Standout Papers
- Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner (2012)
- The Classical Complement Cascade Mediates CNS Synapse Elimination (2007)
- Complement and microglia mediate early synapse loss in Alzheimer mouse models (2016)
- Schizophrenia risk from complex variation of complement component 4 (2016)
Citation Impact
Citing Papers
Temporal calcium profiling of specific circadian neurons in freely moving flies
2017 StandoutNobel
Somatic action potentials are sufficient for late-phase LTP-related cell signaling
2002
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
2011 StandoutScience
New tools for studying microglia in the mouse and human CNS
2016
Treatment with a C5aR Antagonist Decreases Pathology and Enhances Behavioral Performance in Murine Models of Alzheimer’s Disease
2009
Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner
2017
Docosahexaenoic acid (DHA): a modulator of microglia activity and dendritic spine morphology
2015
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease
2014
An Expanded View of Complex Traits: From Polygenic to Omnigenic
2017 Standout
Siglec functions of microglia
2014
Benefits and limitations of genome-wide association studies
2019
Transcriptomic profiling of microglia and astrocytes throughout aging
2020
Distinct expression of C1q‐like family mRNAs in mouse brain and biochemical characterization of their encoded proteins
2010
Developmental Neuronal Death in Hippocampus Requires the Microglial CD11b Integrin and DAP12 Immunoreceptor
2008
An Unbiased Expression Screen for Synaptogenic Proteins Identifies the LRRTM Protein Family as Synaptic Organizers
2009
Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis
2015
Molecular dissection of reactive astrogliosis and glial scar formation
2009 Standout
Microglial clearance function in health and disease
2008
Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration
2018
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior
2014
High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis
2013 StandoutNobel
Purinergic modulation of synaptic signalling at the neuromuscular junction
2006
Microglial immune checkpoint mechanisms
2018
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
The myeloid cells of the central nervous system parenchyma
2010 Nature
Microglial brain region−dependent diversity and selective regional sensitivities to aging
2016
Astrocytes and Microglia as Major Players of Myelin Production in Normal and Pathological Conditions
2020
Glial Cell Development and Function in Zebrafish
2014
Presynaptic Neurexin-3 Alternative Splicing trans-Synaptically Controls Postsynaptic AMPA Receptor Trafficking
2013 StandoutNobel
Microglia in the developing brain: from immunity to behaviour
2010
The neuropoietic cytokine family in development, plasticity, disease and injury
2007
Reciprocal Regulation between Resting Microglial Dynamics and Neuronal Activity In Vivo
2012
Origin of Microglia: Current Concepts and Past Controversies
2015
Secretion of ATP from Schwann cells in response to uridine triphosphate
2005
Late onset Alzheimer’s disease genetics implicates microglial pathways in disease risk
2017
Adenosine receptors as therapeutic targets
2006 Standout
Function and Regulation of CREB Family Transcription Factors in the Nervous System
2002 Standout
Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing
2018
A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model
2013
Astrocyte barriers to neurotoxic inflammation
2015
Piezo proteins are pore-forming subunits of mechanically activated channels
2012 StandoutNatureNobel
Microglia and Wnt Pathways: Prospects for Inflammation in Alzheimer’s Disease
2020
Depletion of microglia and inhibition of exosome synthesis halt tau propagation
2015
Phagocytosis of apoptotic cells in homeostasis
2015
Interplay between innate immunity and Alzheimer disease: APOE and TREM2 in the spotlight
2018
Connexin-dependent transcellular transcriptomic networks in mouse brain
2007
The Role of Glial Adenosine Receptors in Neural Resilience and the Neurobiology of Mood Disorders
2005
Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells
2017
Nuclear calcium signaling controls CREB-mediated gene expression triggered by synaptic activity
2001
Progranulin in the hematopoietic compartment protects mice from atherosclerosis
2018
Perinatal white matter injury: The changing spectrum of pathology and emerging insights into pathogenetic mechanisms
2006
Apyrase and 5′-nucleotidase Activities in Synaptosomes from the Cerebral Cortex of Rats Experimentally Demyelinated with Ethidium Bromide and Treated with Interferon-β
2006
Oligodendrocytes express P2Y12 metabotropic receptor in adult rat brain
2006
Complement: a key system for immune surveillance and homeostasis
2010 Standout
Immune attack: the role of inflammation in Alzheimer disease
2015 Standout
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Pathophysiology and Therapeutic Potential of Purinergic Signaling
2006
Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer’s disease
2018
Association of the ecto‐ATPase NTPDase2 with glial cells of the peripheral nervous system
2003
Glia: listening and talking to the synapse
2001
The role of ERK signaling and the P2X receptor on mechanical pain evoked by movement of inflamed knee joint
2006
Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways
2002
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice
2013
Cellular Distribution and Functions of P2 Receptor Subtypes in Different Systems
2004
ATP affects both axons and Schwann cells of unmyelinated C fibres
2001
Imaging second messenger dynamics in developing neural circuits
2008
Atlas of Subcellular RNA Localization Revealed by APEX-Seq
2019
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
2020 StandoutNobel
Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons
2012 Standout
Host microbiota constantly control maturation and function of microglia in the CNS
2015 Standout
Nucleotide signaling in nervous system development
2006
Astrocytes: a central element in neurological diseases
2015
Complement regulators and inhibitory proteins
2009
Genomic Analysis of Reactive Astrogliosis
2012 Standout
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Microglia: unique and common features with other tissue macrophages
2014
Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression
1998 StandoutNatureNobel
Molecular physiology of p2x receptors and atp signalling at synapses
2001
New insights into the role of TREM2 in Alzheimer’s disease
2018
Purinergic signalling in neuron–glia interactions
2006
Extracellular Matrix: Functions in the Nervous System
2010
Debris clearance by microglia: an essential link between degeneration and regeneration
2008
Calcium oscillations increase the efficiency and specificity of gene expression
1998 StandoutNature
The birth and postnatal development of purinergic signalling
2010
Comparative study of the distribution of the α‐subunits of voltage‐gated sodium channels in normal and axotomized rat dorsal root ganglion neurons
2008
Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
2013 Standout
Phosphorylation of CBP Mediates Transcriptional Activation by Neural Activity and CaM Kinase IV
2002
Synaptic P2X receptors
2001
Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures
2017
Cbln family proteins promote synapse formation by regulating distinct neurexin signaling pathways in various brain regions
2011
Activity-Dependent IGF-1 Exocytosis Is Controlled by the Ca2+-Sensor Synaptotagmin-10
2011 StandoutNobel
A Role for the Cadherin Family of Cell Adhesion Molecules in Hippocampal Long-Term Potentiation
1998
ATP and UTP excite sensory neurons and induce CREB phosphorylation through the metabotropic receptor, P2Y2
2002
ATP regulates oligodendrocyte progenitor migration, proliferation, and differentiation: involvement of metabotropic P2 receptors
2005
Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
2014 Standout
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
A polarizing question: do M1 and M2 microglia exist?
2016
Microglial Interactions with Synapses Are Modulated by Visual Experience
2010
Origin and Functions of Tissue Macrophages
2014
Microglial Corpse Clearance: Lessons From Macrophages
2020
Genetic Dissection of Structural and Functional Components of Synaptic Plasticity. II. Fasciclin II Controls Presynaptic Structural Plasticity
1996
A Combination of Ontogeny and CNS Environment Establishes Microglial Identity
2018
Alternative Complement Pathway in Schizophrenia
2010
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Myelination and support of axonal integrity by glia
2010 Nature
Defining and using immune archetypes to classify and treat cancer
2023
Microglial dysfunction in brain aging and Alzheimer's disease
2014
Mutation in the Phosphorylation Sites of MAP Kinase Blocks Learning-Related Internalization of apCAM in Aplysia Sensory Neurons
1997 StandoutNobel
MDGAs interact selectively with neuroligin-2 but not other neuroligins to regulate inhibitory synapse development
2012 StandoutNobel
Activity of the Caenorhabditis elegans UNC-86 POU transcription factor modulates olfactory sensitivity
2003 StandoutNobel
Microglial Physiology: Unique Stimuli, Specialized Responses
2009
Siglecs as Immune Cell Checkpoints in Disease
2020
The neurexin ligands, neuroligins and leucine-rich repeat transmembrane proteins, perform convergent and divergent synaptic functions in vivo
2011 StandoutNobel
Molecular Mechanisms of Presynaptic Differentiation
2008
ATP stimulation of P2X7 receptors activates three different ionic conductances on cultured mouse Schwann cells
2001
Varicosity-Schwann Cell Interactions Mediated by ATP in the Mouse Vas Deferens
2005
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Memory Suppressor Genes: Inhibitory Constraints on the Storage of Long-Term Memory
1998 StandoutScienceNobel
RIM-Binding Protein, a Central Part of the Active Zone, Is Essential for Neurotransmitter Release
2011 StandoutScienceNobel
Microglia: Scapegoat, Saboteur, or Something Else?
2013 Science
Cholinergic and GABAergic Inputs Drive Patterned Spontaneous Motoneuron Activity before Target Contact
1999
Neural cell adhesion molecules in activity-dependent development and synaptic plasticity
1996
The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins
2011 StandoutNobel
Changing Face of Microglia
2010 Science
Rescuing impairment of long-term potentiation in fyn-deficient mice by introducing Fyn transgene
1997 StandoutNobel
Microglia Function in the Central Nervous System During Health and Neurodegeneration
2017 Standout
Dendrodendritic Inhibition in the Olfactory Bulb Is Driven by NMDA Receptors
1998
Deficiency of the Microglial Receptor CX3CR1 Impairs Postnatal Functional Development of Thalamocortical Synapses in the Barrel Cortex
2012
Modulation of three key innate immune pathways for the most common retinal degenerative diseases
2018
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
New Insights into Neuron-Glia Communication
2002 Science
Genome-wide identification of neuronal activity-regulated genes in Drosophila
2016 StandoutNobel
Surveillance, Phagocytosis, and Inflammation: How Never-Resting Microglia Influence Adult Hippocampal Neurogenesis
2014
Molecular Basis of Mechanotransduction in Living Cells
2001
Expanding APEX2 Substrates for Proximity‐Dependent Labeling of Nucleic Acids and Proteins in Living Cells
2019
Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia
1998 StandoutNobel
The Complement System in Schizophrenia
2008
HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells
2011
Imaging the glycome
2008 StandoutNobel
Microbiome–microglia connections via the gut–brain axis
2018
Alteration of Stimulus-Specific Guard Cell Calcium Oscillations and Stomatal Closing in Arabidopsis det3 Mutant
2000 StandoutScienceNobel
PSA–NCAM Is Required for Activity-Induced Synaptic Plasticity
1996
Homeostatic and injury‐induced microglia behavior in the aging brain
2013
Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal
2012 StandoutNobel
Purinoceptors on Neuroglia
2009
CREB: A Stimulus-Induced Transcription Factor Activated by A Diverse Array of Extracellular Signals
1999 Standout
Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion
2000 StandoutScienceNobel
Neurone‐to‐astrocyte communication by endogenous ATP in mixed culture of rat hippocampal neurones and astrocytes
2003
Myelination: An Overlooked Mechanism of Synaptic Plasticity?
2005
Genetic evidence for a protein-kinase-A-mediated presynaptic component in NMDA-receptor-dependent forms of long-term synaptic potentiation
2005 StandoutNobel
Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses
1999 StandoutNobel
Physiology of Microglia
2011 Standout
Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses
2012 StandoutNobel
Macrophages: Gatekeepers of Tissue Integrity
2013
Works of Beth Stevens being referenced
Complement and microglia mediate early synapse loss in Alzheimer mouse models
2016 StandoutScience
Enhanced synaptic connectivity and epilepsy in C1q knockout mice
2010
Schizophrenia risk from complex variation of complement component 4
2016 StandoutNature
Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts
2016
Microglia function during brain development: New insights from animal models
2014
Activity-dependent regulation of N-cadherin in DRG neurons: Differential regulation of N-cadherin, NCAM, and L1 by distinct patterns of action potentials
1997
ComplementC3-Deficient Mice Fail to Display Age-Related Hippocampal Decline
2015
Microglia emerge as central players in brain disease
2017
NGF and LIF both regulate galanin gene expression in primary DRG cultures
1998
Astrocytes Promote Myelination in Response to Electrical Impulses
2006
Microglia: Dynamic Mediators of Synapse Development and Plasticity
2015
The “quad‐partite” synapse: Microglia‐synapse interactions in the developing and mature CNS
2012
Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes
2018
CD47 Protects Synapses from Excess Microglia-Mediated Pruning during Development
2018
Adenosine: an activity-dependent axonal signal regulating MAP kinase and proliferation in developing Schwann cells
2004
The Classical Complement Cascade Mediates CNS Synapse Elimination
2007 Standout
The Role of Microglia in the Healthy Brain: Figure 1.
2011
Phagocytic glial cells: sculpting synaptic circuits in the developing nervous system
2013
Adenosine
2002
The complement cascade: Yin–Yang in neuroinflammation – neuro‐protection and ‐degeneration
2008
The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development
2015
Neuron-Astrocyte Signaling in the Development and Plasticity of Neural Circuits
2008
Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma
2011
NS21: Re-defined and modified supplement B27 for neuronal cultures
2008
Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner
2012 Standout
Control of Myelination by Specific Patterns of Neural Impulses
1998
The Complement System: An Unexpected Role in Synaptic Pruning During Development and Disease
2012
Regulated Expression of the Neural Cell Adhesion Molecule L1 by Specific Patterns of Neural Impulses
1995 Science
Response of Schwann Cells to Action Potentials in Development
2000 Science
Synapse elimination during development and disease: immune molecules take centre stage
2010
New insights on the role of microglia in synaptic pruning in health and disease
2015
Action Potential-Dependent Regulation of Gene Expression: Temporal Specificity in Ca2+, cAMP-Responsive Element Binding Proteins, and Mitogen-Activated Protein Kinase Signaling
1997
Cross‐Talk between Growth Factor and Purinergic Signalling Regulates Schwann Cell Proliferation
2006
Microglial transglutaminase-2 drives myelination and myelin repair via GPR56/ADGRG1 in oligodendrocyte precursor cells
2018
Microglia contribute to circuit defects in Mecp2 null mice independent of microglia-specific loss of Mecp2 expression
2016