Citation Impact
Citing Papers
Cell entry mechanisms of SARS-CoV-2
2020 Standout
A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients
2023 StandoutNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)
2013 StandoutNobel
Current progress in development of hepatitis C virus vaccines
2013
Vaccination to prevent T cell subversion can protect against persistent hepacivirus infection
2019
General Prediction of Peptide-MHC Binding Modes Using Incremental Docking: A Proof of Concept
2018
Determining cell type abundance and expression from bulk tissues with digital cytometry
2019 Standout
Prospects for Prophylactic and Therapeutic Vaccines Against Hepatitis C Virus
2012
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
2009 StandoutNature
Elevated Pre–Antiretroviral Therapy CD39+CD8+ T Cell Frequency Is Associated With Early Mortality in Advanced Human Immunodeficiency Virus/Tuberculosis Co-infection
2017 StandoutNobel
Analysis of long-term persistence of resistance mutations within the hepatitis C virus NS3 protease after treatment with telaprevir or boceprevir
2011
Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27–restricted human immune response
2009
T cell exhaustion
2011 Standout
Immune Responses to Hepatitis C Virus (HCV) Infection and the Prospects for an Effective HCV Vaccine or Immunotherapies
2013
The evolving landscape of biomarkers for checkpoint inhibitor immunotherapy
2019 Standout
Coinfection With HIV-1 and HCV—A One-Two Punch
2009
Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver cultures
2010 StandoutNobel
Designing an HCV vaccine: a unique convergence of prevention and therapy?
2017
Understanding the tumor immune microenvironment (TIME) for effective therapy
2018 Standout
Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity
2011 Standout
Host Genetic Factors and Antiviral Immune Responses to Hepatitis C Virus
2008
Sequential Bottlenecks Drive Viral Evolution in Early Acute Hepatitis C Virus Infection
2011
A Humanized Mouse Model to Study Hepatitis C Virus Infection, Immune Response, and Liver Disease
2011 StandoutNobel
Strategies for development of dengue virus inhibitors
2010
PD-1/PD-L1 pathway and T-cell exhaustion in chronic hepatitis virus infection
2010
Structural biology in fragment-based drug design
2010
CD39 Expression Identifies Terminally Exhausted CD8+ T Cells
2015
Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity
2010
Hepatitis C virus–specific CD4+ T cell phenotype and function in different infection outcomes
2020
Immune Responses to HCV and Other Hepatitis Viruses
2014
Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence
2009
Hepatitis C virus infection
2017
Adaptive Immunity to the Hepatitis C Virus
2010
Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells
2013
Immune Memory and Exhaustion: Clinically Relevant Lessons from the LCMV Model
2015
Regulation and Function of the PD-L1 Checkpoint
2018 Standout
Molecular mechanisms of T cell co-stimulation and co-inhibition
2013 Standout
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
2015 Standout
Extra-epitopic hepatitis C virus polymorphisms confer resistance to broadly neutralizing antibodies by modulating binding to scavenger receptor B1
2017
Predicting HLA CD4 Immunogenicity in Human Populations
2018
Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals
2020 Standout
Transforming fragments into candidates: small becomes big in medicinal chemistry
2009
Resistance to Direct Antiviral Agents in Patients With Hepatitis C Virus Infection
2009
Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19
2020 Standout
Cancer immunotherapy comes of age
2011 StandoutNature
Inhibitory Molecules That Regulate Expansion and Restoration of HCV-Specific CD4+ T Cells in Patients With Chronic Infection
2011
T cell immunity to hepatitis C virus: Lessons for a prophylactic vaccine
2020
Recent progress in fragment-based lead discovery
2009
Regulation of type I interferon responses
2013 Standout
Inflammatory signaling compromises cell responses to interferon alpha
2011
Challenges and Promise of a Hepatitis C Virus Vaccine
2019
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
A Hepatitis C Virus (HCV) Vaccine Comprising Envelope Glycoproteins gpE1/gpE2 Derived from a Single Isolate Elicits Broad Cross-Genotype Neutralizing Antibodies in Humans
2013 StandoutNobel
Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization
2008
Coexpression of PD-1, 2B4, CD160 and KLRG1 on Exhausted HCV-Specific CD8+ T Cells Is Linked to Antigen Recognition and T Cell Differentiation
2010
Elucidation of Hepatitis C Virus Transmission and Early Diversification by Single Genome Sequencing
2012
T cell responses in hepatitis C: the good, the bad and the unconventional
2011
Molecular and cellular insights into T cell exhaustion
2015 Standout
A guide to cancer immunotherapy: from T cell basic science to clinical practice
2020 Standout
Spontaneous Clearance of Chronic Hepatitis C Virus Infection Is Associated With Appearance of Neutralizing Antibodies and Reversal of T-Cell Exhaustion
2012
Tumor Necrosis Factor Inhibits Spread of Hepatitis C Virus Among Liver Cells, Independent From Interferons
2017 StandoutNobel
Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response
2018 Standout
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Acceleration of Hepatitis C Virus Envelope Evolution in Humans Is Consistent with Progressive Humoral Immune Selection during the Transition from Acute to Chronic Infection
2010
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Utility of Humanized BLT Mice for Analysis of Dengue Virus Infection and Antiviral Drug Testing
2013 StandoutNobel
Identification, Molecular Cloning, and Analysis of Full-Length Hepatitis C Virus Transmitted/Founder Genotypes 1, 3, and 4
2015 StandoutNobel
Tracking the Evolution of MultipleIn VitroHepatitis C Virus Replicon Variants under Protease Inhibitor Selection Pressure by 454 Deep Sequencing
2010
Will There Be a Vaccine to Prevent HCV Infection?
2014
Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro
2012 StandoutNobel
Recombinant Hepatitis C Virus Envelope Glycoprotein Vaccine Elicits Antibodies Targeting Multiple Epitopes on the Envelope Glycoproteins Associated with Broad Cross-Neutralization
2014 StandoutNobel
Characterization of nonprimate hepacivirus and construction of a functional molecular clone
2015 StandoutNobel
Acute Liver Damage Associated with Innate Immune Activation in a Small Nonhuman Primate Model of Hepacivirus Infection
2016
Early Interferon Therapy for Hepatitis C Virus Infection Rescues Polyfunctional, Long-Lived CD8 + Memory T Cells
2008
Hepatitis C Virus Transmission Bottlenecks Analyzed by Deep Sequencing
2010
Fundamental Mechanisms of Immune Checkpoint Blockade Therapy
2018 StandoutNobel
A Recombinant Hepatitis C Virus Genotype 1a E1/E2 Envelope Glycoprotein Vaccine Elicits Antibodies That Differentially Neutralize Closely Related 2a Strains through Interactions of the N-Terminal Hypervariable Region 1 of E2 with Scavenger Receptor B1
2019 StandoutNobel
Peptide-binding specificity prediction using fine-tuned protein structure prediction networks
2023 StandoutNobel
Progenitor and Terminal Subsets of CD8 + T Cells Cooperate to Contain Chronic Viral Infection
2012 Science
Regulation of Trypanosoma cruzi-Induced Myocarditis by Programmed Death Cell Receptor 1
2011 StandoutNobel
Response of Hepatitis C Virus to Long-Term Passage in the Presence of Alpha Interferon: Multiple Mutations and a Common Phenotype
2013 StandoutNobel
High-Programmed Death-1 Levels on Hepatitis C Virus-Specific T Cells during Acute Infection Are Associated with Viral Persistence and Require Preservation of Cognate Antigen during Chronic Infection
2008
Increased Replicative Fitness Can Lead to Decreased Drug Sensitivity of Hepatitis C Virus
2014 StandoutNobel
Viral persistence, liver disease, and host response in a hepatitis C–like virus rat model
2017 StandoutNobel
Replicons of a Rodent Hepatitis C Model Virus Permit Selection of Highly Permissive Cells
2019 StandoutNobel
Role of the E2 Hypervariable Region (HVR1) in the Immunogenicity of a Recombinant Hepatitis C Virus Vaccine
2018 StandoutNobel
A Hepatitis C Virus Envelope Polymorphism Confers Resistance to Neutralization by Polyclonal Sera and Broadly Neutralizing Monoclonal Antibodies
2016
The Frequency of CD127 + Hepatitis C Virus (HCV)-Specific T Cells but Not the Expression of Exhaustion Markers Predicts the Outcome of Acute HCV Infection
2013 StandoutNobel
Characterization of Human Antiviral Adaptive Immune Responses during Hepatotropic Virus Infection in HLA-Transgenic Human Immune System Mice
2013 StandoutNobel
Immune control and failure in HCV infection—tipping the balance
2014
A spatial view of the CD8+ T‐cell response: the case of HCV
2011
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Modified E2 Glycoprotein of Hepatitis C Virus Enhances Proinflammatory Cytokines and Protective Immune Response
2022 StandoutNobel
De novo design of protein logic gates
2020 StandoutScienceNobel
Works of Brian E. Nolan being referenced
Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence
2012
Spontaneous Control of HCV Is Associated With Expression of HLA-B*57 and Preservation of Targeted Epitopes
2010
High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8 + and CD4 + T Cells during Acute HCV Infection, Irrespective of Clinical Outcome
2007
Defining the directionality and quality of influenza virus–specific CD8+ T cell cross-reactivity in individuals infected with hepatitis C virus
2008
Temporal Dynamics of a Predominant Protease Inhibitor–Resistance Mutation in a Treatment-Naive, Hepatitis C Virus–Infected Individual
2009
Multiplex analysis of cytokines as biomarkers that differentiate benign and malignant thyroid diseases
2008
Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors
2008
Viral Sequence Evolution in Acute Hepatitis C Virus Infection
2007
Hepatitis C Virus (HCV) Sequence Variation Induces an HCV-Specific T-Cell Phenotype Analogous to Spontaneous Resolution
2009
Immunologic evidence for lack of heterologous protection following resolution of HCV in patients with non–genotype 1 infection
2007
Human leukocyte antigen–associated sequence polymorphisms in hepatitis C virus reveal reproducible immune responses and constraints on viral evolution†
2007