Citation Impact

Citing Papers

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
2008 Standout
GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis
2019 Standout
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
Hematopoietic stem cell function in β-thalassemia is impaired and is rescued by targeting the bone marrow niche
2020
Cancer metabolism: fatty acid oxidation in the limelight
2013
Par3 cooperates with Sanpodo for the assembly of Notch clusters following asymmetric division of Drosophila sensory organ precursor cells
2021
EglN2 associates with the NRF 1‐ PGC 1α complex and controls mitochondrial function in breast cancer
2015 StandoutNobel
Hypoxia‐inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype
2016 StandoutNobel
Classical and Alternative End-Joining Pathways for Repair of Lymphocyte-Specific and General DNA Double-Strand Breaks
2012
The Role of Replication-Associated Repair Factors on R-Loops
2017
DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity
2018 StandoutNobel
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
Hematopoietic chimerism and donor-specific skin allograft tolerance after non-genotoxic CD117 antibody-drug-conjugate conditioning in MHC-mismatched allotransplantation
2019
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Hif-2α is not essential for cell-autonomous hematopoietic stem cell maintenance
2013 StandoutNobel
Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells
2012
Regulation and function of mTOR signalling in T cell fate decisions
2012
Phosphorylation of ETS1 by Src Family Kinases Prevents Its Recognition by the COP1 Tumor Suppressor
2014 StandoutNobel
FOXO transcription factors: key regulators of cellular quality control
2014
Mechanism and medical implications of mammalian autophagy
2018 Standout
Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis
2012 Nature
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Therapeutic targeting of splicing in cancer
2016
Loss of miR-10a Activates Lpo and Collaborates with Activated Wnt Signaling in Inducing Intestinal Neoplasia in Female Mice
2013
Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
2011 StandoutNobel
Hallmarks of aging: An expanding universe
2023 Standout
RNA sequencing: advances, challenges and opportunities
2010
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Signal Transduction by Mitochondrial Oxidants
2011
Modulation of oxidative stress as an anticancer strategy
2013 Standout
Targeting the hepcidin–ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation
2011
The bone marrow at the crossroads of blood and immunity
2011
Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells
2010 Nature
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades
2011 Standout
FOXOs: signalling integrators for homeostasis maintenance
2013
Metazoan MicroRNAs
2018 Standout
Spotlight on the role of COP1 in tumorigenesis
2012
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells
2010 Nature
Disruption of Fnip1 Reveals a Metabolic Checkpoint Controlling B Lymphocyte Development
2012 StandoutNobel
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Iron regulation by hepcidin
2013
Integrating Physiological Regulation with Stem Cell and Tissue Homeostasis
2011
miR-10a is aberrantly overexpressed in Nucleophosmin1 mutated acute myeloid leukaemia and its suppression induces cell death
2012
PI3 Kinase and FOXO1 Transcription Factor Activity Differentially Control B Cells in the Germinal Center Light and Dark Zones
2015
Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets
2007
Autophagy and Aging
2011 Standout
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
2013 Standout
Adipose Tissue Macrophages Promote Myelopoiesis and Monocytosis in Obesity
2014
Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood
2010
Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
2013 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells
2013
Matrix-Embedded Osteocytes Regulate Mobilization of Hematopoietic Stem/Progenitor Cells
2013
The PI3K Pathway in Human Disease
2017 Standout
Inflammasomes: mechanism of action, role in disease, and therapeutics
2015 Standout
DAF-16/FOXO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage
2014
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2
2016 StandoutNobel
BCL2 Is a Downstream Effector of MIZ-1 Essential for Blocking c-MYC-induced Apoptosis
2006
Anemia of Chronic Disease
2005 Standout
A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance
2012
Safe and Effective In Vivo Targeting and Gene Editing in Hematopoietic Stem Cells: Strategies for Accelerating Development
2021 StandoutNobel
Metabolic Regulation of Redox Status in Stem Cells
2014
Metabolic switching and fuel choice during T‐cell differentiation and memory development
2012
Serine Synthesis Helps Hypoxic Cancer Stem Cells Regulate Redox
2016 StandoutNobel
Differentiation of CD8 memory T cells depends on Foxo1
2013
Clinical iron deficiency disturbs normal human responses to hypoxia
2016 StandoutNobel
PDGFRα and CD51 mark human Nestin+ sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion
2013
Plasticity in the lung: making and breaking cell identity
2017
Defining Adult Stem Cells by Function, not by Phenotype
2018
Iron and hepcidin: a story of recycling and balance
2013
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Therapeutically relevant engraftment of a CRISPR-Cas9–edited HSC-enriched population with HbF reactivation in nonhuman primates
2019
Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation
2012 Standout
The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish
2011
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition
2014
Adult hematopoietic stem cells lacking Hif-1α self-renew normally
2016 StandoutNobel
Ferroptosis as a target for protection against cardiomyopathy
2019 Standout
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Iron-Deficiency Anemia
2015 Standout
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
Systemic Iron Homeostasis
2013
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Multiple Myeloma
2011 Standout
The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance
2011
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Specific Turn-On Fluorescent Probe with Aggregation-Induced Emission Characteristics for SIRT1 Modulator Screening and Living-Cell Imaging
2015
Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats
2011
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
2016 StandoutNobel

Works of Borja Sáez being referenced

Down-Regulation of hsa-miR-10a in Chronic Myeloid Leukemia CD34+ Cells Increases USF2-Mediated Cell Growth
2008
SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β‐catenin
2013
Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
2017
Parent stem cells can serve as niches for their daughter cells
2015 Nature
The Lkb1 metabolic sensor maintains haematopoietic stem cell survival
2010 Nature
Injury Induces Direct Lineage Segregation of Functionally Distinct Airway Basal Stem/Progenitor Cell Subpopulations
2015
Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation
2019
Amplification of IGH/MYC fusion in clinically aggressive IGH/BCL2‐positive germinal center B‐cell lymphomas
2005
AKT/FOXO Signaling Enforces Reversible Differentiation Blockade in Myeloid Leukemias
2011
Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin
2016
Identification of overexpressed genes in frequently gained/amplified chromosome regions in multiple myeloma.
2006
Preclinical Activity of Splicing Modulators in U2AF1 Mutant MDS/AML
2015
Specific bone cells produce DLL4 to generate thymus-seeding progenitors from bone marrow
2015
Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation
2011
Diabetes Impairs Hematopoietic Stem Cell Mobilization by Altering Niche Function
2011
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