Citation Impact
Citing Papers
Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve
2011 Standout
Pathophysiology of Migraine: A Disorder of Sensory Processing
2017 Standout
Catalytic Functionalization of C(sp2)H and C(sp3)H Bonds by Using Bidentate Directing Groups
2013 Standout
A multi-substrate screening approach for the identification of a broadly applicable Diels–Alder catalyst
2019 StandoutNobel
Hypothalamic regulation of sleep and circadian rhythms
2005 StandoutNature
Imidazolones in Diastereoselective Cyclization Reactions and CuII‐Catalysed Cross‐Coupling Reactions
2009 StandoutNobel
CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals
2012 Standout
8-Fluoroimidazo[1,2-a]pyridine: Synthesis, physicochemical properties and evaluation as a bioisosteric replacement for imidazo[1,2-a]pyrimidine in an allosteric modulator ligand of the GABAA receptor
2006
Introduction of Fluorine and Fluorine‐Containing Functional Groups
2013 Standout
New Structural Scaffolds for Centrally Acting Oxime Reactivators of Phosphylated Cholinesterases
2011 StandoutNobel
Selectfluor: Mechanistic Insight and Applications
2004
Recent advances in the transition metal-catalyzed twofold oxidative C–H bond activation strategy for C–C and C–N bond formation
2011 Standout
Synthesis of Extended π‐Systems through C–H Activation
2014 Standout
NADPH oxidase 4 deficiency leads to impaired wound repair and reduced dityrosine-crosslinking, but does not affect myofibroblast formation
2016
Cyclisation/fluorination of nitrogen containing dienes in superacid HF–SbF5: a new route to 3- and 4-fluoropiperidines
2008
Synthesis and structure–activity relationships of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide derivatives as potential agents against A549 lung cancer cells
2007
Reversal of pathological pain through specific spinal GABAA receptor subtypes
2008 Nature
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Critical new insights into the binding of poly- and perfluoroalkyl substances (PFAS) to albumin protein
2021
Amino acid derived 1,4‐dialkyl substituted imidazolones
2010 StandoutNobel
Industrial Applications of the Diels–Alder Reaction
2013
Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 1. Prediction of intestinal absorption
1999
Dural vasodilation causes a sensitization of rat caudal trigeminal neurones in vivo that is blocked by a 5‐HT1B/1D agonist
1999
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model
2002 Standout
Chloride channels as drug targets
2008
Evolving concepts in liver tissue modeling and implications forin vitrotoxicology
2008
The role of drug metabolizing enzymes in clearance
2014
The Cross‐Dehydrogenative Coupling of CH Bonds: A Versatile Strategy for CC Bond Formations
2013 Standout
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
T-type calcium channels regulate cortical plasticity in-vivo NR-D-08-7049
2009
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens
2015 StandoutNobel
Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry
2014 StandoutNobel
Controlled Microwave Heating in Modern Organic Synthesis
2004 Standout
Imidazo[1,2-a]pyrazin-8-ones, imidazo[1,2-d][1,2,4]triazin-8-ones and imidazo[2,1-f][1,2,4]triazin-8-ones as α2/α3 subtype selective GABAA agonists for the treatment of anxiety
2005
Cellular senescence: from physiology to pathology
2014 Standout
Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
2016 StandoutNobel
Establishment of Broadly Applicable Reaction Conditions for the Palladium-Catalyzed Direct Arylation of Heteroatom-Containing Aromatic Compounds
2009
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
Intramolecular Dipolar Cycloaddition Reactions of Azomethine Ylides
2005
3d Transition Metals for C–H Activation
2018 Standout
N,N‐Dimethylacetamide (DMA) as a Methylene Synthon for Regioselective Linkage of Imidazo[1,2‐a]pyridine
2016
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Chemistry of Polyvalent Iodine
2008 Standout
Continuous-Flow Synthesis of Deuterium-Labeled Antidiabetic Chalcones: Studies towards the Selective Deuteration of the Alkynone Core
2016
Natural Product Synthesis Using Multicomponent Reaction Strategies
2009 Standout
Recent advances in the synthesis of (hetero)aryl-substituted heteroarenes via transition metal-catalysed direct (hetero)arylation of heteroarene C–H bonds with aryl halides or pseudohalides, diaryliodonium salts, and potassium aryltrifluoroborates
2009
Direct C2-Alkylation of Azoles with Alcohols and Ethers through Dehydrogenative Cross-Coupling under Metal-Free Conditions
2011
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Scalable and Highly Diastereo- and Enantioselective Catalytic Diels–Alder Reaction of α,β-Unsaturated Methyl Esters
2018 StandoutNobel
Reversal of Persistent Fibrosis in Aging by Targeting Nox4-Nrf2 Redox Imbalance
2014
Molecular Properties That Influence the Oral Bioavailability of Drug Candidates
2002 Standout
A Survey of the Role of Noncovalent Sulfur Interactions in Drug Design
2015
Recent developments in solvent-free multicomponent reactions: a perfect synergy for eco-compatible organic synthesis
2012
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Synthesis of four enantiomerically pure 4-(4-carbamoyl-1,2,3-triazol-1-yl)-2,3-dihydroxy-1-methoxybutylphosphonic acids
2005
Applications of Deuterium in Medicinal Chemistry
2019
A new synthesis of functionalized imidazol-2-ones
2000
Practical Methodologies for the Synthesis of Indoles
2006 Standout
Catalytic Asymmetric [4+2]-Cycloaddition of Dienes with Aldehydes
2017 StandoutNobel
Selectfluor: Mechanismen und Anwendungen
2004
Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope
2011 Standout
The Origin of Chalcogen-Bonding Interactions
2017 Standout
Current methods for the synthesis of 2-substituted azoles
2004
Precise Modulation of CO2 Sorption in Ti8Ce2–Oxo Clusters: Elucidating Lewis Acidity of the Ce Metal Sites and Structural Flexibility
2024 StandoutNobel
Role of GABAA receptors in cognition
2009
The Catalytic Asymmetric Intermolecular Prins Reaction
2021 StandoutNobel
Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation
2007 Standout
Evaluation of Electron‐Deficient Phosphine Ligands for Direct Arylation of Heterocycles
2010
About Sleep's Role in Memory
2013 Standout
Current and Novel Approaches to the Drug Treatment of Schizophrenia
2001
Synthesis of RHPS4 via an anionic ring closing cascade
2008
A Novel Synthesis of Enantiopure Octahydropyrrolo[3,4-b]pyrroles by Intramolecular [3 + 2] Dipolar Cycloaddition on Chiral Perhydro-1,3-benzoxazines
2002
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
Construction of Enantiopure Pyrrolidine Ring System via Asymmetric [3+2]-Cycloaddition of Azomethine Ylides
2006 Standout
Rapid microwave-assisted solution phase synthesis of substituted 2-pyridone libraries
2004
Organocatalytic Synthesis of Spiro[pyrrolidin-3,3′-oxindoles] with High Enantiopurity and Structural Diversity
2009 Standout
Palladium-Catalyzed Carbonylative Cross-Coupling with Imines: A Multicomponent Synthesis of Imidazolones
2007
Per- and polyfluoroalkyl substances in the environment
2022 StandoutScience
Intramolecular Pd(II)-Catalyzed Cyclization of Propargylamides: Straightforward Synthesis of 5-Oxazolecarbaldehydes
2008
From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles
2011 Standout
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
A new strategy for 2-substituted indolylalkylamines: synthesis of 2-aryldihomotryptamines
2002
Novel Derivatives of 2-Pyridinemethylamine as Selective, Potent, and Orally Active Agonists at 5-HT1A Receptors
1999
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation
2009 Standout
Sulfamic Acid and Its N- and O-Substituted Derivatives
2013
Heterocyclic Nanographenes and Other Polycyclic Heteroaromatic Compounds: Synthetic Routes, Properties, and Applications
2016 Standout
A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO2+” Donor of Unprecedented Reactivity, Selectivity, and Scope
2017 StandoutNobel
Metal-Free Multicomponent Syntheses of Pyridines
2014 Standout
Analysis of GABAA Receptor Function and Dissection of the Pharmacology of Benzodiazepines and General Anesthetics Through Mouse Genetics
2004
Carbene Complexes of Nonmetals
2004
Works of Bindi Sohal being referenced
Selective, Orally Active γ-Aminobutyric Acid A α5 Receptor Inverse Agonists as Cognition Enhancers
2004
Rodent pharmacokinetics and receptor occupancy of the GABAA receptor subtype selective benzodiazepine site ligand L‐838417
2004
Prediction of Drug Clearance by Glucuronidation from in Vitro Data: Use of Combined Cytochrome P450 and UDP-Glucuronosyltransferase Cofactors in Alamethicin-Activated Human Liver Microsomes
2008
Utility of Long-Term Cultured Human Hepatocytes as an in Vitro Model for Cytochrome P450 Induction
2006
N′,2-Diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists
2006
TPA023 [7-(1,1-Dimethylethyl)-6-(2-ethyl-2 H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine], an Agonist Selective for α2- and α3-Containing GABAA Receptors, Is a Nonsedating Anxiolytic in Rodents and Primates
2005
Cyclic sulfamide γ-secretase inhibitors
2005
2,7-Diazabicyclo[3.3.0]octanes as novel h5-HT1D receptor agonists
1999
Validation of a Rapid Equilibrium Dialysis Approach for the Measurement of Plasma Protein Binding
2008
Application of a Deuterium Replacement Strategy to Modulate the Pharmacokinetics of 7-(3,5-dimethyl-1H-1,2,4-triazol-1-yl)-3-(4-methoxy-2-methylphenyl)-2,6-dimethylpyrazolo[5,1-b]oxazole, a Novel CRF1 Antagonist
2014
An Inhibitor of NADPH Oxidase-4 Attenuates Established Pulmonary Fibrosis in a Rodent Disease Model
2013
Enhancement of Oral Absorption in Selective 5-HT1DReceptor Agonists: Fluorinated 3-[3-(Piperidin-1-yl)propyl]indoles
1998
Synthesis and Biological Evaluation of 3-Heterocyclyl-7,8,9,10-tetrahydro-(7,10-ethano)-1,2,4-triazolo[3,4-a]phthalazines and Analogues as Subtype-Selective Inverse Agonists for the GABAAα5 Benzodiazepine Binding Site
2004
3-[3-(Piperidin-1-yl)propyl]indoles as Highly Selective h5-HT1D Receptor Agonists
1999
A Pyridazine Series of α2/α3 Subtype Selective GABAA Agonists for the Treatment of Anxiety
2006
Imidazo[1,2-a]pyrimidines as Functionally Selective and Orally Bioavailable GABAAα2/α3 Binding Site Agonists for the Treatment of Anxiety Disorders
2005
1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1,3-dihydroimidazol-2-one: A Selective High-Affinity Antagonist for the Human Dopamine D4Receptor with Excellent Selectivity over Ion Channels
1999
1,3-Diphenyl-4-imidazoline-2-thione
1996
The chemical evolution of N,N-dimethyl-2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethylamine (L-741,604) and analogues: Potent and selective agonists for 5-HT1D receptors
1996
Imidazo[1,2-b][1,2,4]triazines as α2/α3 subtype selective GABAA agonists for the treatment of anxiety
2006
3-Heteroaryl-2-pyridones: Benzodiazepine Site Ligands with Functional Selectivity for α2/α3-Subtypes of Human GABAA Receptor-Ion Channels
2002