Citation Impact
Citing Papers
Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
The Human Multidrug Resistance Protein MRP5 Transports Folates and Can Mediate Cellular Resistance against Antifolates
2005
Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression
2019 Standout
Increased Photosensitivity in HL60 Cells Expressing Wild‐Type p53
1997
NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer
2009 Standout
Postoperative Irradiation with or without Concomitant Chemotherapy for Locally Advanced Head and Neck Cancer
2004 Standout
Photodynamic Therapy
1998 Standout
Perspectives on cancer therapy-induced mucosal injury
2004 Standout
Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
2004 Standout
Mechanisms and insights into drug resistance in cancer
2013
Flexible regression models with cubic splines
1989 Standout
Dose calculation of anticancer drugs: a review of the current practice and introduction of an alternative.
1996 Standout
High-dose methotrexate: a critical reappraisal.
1987
Cancer drug resistance: an evolving paradigm
2013 Standout
Head and neck cancer
2008 Standout
Nanoparticle therapeutics: an emerging treatment modality for cancer
2008 Standout
Synthesis and biological activity of analogues of diazaquinomycin A, a new thymidylate synthase inhibitor.
1989 StandoutNobel
Modulation of oxidative stress as an anticancer strategy
2013 Standout
GLIA: A novel drug discovery target for clinical pain
2003
Anticancer activities of histone deacetylase inhibitors
2006 Standout
Dysfunctional KEAP1–NRF2 Interaction in Non-Small-Cell Lung Cancer
2006 Standout
Anticancer activity of the lanthanum compound [tris(1,10-phenanthroline)lanthanum(III)]trithiocyanate (KP772; FFC24)
2005
Targeting multidrug resistance in cancer
2006 Standout
Chemotherapy and the war on cancer
2005 Standout
Transcriptional activation of p21WAF1by PTEN/MMAC1 tumr suppressor
2000
Structure and energetics of ligand binding to proteins: Escherichia coli dihydrofolate reductase‐trimethoprim, a drug‐receptor system
1988 Standout
Persistent postsurgical pain: risk factors and prevention
2006 Standout
The Endoplasmic Reticulum Chaperone Glycoprotein GRP94 with Ca2+-binding and Antiapoptotic Properties Is a Novel Proteolytic Target of Calpain during Etoposide-induced Apoptosis
1999
Determination of methotrexate in environmental samples by solid phase extraction and high performance liquid chromatography: ultraviolet or tandem mass spectrometry detection?
2000
Head and Neck Cancer
1993 Standout
5-Fluorouracil: mechanisms of action and clinical strategies
2003 Standout
Production of catecholamines in the human epidermis
1992
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
2006 Standout
Astrocyte–endothelial interactions at the blood–brain barrier
2005 Standout
The Glut athione S-Transferase Supergene Family: Regulation of GST and the Contribution of the lsoenzymes to Cancer Chemoprotection and Drug Resistance Part I
1995 Standout
Clinical Pharmacology of 5-Fluorouracil
1989 Standout
Prevention of Second Primary Tumors with Isotretinoin in Squamous-Cell Carcinoma of the Head and Neck
1990 Standout
Neuropathic Pain Activates the Endogenous κ Opioid System in Mouse Spinal Cord and Induces Opioid Receptor Tolerance
2004 StandoutNobel
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Adjuvant chemotherapy for high-risk squamous-cell carcinoma of the head and neck.
1987
Antineoplastic Drugs
1978
6 Recent Progress in the Medicinal Chemistry of 2,4-Diaminopyrimidines
1982
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
New Approaches to Cancer Chemotherapy with Methotrexate
1975
Diagnosis and treatment of leptomeningeal metastases from solid tumors: Experience with 90 patients
1982 Standout
Graphene Oxide: Preparation, Functionalization, and Electrochemical Applications
2012 Standout
Changing role of chemotherapy in treatment of head and neck cancer
1982
Synthesis and Function of 3-Phosphorylated Inositol Lipids
2001 Standout
Chemotherapy in Head and Neck Cancer
1983
5-Fluorouracil Incorporated into DNA Is Excised by the Smug1 DNA Glycosylase to Reduce Drug Cytotoxicity
2007 StandoutNobel
7-Hydroxymethotrexate as a urinary metabolite in human subjects and rhesus monkeys receiving high dose methotrexate.
1976
THE EFFECT OF AMETHOPTERIN ON THE IMMUNE RESPONSE*
1971 StandoutNobel
The Pharmacology and Clinical Use of Methotrexate
1983
Methotrexate: clinical pharmacology, current status and therapeutic guidelines
1977
Quinazoline antifolates with dual biochemical loci of action. Biochemical and biological studies directed towards overcoming methotrexate resistance
1980
The Effect of Adjuvant Chemotherapy on Relapse-Free Survival in Patients with Osteosarcoma of the Extremity
1986 Standout
Immunosuppressive Effects of Cytosine Arabinoside and Methotrexate in Man
1969
Diazaquinomycin A, a new antifolate antibiotic, inhibits thymidylate synthase.
1985 StandoutNobel
The Calpain System
2003 Standout
The reversal of methotrexate cytotoxicity to mouse bone marrow cells by leucovorin and nucleosides.
1976
Identification of Major Prognostic Subgroups of Patients with Large-Cell Lymphoma Treated with m-BACOD or M-BACOD
1986
Lanthanum Chloride Inhibits LPS Mediated Expressions of Pro-Inflammatory Cytokines and Adhesion Molecules in HUVECs: Involvement of NF-κB-Jmjd3 Signaling
2017 Standout
Dihydrofolate reductase inhibitors as potential drugs
1981
Histone Deacetylase Inhibitors Radiosensitize Human Melanoma Cells by Suppressing DNA Repair Activity
2005
Mechanisms of Cancer Drug Resistance
2002 Standout
Chemotherapy for the Treatment of Patients with Metastatic Colorectal Cancer: An Overview
1997
Structural and Biochemical Studies of a Fluoroacetyl-CoA-Specific Thioesterase Reveal a Molecular Basis for Fluorine Selectivity
2010 StandoutNobel
Randomized Trial of Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy Versus Systemic Chemotherapy and Palliative Surgery in Patients With Peritoneal Carcinomatosis of Colorectal Cancer
2003 Standout
Electrochemical Sensor for Ultrasensitive Determination of Doxorubicin and Methotrexate Based on Cyclodextrin‐Graphene Hybrid Nanosheets
2011
Pharmaceuticals of Emerging Concern in Aquatic Systems: Chemistry, Occurrence, Effects, and Removal Methods
2019 Standout
Threshold Methotrexate Concentration for In Vivo Inhibition of DNA Synthesis in Normal and Tumorous Target Tissues
1973
Molecular mechanisms of drug resistance
1990
Methotrexate pneumonitis induced by intrathecal methotrexate therapy.A case report with pharmacokinetic data
1976
Teratomas in Infancy and Childhood
1983 Standout
Drug Resistance in Cancer: An Overview
2014 Standout
Cytoreductive Surgery Combined With Perioperative Intraperitoneal Chemotherapy for the Management of Peritoneal Carcinomatosis From Colorectal Cancer: A Multi-Institutional Study
2004 Standout
High dose methotrexate with and without BCG therapy in advanced head and neck malignancy
1979
Drug Resistance in Leishmaniasis
2006 Standout
Effect of human renal and hepatic disease on the pharmacokinetics of anticancer drugs
1982
Time limitations in the reversal by citrovorum factor of methotrexate-induced immunosuppression in mice
1977
Effect of acyclovir on various murine in vivo and in vitro immunologic assay systems
1982 StandoutNobel
Cisplatin
1984 Standout
Adjuvant Methotrexate and Citrovorum-Factor Treatment of Osteogenic Sarcoma
1974
Preventing and Managing Toxicities of High-Dose Methotrexate
2016 Standout
Works of Bertino being referenced
Detection of Monoclonal Lymphoid Subpopulations in Clinical Specimens by Pcr and Conformational Polymorphisms of Crna Molecules
1992
Current understanding of methotrexate pharmacology and efficacy in acute leukemias. Use of newer antifolates in clinical trials.
2001
Effectiveness of high-dose infusions of methotrexate followed by leucovorin in carcinoma of the head and neck.
1968
Methotrexate and 5-fluorouracil in sequence in squamous head and neck cancer.
1983
Approaches to drug selectivity in cancer therapy on the basis of differences between membranes of normal vs. neoplastic cells.
1980
Improved therapeutic index of methotrexate with "leucovorin rescue".
1973
Head and neck cancer. 3. Toxicity of 24-hour infusions of methotrexate (NSC-740) and protection by leucovorin (NSC-3590) in patients with epidermoid carcinomas.
1967
Clinical and pharmacological evaluation of triazinate in humans.
1976
TECHNIQUES FOR STUDY OF RESISTANCE TO FOLIC ACID ANTAGONISTS.
1964
Pretreatment of endometrial carcinoma cell lines with butyrate results in upregulation of Bax and correlates with potentiation of radiation induced cell kill.
2001
Transfection of wild-type but not mutant p53 induces early monocytic differentiation in HL60 cells and increases their sensitivity to stress.
1995
Sequential methotrexate and 5-fluorouracil: mechanisms of synergy.
1983