Citation Impact
Citing Papers
Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation
2009 StandoutScience
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
2013 StandoutScience
Fragile X Mental Retardation Protein Targets G Quartet mRNAs Important for Neuronal Function
2001
β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin
2001 Standout
Basal cell carcinoma possibly originates from the outer root sheath and/or the bulge region of the vellus hair follicle
1999
The epidermis: rising to the surface
1994
A reversible wet/dry adhesive inspired by mussels and geckos
2007 StandoutNature
Cell mechanics and the cytoskeleton
2010 StandoutNature
Cutaneous Wound Healing
1999 Standout
Control of somatic tissue differentiation by the long non-coding RNA TINCR
2012 StandoutNature
Atopic Dermatitis
2008 Standout
Perfect wound healing in the keratin 8 deficient mouse embryo
1996
Epidermal detachment, desmosomal dissociation, and destabilization of corneodesmosin in Spink5-/- mice
2004
Decreased Deiminated Keratin K1 in Psoriatic Hyperproliferative Epidermis
2000
Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis
1990 Standout
Intermediate filaments: primary determinants of cell architecture and plasticity
2009
Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome
2003 StandoutNature
Rheumatoid arthritis
2016 Standout
The immunogenetics of asthma and eczema: a new focus on the epithelium
2004
Nuclear RNA export
1998 StandoutNobel
A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition
1998 StandoutNobel
A missense mutation in type VII collagen in two affected siblings with recessive dystrophic epidermolysis bullosa
1993
Pathogenesis and clinical features of psoriasis
2007 Standout
Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi
2001 StandoutNature
Meta-analysis of cancer gene expression signatures reveals new cancer genes, SAGE tags and tumor associated regions of co-regulation
2010
A Putative Mammalian RNA Helicase with an Arginine-Serine-rich Domain Colocalizes with a Splicing Factor
1995 StandoutNobel
Linkers in the structural biology of protein–protein interactions
2012
The genetics of psoriasis, psoriatic arthritis and atopic dermatitis
2004
MUT-16 promotes formation of perinuclear Mutator foci required for RNA silencing in the C. elegans germline
2012 StandoutNobel
Pathogenesis and therapy of psoriasis
2007 StandoutNature
Atopic dermatitis
2015 Standout
Pfam: the protein families database
2013 Standout
Cryo‐electron microscopy of vitreous sections
2004 StandoutNobel
A Mutation in the V1 End Domain of Keratin 1 in Non-Epidermolytic Palmar-Plantar Keratoderma
1994
Molecular Cloning of the Gene for the Human Prostaglandin Transporter hPGT: Gene Organization, Promoter Activity, and Chromosomal Localization
1998
The Atopic March: Progression from Atopic Dermatitis to Allergic Rhinitis and Asthma
2014
Esophageal Cancer
2003 Standout
Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors
1993
Fine Mapping of the PSORS4 Psoriasis Susceptibility Region on Chromosome 1q21
2001
The Hedgehog and Wnt signalling pathways in cancer
2001 StandoutNature
Keratin 14 Gene Mutations in Patients with Epidermolysis Bullosa Simplex
1995
Sequence and Expression Patterns of Mouse SPR1: Correlation of Expression with Epithelial Function
1996
Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease
2000
Mutations in the hair cortex keratin hHb6 cause the inherited hair disease monilethrix
1997
Using the Acropora digitifera genome to understand coral responses to environmental change
2011 StandoutNature
Paternal Uniparental Disomy for Chromosome 1 Revealed by Molecular Analysis of a Patient with Pycnodysostosis
1998
FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
2011 Standout
Loricrin Expression Is Coordinated with Other Epidermal Proteins and the Appearance of Lipid Lamellar Granules in Development
1995
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Cutaneous cysts of Gardner's syndrome are similar to follicular stem cells
1995
Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations
2006
S100A11, S100A10, Annexin I, Desmosomal Proteins, Small Proline-rich Proteins, Plasminogen Activator Inhibitor-2, and Involucrin Are Components of the Cornified Envelope of Cultured Human Epidermal Keratinocytes
1997
Tissue Kallikrein Inhibitors Based on the Sunflower Trypsin Inhibitor Scaffold – A Potential Therapeutic Intervention for Skin Diseases
2016 StandoutNobel
The cornified envelope: a model of cell death in the skin
2005 Standout
The development of allergic inflammation
2008 StandoutNature
A molecular defect in loricrin, the major component of the cornified cell envelope, underlies Vohwinkel's syndrome
1996
Tylosis associated with carcinoma of the oesophagus and oral leukoplakia in a large Liverpool family—A review of six generations
1994
Skin barrier function, epidermal proliferation and differentiation in eczema
2006
Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis
1996 Standout
Psoriasis genetics: breaking the barrier
2010
Quasi-Normal Cornified Cell Envelopes in Loricrin Knockout Mice Imply the Existence of a Loricrin Backup System
2002
The Catalog of Human Hair Keratins
1999
Expression Cloning of Human Corneodesmosin Proves Its Identity with the Product of the S Gene and Allows Improved Characterization of Its Processing during Keratinocyte Differentiation
1998
Intermediate Filament Proteins and Their Associated Diseases
2004
The genetics of atopic dermatitis: recent findings and future options
2005
Intermediate filaments: molecular architecture, assembly, dynamics and polymorphism
1999
Keratin 13 point mutation underlies the hereditary mucosal epithelia disorder white sponge nevus
1995
Possible new therapeutic strategy to regulate atopic dermatitis through upregulating filaggrin expression
2013
Decreased expression of filaggrin in atopic skin
1996
The Proteins Elafin, Filaggrin, Keratin Intermediate Filaments, Loricrin, and Small Proline-rich Proteins 1 and 2 Are Isodipeptide Cross-linked Components of the Human Epidermal Cornified Cell Envelope
1995
p63 is a p53 homologue required for limb and epidermal morphogenesis
1999 StandoutNature
Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march
2006
Intermediate filaments in disease
1995
Organization and Expression of Hair Follicle Genes.
1993
Hoxc13 mutant mice lack external hair
1998 StandoutNobel
De Novo Hair Follicle Morphogenesis and Hair Tumors in Mice Expressing a Truncated β-Catenin in Skin
1998 Standout
Characterization of the human S100A12 (calgranulin C, p6, CAAF1, CGRP) gene, a new member of the 5100 gene cluster on chromosome 1q21
1996
Phenotypes, genotypes and their contribution to understanding keratin function
2003
Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris
2006
Identification of citrulline residues in the V subdomains of keratin K1 derived from the cornified layer of newborn mouse epidermis
1999
MEP-1 and a Homolog of the NURD Complex Component Mi-2 Act Together to Maintain Germline-Soma Distinctions in C. elegans
2002 StandoutNobel
Obstructive sleep apnoea and its cardiovascular consequences
2008 Standout
Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model
2004
Intermediate filament structure
1992
Adhesive force of a single gecko foot-hair
2000 StandoutNature
A recurrent mutation in the loricrin gene underlies the ichthyotic variant of Vohwinkel syndrome
2002
Unique mutations in the filaggrin gene in Japanese patients with ichthyosis vulgaris and atopic dermatitis
2007
The role of keratin proteins and their genes in the growth, structure and properties of hair
1997
Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
2006 StandoutNature
Refined Characterization of Corneodesmosin Proteolysis during Terminal Differentiation of Human Epidermis and Its Relationship to Desquamation
2001
A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle
1998
Direct Evidence That Involucrin Is a Major Early Isopeptide Cross-linked Component of the Keratinocyte Cornified Cell Envelope
1997
RAGE Mediates a Novel Proinflammatory Axis
1999 Standout
Activated keratinocytes in the epidermis of hypertrophic scars.
1998
A functional "knockout" of human keratin 14.
1994
Kinetics of 5α-Cholestan-3β-ylN-(2-Naphthyl)carbamate/n-Alkane Organogel Formation and Its Influence on the Fibrillar Networks
2005
Skeletal matrix proteins of invertebrate animals: Comparative analysis of their amino acid sequences
2006
Lessons from Loricrin-Deficient Mice
2000
Developmental Expression of a Tandemly Repeated, Glycine- and Serine-Rich Spore Wall Protein in the Microsporidian Pathogen Encephalitozoon cuniculi
2000
Combinatorial RNA interference indicates GLH-4 can compensate for GLH-1; these two P granule components are critical for fertility in C. elegans
2000
The molecular basis for inherited bullous diseases
1996
A human keratin 14 "knockout": the absence of K14 leads to severe epidermolysis bullosa simplex and a function for an intermediate filament protein.
1994
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
2015 StandoutNobel
Whisker growth after removal of the dermal papilla and lengths of follicle in the hooded rat
1966
S100 Protein Subcellular Localization During Epidermal Differentiation and Psoriasis
2003
Organogel Formation by a Cholesterol-Stoppered Bistable [2]Rotaxane and Its Dumbbell Precursor
2008 StandoutNobel
Multiple potential germ-line helicases are components of the germ-line-specific P granules of Caenorhabditis elegans
1996
The extracellular matrix geneFrem1is essential for the normal adhesion of the embryonic epidermis
2004 StandoutNobel
Inhibition of Serine Proteinases Plasmin, Trypsin, Subtilisin A, Cathepsin G, and Elastase by LEKTI: A Kinetic Analysis
2003
Wound Healing--Aiming for Perfect Skin Regeneration
1997 StandoutScience
Structure, Function, and Dynamics of Keratin Intermediate Filaments
1993
Biochemical, Structural, and Transglutaminase Substrate Properties Of Human Loricrin, the Major Epidermal Cornified Cell Envelope Protein
1995
Identification and Characterization of a Yeast Gene Encoding the U2 Small Nuclear Ribonucleoprotein Particle B″ Protein
1996 StandoutNobel
Functional π-Gelators and Their Applications
2014 Standout
Dynamics of keratin assembly: exogenous type I keratin rapidly associates with type II keratin in vivo
1993
The structure of the digital setae of lizards
1965
Functional diversity of the hnRNPs: past, present and perspectives
2010
Nuclear Import and the Evolution of a Multifunctional RNA-binding Protein
1998 StandoutNobel
A highly conserved lysine residue on the head domain of type II keratins is essential for the attachment of keratin intermediate filaments to the cornified cell envelope through isopeptide crosslinking by transglutaminases
1998
Transgenic Mice Expressing a Mutant Form of Loricrin Reveal the Molecular Basis of the Skin Diseases, Vohwinkel Syndrome and Progressive Symmetric Erythrokeratoderma
2000
The genetics of psoriasis.
1994
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
Cathepsin D is involved in the regulation of transglutaminase 1 and epidermal differentiation
2004
Human Homolog of patched , a Candidate Gene for the Basal Cell Nevus Syndrome
1996 StandoutScience
The Caenorhabditis elegans gene mek-2 is required for vulval induction and encodes a protein similar to the protein kinase MEK.
1995 StandoutNobel
A Distinct and Parallel Pathway for the Nuclear Import of an mRNA-binding Protein
1997 StandoutNobel
Conserved Structures and Diversity of Functions of RNA-Binding Proteins
1994 StandoutScience
Overexpression of human loricrin in transgenic mice produces a normal phenotype.
1993
Effective amplification of long targets from cloned inserts and human genomic DNA.
1994
The human loricrin gene.
1992
Works of Bernhard Korge being referenced
Solid basal cell epithelioma (BCE) possibly originates from the outer root sheath of the hair follicle.
1993
Linkage of epidermolytic hyperkeratosis to the type II keratin gene cluster on chromosome 12q
1992
Genetic Analysis of the Epidermal Differentiation Complex (EDC) on Human Chromosome 1q21: Chromosomal Orientation, New Markers, and a 6-Mb YAC Contig
1996
Physical Mapping of a Functional Cluster of Epidermal Differentiation Genes on Chromosome 1q21
1993
Keratin and keratinization
1994
Sequence Data and Chromosomal Localization of Human Type I and Type II Hair Keratin Genes
1995
Normal psoriatic epidermis expression of hyperproliferation-associated keratins
1991
Genetic analysis of a severe case of Netherton syndrome and application for prenatal testing
2002
Glycine loops in proteins: their occurence in certain intermediate filament chains, loricrins and single-stranded RNA binding proteins
1991
Hailey-Hailey Disease Maps to a 5 cM Interval on Chromosome 3q21-q24
1995
Novel and recurrent mutations in keratinKRT5andKRT14genes in epidermolysis bullosa simplex: implications for disease phenotype and keratin filament assembly
2006
Genes Encoding Structural Proteins of Epidermal Cornification and S100 Calcium-Binding Proteins Form a Gene Complex (“Epidermal Differentiation Complex”) on Human Chromosome 1q21
1996
A leucine→proline mutation in the H1 subdomain of keratin 1 causes epidermolytic hyperkeratosis
1992
A Mutational Hotspot in the 2B Domain of Human Hair Basic Keratin 6 (hHb6) in Monilethrix Patients
1998
Fine Mapping of the Darier's Disease Locus on Chromosome 12q
1994
The Two Size Alleles of Human Keratin 1 Are Due to a Deletion in the Glycine-Rich Carboxyl-Terminal V2 Subdomain
1992
Loricrin Mutation in Vohwinkel’s Keratoderma Is Unique to the Variant with Ichthyosis
1997
Novel K5 and K14 Mutations in German Patients with the Weber–Cockayne Variant of Epidermolysis Bullosa Simplex
1998
A cDNA encoding the human type I hair keratin hHa1
1995
Extensive size polymorphism of the human keratin 10 chain resides in the C-terminal V2 subdomain due to variable numbers and sizes of glycine loops.
1992
The Cornified Cell Envelope: Loricrin and Transglutaminases
1992
Effects of 13-Cis-Retinoic Acid, All-Trans-Retinoic Acid, and Acitretin on the Proliferation, Lipid Synthesis and Keratin Expression of Cultured Human Sebocytes In Vitro
1991