Standout Papers

Anchor extension: a structure-guided approach to design cyclic peptides tar... 2019 2026 2021 2023 44
  1. Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites (2021)
    Parisa Hosseinzadeh, P. R. Watson et al. Nature Communications
  2. A computational method for design of connected catalytic networks in proteins (2019)
    Brian D. Weitzner, Yakov Kipnis et al. Protein Science

Citation Impact

Citing Papers

An enumerative algorithm for de novo design of proteins with diverse pocket structures
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Global analysis of protein folding using massively parallel design, synthesis, and testing
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Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN
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Comprehensive computational design of ordered peptide macrocycles
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Origins of coevolution between residues distant in protein 3D structures
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De novo design of transmembrane β barrels
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Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
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Protein structure determination using metagenome sequence data
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Hallucinating symmetric protein assemblies
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Accurate computational design of multipass transmembrane proteins
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Rapid and automated design of two-component protein nanomaterials using ProteinMPNN
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Sculpting conducting nanopore size and shape through de novo protein design
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Computational Stabilization of a Non‐Heme Iron Enzyme Enables Efficient Evolution of New Function
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Hierarchical design of pseudosymmetric protein nanocages
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Expansive discovery of chemically diverse structured macrocyclic oligoamides
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Incorporation of sensing modalities into de novo designed fluorescence-activating proteins
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Computational design of soluble and functional membrane protein analogues
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A suite of designed protein cages using machine learning and protein fragment-based protocols
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Recent advances in de novo protein design: Principles, methods, and applications
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De novo design of allosterically switchable protein assemblies
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De novo design of immunoglobulin-like domains
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Accurate de novo design of heterochiral protein–protein interactions
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Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions
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HMMER web server: interactive sequence similarity searching
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Hydrophobic mismatch drives self-organization of designer proteins into synthetic membranes
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Pfam: the protein families database
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A new coronavirus associated with human respiratory disease in China
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Improving de novo protein binder design with deep learning
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Accurate design of co-assembling multi-component protein nanomaterials
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The road to fully programmable protein catalysis
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Chemical shift-based methods in NMR structure determination
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Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
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The RCSB Protein Data Bank: redesigned web site and web services
2010
A structure-based computational workflow to predict liability and binding modes of small molecules to hERG
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Advances in protein structure prediction and design
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The carbohydrate-active enzymes database (CAZy) in 2013
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Improved protein structure refinement guided by deep learning based accuracy estimation
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The RCSB Protein Data Bank: new resources for research and education
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The coming of age of de novo protein design
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The computational prediction of protein assemblies
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Design of multi-scale protein complexes by hierarchical building block fusion
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Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
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Antibody modeling using the Prediction of ImmunoGlobulin Structure (PIGS) web server
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The emerging role of computational design in peptide macrocycle drug discovery
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SWISS-MODEL: homology modelling of protein structures and complexes
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Constructing arrays of proteins
2013
Computational Prediction of the Heterodimeric and Higher-Order Structure of gpE1/gpE2 Envelope Glycoproteins Encoded by Hepatitis C Virus
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Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1
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The Crucial Role of Methodology Development in Directed Evolution of Selective Enzymes
2019
Computational design of mechanically coupled axle-rotor protein assemblies
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De novo design of small beta barrel proteins
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Networks of electrostatic and hydrophobic interactions modulate the complex folding free energy surface of a designed βα protein
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The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design
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Large-scale determination of previously unsolved protein structures using evolutionary information
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Directed evolution methods for overcoming trade‐offs between protein activity and stability
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Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody
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Validation of de novo designed water‐soluble and transmembrane β‐barrels by in silico folding and melting
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Sequence co-evolution gives 3D contacts and structures of protein complexes
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Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site
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Reconfigurable asymmetric protein assemblies through implicit negative design
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Works of Brian D. Weitzner being referenced

An Integrated Framework Advancing Membrane Protein Modeling and Design
2015
Benchmarking and Analysis of Protein Docking Performance in Rosetta v3.2
2011
A Framework to Simplify Combined Sampling Strategies in Rosetta
2015
Will Widgets and Semantic Tagging Change Computational Biology?
2010
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Serverification of Molecular Modeling Applications: The Rosetta Online Server That Includes Everyone (ROSIE)
2013
Blind prediction performance of RosettaAntibody 3.0: Grafting, relaxation, kinematic loop modeling, and full CDR optimization
2014
RosettaAntibodyDesign (RAbD): A general framework for computational antibody design
2018
A computational method for design of connected catalytic networks in proteins
2019 StandoutNobel
Integration of the Rosetta suite with the python software stack via reproducible packaging and core programming interfaces for distributed simulation
2019
Rankless by CCL
2026