Citation Impact
Citing Papers
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels
2006 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
The development of proteasome inhibitors as anticancer drugs
2004
The Concept of Synthetic Lethality in the Context of Anticancer Therapy
2005 StandoutNobel
Apoptosis in the nervous system
2000 StandoutNature
Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
2009 Standout
Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis
1998 Standout
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
2003 StandoutNobel
Proteasome inhibitors: from research tools to drug candidates
2001
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
2000 StandoutNature
Pyrrolidine dithiocarbamate-zinc(II) and -copper(II) complexes induce apoptosis in tumor cells by inhibiting the proteasomal activity
2008
Dietary flavonoids as proteasome inhibitors and apoptosis inducers in human leukemia cells
2005
Shared Principles in NF-κB Signaling
2008 Standout
Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells
2005
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
The Inflammasome
2002 Standout
Molecular Targets for Green Tea in Prostate Cancer Prevention
2003
Copper in diseases and treatments, and copper‐based anticancer strategies
2009
Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis
2000 StandoutNobel
An APAF-1·Cytochrome c Multimeric Complex Is a Functional Apoptosome That Activates Procaspase-9
1999 Standout
The Hallmarks of Cancer
2000 Standout
Extracellular Proteins Organize the Mechanosensory Channel Complex in C. elegans Touch Receptor Neurons
2004 StandoutNobel
Cell Death
2004 Standout
Regulation of apoptosis by the ubiquitin and proteasome pathway
2002
Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
2012 Standout
The biochemistry of apoptosis
2000 StandoutNature
Cancer genes and the pathways they control
2004 Standout
Mechanically Activated Ion Channels
2015 StandoutNobel
The mechanosensory protein MEC-6 is a subunit of the C. elegans touch-cell degenerin channel
2002 StandoutNatureNobel
Protein degradation and protection against misfolded or damaged proteins
2003 StandoutNature
The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals
2004 StandoutNobel
Proteasome inhibition in cancer: Development of PS-341
2001
Ester Bond-containing Tea Polyphenols Potently Inhibit Proteasome Activity in Vitro and in Vivo
2001
Tea Beverage in Chemoprevention of Prostate Cancer: A Mini-Review
2003
Chronic Myelogenous Leukemia
2002
Apoptosis
2002 Standout
Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade
1997 Standout
Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition
2000 Standout
Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors
1998 Standout
The Proteasome
2001
Turning Tumor-Promoting Copper into an Anti-Cancer Weapon via High-Throughput Chemistry
2010
Molecular characterization of mitochondrial apoptosis-inducing factor
1999 StandoutNature
IκB kinase complexes: gateways to NF-κB activation and transcription
2006
The proteasome: a suitable antineoplastic target
2004
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Autoimmunity and Apoptosis
2001 StandoutNobel
Disulfiram promotes the conversion of carcinogenic cadmium to a proteasome inhibitor with pro-apoptotic activity in human cancer cells
2008
Chapter 11 Proteinase families and their inhibitors
2001
Neurosensory mechanotransduction
2008 StandoutNobel
Proteasome inhibitors: fromin vitro uses to clinical trials
2000
Caspase Activation Inhibits Proteasome Function during Apoptosis
2004 StandoutNobel
Organic copper complexes as a new class of proteasome inhibitors and apoptosis inducers in human cancer cells
2003
Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death
2001 StandoutScience
Inhibition of the Proteasome Activity by Gallium(III) Complexes Contributes to Their Anti–Prostate Tumor Effects
2007
Development of the Proteasome Inhibitor PS-341
2002
The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na + channels
2004 StandoutNobel
Synthetic Analogs of Green Tea Polyphenols as Proteasome Inhibitors
2002
Celastrol, a Triterpene Extracted from the Chinese “Thunder of God Vine,” Is a Potent Proteasome Inhibitor and Suppresses Human Prostate Cancer Growth in Nude Mice
2006 Standout
CEP1612, a dipeptidyl proteasome inhibitor, induces p21WAF1 and p27KIP1 expression and apoptosis and inhibits the growth of the human lung adenocarcinoma A-549 in nude mice.
2001
PTEN Activity Is Modulated During Ischemia and Reperfusion
2005 StandoutNobel
Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway
2000 StandoutScience
Evaluation of copper-dependent proteasome-inhibitory and apoptosis-inducing activities of novel pyrrolidine dithiocarbamate analogues
2007
Pomegranate fruit juice for chemoprevention and chemotherapy of prostate cancer
2005 Standout
Molecular study on copper-mediated tumor proteasome inhibition and cell death
2010
Tannic acid potently inhibits tumor cell proteasome activity, increases p27 and Bax expression, and induces G1 arrest and apoptosis.
2001
Death Receptors: Signaling and Modulation
1998 StandoutScience
Sodium diethyldithiocarbamate, an AIDS progression inhibitor and a copper-binding compound, has proteasome-inhibitory and apoptosis-inducing activities in cancer cells
2007
Induction of tumor cell apoptosis by taurine Schiff base copper complex is associated with the inhibition of proteasomal activity
1998
Phosphatase inhibitors increase the open probability of ENaC in A6 cells
2002
Clioquinol, a Therapeutic Agent for Alzheimer's Disease, Has Proteasome-Inhibitory, Androgen Receptor–Suppressing, Apoptosis-Inducing, and Antitumor Activities in Human Prostate Cancer Cells and Xenografts
2007
Proteasome Inhibition As a Novel Therapeutic Target in Human Cancer
2005
L-glutamine Schiff base copper complex as a proteasome inhibitor and an apoptosis inducer in human cancer cells
1992
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis
2000 StandoutScience
Proteasome inhibitors as potential novel anticancer agents
1999
Bax degradation by the ubiquitin/proteasome-dependent pathway: Involvement in tumor survival and progression
2000
Mitochondria and Apoptosis
1998 StandoutScience
Decoding the Patterns of Self and Nonself by the Innate Immune System
2002 StandoutScience
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
The Cyclin-dependent Kinase Cdk2 Regulates Thymocyte Apoptosis
1999
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Emerging Targets in Photopharmacology
2016 StandoutNobel
Multiple Myeloma
2011 Standout
Disulfiram, a Clinically Used Anti-Alcoholism Drug and Copper-Binding Agent, Induces Apoptotic Cell Death in Breast Cancer Cultures and Xenografts via Inhibition of the Proteasome Activity
2006
Caspases: Enemies Within
1998 StandoutScience
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Novel 8-hydroxylquinoline analogs induce copper-dependent proteasome inhibition and cell death in human breast cancer cells
2009
Regulation of Cell Death Protease Caspase-9 by Phosphorylation
1998 StandoutScience
A Matter of Life and Cell Death
1998 Science
Works of Bing An being referenced
Endogenously Expressed Epithelial Sodium Channel Is Present in Lipid Rafts in A6 Cells
2002
Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts
1998
Failure to activate interleukin 1β‐converting enzyme‐like proteases and to cleave retinoblastoma protein in drug‐resistant cells
1996
IκB Kinase-β (IKKβ) Modulation of Epithelial Sodium Channel Activity
2004
Fas stimulation induces RB dephosphorylation and proteolysis that is blocked by inhibitors of the ICE protease family
1997
Characterization of interior cleavage of retinoblastoma protein in apoptosis
1997
Proteasome Inhibition Leads to Significant Reduction of Bcr-Abl Expression and Subsequent Induction of Apoptosis in K562 Human Chronic Myelogenous Leukemia Cells
1999
Cell surface expression and turnover of the α-subunit of the epithelial sodium channel
2001