Citation Impact
Citing Papers
Multi-Institutional Randomized Phase II Trial of Gefitinib for Previously Treated Patients With Advanced Non–Small-Cell Lung Cancer
2003 Standout
Orientation-specific responses to sustained uniaxial stretching in focal adhesion growth and turnover
2013
Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
2017 StandoutNobel
Systemic Delivery of Microencapsulated 3-Bromopyruvate for the Therapy of Pancreatic Cancer
2014 StandoutNobel
Specific Cross-talk between Epidermal Growth Factor Receptor and Integrin αvβ5 Promotes Carcinoma Cell Invasion and Metastasis
2009
Signal transduction by focal adhesion kinase in cancer
2009
Cancer–stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis, and metastasis
2012 StandoutNobel
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability
2005 StandoutNobel
Calcium-Oxidant Signaling Network Regulates AMP-activated Protein Kinase (AMPK) Activation upon Matrix Deprivation
2016
Treatment of kidney cancer
2009 StandoutNobel
Designed TPR Modules as Novel Anticancer Agents
2008
Design, Synthesis, and Biological Evaluation of Hydroquinone Derivatives of 17-Amino-17-demethoxygeldanamycin as Potent, Water-Soluble Inhibitors of Hsp90
2006
Synthesis and biological activities of novel 17-aminogeldanamycin derivatives
2004
Phosphorylation of ETS1 by Src Family Kinases Prevents Its Recognition by the COP1 Tumor Suppressor
2014 StandoutNobel
Hsp90 Regulates a von Hippel Lindau-independent Hypoxia-inducible Factor-1α-degradative Pathway
2002
Targetable HPMA Copolymer–Aminohexylgeldanamycin Conjugates for Prostate Cancer Therapy
2009
Cell–matrix adhesion
2007
A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors
2013 Standout
The von Hippel–Lindau tumour suppressor protein: O2 sensing and cancer
2008 StandoutNobel
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Integrins in cancer: biological implications and therapeutic opportunities
2009 Standout
Geldanamycin induces mitotic catastrophe and subsequent apoptosis in human glioma cells
2004
Natural products: An evolving role in future drug discovery
2011 Standout
Calcineurin Promotes Hypoxia-inducible Factor 1α Expression by Dephosphorylating RACK1 and Blocking RACK1 Dimerization
2007 StandoutNobel
Treatment of Obesity with Celastrol
2015 Standout
Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments
2015
Celastrols as Inducers of the Heat Shock Response and Cytoprotection
2004 Standout
A Versatile Palladium/Triphosphane System for Direct Arylation of Heteroarenes with Chloroarenes at Low Catalyst Loading
2010
Effects of extracellular matrix viscoelasticity on cellular behaviour
2020 StandoutNature
Heat shock protein 90: The cancer chaperone
2007
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Palladium‐Catalyzed Cross‐Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize
2012 Standout
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Protein Kinase InhibitorsThe Tyrosine-Specific Protein Kinases
1998
Natural products to drugs: natural product-derived compounds in clinical trials
2008 Standout
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Failure to prolyl hydroxylate hypoxia‐inducible factor α phenocopies VHL inactivation in vivo
2006 StandoutNobel
Natural Product Hybrids as New Leads for Drug Discovery
2003 Standout
RACK1 Competes with HSP90 for Binding to HIF-1α and Is Required for O2-Independent and HSP90 Inhibitor-Induced Degradation of HIF-1α
2007 StandoutNobel
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Hindered Aryllithium Reagents as Partners in Palladium‐Catalyzed Cross‐Coupling: Synthesis of Tri‐ and Tetra‐ortho‐Substituted Biaryls under Ambient Conditions
2013 StandoutNobel
Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives
2010 Standout
Engineered Biosynthesis of Geldanamycin Analogs for Hsp90 Inhibition
2004
Geldanamycin inhibits migration of glioma cells in vitro: A potential role for hypoxia‐inducible factor (HIF‐1α) in glioma cell invasion
2003
Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition
2016 StandoutNobel
The von Hippel–Lindau protein, HIF hydroxylation, and oxygen sensing
2005 StandoutNobel
The Cross‐Dehydrogenative Coupling of CH Bonds: A Versatile Strategy for CC Bond Formations
2013 Standout
Inhibitors of the HSP90 Molecular Chaperone: Current Status
2006
Natural products to drugs: natural product derived compounds in clinical trials
2005
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Synthesis and evaluation of geldanamycin-estradiol hybrids
1999
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Implantation and the placenta: key pieces of the development puzzle
1994 StandoutScience
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
Spermidine/Spermine N1-Acetyltransferase-1 Binds to Hypoxia-inducible Factor-1α (HIF-1α) and RACK1 and Promotes Ubiquitination and Degradation of HIF-1α
2007 StandoutNobel
Crystal Structure and Molecular Modeling of 17-DMAG in Complex with Human Hsp90
2003
Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
2016 StandoutNobel
3d Transition Metals for C–H Activation
2018 Standout
Synergistic Antipancreatic Tumor Effect by Simultaneously Targeting Hypoxic Cancer Cells With HSP90 Inhibitor and Glycolysis Inhibitor
2008
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Palladiumkatalysierte Kreuzkupplungen: eine historische Perspektive im Kontext der Nobel‐Preise 2010
2012
Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope
2011 Standout
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Identification of cell-surface heparin/heparan sulfate-binding proteins of a human uterine epithelial cell line (RL95).
1992
Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression
2007
Functional Oligothiophenes: Molecular Design for Multidimensional Nanoarchitectures and Their Applications
2009 Standout
Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation
2013
Synthesis and characterization of HPMA copolymer–aminopropylgeldanamycin conjugates
2001
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
New iminophosphorane-mediated synthesis of thieno[3′,2′:4,5]thieno[3,2-d]pyrimidin-4(3H)-ones and 5H-2,3-dithia-5,7-diaza-cyclopenta[c,d]indenes
2008
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
The von Hippel-Lindau Tumor Suppressor Protein and Clear Cell Renal Carcinoma
2007 StandoutNobel
Microwave-based synthesis of novel thienopyrimidine bioisosteres of gefitinib
2007
Induction of a heat shock factor 1-dependent stress response alters the cytotoxic activity of hsp90-binding agents.
2000
Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity.
2003
Visible‐Light Photocatalysis: Does It Make a Difference in Organic Synthesis?
2018 Standout
Transition Metal-Catalyzed C–H Amination: Scope, Mechanism, and Applications
2017 Standout
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Construction of Covalent Organic Framework for Catalysis: Pd/COF-LZU1 in Suzuki–Miyaura Coupling Reaction
2011 Standout
Recent Developments in the Maytansinoid Antitumor Agents
2004
Works of Beth Cooper being referenced
Inhibition of the oncogene product p185erbB-2 in vitro and in vivo by geldanamycin and dihydrogeldanamycin derivatives
1995
erbB-2 oncogene inhibition by geldanamycin derivatives: synthesis, mechanism of action, and structure-activity relationships
1995
Cellular Characterization of a Novel Focal Adhesion Kinase Inhibitor
2007
Design and SAR of thienopyrimidine and thienopyridine inhibitors of VEGFR-2 kinase activity
2003
Cross-Coupling Methods for the Large-Scale Preparation of an Imidazole−Thienopyridine: Synthesis of [2-(3-Methyl-3H-imidazol-4-yl)- thieno[3,2-b]pyridin-7-yl]-(2-methyl-1H-indol-5-yl)-amine
2003