Citation Impact
Citing Papers
A Novel Germline Variant in CSF3R Reduces N-Glycosylation and Exerts Potent Oncogenic Effects in Leukemia
2018 StandoutNobel
The Colony-Stimulating Factor 3 Receptor T640N Mutation Is Oncogenic, Sensitive to JAK Inhibition, and Mimics T618I
2015
Evolution of the Cancer Stem Cell Model
2014 Standout
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
2014 Standout
Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities
2022 Standout
UALCAN: An update to the integrated cancer data analysis platform
2022 Standout
Nix restores mitophagy and mitochondrial function to protect against PINK1/Parkin-related Parkinson’s disease
2017
2018
Directing polymorph specific calcium carbonate formation with de novo protein templates
2023 StandoutNobel
Inactivation of presenilins causes pre‐synaptic impairment prior to post‐synaptic dysfunction
2010 StandoutNobel
Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer
2014 Nature
Parkinson disease
2017 Standout
Update on otitis media – prevention and treatment
2014
Increased Basal Activity Is a Key Determinant in the Severity of Human Skeletal Dysplasia Caused by TRPV4 Mutations
2011
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
2010 Standout
Association of a Leukemic Stem Cell Gene Expression Signature With Clinical Outcomes in Acute Myeloid Leukemia
2010
The genetics of Parkinson disease: implications for neurological care
2006
Mechanism and medical implications of mammalian autophagy
2018 Standout
An overview on CALR and CSF3R mutations and a proposal for revision of WHO diagnostic criteria for myeloproliferative neoplasms
2014
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells
2011
The role of autophagy in neurodegenerative disease
2013 Standout
Neutrophilic leukocytosis in advanced stage polycythemia vera: hematopathologic features and prognostic implications
2015
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide
2007 Standout
Molecular pathogenesis of Parkinson disease: insights from genetic studies
2009
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
2015 Standout
Transient receptor potential channelopathies
2010
Enhanced MAPK signaling is essential for CSF3R-induced leukemia
2016
The emerging role of lncRNAs in cancer
2015 Standout
Ageing as a risk factor for neurodegenerative disease
2019 Standout
Structural basis of cytokine-mediated activation of ALK family receptors
2021 Nature
Improving de novo protein binder design with deep learning
2023 StandoutNobel
Long Noncoding RNAs in Cancer Pathways
2016 Standout
The changing landscape of atherosclerosis
2021 StandoutNature
Deciphering the role of heterozygous mutations in genes associated with parkinsonism
2007
Ligand Independence of the T618I Mutation in the Colony-stimulating Factor 3 Receptor (CSF3R) Protein Results from Loss of O-Linked Glycosylation and Increased Receptor Dimerization
2014
Parkinson's disease
2009 Standout
Mitochondria: In Sickness and in Health
2012 Standout
Delivery technologies for cancer immunotherapy
2019 Standout
Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin–protein ligase with monoubiquitylation capacity
2006
Epidemiology of Parkinson’s disease
2017 Standout
CSF3R T618I is a highly prevalent and specific mutation in chronic neutrophilic leukemia
2013
Clinical practice guideline on diagnosis and treatment of hyponatraemia
2014 Standout
Parkinson's disease
2015 Standout
Epidemiological, clinical, and genetic characteristics of early-onset parkinsonism
2006
Targeting the IL-6/JAK/STAT3 signalling axis in cancer
2018 Standout
An International MDS/MPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplastic/myeloproliferative neoplasms
2015
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Mechanisms of mitophagy
2010 Standout
TRPV4-pathy, a novel channelopathy affecting diverse systems
2010
The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans
2021 StandoutNobel
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
Lewy body Parkinson's disease in a large pedigree with 77Parkin mutation carriers
2005
Impaired dopamine release and synaptic plasticity in the striatum of Parkin−/− mice
2009
Genetics of Parkinson's disease
2016
DNA methylation-based biomarkers and the epigenetic clock theory of ageing
2018 Standout
Intrinsically disordered proteins and biomineralization
2016
10 Years of GWAS Discovery: Biology, Function, and Translation
2017 Standout
Artificial Intelligence in Cardiology
2018 Standout
Genetics of Parkinsonʼs disease
2005
Autoregulation of Parkin activity through its ubiquitin‐like domain
2011
The prognostic landscape of genes and infiltrating immune cells across human cancers
2015 Standout
Susceptibility to Childhood Pneumonia: A Genome-Wide Analysis
2016
Long Noncoding RNA and Cancer: A New Paradigm
2017 Standout
ASXL1 mutations are frequent and prognostically detrimental in CSF3R‐mutated chronic neutrophilic leukemia
2015
G-CSF and GM-CSF in Neutropenia
2015
JAK2 inhibitors for myeloproliferative neoplasms: what is next?
2017
What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease
2011
Maintenance of age in human neurons generated by microRNA-based neuronal conversion of fibroblasts
2016
Gene-set analysis based on the pharmacological profiles of drugs to identify repurposing opportunities in schizophrenia
2016
A long noncoding RNA connects c-Myc to tumor metabolism
2014
Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors
2016
Oxidative stress, mitochondrial damage and neurodegenerative diseases.
2013 Standout
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
Diagnosing and Managing Advanced Chronic Myeloid Leukemia
2015
Genomics of chronic neutrophilic leukemia
2016
Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
2015 Standout
A Mechanogenetic Model of Exercise-Induced Pulmonary Haemorrhage in the Thoroughbred Horse
2019
The relative utilities of genome-wide, gene panel, and individual gene sequencing in clinical practice
2017
The Role of Free Radicals in the Aging Brain and Parkinson’s Disease: Convergence and Parallelism
2012
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
2010 Standout
The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
2016 Standout
EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis
2018 Standout
Clinical Practice Guideline: Otitis Media with Effusion (Update)
2016 Standout
Works of Beth Wilmot being referenced
Therapeutically Targetable ALK Mutations in Leukemia
2015
A loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia
2009
Functional and genomic context in pathway analysis of GWAS data
2014
Distribution, type, and origin of Parkin mutations: Review and case studies
2004
OncogenicCSF3RMutations in Chronic Neutrophilic Leukemia and Atypical CML
2013
Androgen Receptor Promotes Ligand-Independent Prostate Cancer Progression through c-Myc Upregulation
2013
Translational gene mapping of cognitive decline
2006
PHENOTYPIC VARIABILITY IN INDIVIDUALS WITH TYPE V OSTEOGENESIS IMPERFECTA WITH IDENTICAL IFITM5 MUTATIONS.
2013
A gene expression signature of CD34+ cells to predict major cytogenetic response in chronic-phase chronic myeloid leukemia patients treated with imatinib
2009
Genetic susceptibility to chronic otitis media with effusion: Candidate gene single nucleotide polymorphisms
2013
Gene set analysis: A step‐by‐step guide
2015