Citation Impact
Citing Papers
Marijuana and the Cannabinoids
2007
Threshold Models for Combination Data from Reproductive and Developmental Experiments
1995
The endocannabinoid nervous system
2001
Pharmacology of Cannabinoid CB 1 and CB 2 Receptors
1997
Cannabinoid WIN 55,212-2 Regulates TRPV1 Phosphorylation in Sensory Neurons
2006
The endocannabinoid system as a target for therapeutic drugs
2000
Evaluation of Cannabinoid Receptor Agonists and Antagonists Using the Guanosine-5′-O-(3-[35S]thio)-triphosphate Binding Assay in Rat Cerebellar Membranes
1998
Cannabinoids Cause Central Sympathoexcitation and Bradycardia in Rabbits
2000
Comparative Receptor Binding Analyses of Cannabinoid Agonists and Antagonists
1998
Cannabinoid-Induced Hypotension and Bradycardia in Rats Is Mediated by CB1-Like Cannabinoid Receptors
1997
Differential Blockade of the Antinociceptive Effects of Centrally Administered Cannabinoids by SR141716A
1998
Cannabinoid CB1 receptor knockout mice fail to self-administer morphine but not other drugs of abuse
2001
Cannabinoid receptor agonist and antagonist effects on motor function in normal and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)-treated non-human primates
2001
Cannabinoid pharmacology in the cardiovascular system: potential protective mechanisms through lipid signalling
2004
CB1 cannabinoid receptor agonist WIN 55, 212-2 decreases intravenous cocaine self-administration in rats
1999
Pharmacological specificity of Δ9-tetrahydrocannabinol discrimination in rats
1995
3-(1′,1′-Dimethylbutyl)-1-deoxy-Δ8-THC and related compounds: synthesis of selective ligands for the CB2 receptor
1999
Cannabinoids and the immune system: Potential for the treatment of inflammatory diseases?
2005
International Union of Pharmacology. XXVII. Classification of Cannabinoid Receptors
2002 Standout
Hemodynamic effects of cannabinoids: coronary and cerebral vasodilation mediated by cannabinoid CB1 receptors
2001
Modulation of anxiety through blockade of anandamide hydrolysis
2002 Standout
Pathways and mechanisms of N-acylethanolamine biosynthesis: can anandamide be generated selectively?
2000
Effects of Guanine, Inosine, and Xanthine Nucleotides on β2-Adrenergic Receptor/GsInteractions: Evidence for Multiple Receptor Conformations
1999 StandoutNobel
Potentiation of the action of anandamide on hippocampal slices by the fatty acid amide hydrolase inhibitor, palmitylsulphonyl fluoride (AM 374)
1999
Pharmacological Actions of Cannabinoids
2005
Endocannabinoid signaling system and brain reward: Emphasis on dopamine
2005
Agonist‐inverse agonist characterization at CB1 and CB2 cannabinoid receptors of L759633, L759656 and AM630
1999
Interactions between synthetic vanilloids and the endogenous cannabinoid system
1998
Adverse Health Effects of Marijuana Use
2014 Standout
Drug Addiction, Dysregulation of Reward, and Allostasis
2001 Standout
Sativex successfully treats neuropathic pain characterised by allodynia: A randomised, double-blind, placebo-controlled clinical trial
2007
Descending control of pain
2002 Standout
The actions of some cannabinoid receptor ligands in the rat isolated mesenteric artery
1998
Endocannabinoid-Mediated Long-Term Plasticity Requires cAMP/PKA Signaling and RIM1α
2007 StandoutNobel
Involvement of central cannabinoid (CB 1 ) receptors in the establishment of place conditioning in rats
1998
Control of pain initiation by endogenous cannabinoids
1998 StandoutNature
Natural products: An evolving role in future drug discovery
2011 Standout
Pharmacophores for Ligand Recognition and Activation / Inactivation of the Cannabinoid Receptors
2003
Differential effects of cannabis extracts and pure plant cannabinoids on hippocampal neurones and glia
2006
Cardiovascular Pharmacology of Cannabinoids
2005
Molecular Characterization of a Phospholipase D Generating Anandamide and Its Congeners
2004 Standout
Effects of pharmacological manipulations of cannabinoid receptors on severity of dystonia in a genetic model of paroxysmal dyskinesia
2002
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
1999 StandoutNatureNobel
Molecular Neurobiology of The Cannabinoid Receptor
1996
Anandamide – the other side of the coin
2000 StandoutNobel
Pharmacological and biochemical interactions between opioids and cannabinoids
1999
Effects of cannabinoids and cannabinoid‐enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes
2010
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
Blood pressure regulation by endocannabinoids and their receptors
2005
Discovery and characterization of endogenous cannabinoids
1999
Cannabinoid Transmission and Reward-Related Events
1998
Estimating regression models with unknown break‐points
2003 Standout
Inhibition by cannabinoid receptor agonists of acetylcholine release from the guinea‐pig myenteric plexus
1997
The anandamide transport inhibitor AM404 activates vanilloid receptors
2000 StandoutNobel
Taming THC: potential cannabis synergy and phytocannabinoid‐terpenoid entourage effects
2011 Standout
Sex differences in antinociceptive and motoric effects of cannabinoids
2001
Effects of SR 141716A after acute or chronic cannabinoid administration in dogs
1998
The adolescent brain and age-related behavioral manifestations
2000 Standout
A tale of two cannabinoids: The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol
2005
Review article: endocannabinoids and their receptors in the enteric nervous system
2005
Dopamine activation of endogenous cannabinoid signaling in dorsal striatum
1999
(−)-Cannabidiol antagonizes cannabinoid receptor agonists and noradrenaline in the mouse vas deferens
2002
Effects of cannabinoid receptor agonists on neuronally‐evoked contractions of urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and human
2000
6ʺ-Azidohex-2ʺ-yne-cannabidiol: a potential neutral, competitive cannabinoid CB1 receptor antagonist
2004
Endocannabinoids as cardiovascular modulators
2000
The Stimulation of Ketogenesis by Cannabinoids in Cultured Astrocytes Defines Carnitine Palmitoyltransferase I as a New Ceramide‐Activated Enzyme
1999
Self-administration of the cannabinoid receptor agonist WIN 55,212-2 in drug-naive mice
1998
The actions of the cannabinoid receptor antagonist, SR 141716A, in the rat isolated mesenteric artery
1998
Gut microbiome and health: mechanistic insights
2022 Standout
Evidence of a novel site mediating anandamide‐induced negative inotropic and coronary vasodilatator responses in rat isolated hearts
2002
Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine
2002
Inhibitory effects of SR141716A on G-protein activation in rat brain
2001
Oral anti-inflammatory activity of cannabidiol, a non-psychoactive constituent of cannabis, in acute carrageenan-induced inflammation in the rat paw
2004
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
2006 Standout
Discriminative stimulus effects of anandamide in rats
1995
Pharmacological Characterization of Novel Water-Soluble Cannabinoids
2006
Unsaturated Long-Chain N-Acyl-vanillyl-amides (N-AVAMs): Vanilloid Receptor Ligands That Inhibit Anandamide-Facilitated Transport and Bind to CB1 Cannabinoid Receptors
1999 StandoutNobel
Natural products to drugs: natural product-derived compounds in clinical trials
2008 Standout
Δ9-Tetrahydrocannabinol impairs spatial memory through a cannabinoid receptor mechanism
1996
Evaluation of Cannabimimetic Discriminative Stimulus Effects of Anandamide and Methylated Fluoroanandamide in Rhesus Monkeys
1997
Behavioural and biochemical evidence for signs of abstinence in mice chronically treated with Δ‐9‐tetrahydrocannabinol
1998
Self-administration behavior is maintained by the psychoactive ingredient of marijuana in squirrel monkeys
2000
‘Endocannabinoids’ and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance
1998
Increased motivation for beer in rats following administration of a cannabinoid CB1 receptor agonist
1999
Δ9-Tetrahydrocannabinol, but not the endogenous cannabinoid receptor ligand anandamide, produces conditioned place avoidance
1998
Novelty and Anxiolytic Drugs Dissociate Two Components of Hippocampal Theta in Behaving Rats
2013 StandoutNobel
WIN 55,212-2 decreases the reinforcing actions of cocaine through CB1 cannabinoid receptor stimulation
2003
Characterization of Δ9-Tetrahydrocannabinol and Anandamide Antinociception in Nonarthritic and Arthritic Rats
1998
Conformational requirements for endocannabinoid interaction with the cannabinoid receptors, the anandamide transporter and fatty acid amidohydrolase
2000
Pharmacokinetics and Pharmacodynamics of Cannabinoids
2003
The Dopamine Hypothesis of Schizophrenia: Version III--The Final Common Pathway
2009 Standout
Evidence That 2-Arachidonoylglycerol but Not N-Palmitoylethanolamine or Anandamide Is the Physiological Ligand for the Cannabinoid CB2 Receptor
2000
Inhibitory effect of the cannabinoid receptor agonist WIN 55,212-2 on pentagastrin-induced gastric acid secretion in the anaesthetized rat
1999
Studies on the effects of anandamide in rat hepatic artery
1997
Cannabinoid receptors and pain
2001
Role of the Endogenous Cannabinoid System in the Regulation of Motor Activity
1998
Inhibition of GABAergic inhibitory postsynaptic currents by cannabinoids in rat corpus striatum
1998
Autoradiographic localization of dopamine D1 and D2 receptors in rat nucleus accumbens: Resistance to differential rearing conditions
1991 Standout
Analogues and homologues of N-palmitoylethanolamide, a putative endogenous CB2 cannabinoid, as potential ligands for the cannabinoid receptors
1999
Reversible Inhibitors of Fatty Acid Amide Hydrolase That Promote Analgesia: Evidence for an Unprecedented Combination of Potency and Selectivity
2004
Characterization of the Diarylether Sulfonylester (−)-(R)-3-(2-Hydroxymethylindanyl-4-oxy)phenyl-4,4,4-trifluoro-1-sulfonate (BAY 38-7271) as a Potent Cannabinoid Receptor Agonist with Neuroprotective Properties
2002
Δ9-Tetrahydrocannabinol-induced conditioned place preference and intracerebroventricular self-administration in rats
2004
A review of the published literature into cannabis withdrawal symptoms in human users
2002
The diverse CB1and CB2receptor pharmacology of three plant cannabinoids: Δ9‐tetrahydrocannabinol, cannabidiol and Δ9‐tetrahydrocannabivarin
2007 Standout
Mutational analysis and molecular modelling of the antagonist SR 144528 binding site on the human cannabinoid CB2 receptor
2000
Selective activation of cannabinoid CB2 receptors suppresses spinal fos protein expression and pain behavior in a rat model of inflammation
2003
Task specificity of cross-tolerance between Δ9-tetrahydrocannabinol and anandamide analogs in mice
2005
Behavioral effects of cannabinoids show differential sensitivity to cannabinoid receptor blockade and tolerance development
2004
Evidence for the presence of CB1 cannabinoid receptors on peripheral neurones and for the existence of neuronal non-CB1 cannabinoid receptors
1999
Cannabinoids: a real prospect for pain relief
2002
Self-administration of cannabinoids by experimental animals and human marijuana smokers
2005
Pharmacology of cannabinoid CB1 and CB2 receptors
1997
Evidence for a physiological role of endocannabinoids in the modulation of seizure threshold and severity
2002
Correlation between cannabinoid mediated effects on paired pulse depression and induction of long term potentiation in the rat hippocampal slice
1998
Effects on the Immune System
2005
Reduction of opioid dependence by the CB1 antagonist SR141716A in mice: evaluation of the interest in pharmacotherapy of opioid addiction
2001
Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects
2008 Standout
Biochemistry of the Endogenous Ligands of Cannabinoid Receptors
1998
Blockade of Effects of Smoked Marijuana by the CB1-Selective Cannabinoid Receptor Antagonist SR141716
2001
The molecular logic of endocannabinoid signalling
2003 Standout
Vasodilator actions of abnormal‐cannabidiol in rat isolated small mesenteric artery
2003
Cannabinoids in the treatment of glaucoma
2002
SR141716, a central cannabinoid (CB1) receptor antagonist, blocks the motivational and dopamine-releasing effects of nicotine in rats
2002
Analysis of the respiratory effects of cannabinoids in rats
2003
Cannabinoid receptors and their ligands
2002
Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review
2007 Standout
Antitumor Effects of Cannabidiol, a Nonpsychoactive Cannabinoid, on Human Glioma Cell Lines
2004
Evidence for the presence of CB2-like cannabinoid receptors on peripheral nerve terminals
1997
CB2 cannabinoid receptor-mediated peripheral antinociception
2001
Direct inhibition by cannabinoids of human 5‐HT3A receptors: probable involvement of an allosteric modulatory site
2002
Cannabinoids attenuate norepinephrine‐induced melatonin biosynthesis in the rat pineal gland by reducing arylalkylamine N‐acetyltransferase activity without involvement of cannabinoid receptors
2006
Cannabinoids excite dopamine neurons in the ventral tegmentum and substantia nigra
1997
Cannabinoids selectively inhibit proliferation and induce death of cultured human glioblastoma multiforme cells
2005
Cannabinoids inhibit excitatory neurotransmission in the substantia nigra pars reticulata
2000
Role of the highly conserved Asp‐Arg‐Tyr motif in signal transduction of the CB2 cannabinoid receptor
2000
Endocannabinoid system and opioid addiction: Behavioural aspects
2005
Cannabinoid modulation of dynorphin A: correlation to cannabinoid-induced antinociception
1999
Cannabinoid receptor ligands: clinical and neuropharmacological considerations, relevant to future drug discovery and development
2000
Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry
2014 StandoutNobel
Cannabidiol displays unexpectedly high potency as an antagonist of CB1and CB2receptor agonistsin vitro
2007
Neurocircuitry of Addiction
2009 Standout
Self-administration of ?9-tetrahydrocannabinol (THC) by drug naive squirrel monkeys
2003
Evidence for novel cannabinoid receptors
2005
Functional consequences of the acute administration of the cannabinoid receptor antagonist, SR141716A, in cannabinoid-naive and -tolerant animals: a quantitative 2-[14C]deoxyglucose study
2003
Cannabidiol-induced intracellular Ca2+ elevations in hippocampal cells
2005
N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor
2010
Neuropharmacology and therapeutic potential of cannabinoids
2000
Distinct Risk Factor Profiles for Human Papillomavirus Type 16–Positive and Human Papillomavirus Type 16–Negative Head and Neck Cancers
2008 Standout
Cannabinoids and neuroinflammation
2004
TRPV1 and TRPA1 Mediate Peripheral Nitric Oxide-Induced Nociception in Mice
2009 StandoutNobel
Cannabinoid Receptor Agonist Efficacy for Stimulating [35S]GTPγS Binding to Rat Cerebellar Membranes Correlates with Agonist-induced Decreases in GDP Affinity
1998
Cannabinoid and cannabinoid‐like receptors in microglia, astrocytes, and astrocytomas
2010
Uropathic Observations in Mice Expressing a Constitutively Active Point Mutation in the 5-HT3AReceptor Subunit
2004 StandoutNobel
The quest for a vascular endothelial cannabinoid receptor
2002
Therapeutic Potential of Cannabinoids in CNS Disease
2003
Synthesis and Characterization of Potent and Selective Agonists of the Neuronal Cannabinoid Receptor (CB1)
1999
Cannabis: pharmacology and toxicology in animals and humans
1996
REDUCTION OF VOLUNTARY ETHANOL INTAKE IN ETHANOL-PREFERRING sP RATS BY THE CANNABINOID ANTAGONIST SR-141716
1998
Cannabis: pharmacology and toxicology in animals and humans
1996
The Endocannabinoid System: Drug Targets, Lead Compounds, and Potential Therapeutic Applications
2005
Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB 1 Receptor Knockout Mice
1999 StandoutScience
In Vitro and in Vivo Pharmacological Characterization of JTE-907, a Novel Selective Ligand for Cannabinoid CB2 Receptor
2001
Synthesis of Pyridine and Dihydropyridine Derivatives by Regio- and Stereoselective Addition toN-Activated Pyridines
2012 Standout
G Protein-coupled Endothelial Receptor for Atypical Cannabinoid Ligands Modulates a Ca2+-dependent K+ Current
2003
Role of a Conserved Lysine Residue in the Peripheral Cannabinoid Receptor (CB2): Evidence for Subtype Specificity
1999
Intensely pleasurable responses to music correlate with activity in brain regions implicated in reward and emotion
2001 Standout
Mesenteric Vasodilation Mediated by Endothelial Anandamide Receptors
1999
Identification of a high-affinity binding site involved in the transport of endocannabinoids
2005
Structure-Activity Relationships of Indole- and Pyrrole-Derived Cannabinoids
1998
Cloning and Pharmacological Characterization of the Rat CB2 Cannabinoid Receptor
2000
Cannabinoid and Heroin Activation of Mesolimbic Dopamine Transmission by a Common µ 1 Opioid Receptor Mechanism
1997 Science
Antinociceptive Responses to Nicotinic Acetylcholine Receptor Ligands after Systemic and Intrathecal Administration in Mice
1998
A FAAH-Regulated Class of N-Acyl Taurines That Activates TRP Ion Channels
2006 StandoutNobel
Actions of Caffeine in the Brain with Special Reference to Factors That Contribute to Its Widespread Use
1999 Standout
The Concise Guide to PHARMACOLOGY 2013/14: G Protein‐Coupled Receptors
2013
Effects of Cannabinoids on Sympathetic and Parasympathetic Neuroeffector Transmission in the Rabbit Heart
2001
Cannabinoids in health and disease
2007
Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors
1999
Drug Abuse: Hedonic Homeostatic Dysregulation
1997 StandoutScience
Cannabinol Derivatives: Binding to Cannabinoid Receptors and Inhibition of Adenylylcyclase
1997
Worldwide contamination of food-crops with mycotoxins: Validity of the widely cited ‘FAO estimate’ of 25%
2019 Standout
HU-308: A specific agonist for CB 2 , a peripheral cannabinoid receptor
1999
Mechanism of the Hypotensive Action of Anandamide in Anesthetized Rats
1996
Novel Pyrazole Cannabinoids: Insights into CB1Receptor Recognition and Activation
2001
The Science of Marijuana
2007
Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors.
1997
Diversity Synthesis of N-Substituted 2-Amino-1,6-naphthyridine Derivatives under Microwave Irradiation
2009
Effects of Guanine, Inosine, and Xanthine Nucleotides on β2-Adrenergic Receptor/Gs Interactions: Evidence for Multiple Receptor Conformations
1999 StandoutNobel
Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning
2011 StandoutNobel
Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor.
2001
The cannabinoid system and immune modulation
2003
Presynaptically Located CB1 Cannabinoid Receptors Regulate GABA Release from Axon Terminals of Specific Hippocampal Interneurons
1999 Standout
Cannabinoids for Medical Use
2015 Standout
Mycotoxins co-contamination: Methodological aspects and biological relevance of combined toxicity studies
2016
Cannabinoids Protect Cells from Oxidative Cell Death: A Receptor-Independent Mechanism
2000
Microglial M1/M2 polarization and metabolic states
2015 Standout
The Third Transmembrane Helix of the Cannabinoid Receptor Plays a Role in the Selectivity of Aminoalkylindoles for CB2, Peripheral Cannabinoid Receptor
1999
Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: involvement of cytokine/chemokines and PMN
2003
Evidence for the efficacy and effectiveness of THC-CBD oromucosal spray in symptom management of patients with spasticity due to multiple sclerosis
2015
Nonpsychotropic Cannabinoid Receptors Regulate Microglial Cell Migration
2003
Cannabinoid receptors in microglia of the central nervous system: immune functional relevance
2005
Recent advances in the synthesis of nicotine and its derivatives
2007
Physiology of Microglia
2011 Standout
Metal-Free Multicomponent Syntheses of Pyridines
2014 Standout
Effects of cannabinoids on prefrontal neuronal responses to ventral tegmental area stimulation
2001
Cardiovascular Effects of Anandamide in Anesthetized and Conscious Normotensive and Hypertensive Rats
1997
Mutation of a Highly Conserved Aspartate Residue in the Second Transmembrane Domain of the Cannabinoid Receptors, CB1 and CB2, Disrupts G-Protein Coupling
1998
Works of BR Martin being referenced
Isobolographic characterization of drug interactions incorporating biological variability.
1990
Failure of Δ9-tetrahydrocannabinol and CP 55,940 to maintain intravenous self-administration under a fixed-interval schedule in rhesus monkeys
1994
Discriminative stimulus effects of CP 55,940 and structurally dissimilar cannabinoids in rats
1995
Evidence for separate neuronal mechanisms for the discriminative stimulus and catalepsy induced by Δ9-THC in the rat
1992
Interactions between THC and cannabidiol in mouse models of cannabinoid activity
2006
A cannabinoid with cardiovascular activity but no overt behavioral effects
1977
Tolerance to the discriminative stimulus effects of Delta(9)-tetrahydrocannabinol.
1993
Manipulation of the Tetrahydrocannabinol Side Chain Delineates Agonists, Partial Agonists, and Antagonists
1999
Pyrrolidine-modified and 6-substituted analogs of nicotine: A structure—affinity investigation
1996
Synthesis and pharmacology of (R)- and (5)-4′-hydroxy-Δ9-tetrahydrocannabinols
1997
Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands.
1996