Citation Impact
Citing Papers
Visualizing enveloping layer glycans during zebrafish early embryogenesis
2010 StandoutNobel
Probing mucin-type O-linked glycosylation in living animals
2006 StandoutNobel
A Gene Network Regulating Lysosomal Biogenesis and Function
2009 StandoutScience
Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O 2 activation
2019 StandoutNobel
Single Reconstituted Neuronal SNARE Complexes Zipper in Three Distinct Stages
2012 StandoutScienceNobel
Copper-free click chemistry in living animals
2010 StandoutNobel
Sculpting conducting nanopore size and shape through de novo protein design
2024 StandoutScienceNobel
Proteomics of the lysosome
2008
A New Type of Bacterial Sulfatase Reveals a Novel Maturation Pathway in Prokaryotes
2006
Glucosamine‐6‐sulfamate Analogues of Heparan Sulfate as Inhibitors of Endosulfatases
2010
Reconstitution of Formylglycine-generating Enzyme with Copper(II) for Aldehyde Tag Conversion
2015
Sequence determinants directing conversion of cysteine to formylglycine in eukaryotic sulfatases
1999
Function and Structure of a Prokaryotic Formylglycine-generating Enzyme
2008 StandoutNobel
The N-terminal Domain of a Glycolipid-anchored Prion Protein Is Essential for Its Endocytosis via Clathrin-coated Pits
1995
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Mammalian Prion Biology
2004
Chemical Technologies for Probing Glycans
2006 StandoutNobel
Copper Binding to the Octarepeats of the Prion Protein
2003
Sulfatases: Structure, Mechanism, Biological Activity, Inhibition, and Synthetic Utility
2004
An Internalization Motif Is Created in the Cytoplasmic Domain of the Transferrin Receptor by Substitution of a Tyrosine at the First Position of a Predicted Tight Turn
1995
Coupling of Coat Assembly and Vesicle Budding to Packaging of Putative Cargo Receptors
1999 StandoutNobel
Mapping Cu(II) Binding Sites in Prion Proteins by Diethyl Pyrocarbonate Modification and Matrix-assisted Laser Desorption Ionization-Time of Flight (MALDI-TOF) Mass Spectrometric Footprinting
2002
Cofactor-independent oxidases and oxygenases
2010
Copper Stimulates Endocytosis of the Prion Protein
1998
Lack of prion protein expression results in a neuronal phenotype sensitive to stress
2001
Introducing genetically encoded aldehydes into proteins
2007 StandoutNobel
Mannose 6-Phosphate Receptor Targeting and its Applications in Human Diseases
2007
Molecular Advances in Understanding Inherited Prion Diseases
2002
Toxicity of novel C‐terminal prion protein fragments and peptides harbouring disease‐related C‐terminal mutations
2001
Copper and zinc cause delivery of the prion protein from the plasma membrane to a subset of early endosomes and the Golgi
2003
Metal ions and prion diseases
2002
No Superoxide Dismutase Activity of Cellular Prion Protein in vivo
2003
The Multiple Sulfatase Deficiency Gene Encodes an Essential and Limiting Factor for the Activity of Sulfatases
2003
Cellular prion protein function in copper homeostasis and redox signalling at the synapse
2003
Sulfotransferases and Sulfatases in Mycobacteria
2002 StandoutNobel
Potent active site-directed inhibition of steroid sulphatase by tricyclic coumarin-based sulphamates
2000
Antioxidant activity related to copper binding of native prion protein
2001
Direct Evidence for ArOS Bond Cleavage upon Inactivation of Pseudomonas aeruginosa Arylsulfatase by Aryl Sulfamates
2008
Chemoselective modification of proteins: hitting the target
2008
Copper binding to octarepeat peptides of the prion protein monitored by mass spectrometry
2000
Saturation of the Endocytic Pathway for the Transferrin Receptor Does Not Affect the Endocytosis of the Epidermal Growth Factor Receptor
1997 StandoutNobel
Sulfotransferases: Structure, Mechanism, Biological Activity, Inhibition, and Synthetic Utility
2004
Riding the sulfur cycle – metabolism of sulfonates and sulfate esters in Gram-negative bacteria
2000
The NPXY internalization signal of the LDL receptor adopts a reverse-turn conformation
1991
Brain Copper Content and Cuproenzyme Activity Do Not Vary with Prion Protein Expression Level
2000
Molecular Evolution of the Mammalian Prion Protein
2003
Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel
1995
Biological inorganic and bioinorganic chemistry of neurodegeneration based on prion and Alzheimer diseases
2004
Cellular Trafficking of G Protein-coupled Receptor/β-Arrestin Endocytic Complexes
1999
Copper(II) complexes of peptide fragments of the prion protein. Conformation changes induced by copper(II) and the binding motif in C-terminal protein region
2003
Glycosylation in health and disease
2019
TGN38 is maintained in the trans-Golgi network by a tyrosine-containing motif in the cytoplasmic domain.
1993
Effect of metal ions on de novo aggregation of full-length prion protein
2004
Probing Copper2+ Binding to the Prion Protein Using Diamagnetic Nickel2+ and 1H NMR: The Unstructured N terminus Facilitates the Coordination of Six Copper2+ Ions at Physiological Concentrations
2005
Chemoselective Ligation and Modification Strategies for Peptides and Proteins
2008
Consequences of manganese replacement of copper for prion protein function and proteinase resistance
2000
Mycobacterium tuberculosis Rv3406 Is a Type II Alkyl Sulfatase Capable of Sulfate Scavenging
2013 StandoutNobel
Chemistry in living systems
2005 StandoutNobel
Ionic Strength and Transition Metals Control PrPSc Protease Resistance and Conversion-inducing Activity
2004
Distinct Saturable Pathways for the Endocytosis of Different Tyrosine Motifs
1998 StandoutNobel
The cellular prion protein binds copper in vivo
1997 Nature
Site-specific chemical protein conjugation using genetically encoded aldehyde tags
2012 StandoutNobel
Mannose 6-phosphate receptors: new twists in the tale
2003
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Copper Chelation Delays the Onset of Prion Disease
2003
Building Better Barrels – β-barrel Biogenesis and Insertion in Bacteria and Mitochondria
2021
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Generating aldehyde-tagged antibodies with high titers and high formylglycine yields by supplementing culture media with copper(II)
2016
Sulfatases and sulfatase modifying factors: an exclusive and promiscuous relationship
2005
Cell Surface Expression of the Prion Protein in Yeast Does Not Alter Copper Utilization Phenotypes
2004
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
Bioluminescent Probes of Sulfatase Activity
2010 StandoutNobel
Preferential Cu2+ Coordination by His96 and His111 Induces β-Sheet Formation in the Unstructured Amyloidogenic Region of the Prion Protein
2004
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Novel cofactors via post-translational modifications of enzyme active sites
2000
Formylglycine Aldehyde Tag—Protein Engineering through a Novel Post‐translational Modification
2009
1.3 Å Structure of Arylsulfatase from Pseudomonas aeruginosa Establishes the Catalytic Mechanism of Sulfate Ester Cleavage in the Sulfatase Family
2001
Intrinsically unstructured proteins evolve by repeat expansion
2003
NMR structures of three single-residue variants of the human prion protein
2000 StandoutNobel
Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains
2013 StandoutNobel
The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na + channels
2004 StandoutNobel
In Vivo Imaging of Membrane-Associated Glycans in Developing Zebrafish
2008 StandoutScienceNobel
Lassa virus entry requires a trigger-induced receptor switch
2014 Science
Ligand-induced endocytosis of epidermal growth factor receptors that are defective in binding adaptor proteins.
1995
Structural Basis for Copper–Oxygen Mediated C−H Bond Activation by the Formylglycine‐Generating Enzyme
2017
New Aldehyde Tag Sequences Identified by Screening Formylglycine Generating Enzymes in Vitro and in Vivo
2008 StandoutNobel
Normal prion protein has an activity like that of superoxide dismutase
1999
Copper-free click chemistry for dynamic in vivo imaging
2007 StandoutNobel
A Flexible Route to Mannose 6-Phosphonate Functionalized Derivatives
2002
ENDOCYTOSIS AND MOLECULAR SORTING
1996
The Alzheimer's Disease Amyloid Precursor Protein Modulates Copper-Induced Toxicity and Oxidative Stress in Primary Neuronal Cultures
1999
Targeted metabolic labeling of yeast N-glycans with unnatural sugars
2010 StandoutNobel
Molecular Features of the Copper Binding Sites in the Octarepeat Domain of the Prion Protein
2002
Coat Proteins and Vesicle Budding
1996 StandoutScienceNobel
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Copper is a Cofactor of the Formylglycine‐Generating Enzyme
2016
Anaerobic Sulfatase-Maturating Enzymes: Radical SAM Enzymes Able To Catalyze in Vitro Sulfatase Post-translational Modification
2007
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag
2009 StandoutNobel
Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity
2000 StandoutNobel
SULFATASES AND HUMAN DISEASE
2005
Imaging bacterial peptidoglycan with near-infrared fluorogenic azide probes
2014 StandoutNobel
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence
2003 StandoutNobel
A Pictet-Spengler ligation for protein chemical modification
2012 StandoutNobel
A fluorogenic substrate for the continuous assaying of aryl sulfatases
2005
Prions
1998 StandoutNobel
NMR solution structure of the human prion protein
2000 StandoutNobel
CLATHRIN-COATED VESICLE FORMATION AND PROTEIN SORTING: An Integrated Process
1997
Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors.
1993
Protein Sorting by Transport Vesicles
1996 StandoutScienceNobel
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Formylglycine, a Post-Translationally Generated Residue with Unique Catalytic Capabilities and Biotechnology Applications
2014 StandoutNobel
Copper Binding in the Prion Protein
2004
Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains
1996 StandoutNobel
Crystal Structure of Human Arylsulfatase A: The Aldehyde Function and the Metal Ion at the Active Site Suggest a Novel Mechanism for Sulfate Ester Hydrolysis,
1998
Evidence of Presynaptic Location and Function of the Prion Protein
1999
Chemoselektive Ligations‐ und Modifikationsstrategien für Peptide und Proteine
2008
Escherichia coli K1 aslA Contributes to Invasion of Brain Microvascular Endothelial Cells In Vitro and In Vivo
2000
Imaging the glycome
2008 StandoutNobel
Recruitment of epidermal growth factor and transferrin receptors into coated pits in vitro: differing biochemical requirements.
1993
The insulin receptor juxtamembrane region contains two independent tyrosine/beta-turn internalization signals.
1992
NMR structure of the bovine prion protein
2000 StandoutNobel
Copper Coordination in the Full-Length, Recombinant Prion Protein
2003 Nobel
Recombinant prion protein does not possess SOD-1 activity
2005
Copper induces increased beta-sheet content in the scrapie-susceptible ovine prion protein PrPVRQ compared with the resistant allelic variant PrPARR
2004
Nucleation of COPII Vesicular Coat Complex by Endoplasmic Reticulum to Golgi Vesicle SNAREs
1998 StandoutScienceNobel
Protein Glycoengineering Enabled by the Versatile Synthesis of Aminooxy Glycans and the Genetically Encoded Aldehyde Tag
2011 StandoutNobel
Systemic inflammation and neurodegeneration in a mouse model of multiple sulfatase deficiency
2007
Folate receptors targeted to clathrin-coated pits cannot regulate vitamin uptake.
1995
In vitro binding of clathrin adaptors to sorting signals correlates with endocytosis and basolateral sorting.
1996
Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
2005
COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform
1997 StandoutNobel
YTRF is the conserved internalization signal of the transferrin receptor, and a second YTRF signal at position 31-34 enhances endocytosis.
1993
In Vitro Reconstitution of Formylglycine‐Generating Enzymes Requires Copper(I)
2015
Folding of the C-terminal bacterial binding domain in statherin upon adsorption onto hydroxyapatite crystals
2006 StandoutNobel
The Octarepeat Domain of the Prion Protein Binds Cu(II) with Three Distinct Coordination Modes at pH 7.4
2005
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
Ultrastructural localization of prion proteins: Physiological and pathological implications
2000
Chemical Glycoproteomics
2016 StandoutNobel
Bioorthogonale Chemie – oder: in einem Meer aus Funktionalität nach Selektivität fischen
2009 StandoutNobel
Protein N-Glycosylation: Molecular Genetics and Functional Significance
1998
The tyrosine-containing internalization motif in the cytoplasmic domain of TGN38/41 lies within a nascent helix.
1994
Works of Bernhard Schmidt being referenced
A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme
2005
Proprotein Convertases Process and Thereby Inactivate Formylglycine-generating Enzyme*
2013
Rapid degradation of an active formylglycine generating enzyme variant leads to a late infantile severe form of multiple sulfatase deficiency
2013
SUMF1 mutations affecting stability and activity of formylglycine generating enzyme predict clinical outcome in multiple sulfatase deficiency
2011
Paralog of the formylglycine‐generating enzyme – retention in the endoplasmic reticulum by canonical and noncanonical signals
2008
Arylsulfatase from Klebsiella pneumoniae Carries a Formylglycine Generated from a Serine
1998
The essential tyrosine of the internalization signal in lysosomal acid phosphatase is part of a β turn
1991
A novel protein modification generating an aldehyde group in sulfatases: its role in catalysis and disease
1998
Amino Acid Residues Forming the Active Site of Arylsulfatase A
1999
The Evolutionary Conservation of a Novel Protein Modification, the Conversion of Cysteine to Serinesemialdehyde in Arylsulfatase from Volvox carteri
1996
Prion protein expression in muscle cells and toxicity of a prion protein fragment
1998
Identification of novel lysosomal matrix proteins by proteome analysis
2005
A neurotoxic prion protein fragment enhances proliferation of microglia but not astrocytes in culture
1996
The Iron Sulfur Protein AtsB Is Required for Posttranslational Formation of Formylglycine in the Klebsiella Sulfatase
1999
Molecular Characterization of the Human Cα-formylglycine-generating Enzyme
2005
Molecular Basis for Multiple Sulfatase Deficiency and Mechanism for Formylglycine Generation of the Human Formylglycine-Generating Enzyme
2005
The human SUMF1 gene, required for posttranslational sulfatase modification, defines a new gene family which is conserved from pro- to eukaryotes
2003
Expression, Localization, Structural, and Functional Characterization of pFGE, the Paralog of the Cα-Formylglycine-generating Enzyme
2005
Proteolysis of Insulin-Like Growth Factors (IGF) and IGF Binding Proteins by Cathepsin D1
1997
Posttranslational Formation of Formylglycine in Prokaryotic Sulfatases by Modification of Either Cysteine or Serine
1998
Prion Protein Binds Copper within the Physiological Concentration Range
2001
Identification of formylglycine in sulfatases by matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry
2002
ERp44 Mediates a Thiol-independent Retention of Formylglycine-generating Enzyme in the Endoplasmic Reticulum
2008
Conversion of cysteine to formylglycine in eukaryotic sulfatases occurs by a common mechanism in the endoplasmic reticulum
1998
Molecular basis of multiple sulfatase deficiency, mucolipidosis II/III and Niemann–Pick C1 disease — Lysosomal storage disorders caused by defects of non-lysosomal proteins
2008
Localization of the Insulin-like Growth Factor II Binding Site to Amino Acids 1508–1566 in Repeat 11 of the Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor
1995
Molecular cloning and primary structure of Man9‐mannosidase from human kidney
1993
Multiple Sulfatase Deficiency Is Caused by Mutations in the Gene Encoding the Human Cα-Formylglycine Generating Enzyme
2003
A presequence-binding groove in Tom70 supports import of Mdl1 into mitochondria
2015
Probing the oxygen-binding site of the human formylglycine-generating enzyme using halide ions
2007
Crystal Structure of Human pFGE, the Paralog of the Cα-formylglycine-generating Enzyme
2005
The Non-catalytic N-terminal Extension of Formylglycine-generating Enzyme Is Required for Its Biological Activity and Retention in the Endoplasmic Reticulum
2008
Characterization of Posttranslational Formylglycine Formation by Luminal Components of the Endoplasmic Reticulum
2001
Prion Protein-Deficient Cells Show Altered Response to Oxidative Stress Due to Decreased SOD-1 Activity
1997
A Prion Protein Fragment Primes Type 1 Astrocytes to Proliferation Signals from Microglia
1998
Effects of oxidative stress on prion protein expression in pc12 cells
1997
NCU-G1 is a highly glycosylated integral membrane protein of the lysosome
2009
Conversion of cysteine to formylglycine: A protein modification in the endoplasmic reticulum
1997
Genetic heterogeneity of steroid sulfatase deficiency revealed with cDNA for human steroid sulfatase
1987