Citation Impact
Citing Papers
Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
2011 Standout
Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)
2001 StandoutScience
Elucidation and refinement of synthetic receptor mechanisms
2020
Transcriptome analysis of HER2 reveals a molecular connection to fatty acid synthesis.
2003
Ribosomal S6 Kinase 2 Directly Phosphorylates the 5-Hydroxytryptamine 2A (5-HT2A) Serotonin Receptor, Thereby Modulating 5-HT2A Signaling
2008
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Receptor-specific Ubiquitination of β-Arrestin Directs Assembly and Targeting of Seven-transmembrane Receptor Signalosomes
2005 StandoutNobel
Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions
2024 StandoutNobel
ATF4 Is a Substrate of RSK2 and an Essential Regulator of Osteoblast Biology
2004
Mechanisms of type-I- and type-II-interferon-mediated signalling
2005 Standout
MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14
2003
mTOR Signaling in Growth Control and Disease
2012 Standout
Coordinating ERK/MAPK signalling through scaffolds and inhibitors
2005 Standout
Inflammation and metabolic disorders
2006 StandoutNature
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
2012 Standout
PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP
2005
Inflammatory links between obesity and metabolic disease
2011 Standout
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
2007 Standout
Altered ERK/MAPK signaling in the hippocampus of the mrsk2_KO mouse model of Coffin‐Lowry syndrome
2011
The Human Obesity Gene Map: The 2005 Update
2006
The metabolic syndrome
2010 Standout
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
2008 Standout
RSK2 Activity Is Regulated by Its Interaction with PEA-15
2003
Cancer Cell Metabolism: Warburg and Beyond
2008 Standout
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
2012 Standout
Function and Regulation of CREB Family Transcription Factors in the Nervous System
2002 Standout
The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions
2006
Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma
2016
Essential role of RSK2 in c-Fos–dependent osteosarcoma development
2005
Oncogenic properties of the endogenous fatty acid metabolism: molecular pathology of fatty acid synthase in cancer cells
2006
Cloning and Characterization of Xenopus Rsk2, the Predominant p90 Rsk Isozyme in Oocytes and Eggs
2000
Skeletal remodeling in health and disease
2007 Standout
The RSK factors of activating the Ras/MAPK signaling cascade
2008
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
The metabolic syndrome
2005 Standout
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
Cellular processing of platinum anticancer drugs
2005 Standout
MAP kinase‐mediated phosphoacetylation of histone H3 and inducible gene regulation
2003
mTOR: from growth signal integration to cancer, diabetes and ageing
2010 Standout
MSK1 is required for CREB phosphorylation in response to mitogens in mouse embryonic stem cells
2000
Obesity Associated with a Mutation in a Genetic Regulator of Adipocyte Differentiation
1998
Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling
2011 StandoutNobel
Adipocyte functions are modulated by cell size change: potential involvement of an integrin/ERK signalling pathway
2003
Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway
2000
Programmable synthetic receptors: the next-generation of cell and gene therapies
2024
The renin-angiotensin system and natriuretic peptides in obesity-associated hypertension
2000
PPARγ signaling and metabolism: the good, the bad and the future
2013 Standout
Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis
2006
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
Obesity and the Risk of Heart Failure
2002 Standout
Why does tumor-associated fatty acid synthase (oncogenic antigen-519) ignore dietary fatty acids?
2004
LTP and LTD
2004 Standout
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Pharmacological inhibition of fatty acid synthase (FAS): A novel therapeutic approach for breast cancer chemoprevention through its ability to suppress Her‐2/neu (erbB‐2) oncogene‐induced malignant transformation
2004
Transcriptional regulation of hepatic lipogenesis
2015
Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins
2004 Standout
Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B–containing lipoproteins
2008 StandoutNobel
AKT/PKB Signaling: Navigating the Network
2017 Standout
Epigenetic modifications and human disease
2010 Standout
Bile Acids Enhance Low Density Lipoprotein Receptor Gene Expression via a MAPK Cascade-mediated Stabilization of mRNA
2002
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
RPS6KA2, a putative tumour suppressor gene at 6q27 in sporadic epithelial ovarian cancer
2006
Transcriptional regulation by the phosphorylation-dependent factor CREB
2001 Standout
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
MAPK cascade signalling and synaptic plasticity
2004
Genetics of Food Intake Self-Regulation in Childhood: Literature Review and Research Opportunities
2013 Standout
Clinical and molecular overview of inherited disorders resulting from epigenomic dysregulation
2009
Molecular mechanisms of mTOR-mediated translational control
2009 Standout
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
2008 Standout
Insulin signalling mechanisms for triacylglycerol storage
2013
Integrating cell-signalling pathways with NF-κB and IKK function
2006 Standout
Neurodegeneration Is Associated to Changes in Serum Insulin-like Growth Factors
2000
Pathophysiology of Human Visceral Obesity: An Update
2013 Standout
Clues from cell metabolism
2010 StandoutNatureNobel
ERK and p38 MAPK-Activated Protein Kinases: a Family of Protein Kinases with Diverse Biological Functions
2004 Standout
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c
2002
Essential role of RSK2 in c-Fos–dependent osteosarcoma development
2005
De Novo Lipogenesis Products and Endogenous Lipokines
2016
Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity
2016 Standout
MSK1 and MSK2 Are Required for the Mitogen- and Stress-Induced Phosphorylation of CREB and ATF1 in Fibroblasts
2002
Regulation and function of the RSK family of protein kinases
2011
p90 ribosomal S6 kinase 2 is associated with and dephosphorylated by protein phosphatase 2Cδ
2004
Acute dietary fat intake initiates alterations in energy metabolism and insulin resistance
2017
Activation of protein kinase B/cAkt in hepatocytes is sufficient for the induction of expression of the gene encoding glucokinase
2000
Regulation of Microsomal Triglyceride Transfer Protein Gene by Insulin in HepG2 Cells
2003
Inhibition of Microsomal Triglyceride Transfer Protein Expression and Apolipoprotein B100 Secretion by the Citrus Flavonoid Naringenin and by Insulin Involves Activation of the Mitogen-Activated Protein Kinase Pathway in Hepatocytes
2005
The Role of Iron in Diabetes and Its Complications
2007
Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*
1999 Standout
Synergistic Activation of Human LDL Receptor Expression by SCAP Ligand and Cytokine Oncostatin M
2003
Works of Birgit Knebel being referenced
Sterol regulatory element binding proteins (SREBP)-1a and SREBP-2 are linked to the MAP-kinase cascade
2000
Metabolic syndrome and hypertension: pathophysiology and molecular basis of insulin resistance
1998
The peroxisome proliferator activated receptor gamma Pro12Ala polymorphism is associated with a lower hirsutism score and increased insulin sensitivity in women with polycystic ovary syndrome
2005
Synthetic cytokine receptors transmit biological signals using artificial ligands
2018
Preventing Phosphorylation of Sterol Regulatory Element-Binding Protein 1a by MAP-Kinases Protects Mice from Fatty Liver and Visceral Obesity
2012
Defects of Insulin and IGF-1 Action at Receptor and Postreceptor Level in a Patient with Type A Syndrome of Insulin Resistance
1997
Liver-Specific Expression of Transcriptionally Active SREBP-1c Is Associated with Fatty Liver and Increased Visceral Fat Mass
2012
Variants in Genes Controlling Oxidative Metabolism Contribute to Lower Hepatic ATP Independent of Liver Fat Content in Type 1 Diabetes
2016
Tissue-Specific Differences in the Development of Insulin Resistance in a Mouse Model for Type 1 Diabetes
2014
Ribosomal subunit kinase-2 is required for growth factor-stimulated transcription of the c- Fos gene
2000
Mechanisms of Insulin Resistance in Primary and Secondary Nonalcoholic Fatty Liver
2017
An association between NIDDM and a GAA trinucleotide repeat polymorphism in the X25/frataxin (Friedreich's ataxia) gene.
1998