Citation Impact
Citing Papers
Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of β-tubulin (Asp26Glu) and less stable microtubules
2006
Mutations in topoisomerase I as a self-resistance mechanism coevolved with the production of the anticancer alkaloid camptothecin in plants
2008
Pharmacologic Targeting of Hypoxia-Inducible Factors
2019 StandoutNobel
Molecular Mechanisms of Patupilone Resistance
2008
Epothilones – A fascinating family of microtubule stabilizing antitumor agents
2008
Fragrance chemistry
1998
Targeting microbial biofilms: current and prospective therapeutic strategies
2017 Standout
Cell mechanics and the cytoskeleton
2010 StandoutNature
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
The evolving role of natural products in drug discovery
2005 Standout
Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites
2007
Small Molecules, Big Impact
2002
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
2007 Standout
Mesoporous silica nanoparticles in biomedical applications
2012 StandoutNobel
Brominated Derivatives of Noscapine Are Potent Microtubule-interfering Agents That Perturb Mitosis and Inhibit Cell Proliferation
2003
Mechanisms and strategies to overcome chemotherapy resistance in metastatic breast cancer
2008
Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology
2013 Standout
Transforming Growth Factor-β Signaling in Immunity and Cancer
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Marine natural products
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Cancer drug resistance: an evolving paradigm
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Making Epothilones Fluoresce: Design, Synthesis, and Biological Characterization of a Fluorescent N12‐Aza‐Epothilone (Azathilone)
2009
Mechanisms of Taxol resistance related to microtubules
2003
Selection of boron reagents for Suzuki–Miyaura coupling
2013 Standout
Catalytic Antibody Route to the Naturally Occurring Epothilones: Total Synthesis of Epothilones A-F
2001
Microtubule structure and its stabilisation
2004
Altered TUBB3 expression contributes to the epothilone response of mitotic cells
2013
Anticancer therapy with novel tubulin-interacting drugs
2001
Pyrrolidinyl‐Spirooxindole Natural Products as Inspirations for the Development of Potential Therapeutic Agents
2007 Standout
Tumor-Associated Macrophages: From Mechanisms to Therapy
2014 Standout
Phase I trial of oral MAC-321 in subjects with advanced malignant solid tumors
2006
Development of Novel Chemotherapeutic Agents to Evade the Mechanisms of Multidrug Resistance (MDR)
2005
Epothilones in the treatment of cancer
2006
Porous Protein Crystals as Reaction Vessels for Controlling Magnetic Properties of Nanoparticles
2012 StandoutNobel
Profound Methyl Effects in Drug Discovery and a Call for New CH Methylation Reactions
2013
Primary‐Amine‐Catalyzed Enantioselective Intramolecular Aldolizations
2008 StandoutNobel
Paclitaxel plus Bevacizumab versus Paclitaxel Alone for Metastatic Breast Cancer
2007 Standout
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Synthesis and biological evaluation of novel oxophenylarcyriaflavins as potential anticancer agents
2008
High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis
2014 StandoutNobel
Microtubule-binding agents: a dynamic field of cancer therapeutics
2010 Standout
Enantioselectivity of the musk odor sensation
2001
A General Solution for the 2‐Pyridyl Problem
2012
tBuLi‐Mediated One‐Pot Direct Highly Selective Cross‐Coupling of Two Distinct Aryl Bromides
2015 StandoutNobel
Microtubules as a target for anticancer drugs
2004 Standout
Paul Ehrlich's magic bullet concept: 100 years of progress
2008 Standout
Highly Selective Metalations of Pyridines and Related Heterocycles Using New Frustrated Lewis Pairs or tmp‐Zinc and tmp‐Magnesium Bases with BF3⋅OEt2
2010
Accompanying protein alterations in malignant cells with a microtubule-polymerizing drug-resistance phenotype and a primary resistance mechanism 1 1Abbreviations: MTs, microtubules; MAPs, microtubule-associated proteins; MAP4, microtubule-associated protein-4; PTX, paclitaxel; EPOA, epothilone A; EPOB, epothilone B; EPOA-R, epothilone A-resistant; COL, colchicine; VCR, vincristine; and VBL, vinblastine.
2001
Neutrophils in cancer: neutral no more
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The anti-angiogenic basis of metronomic chemotherapy
2004 Standout
Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies
2006 Standout
Catalytic CC, CN, and CO Ullmann‐Type Coupling Reactions
2009 Standout
Asymmetric Multicomponent Reactions (AMCRs): The New Frontier
2005 Standout
Iron‐Catalyzed C(sp2)H and C(sp3)H Methylations of Amides and Anilides
2015
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
Pyridines via solid-supported [2 + 2 + 2] cyclotrimerization
2006
3d Transition Metals for C–H Activation
2018 Standout
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Chemistry of Polyvalent Iodine
2008 Standout
Proteinkristalle als neue Katalysatoren
2001
β-Tubulin Mutations Are Associated with Resistance to 2-Methoxyestradiol in MDA-MB-435 Cancer Cells
2005
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.
2003
Ixabepilone: targeting βIII-tubulin expression in taxane-resistant malignancies
2009
Neuronal-associated microtubule proteins class III beta-tubulin and MAP2c in neuroblastoma: role in resistance to microtubule-targeted drugs.
2004
Synthesis of Epothilone 16,17‐Alkyne Analogs by Replacement of the C13−C15(O)‐Ring Segment of Natural Epothilone C
2003
Eribulin mesylate: A novel halichondrin B analogue for the treatment of metastatic breast cancer
2012
Synthesis of Pyridine and Dihydropyridine Derivatives by Regio- and Stereoselective Addition toN-Activated Pyridines
2012 Standout
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition
2009 Standout
BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy.
2001
Multiple microtubule alterations are associated with Vinca alkaloid resistance in human leukemia cells.
2001
Peloruside A Does Not Bind to the Taxoid Site on β-Tubulin and Retains Its Activity in Multidrug-Resistant Cell Lines
2004
Allerlei Trends: die neuesten Entwicklungen in der Riechstoffchemie
2000
Enantioselective perception of chiral odorants
2003
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
2012 Standout
Both Microtubule-Stabilizing and Microtubule-Destabilizing Drugs Inhibit Hypoxia-Inducible Factor-1α Accumulation and Activity by Disrupting Microtubule Function
2005
Chemical Synthesis and Biological Evaluation of Second‐Generation Palmerolide A Analogues
2010
Functional Nanomaterials for Phototherapies of Cancer
2014 Standout
Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs.
2002
Catalytic Enantioselective Addition of Allylic Organometallic Reagents to Aldehydes and Ketones
2003 Standout
Selected Patented Cross-Coupling Reaction Technologies
2006 Standout
General Method for Synthesis of 2-Heterocyclic N-Methyliminodiacetic Acid Boronates
2010
Stereoselective Cyclopropanation Reactions
2003 Standout
Total Synthesis of (−)-Anisatin
2012
Odds and Trends: Recent Developments in the Chemistry of Odorants
2000
The Binding Mode of Epothilone A on α,ß-Tubulin by Electron Crystallography
2004 Science
Biochemical genetic analysis of indanocine resistance in human leukemia.
2001
(Z)-Sarcodictyin A, a New Highly Cytotoxic Diterpenoid from the Soft Coral Bellonella albiflora
2003
Metalated Heterocycles and Their Applications in Synthetic Organic Chemistry
2004
Alternative Synthetic Methods through New Developments in Catalysis by Gold
2008 Standout
Inactivation of chemokine (C-C motif) receptor 1 (CCR1) suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model
2010
Synthesis of Optically Active 6‐Alkynyl‐ and 6‐Alkylpurines as Cytokinin Analogs and Inhibitors of 15‐Lipoxygenase; Studies of Intramolecular Cyclization of 6‐(Hydroxyalkyn‐1‐yl)purines
2005
Functional Oligothiophenes: Molecular Design for Multidimensional Nanoarchitectures and Their Applications
2009 Standout
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
First efficient synthesis of novel oxophenyl-arcyriaflavin analogs
2005
Transition-Metal-Catalyzed Reactions in Heterocyclic Synthesis
2004 Standout
Emerging Targets in Photopharmacology
2016 StandoutNobel
Chemical Synthesis and Biological Evaluation of cis- and trans-12,13-Cyclopropyl and 12,13-Cyclobutyl Epothilones and Related Pyridine Side Chain Analogues
2001
Total Synthesis and Antitumor Activity of 12,13-Desoxyepothilone F: An Unexpected Solvolysis Problem at C15, Mediated by Remote Substitution at C21
2000
Chemical Synthesis and Biological Evaluation of Palmerolide A Analogues
2008
A General Solution for the 2‐Pyridyl Problem
2012
MAC-321, a novel taxane with greater efficacy than paclitaxel and docetaxel in vitro and in vivo.
2003
Applied Hydroformylation
2012 Standout
Metal-Free Multicomponent Syntheses of Pyridines
2014 Standout
Development of Novel Drugs from Marine Surface Associated Microorganisms
2010
Optimization of the Conditions for Copper‐Mediated N‐Arylation of Heteroarylamines
2007
Works of Birgit Bollbuck being referenced
A Potent and Selective S1P1 Antagonist with Efficacy in Experimental Autoimmune Encephalomyelitis
2012
Chemical synthesis and biological properties of pyridine epothilones
2000
Total Synthesis of 16-Desmethylepothilone B, Epothilone B10, Epothilone F, and Related Side Chain Modified Epothilone B Analogues
2000
Design and preparation of 2-benzamido-pyrimidines as inhibitors of IKK
2005
A common pharmacophore for epothilone and taxanes: Molecular basis for drug resistance conferred by tubulin mutations in human cancer cells
2000
Nature-like odorants by stereoselective ring enlargement of cyclohexanone and cyclododecanone
1996
Novel chiral building blocks derived from Baker's yeast reduction products: Synthesis and odour of mono- and bicyclic macrolides
1999
Stereoselective synthesis and structural variations of ethyl analogues of galbanum macrolides
1999
Bridged Piperazines and Piperidines as CCR1 Antagonists with Oral Activity in Models of Arthritis and Multiple Sclerosis
2006