Citation Impact

Citing Papers

Reconstituting Organ-Level Lung Functions on a Chip
2010 StandoutScience
Myofibroblasts and mechano-regulation of connective tissue remodelling
2002 Standout
Monocyte Chemotactic Protein–1 As A Chemoattractant for Human Hepatic Stellate Cells
1999
Characterization of Insulin-Like Growth Factor (IGF)-I-Receptor Binding Sites during In Vitro Transformation of Rat Hepatic Stellate Cells to Myofibroblasts
1996
Formation and Function of the Myofibroblast during Tissue Repair
2007 Standout
Xylosyltransferase II is the predominant isoenzyme which is responsible for the steady-state level of xylosyltransferase activity in human serum
2015 StandoutNobel
Analysis of the expression pattern of the latent transforming growth factor β binding protein isoforms in normal and diseased human liver reveals a new splice variant missing the proteinase-sensitive hinge region
1998
Liver fibrosis
2005 Standout
Liver fibrosis
2000
Inhibition of Apoptosis of Activated Hepatic Stellate Cells by Tissue Inhibitor of Metalloproteinase-1 Is Mediated via Effects on Matrix Metalloproteinase Inhibition
2002
The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis
2005
Up-regulated expression of the receptor for advanced glycation end products in cultured rat hepatic stellate cells during transdifferentiation to myofibroblasts
2001
Superoxide-induced apoptosis of activated rat hepatic stellate cells
2004
Increased serum xylosyltransferase activity in patients with liver fibrosis
2009
The Cellular Basis of Hepatic Fibrosis -- Mechanisms and Treatment Strategies
1993
Impact of oestrogens on the progression of liver disease
2003
Emerging insights into Transforming growth factor   Smad signal in hepatic fibrogenesis
2007
Isoforms and splice variant of transforming growth factor β–binding protein in rat hepatic stellate cells
1998
Cell-matrix and cell-cell contacts of myofibroblasts: role in connective tissue remodeling
2003
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Suppressive effects of 17β-estradiol on hepatic fibrosis in CCl4-induced rat model
2004
Antifibrotic Agents for Liver Disease
2005
CD133+ hepatic stellate cells are progenitor cells
2006
Liver fibrosis – from bench to bedside
2003 Standout
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Expression of Interleukin-10 by in Vitro and in Vivo Activated Hepatic Stellate Cells
1998
Differential regulation of TGF-β signal in hepatic stellate cells between acute and chronic rat liver injury
2002
Normal rat hepatic stellate cells respond to endotoxin in LBP‐independent manner to produce inhibitor(s) of DNA synthesis in hepatocytes
2005
TGF-β signaling in tumor suppression and cancer progression
2001 Standout
Pulmonary fibrosis: pathogenesis, etiology and regulation
2009 Standout
TLR4 enhances TGF-β signaling and hepatic fibrosis
2007 Standout
Lactate adversely affects the in vitro formation of endothelial cell tubular structures through the action of TGF-β1
2007
Transformation-dependent calcium influx by voltage-operated calcium channels in stellate cells of rat liver
1999
Parallel epigenetic and genetic changes in the pathogenesis of hepatitis virus-associated hepatocellular carcinoma
2005
Ncf1 (p47phox) Is Essential for Direct Regulatory T Cell Mediated Suppression of CD4+ Effector T Cells
2011
Constitutive phosphorylation and nuclear localization of Smad3 are correlated with increased collagen gene transcription in activated hepatic stellate cells
2001
Non-parenchymal cell responses in paracetamol (acetaminophen)-induced liver injury
1994
The biology and function of fibroblasts in cancer
2016 Standout
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
Interleukin–10 Controls Neutrophilic Infiltration, Hepatocyte Proliferation, and Liver Fibrosis Induced by Carbon Tetrachloride in Mice
1998
HCVpro: Hepatitis C virus protein interaction database
2011
Therapeutic strategies against TGF‐β signaling pathway in hepatic fibrosis
2005
LPS-mediated NFκB activation varies between activated human hepatic stellate cells from different donors
2004
Reduced liver fibrosis in hypoxia-inducible factor-1α-deficient mice
2009
The Role of Smad3 in Mediating Mouse Hepatic Stellate Cell Activation
2001
Platelet-derived growth factor isoform expression in carbon tetrachloride-induced chronic liver injury
2008
Insights into the Pathobiology of Hepatitis C Virus-Associated Cirrhosis
2002
Y-box Protein-1 Is the Crucial Mediator of Antifibrotic Interferon-γ Effects
2005
Cryopreservation of hepatic stellate cells
2005
Hepatic tumor–stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge
2009
Synergism between hepatocytes and Kupffer cells in the activation of fat storing cells (perisinusoidal lipocytes)
1993
New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer
2018 Standout
Smad2 and Smad4 gene mutations in hepatocellular carcinoma
1999
Suppression of type I collagen production by microRNA-29b in cultured human stellate cells
2009
Reversal of Fibrosis: No Longer a Pipe Dream?
2006
Expression of Smads during in Vitro Transdifferentiation of Hepatic Stellate Cells to Myofibroblasts
2001
Liver fibrosis: Insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors
2003
Nonresolving Inflammation
2010 Standout
Hepatic stellate cells and the regulation of liver inflammation
1999
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Fibrogenic effect of oxidative stress on rat hepatic stellate cells
1998
Apoptotic body engulfment by hepatic stellate cells promotes their survival by the JAK/STAT and Akt/NF-κB-dependent pathways
2009
The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)
2016 Standout
Profibrogenic transforming growth factor-β/activin receptor–like kinase 5 signaling via connective tissue growth factor expression in hepatocytes
2007
The cell biology of liver fibrogenesis - an imbalance of proliferation, growth arrest and apoptosis of myofibroblasts
1998
A Role for Serotonin (5-HT) in Hepatic Stellate Cell Function and Liver Fibrosis
2006
Is liver fibrosis reversible?
2000
Caspase 9–dependent killing of hepatic stellate cells by activated Kupffer cells
2002
Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
2007 Standout
Antisense strategy against PDGF B-chain proves effective in preventing experimental liver fibrogenesis
2004
Abrogation of Transforming Growth Factor-β Signaling by SMAD7 Inhibits Collagen Gel Contraction of Human Dermal Fibroblasts
2005
Molecular Regulation of Hepatic Fibrosis, an Integrated Cellular Response to Tissue Injury
2000 Standout
Connective tissue growth factor, steatosis and fibrosis in patients with chronic hepatitis C
2007
Mechanisms of Hepatic Fibrogenesis
2008 Standout
Human hepatic stellate cells show features of antigen-presenting cells and stimulate lymphocyte proliferation
2003
Diabetes and Atherosclerosis
2002 Standout
Hepatic stellate cell immunodetection and cirrhotic evolution of viral hepatitis in liver allografts
1997
Autocrine release of TGF‐β by portal fibroblasts regulates cell growth
2004
Mechanisms and Therapy of Hepatic Fibrosis: Report of the Aasld Single Topic Basic Research Conference
2000
Smad7 prevents activation of hepatic stellate cells and liver fibrosis in rats
2003
Pharmacological aspects of pentoxifylline with emphasis on its inhibitory actions on hepatic fibrogenesis
1997
Hepatocyte Transplantation Activates Hepatic Stellate Cells With Beneficial Modulation of Cell Engraftment in the Rat *
2005
Biological Gene Delivery Vehicles: Beyond Viral Vectors
2009
Systemic sclerosis: a prototypic multisystem fibrotic disorder
2007 Standout
Activated stellate cells express the TRAIL receptor-2/death receptor-5 and undergo TRAIL-mediated apoptosis
2003
IFN-γ abrogates profibrogenic TGF-β signaling in liver by targeting expression of inhibitory and receptor Smads
2006
Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
2008 Standout
Expression of activation-induced cytidine deaminase in human hepatocytes via NF-κB signaling
2007 StandoutNobel
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
EMT: 2016
2016 Standout
Molecular regulation of vessel maturation
2003 Standout
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
2012 Standout
Decreased susceptibility to Fas-induced apoptosis of systemic sclerosis dermal fibroblasts
2001
Malondialdehyde–acetaldehyde–protein adducts increase secretion of chemokines by rat hepatic stellate cells
2001
Expression and location of Smad2, 4 mRNAs during and after liver fibrogenesis of rats
2006
PPARγ signaling and metabolism: the good, the bad and the future
2013 Standout
Alternative Activation of Macrophages: Mechanism and Functions
2010 Standout
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
Id1 is a critical mediator in TGF-β–induced transdifferentiation of rat hepatic stellate cells
2006
The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis
1999
Toxicity of hepatotoxins: new insights into mechanisms and therapy
1999
Oxidative stress, KLF6 and transforming growth factor-β up-regulation differentiate non-alcoholic steatohepatitis progressing to fibrosis from uncomplicated steatosis in rats
2003
Toll–Like Receptor 4 Mediates Inflammatory Signaling by Bacterial Lipopolysaccharide in Human Hepatic Stellate Cells
2003
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
Induction of Gas6 protein in CCl4-induced rat liver injury and anti-apoptotic effect on hepatic stellate cells
2006
Rosiglitazone prevents nutritional fibrosis and steatohepatitis in mice
2008
Mechanisms of force generation and transmission by myofibroblasts
2003
Sequential changes in human Ito cells and their relation to postnecrotic liver fibrosis in massive and submassive hepatic necrosis
1995
Corticosteroids stimulate selectively transforming growth factor (TGF)-β receptor type III expression in transdifferentiating hepatic stellate cells
2003
Smads 2 and 3 Are Differentially Activated by Transforming Growth Factor-β (TGF-β) in Quiescent and Activated Hepatic Stellate Cells
2003
Replicative Senescence of Activated Human Hepatic Stellate Cells Is Accompanied by A Pronounced Inflammatory But Less Fibrogenic Phenotype
2003
Advanced glycation end products induce production of reactive oxygen species via the activation of NADPH oxidase in murine hepatic stellate cells
2009
Biomarkers for epithelial-mesenchymal transitions
2009 Standout
Fibroblasts in cancer
2006 Standout
Somatostatin inhibits pro‐inflammatory cytokine secretion from rat hepatic stellate cells
2005
Expression and Regulation of Cell Adhesion Molecules by Hepatic Stellate Cells (HSC) of Rat Liver
1999
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
2011 Standout
Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis
2006
Sustained Activation of Fibroblast Transforming Growth Factor-β/Smad Signaling in a Murine Model of Scleroderma
2003
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Variable expression of cystatin C in cultured trans-differentiating rat hepatic stellate cells
2006
Roles of TGF-beta in hepatic fibrosis
2002
Chapter 11 Proteinase families and their inhibitors
2001
Chronic liver injury, TGF-β, and cancer
2001
Towards a human-on-chip: Culturing multiple cell types on a chip with compartmentalized microenvironments
2009
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Stellate cell apoptosis by a soluble mediator from immortalized human hepatocytes
2006
New functions for the matrix metalloproteinases in cancer progression
2002 Standout
Hepatic Stellate Cells Express the Low Affinity Nerve Growth Factor Receptor p75 and Undergo Apoptosis in Response to Nerve Growth Factor Stimulation
2000
Molecular regulation of hepatic fibrogenesis
1998
Aldehydes potentiate α2(I) collagen gene activity by JNK in hepatic stellate cells
2001
N‐Acetyl‐L‐Cysteine abrogates fibrogenic properties of fibroblasts isolated from Dupuytren's disease by blunting TGF‐β signalling
2006
CCR1 and CCR5 promote hepatic fibrosis in mice
2009
Exposure to bacterial cell wall products triggers an inflammatory phenotype in hepatic stellate cells
2005
Hepatoprotective Effect of Infliximab, an Anti-TNF-α Agent, on Carbon Tetrachloride-Induced Hepatic Fibrosis
2008
Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts
2003
Chemokines in liver inflammation and fibrosis
2002
Inhibitory effects of microRNA 19b in hepatic stellate cell-mediated fibrogenesis
2012
Growth Inhibition and Apoptosis in Liver Myofibroblasts Promoted by Hepatocyte Growth Factor Leads to Resolution from Liver Cirrhosis
2005
Apoptosis of hepatic stellate cells: involvement in resolution of biliary fibrosis and regulation by soluble growth factors
2001
Human hepatic stellate cells express CCR5 and RANTES to induce proliferation and migration
2003
CD95/CD95L-mediated apoptosis of the hepatic stellate cell. A mechanism terminating uncontrolled hepatic stellate cell proliferation during hepatic tissue repair.
1997
IL-13 Induces Connective Tissue Growth Factor in Rat Hepatic Stellate Cells via TGF-β–Independent Smad Signaling
2011
Smad2 and Smad3 Play Different Roles in Rat Hepatic Stellate Cell Function and α-Smooth Muscle Actin Organization
2005
Global gene expression of cells attached to a tissue engineering scaffold
2004 StandoutNobel
Myofibroblasts. I. Paracrine cells important in health and disease
1999
Rat hepatic stellate cells produce cytokine-induced neutrophil chemoattractant in culture and in vivo
1998
Oncogenic RAS pathway activation promotes resistance to anti-VEGF therapy through G-CSF–induced neutrophil recruitment
2013
Immune-Mediated Inhibition of Metastases after Treatment with Local Radiation and CTLA-4 Blockade in a Mouse Model of Breast Cancer
2005 StandoutNobel
The Calpain System
2003 Standout
Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
2007 Standout
Liver fibrosis
1999
Retinoic acid suppresses the response to platelet-derived growth factor in human hepatic Ito-cell-like myofibroblasts: a post-receptor mechanism independent of raf/fos/jun/egr activation
1993
A water-soluble tetrazolium salt useful for colorimetric cell viability assay
1999
Stellate cells: A moving target in hepatic fibrogenesis†
2004
Wound Healing: A Cellular Perspective
2018 Standout
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Human Hepatic Stellate Cells Show Features of Antigen–Presenting Cells and Stimulate Lymphocyte Proliferation
2003
Superoxide Ion: Generation and Chemical Implications
2016 Standout
Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases
2003 Standout
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis
2008 Standout
V. TGF-β signaling pathways
2000
Internal Disequilibria and Phenotypic Diversification during Replication of Hepatitis C Virus in a Noncoevolving Cellular Environment
2017 StandoutNobel
Prostaglandin F2α and D2 Release From Primary Ito Cell Cultures After Stimulation With Noradrenaline and Atp But Not Adenosine
1994
Role of Transcriptional Factors in Stellate Cell Activation
1999
Molecular mechanisms of ionizing radiation‐induced apoptosis
1999
Novel CXCR2‐dependent liver regenerative qualities of ELR‐containing CXC chemokines
1999
Activation of matrix metalloproteinase-2 from hepatic stellate cells requires interactions with hepatocytes.
1997
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
HEPATIC FIBROSIS: Molecular Mechanisms and Drug Targets
2004
Current status of novel antifibrotic therapies in patients with chronic liver disease
2011
Suppression of okadaic acid‐induced apoptosis by overexpression of calpastatin in human UVr‐1 cells
1999
Transforming Growth Factor-β as a Therapeutic Target in Hepatocellular Carcinoma
2014
Transforming growth factor-β1 downregulation of Smad1 gene expression in rat hepatic stellate cells
2003
Insulin-Like Growth Factors Stimulate Expression of Hepatocyte Growth Factor But Not Transforming Growth Factor β1 in Cultured Hepatic Stellate Cells*
1997

Works of Birgit Lahme being referenced

Induction of neutrophil-attracting chemokines in transforming rat hepatic stellate cells
1997
Validation of connective tissue growth factor (CTGF/CCN2) and its gene polymorphisms as noninvasive biomarkers for the assessment of liver fibrosis
2009
Intracrine signalling of activin A in hepatocytes upregulates connective tissue growth factor (CTGF/CCN2) expression
2008
Expression of isoforms and splice variants of the latent transforming growth factor β binding protein (LTBP) in cultured human liver myofibroblasts
2001
Pharmacological application of caffeine inhibits TGF-β-stimulated connective tissue growth factor expression in hepatocytes via PPARγ and SMAD2/3-dependent pathways
2008
Differential expression of monocyte chemotactic protein-1 (MCP-1) in transforming rat hepatic stellate cells
1999
Expression and Matrix Deposition of Latent Transforming Growth Factor β Binding Proteins in Normal and Fibrotic Rat Liver and Transdifferentiating Hepatic Stellate Cells in Culture
2001
Transformation-dependent susceptibility of rat hepatic stellate cells to apoptosis induced by soluble fas ligand
1998
Loss of TGF-β dependent growth control during HSC transdifferentiation
2007
Elevation of Nε-(carboxymethyl)lysine-modified advanced glycation end products in chronic liver disease is an indicator of liver cirrhosis
2005
Attenuation of TGF-β-Induced Apoptosis in Primary Cultures of Hepatocytes by Calpain Inhibitors
1997
Induction of rat liver parenchymal cell apoptosis by hepatic myofibroblasts via transforming growth factor β
1996
Modulation of transforming growth factor β response and signaling during transdifferentiation of rat hepatic stellate cells to myofibroblasts
2000
Evaluation of hepatotropic targeting properties of allogenic and xenogenic erythrocyte ghosts in normal and liver‐injured rats
2007
TGF-β-mediated hepatocellular apoptosis by rat and human hepatoma cells and primary rat hepatocytes
1997
N-Acetyl-l-cysteine suppresses TGF-β signaling at distinct molecular steps: The biochemical and biological efficacy of a multifunctional, antifibrotic drug
2005
Differential effects of TGF-β on connective tissue growth factor (CTGF/CCN2) expression in hepatic stellate cells and hepatocytes
2007
Identification of Endoglin in Rat Hepatic Stellate Cells
2004
Connective tissue growth factor is a Smad2 regulated amplifier of transforming growth factor β actions in hepatocytes—But without modulating bone morphogenetic protein 7 signaling†
2009
Identification and Partial Characterization of A Hepatocyte–Derived Factor Promoting Proliferation of Cultured Fat–Storing Cells (Parasinusoidal Lipocytes)
1992
Molecular dissection of the mitogenic effect of hepatocytes on cultured hepatic stellate cells
1995
Treatment of rat hepatocytes with transforming growth factor ? increases their mitogenic activity for cultured fat storing cells
1995
The relation between hepatocellular damage and activation of fat-storing cell proliferation in vitro
1994
Connective Tissue Growth Factor in Serum as a New Candidate Test for Assessment of Hepatic Fibrosis
2006
Adenoviral delivery of an antisense RNA complementary to the 3' coding sequence of transforming growth factor-beta1 inhibits fibrogenic activities of hepatic stellate cells.
2002
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