Citation Impact
Citing Papers
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
2001 StandoutScienceNobel
Structure of apo-CAP reveals that large conformational changes are necessary for DNA binding
2009 StandoutNobel
HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing
2001 StandoutScienceNobel
Rapid protein fold determination using unassigned NMR data
2003 StandoutNobel
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
RcoM: A New Single-Component Transcriptional Regulator of CO Metabolism in Bacteria
2008
Visualization of the movement of single histidine kinase molecules in live Caulobacter cells
2004 StandoutNobel
Site-specific protein modifications through pyrroline-carboxy-lysine residues
2011
The Human SepSecS-tRNA Sec Complex Reveals the Mechanism of Selenocysteine Formation
2009 StandoutScienceNobel
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
2020 StandoutScience
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models
2016 StandoutNatureNobel
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
2000 StandoutNature
Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA
2007
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Iron Coordination Structures of Oxygen Sensor FixL Characterized by Fe K-edge Extended X-ray Absorption Fine Structure and Resonance Raman Spectroscopy
1999
Crystal structure of the human COP9 signalosome
2014 Nature
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
2001 StandoutNobel
Circadian Mutant Overtime Reveals F-box Protein FBXL3 Regulation of Cryptochrome and Period Gene Expression
2007
Taking it step by step: mechanistic insights from structural studies of ubiquitin/ubiquitin-like protein modification pathways
2007
Protein dynamics and conformational disorder in molecular recognition
2009
Structure of the GAF domain, a ubiquitous signaling motif and a new class of cyclic GMP receptor
2000
ACE2 X-Ray Structures Reveal a Large Hinge-bending Motion Important for Inhibitor Binding and Catalysis
2004
HIF-1, O2, and the 3 PHDs
2001 StandoutNobel
Natural expansion of the genetic code
2006
The pyrrolysine translational machinery as a genetic-code expansion tool
2011
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Nonredundant Roles of the mPer1 and mPer2 Genes in the Mammalian Circadian Clock
2001
Bacterial redox sensors
2004
Pyrrolysine analogues as substrates for pyrrolysyl‐tRNA synthetase
2006
Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of pyrrolysyl-tRNA synthetase from the methanogenic archaeonMethanosarcina mazei
2006
Two-component and phosphorelay signal transduction
2000
Comprehensive analysis of loops at protein-protein interfaces for macrocycle design
2014
Structural Basis of Outer Membrane Protein Biogenesis in Bacteria
2011
Regulation of a transcription factor network by Cdk1 coordinates late cell cycle gene expression
2014
Perspectives on Oxygen Sensing
1999 StandoutNobel
Direct charging of tRNACUA with pyrrolysine in vitro and in vivo
2004 Nature
The direct genetic encoding of pyrrolysine
2005
Design and Signaling Mechanism of Light-Regulated Histidine Kinases
2008
Coordination of circadian timing in mammals
2002 StandoutNature
Redox Control of Protein Conformation in Flavoproteins
2009
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Skp’n with Cks1: Revelations from the Skp1-Skp2-Cks1-p27 Structure
2005
Mammalian Oxygen Sensing, Signalling and Gene Regulation
2000
Preservation of light signaling to the suprachiasmatic nucleus in vitamin A-deficient mice
2001 StandoutNobel
RadicalS-Adenosylmethionine Enzymes
2014
Blue-Light Photoreceptors in Higher Plants
1999
The transition state for formation of the peptide bond in the ribosome
2006 StandoutNobel
The Many Faces of Vitamin B12: Catalysis by Cobalamin-Dependent Enzymes
2003
Structure of a flavin-binding plant photoreceptor domain: Insights into light-mediated signal transduction
2001
Photoswitchable Intramolecular H-Stacking of Perylenebisimide
2010 StandoutNobel
Ramshackle (Brwd3) promotes light-induced ubiquitylation of Drosophila Cryptochrome by DDB1-CUL4-ROC1 E3 ligase complex
2013 StandoutNobel
Addition of the keto functional group to the genetic code of Escherichia coli
2002
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
2002 StandoutNobel
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
ATG Systems from the Protein Structural Point of View
2009 StandoutNobel
An aminoacyl-tRNA synthetase that specifically activates pyrrolysine
2004
Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation
2007 StandoutNobel
The molecular logic of Notch signaling – a structural and biochemical perspective
2008
Reaction mechanism of Drosophila cryptochrome
2010 StandoutNobel
Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice
2000 StandoutNobel
PAS Domains: Internal Sensors of Oxygen, Redox Potential, and Light
1999
Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase
2013 StandoutNobel
Building and remodelling Cullin–RING E3 ubiquitin ligases
2013
Two-Component Signal Transduction
2000 Standout
RING Domain E3 Ubiquitin Ligases
2009 Standout
A Pictet-Spengler ligation for protein chemical modification
2012 StandoutNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Architecture and function of metallopeptidase catalytic domains
2013
Phototropin Blue-Light Receptors
2006
Further evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination
2009 StandoutNobel
Artificial ligand binding within the HIF2α PAS-B domain of the HIF2 transcription factor
2009
The cancer connection
2002 StandoutNatureNobel
A Bioorthogonal Quadricyclane Ligation
2011 StandoutNobel
Chemically tunable mucin chimeras assembled on living cells
2015 StandoutNobel
Ultrafast Dynamics of Flavins in Five Redox States
2008 StandoutNobel
Heme Protein Assemblies
2004
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples
2012 StandoutNobel
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
Ultrafast Dynamics and Anionic Active States of the Flavin Cofactor in Cryptochrome and Photolyase
2008 StandoutNobel
LOV (light, oxygen, or voltage) domains of the blue-light photoreceptor phototropin (nph1): Binding sites for the chromophore flavin mononucleotide
1999
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
A Leucine-Rich Repeat Protein Provides a SHOC2 the RAS Circuit: a Structure-Function Perspective
2021
Structure and Function of DNA Photolyase and Cryptochrome Blue-Light Photoreceptors
2003 StandoutNobel
Works of Bing Hao being referenced
A New UAG-Encoded Residue in the Structure of a Methanogen Methyltransferase
2002 Science
Crystal Structure of a Novel Carboxypeptidase from the Hyperthermophilic Archaeon Pyrococcus furiosus
2002
Specific Small Molecule Inhibitors of Skp2-Mediated p27 Degradation
2012
SCCRO (DCUN1D1) Is an Essential Component of the E3 Complex for Neddylation
2008
Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases
2007
Structural Basis of the Cks1-Dependent Recognition of p27Kip1 by the SCFSkp2 Ubiquitin Ligase
2005
Reactivity and Chemical Synthesis of L-Pyrrolysine— the 22nd Genetically Encoded Amino Acid
2004
Crystal Structure of the Escherichia coli Peptide Deformylase,
1997
New Mechanistic Insights from Structural Studies of the Oxygen-Sensing Domain of Bradyrhizobium japonicum FixL,
2000
Structure of a biological oxygen sensor: A new mechanism for heme-driven signal transduction
1998