Citation Impact
Citing Papers
Precise and Heritable Genome Editing in Evolutionarily Diverse Nematodes Using TALENs and CRISPR/Cas9 to Engineer Insertions and Deletions
2013 StandoutNobel
Chromosomal reinsertion of broken RSS ends during T cell development
2007
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
Telomere Dysfunction and DNA-PKcs Deficiency: Characterization and Consequence
2009
ATM Activation by Oxidative Stress
2010 Science
MDC1: The art of keeping things in focus
2010
Alternative pathways of non-homologous end joining (NHEJ) in genomic instability and cancer
2013
Hypoxia‐inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype
2016 StandoutNobel
Classical and Alternative End-Joining Pathways for Repair of Lymphocyte-Specific and General DNA Double-Strand Breaks
2012
Evolution of the Immunoglobulin Heavy Chain Class Switch Recombination Mechanism
2007
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Hif-2α is not essential for cell-autonomous hematopoietic stem cell maintenance
2013 StandoutNobel
PAXX promotes KU accumulation at DNA breaks and is essential for end-joining in XLF-deficient mice
2017
Chromatin Reader Brd4 Functions in Ig Class Switching as a Repair Complex Adaptor of Nonhomologous End-Joining
2014 StandoutNobel
More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance
2011
Gender medicine and oncology: report and consensus of an ESMO workshop
2019
MYC on the Path to Cancer
2012 Standout
Mechanisms of Programmed DNA Lesions and Genomic Instability in the Immune System
2013
DNA-PKcs and ATM co-regulate DNA double-strand break repair
2009
Catalytic and Noncatalytic Roles of the CtIP Endonuclease in Double-Strand Break End Resection
2014
Playing the End Game: DNA Double-Strand Break Repair Pathway Choice
2012
Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
2011 StandoutNobel
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Accessibility of chromosomal recombination breaks in nuclei of wild-type and DNA-PKcs-deficient cells
2009
Identification of Early Replicating Fragile Sites that Contribute to Genome Instability
2013
Cancer stem cells revisited
2017 Standout
Regulation of DNA double-strand break repair pathway choice
2007
Interaction between microbiota and immunity in health and disease
2020 Standout
ROS Function in Redox Signaling and Oxidative Stress
2014 Standout
The Histone Chaperone Spt6 Is Required for Activation-induced Cytidine Deaminase Target Determination through H3K4me3 Regulation
2012 StandoutNobel
Sex and gender: modifiers of health, disease, and medicine
2020 Standout
Proteolytic Control of the Oncoprotein Transcription Factor Myc
2011
DNA Damage, Aging, and Cancer
2009 Standout
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Multiple functions of MRN in end-joining pathways during isotype class switching
2009
Differential Phosphorylation of DNA-PKcs Regulates the Interplay between End-Processing and End-Ligation during Nonhomologous End-Joining
2015
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
2010 Standout
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Lymphocyte-Specific Compensation for XLF/Cernunnos End-Joining Functions in V(D)J Recombination
2008
Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer
2008
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Defined in Vitro System
2014 StandoutNobel
B cell–specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers
2009 StandoutNobel
The ATM protein kinase and cellular redox signaling: beyond the DNA damage response
2011
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
2015 Standout
End-joining, translocations and cancer
2013
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
The In Vivo Pattern of Binding of RAG1 and RAG2 to Antigen Receptor Loci
2010
Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability
2016 StandoutNobel
Regulation of c-Myc Ubiquitination Controls Chronic Myelogenous Leukemia Initiation and Progression
2013
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
Pathways that suppress programmed DNA breaks from progressing to chromosomal breaks and translocations
2006
53BP1 facilitates long-range DNA end-joining during V(D)J recombination
2008 Nature
Clinical relevance of tumour-associated macrophages
2022
Ablation of Fbxw7 Eliminates Leukemia-Initiating Cells by Preventing Quiescence
2013
AMPK: a nutrient and energy sensor that maintains energy homeostasis
2012 Standout
The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator
2012 StandoutNobel
Mechanisms and Implications of Metabolic Heterogeneity in Cancer
2019
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
2012 StandoutNobel
Carboxy-terminal domain of AID required for its mRNA complex formation in vivo
2009 StandoutNobel
Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1)
2012
Serine Synthesis Helps Hypoxic Cancer Stem Cells Regulate Redox
2016 StandoutNobel
AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements
2007 StandoutNobel
Mechanisms of double-strand break repair in somatic mammalian cells
2009
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
2015 StandoutNobel
Therapeutic Targeting of the Tumor Microenvironment
2021
Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
2016 StandoutScience
AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination
2009 StandoutNobel
An Evolutionary View of the Mechanism for Immune and Genome Diversity
2012 StandoutNobel
The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination
2009 StandoutNobel
megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering
2013 StandoutNobel
Metabolic reprogramming and cancer progression
2020 StandoutScience
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
Restoration of ATM Expression in DNA-PKcs–Deficient Cells Inhibits Signal End Joining
2016
Simultaneous precise editing of multiple genes in human cells
2019 StandoutNobel
Ionizing Radiation Selectively Reduces Skin Regulatory T Cells and Alters Immune Function
2014 StandoutNobel
An Erythroid Enhancer of BCL11A Subject to Genetic Variation Determines Fetal Hemoglobin Level
2013 Science
Dissociation of in vitro DNA deamination activity and physiological functions of AID mutants
2008 StandoutNobel
Mechanism and Regulation of Class Switch Recombination
2008
V(D)J Recombination: Mechanisms of Initiation
2011
Functional Intersection of ATM and DNA-Dependent Protein Kinase Catalytic Subunit in Coding End Joining during V(D)J Recombination
2013
Evolutionary Comparison of the Mechanism of DNA Cleavage with Respect to Immune Diversity and Genomic Instability
2012 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination
2010 StandoutNobel
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
2016 StandoutNobel
Works of Beth A. Helmink being referenced
MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks
2009
H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes
2010 Nature
Regulation of hematopoietic stem cell differentiation by a single ubiquitin ligase–substrate complex
2010
The Influence of the Gut Microbiome on Cancer, Immunity, and Cancer Immunotherapy
2018
Formation of Dynamic γ-H2AX Domains along Broken DNA Strands Is Distinctly Regulated by ATM and MDC1 and Dependent upon H2AX Densities in Chromatin
2009
Modulating the microbiome to improve therapeutic response in cancer
2019
The microbiome, cancer, and cancer therapy
2019
ATM stabilizes DNA double-strand-break complexes during V(D)J recombination
2006 Nature
The Response to and Repair of RAG-Mediated DNA Double-Strand Breaks
2012
Histone H2AX stabilizes broken DNA strands to suppress chromosome breaks and translocations during V(D)J recombination
2009
LYVE1+ macrophages of murine peritoneal mesothelium promote omentum-independent ovarian tumor growth
2021