Citation Impact
Citing Papers
Argonaute2 Is the Catalytic Engine of Mammalian RNAi
2004 StandoutScience
Multiplex Genome Engineering Using CRISPR/Cas Systems
2013 StandoutScience
Widespread Translational Inhibition by Plant miRNAs and siRNAs
2008 Science
C3PO, an Endoribonuclease That Promotes RNAi by Facilitating RISC Activation
2009 Science
Programmable RNA recognition using a CRISPR-associated Argonaute
2018 StandoutNobel
A Distinct Small RNA Pathway Silences Selfish Genetic Elements in the Germline
2006 Science
Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons
2020 StandoutNobel
Functional Genomic Analysis of RNA Interference in C. elegans
2005 StandoutScienceNobel
A drug-controllable tag for visualizing newly synthesized proteins in cells and whole animals
2008 StandoutNobel
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
2012 StandoutScienceNobel
MicroRNAs Regulate Brain Morphogenesis in Zebrafish
2005 Science
Transposition-Driven Genomic Heterogeneity in the Drosophila Brain
2013 StandoutScienceNobel
Distinct Populations of Primary and Secondary Effectors During RNAi in C. elegans
2006 StandoutScienceNobel
Crystal Structure of Argonaute and Its Implications for RISC Slicer Activity
2004 Science
Three-dimensional tracking of single mRNA particles in Saccharomyces cerevisiae using a double-helix point spread function
2010 StandoutNobel
Recapitulation of Short RNA-Directed Translational Gene Silencing In Vitro
2006
PIWI-interacting small RNAs: the vanguard of genome defence
2011
Piwi and piRNAs Act Upstream of an Endogenous siRNA Pathway to Suppress Tc3 Transposon Mobility in the Caenorhabditis elegans Germline
2008
Normal microRNA Maturation and Germ-Line Stem Cell Maintenance Requires Loquacious, a Double-Stranded RNA-Binding Domain Protein
2005
A direct role for Hsp90 in pre-RISC formation in Drosophila
2010
Collapse of Germline piRNAs in the Absence of Argonaute3 Reveals Somatic piRNAs in Flies
2009
RNA Helicase A Interacts with RISC in Human Cells and Functions in RISC Loading
2007
A human, ATP-independent, RISC assembly machine fueled by pre-miRNA
2005
Dicer is dispensable for asymmetric RISC loading in mammals
2011
A Coordinated Local Translational Control Point at the Synapse Involving Relief from Silencing and MOV10 Degradation
2009
Short Interfering RNA Strand Selection Is Independent of dsRNA Processing Polarity during RNAi in Drosophila
2006
Human Argonaute2 Mediates RNA Cleavage Targeted by miRNAs and siRNAs
2004 Standout
The HP1 Homolog Rhino Anchors a Nuclear Complex that Suppresses piRNA Precursor Splicing
2014
Sorting of Drosophila Small Silencing RNAs
2007
MUT-14 and SMUT-1 DEAD Box RNA Helicases Have Overlapping Roles in Germline RNAi and Endogenous siRNA Formation
2014 StandoutNobel
Recognition of the pre-miRNA structure by Drosophila Dicer-1
2011
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Regulation of microRNA biogenesis
2014 Standout
Small non-coding RNAs in animal development
2008
Drosophila microRNAs Are Sorted into Functionally Distinct Argonaute Complexes after Production by Dicer-1
2007
Passenger-Strand Cleavage Facilitates Assembly of siRNA into Ago2-Containing RNAi Enzyme Complexes
2005
Identification of small RNA pathway genes using patterns of phylogenetic conservation and divergence
2012 StandoutNatureNobel
nhl-2 Modulates MicroRNA Activity in Caenorhabditis elegans
2009 StandoutNobel
Precursor MicroRNA-Programmed Silencing Complex Assembly Pathways in Mammals
2012
RNAi: The Nuts and Bolts of the RISC Machine
2005
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
Kinetic analysis of the RNAi enzyme complex
2004
Synaptic Protein Synthesis Associated with Memory Is Regulated by the RISC Pathway in Drosophila
2006
Stalled Spliceosomes Are a Signal for RNAi-Mediated Genome Defense
2013
Small silencing RNAs: an expanding universe
2009 Standout
Slicer function of Drosophila Argonautes and its involvement in RISC formation
2005
Hsc70/Hsp90 Chaperone Machinery Mediates ATP-Dependent RISC Loading of Small RNA Duplexes
2010
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
2005 StandoutNature
Molecular motors
2003 Nature
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
2011 StandoutNatureNobel
Structural determinants of miRNAs for RISC loading and slicer-independent unwinding
2009
MicroRNAs: Target Recognition and Regulatory Functions
2009 Standout
A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants
2009 StandoutNatureNobel
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
A single Argonaute protein mediates both transcriptional and posttranscriptional silencing in Schizosaccharomyces pombe
2004
Single mRNA Molecules Demonstrate Probabilistic Movement in Living Mammalian Cells
2003
Crystal structure of a PIWI protein suggests mechanisms for siRNA recognition and slicer activity
2004
Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway
2009
Analysis of the C. elegans Argonaute Family Reveals that Distinct Argonautes Act Sequentially during RNAi
2006 StandoutNobel
Argonaute proteins: functional insights and emerging roles
2013
In Vitro Assembly of Plant RNA-Induced Silencing Complexes Facilitated by Molecular Chaperone HSP90
2010
Making RISC
2010
Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7
2008 StandoutNatureNobel
The surveillance of pre-mRNA splicing is an early step in C. elegans RNAi of endogenous genes
2018 StandoutNobel
Dicer Partner Proteins Tune the Length of Mature miRNAs in Flies and Mammals
2012
Argonaute proteins: key players in RNA silencing
2007
The widespread regulation of microRNA biogenesis, function and decay
2010 Standout
Conversion of pre-RISC to holo-RISC by Ago2 during assembly of RNAi complexes
2006
Purified Argonaute2 and an siRNA form recombinant human RISC
2005
The MicroRNA miR-1 Regulates a MEF-2-Dependent Retrograde Signal at Neuromuscular Junctions
2008 StandoutNobel
Defining fundamental steps in the assembly of the Drosophila RNAi enzyme complex
2015 Nature
RNA-guided genetic silencing systems in bacteria and archaea
2012 StandoutNatureNobel
Electrically driven directional motion of a four-wheeled molecule on a metal surface
2011 StandoutNatureNobel
Small RNA-Mediated Quiescence of Transposable Elements in Animals
2010
Gene silencing mechanisms mediated by Aubergine–piRNA complexes in Drosophila male gonad
2007
Sorting of Small RNAs into Arabidopsis Argonaute Complexes Is Directed by the 5′ Terminal Nucleotide
2008
In Vivo Imaging of oskar mRNA Transport Reveals the Mechanism of Posterior Localization
2008
Moloney Leukemia Virus 10 (MOV10) Protein Inhibits Retrovirus Replication
2010
Structural basis for 5′-end-specific recognition of guide RNA by the A. fulgidus Piwi protein
2005 Nature
Maternal piRNAs Are Essential for Germline Development following De Novo Establishment of Endo-siRNAs in Caenorhabditis elegans
2015
Small RNAs as Guardians of the Genome
2009
siRNA Repositioning for Guide Strand Selection by Human Dicer Complexes
2011 StandoutNobel
Biology of PIWI-interacting RNAs: new insights into biogenesis and function inside and outside of germlines
2012
The RNA-Induced Silencing Complex Is a Mg2+-Dependent Endonuclease
2004
ATP-dependent human RISC assembly pathways
2009
Structure of C3PO and mechanism of human RISC activation
2011
Dicer-2 and R2D2 coordinately bind siRNA to promote assembly of the siRISC complexes
2006
Dicer-1, but not Loquacious, is critical for assembly of miRNA-induced silencing complexes
2007
Mechanisms of gene silencing by double-stranded RNA
2004 StandoutNature
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways
2004
MOV10 RNA Helicase Is a Potent Inhibitor of Retrotransposition in Cells
2012
Perspective: machines for RNAi
2005
Argonaute2 Cleaves the Anti-Guide Strand of siRNA during RISC Activation
2005
Single Processing Center Models for Human Dicer and Bacterial RNase III
2004
The role of PACT in the RNA silencing pathway
2006
Identification of Novel Argonaute-Associated Proteins
2005
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
Cleavage of the siRNA passenger strand during RISC assembly in human cells
2006
Carboxy-terminal domain of AID required for its mRNA complex formation in vivo
2009 StandoutNobel
The Piwi-piRNA Pathway Provides an Adaptive Defense in the Transposon Arms Race
2007 Science
Hsp90 Regulates the Function of Argonaute 2 and Its Recruitment to Stress Granules and P-Bodies
2009
New perspectives on the diversification of theRNA interference system: insights from comparative genomics and smallRNA sequencing
2013
A Cas9–guide RNA complex preorganized for target DNA recognition
2015 StandoutScienceNobel
Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal
2015 StandoutNobel
MOV10 Provides Antiviral Activity against RNA Viruses by Enhancing RIG-I–MAVS-Independent IFN Induction
2016
Association of the Herpes Simplex Virus Type 1 Us11 Gene Product with the Cellular Kinesin Light-Chain-Related Protein PAT1 Results in the Redistribution of Both Polypeptides
2003
ATP-independent diffusion of double-stranded RNA binding proteins
2012 StandoutNobel
A bacterial Argonaute with noncanonical guide RNA specificity
2016 StandoutNobel
In vitro reconstitution of the human RISC-loading complex
2008 StandoutNobel
RNAi-mediated immunity provides strong protection against the negative-strand RNA vesicular stomatitis virus in Drosophila
2010 StandoutNobel
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
RNAi is an antiviral immune response against a dsRNA virus in Drosophila melanogaster
2006
A Protein Sensor for siRNA Asymmetry
2004 Science
A Molecular Elevator
2004 StandoutScienceNobel
Structural Basis for Double-Stranded RNA Processing by Dicer
2006 StandoutScienceNobel
Virus Counterdefense: Diverse Strategies for Evading the RNA-Silencing Immunity
2006
TheflamencoLocus Controls thegypsyandZAMRetroviruses and Is Required for Drosophila Oogenesis
2007
The neuronal microRNA system
2006
microRNA Functions
2007 Standout
Biogenesis and germline functions of piRNAs
2007
E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes
2020 StandoutNobel
mut-16 and other mutator class genes modulate 22G and 26G siRNA pathways in Caenorhabditis elegans
2011 StandoutNobel
The growing catalog of small RNAs and their association with distinct Argonaute/Piwi family members
2008
Antiviral Protein APOBEC3G Localizes to Ribonucleoprotein Complexes Found in P Bodies and Stress Granules
2006
Immunopurification of Ago1 miRNPs selects for a distinct class of microRNA targets
2009 StandoutNobel
The ERI-6/7 Helicase Acts at the First Stage of an siRNA Amplification Pathway That Targets Recent Gene Duplications
2011 StandoutNobel
Works of Birgit S. Koppetsch being referenced
UAP56 Couples piRNA Clusters to the Perinuclear Transposon Silencing Machinery
2012
The Drosophila HP1 Homolog Rhino Is Required for Transposon Silencing and piRNA Production by Dual-Strand Clusters
2009
rasiRNAs, DNA Damage, and Embryonic Axis Specification
2006
Heterotypic piRNA Ping-Pong Requires Qin, a Protein with Both E3 Ligase and Tudor Domains
2011
Kinesin I-dependent cortical exclusion restricts pole plasm to the oocyte posterior
2002
Adaptation to P Element Transposon Invasion in Drosophila melanogaster
2011
RISC Assembly Defects in the Drosophila RNAi Mutant armitage
2004
Drosophila rasiRNA Pathway Mutations Disrupt Embryonic Axis Specification through Activation of an ATR/Chk2 DNA Damage Response
2007
The Drosophila SDE3 Homolog armitage Is Required for oskar mRNA Silencing and Embryonic Axis Specification
2004
In Vivo Analysis of Drosophila bicoid mRNA Localization Reveals a Novel Microtubule-Dependent Axis Specification Pathway
2001