Citation Impact
Citing Papers
Computational Thermostabilization of an Enzyme
2005 StandoutScienceNobel
Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
Rationally Designed Integrin β3 Mutants Stabilized in the High Affinity Conformation
2008 StandoutNobel
Feedback Regulation of β-Arrestin1 Function by Extracellular Signal-regulated Kinases
1999 StandoutNobel
Recombinant Adenovirus Expressing Von Hippel-Lindau-Mediated Cell Cycle Arrest Is Associated with the Induction of Cyclin-Dependent Kinase Inhibitor p27Kip1
1998
Angiogenesis inhibition: A review
1994
Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal
1993
Suppression of tumor growth through disruption of hypoxia-inducible transcription
2000 StandoutNobel
RAS oncogenes: the first 30 years
2003
Determinants of Nuclear and Cytoplasmic Ubiquitin-mediated Degradation of MyoD
2003 StandoutNobel
Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis
1996 Standout
Getting the glycosylation right: Implications for the biotechnology industry
1996
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
1995 Standout
The structure of Escherichia coli cytosine deaminase 1 1Edited by I. A. Wilson
2002
The activation of phosphatidylinositol 3-kinase by Ras
1994
Enzyme and Pathway Engineering for Suicide Gene Therapy
2006
Distinct Pathways of Gi- and Gq-mediated Mitogen-activated Protein Kinase Activation
1995 StandoutNobel
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
1995 StandoutNature
The Nuclear Ubiquitin-Proteasome System Degrades MyoD
2001 StandoutNobel
RAS Is Regulated by the let-7 MicroRNA Family
2005 Standout
Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
1995 Standout
Phosphatidylinositol-3-OH kinase direct target of Ras
1994 StandoutNature
A role for the Drosophila neurogenic genes in mesoderm differentiation
1991 StandoutNobel
Involvement of p21ras in activation of extracellular signal-regulated kinase 2
1992 Nature
Exploiting tumour hypoxia in cancer treatment
2004 Standout
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
1992 Standout
The 1.14 Å Crystal Structure of Yeast Cytosine Deaminase
2003
Inhibition of erythropoietin production by phorbol ester is associated with down-regulation of protein kinase C-α isoenzyme in hepatoma cells
1991
Gene directed enzyme/prodrug therapy of cancer: Historical appraisal and future prospectives
2001
Purification and Characterization of Hypoxia-inducible Factor 1
1995 StandoutNobel
Biphasic activation of p21ras by endothelin-1 sequentially activates the ERK cascade and phosphatidylinositol 3-kinase
1997
Exploiting the hypoxic cancer cell: mechanisms and therapeutic strategies
2000
T cell antigen CD28 binds to the GRB‐2/SOS complex, regulators of p21ras
1995
Herpes Simplex Virus Thymidine Kinase Gene Transfer for Controlled Graft-versus-Host Disease and Graft-versus-Leukemia: Clinical Follow-up and Improved New Vectors
1998
Cell Migration: A Physically Integrated Molecular Process
1996 Standout
β-Arrestin1 Mediates Insulin-like Growth Factor 1 (IGF-1) Activation of Phosphatidylinositol 3-Kinase (PI3K) and Anti-apoptosis
2003 StandoutNobel
Protein modules and signalling networks
1995 StandoutNature
Monocyte Colony-stimulating Factor Stimulates Binding of Phosphatidylinositol 3-Kinase to Grb2·Sos Complexes in Human Monocytes
1995
AKT/PKB Signaling: Navigating the Network
2017 Standout
Tumor-activated Prodrugs—A New Approach to Cancer Therapy
2004
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
2000 StandoutNature
Transformation of Mammalian Cells by Constitutively Active MAP Kinase Kinase
1994 StandoutScience
Hypoxia and Mitochondrial Inhibitors Regulate Expression of Glucose Transporter-1 via Distinct Cis-acting Sequences
1995 StandoutNobel
Diversity among the beta subunits of heterotrimeric GTP-binding proteins: Characterization of a novel beta-subunit cDNA
1992
Molecular mechanisms of action of antisense drugs
1999
Phosphatidylinositol 3-Kinase Is an Early Intermediate in the Gβγ-mediated Mitogen-activated Protein Kinase Signaling Pathway
1996 StandoutNobel
Cytosine deaminase. The roles of divalent metal ions in catalysis.
1993
Gz, a guanine nucleotide-binding protein with unique biochemical properties.
1990 StandoutNobel
The myoD Gene Family: Nodal Point During Specification of the Muscle Cell Lineage
1991 Science
On the Crawling of Animal Cells
1993 Science
G protein beta gamma subunits. Simplified purification and properties of novel isoforms.
1994 StandoutNobel
Proteasome regulation of activation-induced T cell death
1997 StandoutNobel
Transcription Factors, Normal Myeloid Development, and Leukemia
1997
A G Protein γ Subunit Shares Homology with ras Proteins
1989 Science
Rbx1, a Component of the VHL Tumor Suppressor Complex and SCF Ubiquitin Ligase
1999 StandoutScienceNobel
Chemical Glycobiology
2001 StandoutScienceNobel
Interaction of CTLA-4 with AP50, a clathrin-coated pit adaptor protein
1997 StandoutNobel
Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C
1992 StandoutScience
G Proteins and Regulation of Adenylyl Cyclase
1989 StandoutNobel
Receptor stimulated accumulation of phosphatidylinositol (3,4,5)-trisphosphate by G-protein mediated pathways in human myeloid derived cells.
1993
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types.
1993
Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling
1998
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
2001 StandoutNobel
Effect of phorbol esters on protein kinase C-zeta.
1992
G protein beta gamma subunits synthesized in Sf9 cells. Functional characterization and the significance of prenylation of gamma
1992 StandoutNobel
Activation of Mitogen-Activated Protein Kinase Kinase by v-Raf in NIH 3T3 Cells and in Vitro
1992 StandoutScience
Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery
1997 Standout
Dioxin-dependent activation of murine Cyp1a-1 gene transcription requires protein kinase C-dependent phosphorylation.
1992
Enzyme-Responsive Snap-Top Covered Silica Nanocontainers
2008 StandoutNobel
The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans
1995 StandoutNobel
Role for c-myc in Activation-Induced Apoptotic Cell Death in T Cell Hybridomas
1992 Science
Chemoenzymatic elaboration of monosaccharides using engineered cytochrome P450 BM3 demethylases
2009 StandoutNobel
Role of βγ Subunits of G Proteins in Targeting the β-Adrenergic Receptor Kinase to Membrane-Bound Receptors
1992 StandoutScienceNobel
Phorbol ester inhibits erythropoietin production in human hepatoma cells (Hep G2)
1992 StandoutNobel
Superiority of yeast over bacterial cytosine deaminase for enzyme/prodrug gene therapy in colon cancer xenografts.
1999
Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia.
1993 StandoutNobel
Creatine and Creatinine Metabolism
2000 Standout
Diversity of G Proteins in Signal Transduction
1991 StandoutScience
Transcription Factors, Normal Myeloid Development, and Leukemia
1997
G protein gamma subunits contain a 20-carbon isoprenoid.
1990 StandoutNobel
Works of Brian E. Huber being referenced
Alterations in tumor angiogenesis associated with stable expression of the HIV tat gene
1992
Tumour-specific inhibition of lymphoma growth by an antisense oligodeoxynucleotide
1990
The major form of the murine asialoglycoprotein receptor: cDNA sequence and expression in liver, testis and epididymis
1994
Transcriptional Regulatory Sequences of Carcinoembryonic Antigen: Identification and Use with Cytosine Deaminase for Tumor-Specific Gene Therapy
1995
In vivo antitumor activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase.
1993
Gene Therapy in the Treatment of Cancer
1998
Enzyme/prodrug gene therapy: comparison of cytosine deaminase/5-fluorocytosine versus thymidine kinase/ganciclovir enzyme/prodrug systems in a human colorectal carcinoma cell line.
1995
Partial down‐regulation of protein kinase C reverses the growth inhibitory effect of phorbol esters on HepG2 cells
1990
Localization of the codA gene on the Escherichia coli chromosome
1993
Ligand-induced modulation of the hepatic receptor for asialoglycoproteins in the human hepatoblastoma cell line, Hep G2.
1987
Analysis of c-myc expression in a human hepatoma cell line.
1987
Impaired proliferation and tumorigenicity induced by CCAAT/enhancer-binding protein.
1996
Characterization of a transforming N-ras gene in the human hepatoma cell line Hep G2: additional evidence for the importance of c-myc and ras cooperation in hepatocarcinogenesis.
1990
A first step in the development of gene therapy for colorectal carcinoma: cloning, sequencing, and expression of Escherichia coli cytosine deaminase.
1993
Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase.
1994
Association of p21ras with phosphatidylinositol 3-kinase.
1991