospecific Inverse-Electron-Demand Diels–Alder Reaction of Simultaneously Electrogenerated Diene and Dienophile: An Expeditious Route to Polyfunctionalized 1,4-Benzoxazine Derivatives
2002
Autophagosomes form at ER–mitochondria contact sites
2013 StandoutNature
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
2009 StandoutNature
Apoptosis in the nervous system
2000 StandoutNature
Oxidation of Unactivated Primary Aliphatic Amines Catalyzed by an Electrogenerated 3,4‐Azaquinone Species: A Small‐Molecule Mimic of Amine Oxidases
2003
Mechanisms of Neuronal Degeneration in Alzheimer's Disease
1996
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Regulation of hippocampal synaptic plasticity by cyclic AMP-dependent protein kinases
2003
Sigma 1 Receptor Agonists Act as Neuroprotective Drugs Through Inhibition of Inducible Nitric Oxide Synthase
2006
Balancing Acts
2004 Standout
Microglia Activated with the Toll-Like Receptor 9 Ligand CpG Attenuate Oligomeric Amyloid β Neurotoxicity in in Vitro and in Vivo Models of Alzheimer’s Disease
2009
A review of specific dietary antioxidants and the effects on biochemical mechanisms related to neurodegenerative processes
2002
Environmentally Friendly Chemoselective Oxidation of Primary Aliphatic Amines by Using a Biomimetic Electrocatalytic System
2007
Comparative analysis of cytotoxic, genotoxic and antioxidant effects of 2,2,4,7-tetramethyl-1,2,3,4-tetrahydroquinoline and ethoxyquin on human lymphocytes
2006
Improvement by nefiracetam of β‐amyloid‐(1‐42)‐induced learning and memory impairments in rats
1999
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
2015 Standout
Decoding ALS: from genes to mechanism
2016 StandoutNature
Synthesis and anticancer effect of chrysin derivatives
2003
Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization
2018 StandoutNatureNobel
Bilateral Injections of Amyloid-β 25-35 into the Amygdala of Young Fischer Rats: Behavioral, Neurochemical, and Time Dependent Histopathological Effects
1997
Review: Alzheimer's Amyloid β-Peptide-Associated Free Radical Oxidative Stress and Neurotoxicity
2000
σ-1 Receptors (σ1 Binding Sites) Form Raft-Like Microdomains and Target Lipid Droplets on the Endoplasmic Reticulum: Roles in Endoplasmic Reticulum Lipid Compartmentalization and Export
2003
Quinoline-based compounds as modulators of HIV transcription through NF-κB and Sp1 inhibition
2010
Cellular Distribution and Functions of P2 Receptor Subtypes in Different Systems
2004
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
β-Amyloid1–42 Binds to α7 Nicotinic Acetylcholine Receptor with High Affinity
2000
Intracellular Dynamics of σ-1 Receptors (σ1 Binding Sites) in NG108-15 Cells
2003
Correlation between cognitive deficits and Aβ deposits in transgenic APP+PS1 mice
2001
Targeting apoptosis in cancer therapy
2020 Standout
??-1 Receptor Ligands
2004
Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
2010 StandoutNature
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
Emerging Biological Principles of Metastasis
2017 Standout
Alzheimer's Disease
2010 Standout
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
2007 StandoutNatureNobel
Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
2013 Standout
Cross-talk between calcium and cAMP-dependent intracellular signaling pathways. Implications for synergistic secretion in T84 colonic epithelial cells and rat pancreatic acinar cells.
1995 StandoutNobel
Role of Free Radicals in the Neurodegenerative Diseases
2001 Standout
Alzheimer's Disease
2004 Standout
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
MET signalling: principles and functions in development, organ regeneration and cancer
2010
Intensive Insulin Therapy in the Medical ICU
2006 Standout
Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival
2007 Standout
Management of Diabetes and Hyperglycemia in Hospitals
2004
Efficient synthesis of functionalized dihydroquinolines, quinolines and dihydrobenzo[b]azepine via an iron(iii ) chloride-catalyzed intramolecular alkyne–carbonyl metathesis of alkyne tethered 2-amino benzaldehyde/acetophenone derivatives
2014
Iron Catalysis in Organic Synthesis
2015 Standout
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Applications of the Morris water maze in the study of learning and memory
2001 Standout
An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain
2003 StandoutNobel
A Biomimetic Electrocatalytic System for the Atom-Economical Chemoselective Synthesis of Secondary Amines
2009
Place cell firing correlates with memory deficits and amyloid plaque burden in Tg2576 Alzheimer mouse model
2008 StandoutNobel
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
Alzheimer's disease: a re-examination of the amyloid hypothesis
1998
Iodine-Catalyzed Aza-Diels–Alder Reactions of Aliphatic N-Arylaldimines
2009
A new approach to 2,2-disubstituted chromenes and tetrahydroquinolines through intramolecular cyclization of chiral 3,4-epoxy alcohols
2004
Neuroprotective Effect of σ1-Receptor Ligand 4-Phenyl-1-(4-Phenylbutyl) Piperidine (PPBP) Is Linked to Reduced Neuronal Nitric Oxide Production
2001
Sigma Receptors and Cancer
2004
Spatial distribution of calcium channels and cytosolic calcium transients in growth cones and cell bodies of sympathetic neurons.
1988 StandoutNobel
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Nongenomic Steroid Action: Controversies, Questions, and Answers
2003
Activation of a potassium current by rapid photochemically generated step increases of intracellular calcium in rat sympathetic neurons.
1987 StandoutNobel
Hydrogen Autotransfer in the N-Alkylation of Amines and Related Compounds using Alcohols and Amines as Electrophiles
2009 Standout
Sigma-1 receptors at galactosylceramide-enriched lipid microdomains regulate oligodendrocyte differentiation
2004
Rigid Phencyclidine Analogues. Binding to the Phencyclidine and σ1 Receptors
1998
Cis−Trans Isomerization of Organic Molecules and Biomolecules: Implications and Applications
2003
Fluorescent Sensors for Measuring Metal Ions in Living Systems
2014 Standout
Elevated Src family kinase activity stabilizes E-cadherin-based junctions and collective movement of head and neck squamous cell carcinomas
2014
The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors.
1990 StandoutNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Artificial Molecular Machines
2015 Standout
Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance
2017 Standout
A novel tert-amino effect based approach to 1,2,3,4-tetrahydroquinoline-2-spirocycloalkanes
2006
Resistance to Anti-Angiogenic Therapy in Cancer—Alterations to Anti-VEGF Pathway
2018
Sequential activation and lethal hit measured by [Ca2+]i in individual cytolytic T cells and targets.
1987 StandoutNobel
Electrochemically Induced Cascade Reaction for the Assembly of Libraries of Biologically Relevant 1,4-Benzoxazine Derivatives
2006
Rat brain serotonin receptors in Xenopus oocytes are coupled by intracellular calcium to endogenous channels.
1987 StandoutNobel
HDACs and HDAC Inhibitors in Cancer Development and Therapy
2016
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
6-Nitro-1,2,3,4-tetrahydroquinoline-4-carboxylic Esters and 7-Nitro-3,4-dihydroquinoxaline- 1(2H)-carboxylic Esters by a Tandem Reductive Amination-SNAr Reaction
2010
Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.
1990 Standout
Aromatic Trifluoromethylation with Metal Complexes
2011 Standout
Amyloid-β peptide–Receptor for Advanced Glycation Endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: A proinflammatory pathway in Alzheimer disease
1997
Crosslinkage of B lymphocyte surface immunoglobulin by anti-Ig or antigen induces prolonged oscillation of intracellular ionized calcium.
1987 StandoutNobel
Simultaneously electrogenerated diene and dienophile: A unique access to novel polyfunctionalized 1,4-benzoxazine derivatives as neuroprotective agents
2005
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
RIM1α phosphorylation at serine-413 by protein kinase A is not required for presynaptic long-term plasticity or learning
2008 StandoutNobel
Environmentally friendly organic synthesis using bismuth compounds. Bismuth(III) bromide catalyzed synthesis of substituted tetrahydroquinoline derivatives
2008
Works of Brian Lockhart being referenced
S49076 Is a Novel Kinase Inhibitor of MET, AXL, and FGFR with Strong Preclinical Activity Alone and in Association with Bevacizumab
2013
HDAC inhibition does not induce estrogen receptor in human triple-negative breast cancer cell lines and patient-derived xenografts
2014
A convenient extension of the Wessely–Moser rearrangement for the synthesis of substituted alkylaminoflavones as neuroprotective agents in vitro
2000
Synthesis of novel orthoalkylaminophenol derivatives as potent neuroprotective agents in vitro
1999
Distinct neuroprotective profiles for σ ligands against N-methyl-d-aspartate (NMDA), and hypoxia-mediated neurotoxicity in neuronal culture toxicity studies
1995
Targeting Bcl-2/Bcl-XL Induces Antitumor Activity in Uveal Melanoma Patient-Derived Xenografts
2014
Specific Oncogenic Activity of the Src-Family Tyrosine Kinase c-Yes in Colon Carcinoma Cells
2011
Neuroprotective effects of modulators of P2 receptors in primary culture of CNS neurones
1999
Protective effect of the antioxidant 6-ethoxy-2,2-pentamethylen-1,2-dihydroquinoline (S 33113) in models of cerebral neurodegeneration
2001
New quinolinic derivatives as centrally active antioxidants
2000
Neuroprotective and anti-amnesic potentials of sigma (σ) receptor ligands
1997
Inhibitors of free radical formation fail to attenuate direct β‐amyloid25–35 peptide‐mediated neurotoxicity in rat hippocampal cultures
1994
Amnesia induced in mice by centrally administered β-amyloid peptides involves cholinergic dysfunction
1996
Synthesis, Structure, and Neuroprotective Properties of Novel Imidazolyl Nitrones
2000
Only a Subset of Met-Activated Pathways Are Required to Sustain Oncogene Addiction
2009
Novel 2-Alkylamino-1,4-benzoxazine Derivatives as Potent Neuroprotective Agents: Structure−Activity Relationship Studies
2005
Synthesis and in Vitro Evaluation of New 8-Amino-1,4-benzoxazine Derivatives as Neuroprotective Antioxidants
1999