Citation Impact
Citing Papers
A Decade of Molecular Studies of Fragile X Syndrome
2002
RNA tertiary interactions in the large ribosomal subunit: The A-minor motif
2001 StandoutNobel
Imaging Tetrahymena ribozyme splicing activity in single live mammalian cells
2003 StandoutNobel
Specificity of RNA–RNA helix recognition
2002 StandoutNobel
A drug-controllable tag for visualizing newly synthesized proteins in cells and whole animals
2008 StandoutNobel
Structural inference of native and partially folded RNA by high-throughput contact mapping
2008 StandoutNobel
A Genomewide Search for Ribozymes Reveals an HDV-Like Sequence in the Human CPEB3 Gene
2006 StandoutScienceNobel
Automated de novo prediction of native-like RNA tertiary structures
2007 StandoutNobel
A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing
2004
The X chromosome and fragile X mental retardation
2002
A Novel Function for Fragile X Mental Retardation Protein in Translational Activation
2009
Fragile X Mental Retardation Protein Targets G Quartet mRNAs Important for Neuronal Function
2001
Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes
2005
Structure and function of an RNase H domain at the heart of the spliceosome
2008
A Mouse Model of the Human Fragile X Syndrome I304N Mutation
2009
Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles
2004
The fragile X mental retardation protein inhibits translation via interacting with mRNA
2001
The fragile X mental retardation protein and group I metabotropic glutamate receptors regulate levels of mRNA granules in brain
2005 Nobel
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Fragile X Syndrome: Loss of Local mRNA Regulation Alters Synaptic Development and Function
2008
Transport of Fragile X Mental Retardation Protein via Granules in Neurites of PC12 Cells
2002
Phosphorylation influences the translation state of FMRP-associated polyribosomes
2003
A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins
2002
The Fragile X Syndrome Protein FMRP Associates with BC1 RNA and Regulates the Translation of Specific mRNAs at Synapses
2003
Microarray Identification of FMRP-Associated Brain mRNAs and Altered mRNA Translational Profiles in Fragile X Syndrome
2001
Fragile X Mental Retardation Protein Is Associated with Translating Polyribosomes in Neuronal Cells
2004
Mechanical Devices of the Spliceosome: Motors, Clocks, Springs, and Things
1998
The mGluR theory of fragile X mental retardation
2004
MicroRNAs
2004 Standout
Animal models of human disease: zebrafish swim into view
2007 Standout
Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome
2008
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
Metazoan stress granule assembly is mediated by P-eIF2α-dependent and -independent mechanisms
2009
A Common Core RNP Structure Shared between the Small Nucleoar Box C/D RNPs and the Spliceosomal U4 snRNP
2000 StandoutNobel
The Spliceosome: Design Principles of a Dynamic RNP Machine
2009 Standout
Suppression of Multiple Substrate Mutations by Spliceosomal prp8 Alleles Suggests Functional Correlations with Ribosomal Ambiguity Mutants
2004
Identification of mRNA/Protein (mRNP) Complexes Containing Purα, mStaufen, Fragile X Protein, and Myosin Va and their Association with Rough Endoplasmic Reticulum Equipped with a Kinesin Motor
2002
Streptomycin binds to the decoding center of 16 S ribosomal RNA 1 1Edited by M. Gottesman
1997
Structure of Functionally Activated Small Ribosomal Subunit at 3.3 Å Resolution
2000 StandoutNobel
TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins
2016 StandoutNobel
Quality control of mRNA 3′-end processing is linked to the nuclear exosome
2001 StandoutNatureNobel
RNA-binding proteins in human genetic disease
2008
Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway
2004
The U1 snRNP protein U1C recognizes the 5′ splice site in the absence of base pairing
2002 StandoutNatureNobel
The question remains: is the spliceosome a ribozyme?
2000
Protein functions in pre-mRNA splicing
1997
An SMN-Dependent U12 Splicing Event Essential for Motor Circuit Function
2012
FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
2011 Standout
New loop-loop tertiary interactions in self-splicing introns of subgroup IC and ID: a complete 3D model of the Tetrahymena thermophila ribozyme
1996
Functional interaction of a novel 15.5kD [U4/U6middle dotU5] tri-snRNP protein with the 5' stem-loop of U4 snRNA
1999
Metazoan MicroRNAs
2018 Standout
Placement of protein and RNA structures into a 5 Å-resolution map of the 50S ribosomal subunit
1999 StandoutNatureNobel
The 100-kDa U5 snRNP protein (hPrp28p) contacts the 5′ splice site through its ATPase site
2001
Genetics of human prefrontal function
2003
An RNA Switch at the 5′ Splice Site Requires ATP and the DEAD Box Protein Prp28p
1999
DEAD-box proteins: the driving forces behind RNA metabolism
2004
[2] Methylene blue-mediated cross-linking of proteins to double-stranded RNA
2000
The EF-G-like GTPase Snu114p Regulates Spliceosome Dynamics Mediated by Brr2p, a DExD/H Box ATPase
2006
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Insights into the mechanisms of splicing: more lessons from the ribosome: Figure 1.
2005
Hypersensitivity to mGluR5 and ERK1/2 Leads to Excessive Protein Synthesis in the Hippocampus of a Mouse Model of Fragile X Syndrome
2010
PP1/PP2A Phosphatases Are Required for the Second Step of Pre-mRNA Splicing and Target Specific snRNP Proteins
2006
Functional and physical interactions between components of the Prp19p-associated complex
2002
Specific Alterations of U1-C Protein or U1 Small Nuclear RNA Can Eliminate the Requirement of Prp28p, an Essential DEAD Box Splicing Factor
2001
Dendritic mRNA: transport, translation and function
2007
RNA Cargoes Associating with FMRP Reveal Deficits in Cellular Functioning in Fmr1 Null Mice
2003
Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2
2005
Drosophila Fragile X-Related Gene Regulates the MAP1B Homolog Futsch to Control Synaptic Structure and Function
2001
The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif
2001
Regulation of local mRNA translation
2004
RNA-binding proteins in human genetic disease
2020
Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs
2007
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
The Exosome: A Conserved Eukaryotic RNA Processing Complex Containing Multiple 3′→5′ Exoribonucleases
1997
A role for ubiquitin in the spliceosome assembly pathway
2008
Characterization of U4 and U6 interactions with the 5′ splice site using a S. cerevisiae in vitro trans-splicing system
2001
Biochemical mechanisms for translational regulation in synaptic plasticity
2004
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6middle dotU5] tri-snRNP
1999
Crystal structure of a hepatitis delta virus ribozyme
1998 StandoutNatureNobel
Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis
2002
Prp8 protein: At the heart of the spliceosome
2005
Mechanisms of gene silencing by double-stranded RNA
2004 StandoutNature
ATP-dependent unwinding of U4/U6 snRNAs by the Brr2 helicase requires the C terminus of Prp8
2008
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
The Fragile X Mental Retardation Protein in Circadian Rhythmicity and Memory Consolidation
2009
The network of protein–protein interactions within the human U4/U6.U5 tri-snRNP
2006
Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29
2013 StandoutNobel
RNA helicases at work: binding and rearranging
2010
A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro
1999
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
Protein Composition and Electron Microscopy Structure of Affinity-Purified Human Spliceosomal B Complexes Isolated under Physiological Conditions
2006
A Preorganized Active Site in the Crystal Structure of the Tetrahymena Ribozyme
1998 ScienceNobel
Exosomal microRNA-21-5p Mediates Mesenchymal Stem Cell Paracrine Effects on Human Cardiac Tissue Contractility
2018
Spliceosomal Small Nuclear Ribonucleoprotein Particles Repeatedly Cycle through Cajal Bodies
2008
RNA–protein analysis using a conditional CRISPR nuclease
2013 StandoutNobel
Cbf5p, a potential pseudouridine synthase, and Nhp2p, a putative RNA-binding protein, are present together with Gar1p in all H BOX/ACA-motif snoRNPs and constitute a common bipartite structure
1998
In Vivo Imaging of Membrane-Associated Glycans in Developing Zebrafish
2008 StandoutScienceNobel
MECHANISTIC ASPECTS OF ENZYMATIC CATALYSIS: Lessons from Comparison of RNA and Protein Enzymes
1997
Crystal Structure of a Group I Ribozyme Domain: Principles of RNA Packing
1996 StandoutScienceNobel
Spliceosome Activation by PRP2 ATPase prior to the First Transesterification Reaction of Pre-mRNA Splicing
1996
A magnesium ion core at the heart of a ribozyme domain
1997 StandoutNobel
The U1 snRNP Base Pairs with the 5′ Splice Site within a Penta-snRNP Complex
2003
The Human U5-220kD Protein (hPrp8) Forms a Stable RNA-Free Complex with Several U5-Specific Proteins, Including an RNA Unwindase, a Homologue of Ribosomal Elongation Factor EF-2, and a Novel WD-40 Protein
1998
The State of Synapses in Fragile X Syndrome
2009
The ribosomal translocase homologue Snu114p is involved in unwinding U4/U6 RNA during activation of the spliceosome
2002
Genome-wide comprehensive analysis of human helicases
2011
Clustering to identify RNA conformations constrained by secondary structure
2011 StandoutNobel
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Structure of a Multipartite Protein-Protein Interaction Domain in Splicing Factor Prp8 and Its Link to Retinitis Pigmentosa
2007
Splicing in disease: disruption of the splicing code and the decoding machinery
2007
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Purification of the yeast U4/U6⋅U5 small nuclear ribonucleoprotein particle and identification of its proteins
1999
The P4−P6 Domain Directs Higher Order Folding of the Tetrahymena Ribozyme Core
1997 StandoutNobel
Dynamics of Thermal Motions within a Large Catalytic RNA Investigated by Cross-linking with Thiol−Disulfide Interchange
1997 Nobel
Ribozyme Structures and Mechanisms
2000 StandoutNobel
Crystal structure of the ribosomal RNA domain essential for binding elongation factors
1998 StandoutNobel
The small ribosomal subunit from Thermus thermophilus at 4.5 Å resolution: Pattern fittings and the identification of a functional site
1999 StandoutNobel
Allosteric Cascade of Spliceosome Activation
2002
Targeted Deletion of MicroRNA-22 Promotes Stress-Induced Cardiac Dilation and Contractile Dysfunction
2012
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
Rapid metabolic evolution in human prefrontal cortex
2011 StandoutNobel
HIERARCHY AND DYNAMICS OF RNA FOLDING
1997
Energetics and Cooperativity of Tertiary Hydrogen Bonds in RNA Structure
1999 Nobel
The P5abc Peripheral Element Facilitates Preorganization of the Tetrahymena Group I Ribozyme for Catalysis
2000 StandoutNobel
Identification of many microRNAs that copurify with polyribosomes in mammalian neurons
2003 StandoutNobel
A 1.3-Å resolution crystal structure of the HIV-1 trans-activation response region RNA stem reveals a metal ion-dependent bulge conformation
1998 StandoutNobel
Genome-wide comprehensive analysis of human helicases.
2011
Kinetic Intermediates Trapped by Native Interactions in RNA Folding
1998 Science
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Effects of the U1C L13 mutation and temperature regulation of yeast commitment complex formation
2004 StandoutNobel
Proteomics Analysis Reveals Stable Multiprotein Complexes in Both Fission and Budding Yeasts Containing Myb-Related Cdc5p/Cef1p, Novel Pre-mRNA Splicing Factors, and snRNAs
2002
RNA Folding at Millisecond Intervals by Synchrotron Hydroxyl Radical Footprinting
1998 Science
A Detailed View of a Ribosomal Active Site
1999 StandoutNobel
Structural Insights into Group II Intron Catalysis and Branch-Site Selection
2002 StandoutScienceNobel
Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA
2004 StandoutNobel
Mouse neurexin-1α deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments
2009 StandoutNobel
p68 RNA Helicase Is an Essential Human Splicing Factor That Acts at the U1 snRNA-5′ Splice Site Duplex
2002
Works of Bernhard Laggerbauer being referenced
Tdrd3 is a novel stress granule-associated protein interacting with the Fragile-X syndrome protein FMRP
2008
Evidence that fragile X mental retardation protein is a negative regulator of translation
2001
Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling
2017
Viral Vector-Based Targeting of miR-21 in Cardiac Nonmyocyte Cells Reduces Pathologic Remodeling of the Heart
2016
The human U5 snRNP 52K protein (CD2BP2) interacts with U5-102K (hPrp6), a U4/U6.U5 tri-snRNP bridging protein, but dissociates upon tri-snRNP formation
2005
Identification of an RNA-Dependent ATPase Activity in Mammalian U5 snRNPs
1996
IGHMBP2 is a ribosome-associated helicase inactive in the neuromuscular disorder distal SMA type 1 (DSMA1)
2009
An evolutionarily conserved U5 snRNP-specific protein is a GTP-binding factor closely related to the ribosomal translocase EF-2
1997
Spinal muscular atrophy: the RNP connection
2006
Reduced U snRNP assembly causes motor axon degeneration in an animal model for spinal muscular atrophy
2005
A phenotypic screen to identify hypertrophy-modulating microRNAs in primary cardiomyocytes
2011
Two major tertiary folding transitions of the Tetrahymena catalytic RNA.
1994 Nobel
The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplicesin vitro
1998
Crosslinking of the U5 snRNP-specific 116-kDa protein to RNA hairpins that block step 2 of splicing.
1997