Standout Papers
Citation Impact
Citing Papers
Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 StandoutScienceNobel
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
A type I interferon autocrine–paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells
2005
The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency
2008 StandoutScienceNobel
TNF Receptor-Deficient Mice Reveal Divergent Roles for p55 and p75 in Several Models of Inflammation
1998
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
1996 Nature
Structure and Function of Leukocyte Integrins
1990
Tumor-targeting peptides from combinatorial libraries
2016
Analysis of Expression of Lymphocyte Homing-Related Adhesion Molecules in ALY Mice Deficient in Lymph Nodes and Peyer's Patches
1997
Inflammation and cancer
2002 StandoutNature
Selective modulation of the expression of L-selectin ligands by an immune response
1995
T Cell and Cytokine Regulation of the IgA Response
1998
Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity
1991 Standout
An endogenous retrovirus mediating deletion of αβ T cells?
1991 Nature
An essential function for the nuclear receptor RORγt in the generation of fetal lymphoid tissue inducer cells
2003
Death by TNF: a road to inflammation
2022
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
Physiological and Molecular Mechanisms of Lymphocyte Homing
1992
Decreased response to recall antigens is associated with depressed costimulatory receptor expression in septic critically ill patients
2000
The generation of diversity and pattern in animal development
1992 StandoutNobel
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Topologically Chiral Covalent Assemblies of Molecular Knots with Linear, Branched, and Cyclic Architectures
2004
Cytokine regulation of secondary lymphoid organ development
1998
Monoclonal antibodies to the integrin α−4 subunit inhibit the murine contact hypersensitivity response
1993
Synaptic transmission: A bidirectional and self-modifiable form of cell-cell communication
1993 StandoutNobel
The Hallmarks of Cancer
2000 Standout
Courtship in S. cerevisiae: Both cell types choose mating partners by responding to the strongest pheromone signal
1990 StandoutNobel
The Oncogenic Cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development
1994 StandoutNobel
Endothelial-Leukocyte Adhesion Molecules
1993
Critical role for β7 integrins in formation of the gut-associated lymphoid tissue
1996 Nature
Immunodesign of experimental sepsis by cecal ligation and puncture
2008 Standout
Telomere Length and Telomerase Expression in Atypical Adenomatous Hyperplasia and Small Bronchioloalveolar Carcinoma of the Lung
2007
A role for the Drosophila neurogenic genes in mesoderm differentiation
1991 StandoutNobel
Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant
1994 Nature
Extracellular Matrix Molecules and their Receptors: Functions in Neural Development
1991
Lymphocyte interactions with endothelial cells
1992
Increased telomerase activity and comprehensive lifestyle changes: a pilot study
2008 StandoutNobel
Signal characteristics of G protein-transactivated EGF receptor
1997
Perspectives series: cell adhesion in vascular biology. Integrin signaling in vascular biology.
1997
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
1994 StandoutNobel
The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games
2005
Cell adhesion molecules of the immunoglobulin supergene family and their role in malignant transformation and progression to metastatic disease
1991
MAdCAM-1 has homology to immunoglobulin and mucin-like adhesion receptors and to IgA1
1993 Nature
Organogenesis of lymphoid tissues
2003
VLA Proteins in the Integrin Family: Structures, Functions, and Their Role on Leukocytes
1990
The resistance againstListeria monocytogenes and the formation of germinal centers depend on a functional death domain of the 55 kDa tumor necrosis factor receptor
1999
Homing receptors reexamined: mouse LECAM‐1 (MEL‐14 antigen) is involved in lymphocyte migration into gut‐associated lymphoid tissue
1991
Adhesion receptors of the immune system
1990 StandoutNature
Taking dendritic cells into medicine
2007 StandoutNatureNobel
L-selectin-mediated lymphocyte rolling on MAdCAM-1
1993 Nature
A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells
1990
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
In situ class switching and differentiation to IgA-producing cells in the gut lamina propria
2001 StandoutNatureNobel
EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor
1994
Fibulin-5/DANCE is essential for elastogenesis in vivo
2002 StandoutNatureNobel
Atherosclerosis — An Inflammatory Disease
1999 Standout
Novel tumor necrosis factor‐knockout mice that lack Peyer's patches
2005
Tissue‐specific migration pathways by phenotypically distinct subpopulations of memory T cells
1992
Intestinal IgA Synthesis: A Primitive Form of Adaptive Immunity That Regulates Microbial Communities in the Gut
2006
Membrane Proteins Involved in Phagocyte Adherence to Endothelium
1990
Homing receptors and addressins
1991
The Pathophysiology and Treatment of Sepsis
2003 Standout
Intestinal IgA synthesis: regulation of front-line body defences
2003 StandoutNobel
Knotting and Threading of Molecules: Chemistry and Chirality of Molecular Knots and Their Assemblies
2005
Involvement of growth factor receptors in the mammalian UVC response
1994
The origin and function of tumor-associated macrophages
1992
Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
1994 Standout
Functional Porous Coordination Polymers
2004 StandoutNobel
Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons
1992
Genes encoding ligands for deletion of Vβ11 T cells cosegregate with mammary tumour virus genomes
1991 Nature
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Cancer-related inflammation
2008 StandoutNature
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice
1994
A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice
1994
Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
2008 Standout
The role of lymphotoxin in development and maintenance of secondary lymphoid tissues
2003
VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site
1990 Standout
Distinct roles for lymphotoxin‐α and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissue
1997
Virus-specific CD8+ T-cell memory determined by clonal burst size
1994 StandoutNatureNobel
Normal Responses to Injury Prevent Systemic Inflammation and Can Be Immunosuppressive
2001
Immunological Memory
1993
The influence of afferent lymphatic vessel interruption on vascular addressin expression.
1991
Chemical Topology: Complex Molecular Knots, Links, and Entanglements
2011 StandoutNobel
Generation of Lymphohematopoietic Cells from Embryonic Stem Cells in Culture
1994 StandoutScienceNobel
Peyer’s patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor
1997
Localization of ligands for L-selectin in mouse peripheral lymph node high endothelial cells by colloidal gold conjugates
1994
Intraepithelial lymphocytes. Anatomical site, not T cell receptor form, dictates phenotype and function.
1989
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
The integrin alpha 9 beta 1 mediates cell attachment to a non-RGD site in the third fibronectin type III repeat of tenascin.
1994
The Role of Thymus-Expressed Chemokine and Its Receptor CCR9 on Lymphocytes in the Regional Specialization of the Mucosal Immune System
2000
The human peripheral lymph node vascular addressin is a ligand for LECAM-1, the peripheral lymph node homing receptor.
1991
Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
2005 StandoutNobel
A family of beta 7 integrins on human mucosal lymphocytes.
1992
Characterization of tumor necrosis factor-deficient mice
1997
Activation and inhibition of erythropoietin receptor function: role of receptor dimerization.
1994
PECAM-1 is required for transendothelial migration of leukocytes.
1993
Essential roles of tumor necrosis factor receptor p55 in liver metastasis of intrasplenic administration of colon 26 cells.
2002
A 20-Å-Thick Interwoven Sheet Consisting of Nanotubes
2002
Distinct Roles of Lymphotoxin α and the Type I Tumor Necrosis Factor (TNF) Receptor in the Establishment of Follicular Dendritic Cells from Non–Bone Marrow–derived Cells
1997
Dual inhibition of VLA-4 and LFA-1 maximally inhibits cutaneous delayed-type hypersensitivity-induced inflammation.
1993
Expression of the integrin αEβ7identifies unique subsets of CD25+as well as CD25−regulatory T cells
2002
Adhesion to vascular cell adhesion molecule 1 and fibronectin. Comparison of alpha 4 beta 1 (VLA-4) and alpha 4 beta 7 on the human B cell line JY.
1992
Stable expression of truncated inositol 1,4,5-trisphosphate receptor subunits in 3T3 fibroblasts. Coordinate signaling changes and differential suppression of cell growth and transformation.
1994 StandoutNobel
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation
2007
Subtle Role of Polyatomic Anions in Molecular Construction: Structures and Properties of AgX Bearing 2,4‘-Thiobis(pyridine) (X- = NO3-, BF4-, ClO4-, PF6-, CF3CO2-, and CF3SO3-)
2003
Toll-like receptors in the pathogenesis of human disease
2004
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations
2000 StandoutScienceNobel
Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein.
1996 StandoutNobel
Inflammatory Cells and Cancer
2001
Sulfation-dependent recognition of high endothelial venules (HEV)-ligands by L-selectin and MECA 79, and adhesion-blocking monoclonal antibody.
1994
Normal Development of Mice Deficient in β 2 M, MCClass I Proteins, and CD8 + T Cells
1990 StandoutScienceNobel
Epithelial M Cells: Differentiation and Function
2000
Investigation of the mechanism of the dominant negative effect of mutations in the tyrosine kinase domain of the insulin receptor.
1994
Maintenance of in Vivo Tolerance by Persistence of Antigen
1992 StandoutScienceNobel
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response.
1996
DEVELOPMENT AND MATURATION OF SECONDARY LYMPHOID TISSUES
1999
Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: possible involvement of TNFalpha and IL-1alpha.
2000
Conformational Strain of Macrocyclic Peptides in Ligand–Receptor Complexes Based on Advanced Refinement of Bound-State Conformers
2021
Mouse Lymph Node Homing Receptor cDNA Clone Encodes a Glycoprotein Revealing Tandem Interaction Domains
1989 Science
Critical Role of T Cell-Dependent Serum Antibody, but Not the Gut-Associated Lymphoid Tissue, for Surviving Acute Mucosal Infection with Citrobacter rodentium, an Attaching and Effacing Pathogen
2004
Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering
1992
CD34-deficient mice have reduced eosinophil accumulation after allergen exposure and show a novel crossreactive 90-kD protein
1996 StandoutNobel
Triggering of the CD44 antigen on T lymphocytes promotes T cell adhesion through the LFA-1 pathway.
1990
PanR1, a Dominant Negative Missense Allele of the Gene Encoding TNF-α (Tnf), Does Not Impair Lymphoid Development
2006 StandoutNobel
Unraveling Function in the TNF Ligand and Receptor Families
1994 StandoutScienceNobel
L-selectin can facilitate metastasis to lymph nodes in a transgenic mouse model of carcinogenesis
2001
YERSINIA OUTER PROTEINS: Role in Modulation of Host Cell Signaling Responses and Pathogenesis
2005
Works of Bernhard Holzmann being referenced
Selective defects of T lymphocyte function in patients with lethal intraabdominal infection
1999
Animal Models of sepsis: setting the stage
2005
Sepsis after major visceral surgery is associated with sustained and interferon-γ–resistant defects of monocyte cytokine production
2000
Effects of functional Toll‐like receptor‐4 mutations on the immune response to human and experimental sepsis
2003
A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain
2019
Identification of a TLR4‐ and TRIF‐dependent activation program of dendritic cells
2004 StandoutNobel
Inflammatory cell infiltrates in human melanoma at different stages of tumor progression
1988
Developmental Analysis of the Mouse Hematolymphoid System
1989
Combinatorial and Rational Strategies To Develop Nonpeptidic α4β7-Integrin Antagonists from Cyclic Peptides
2002
Design, Synthesis, and Biological Evaluation ofα4β1 Integrin Antagonists Based onβ-D-Mannose as Rigid Scaffold
2001
Lymphocyte Homing Receptors
1992
α4 Integrins and Tumor Metastasis
1998
The Melanoma Progression-Associated Antigen P3.58 is Identical to the Intercellular Adhesion Molecule, ICAM-1
1988
α4β7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1
1993
Integrin Molecules Involved in Lymphocyte Homing to Peyer's Patches
1989
Identification of a murine Peyer's patch—specific lymphocyte homing receptor as an integrin molecule with an α chain homologous to human VLA-4α
1989
Anti-Oncogenic Activity of Signalling-Defective Epidermal Growth Factor Receptor Mutants
1992
Telomere Length and Human Telomerase Reverse Transcriptase Expression As Markers for Progression and Prognosis of Colorectal Carcinoma
2004
Inhibition of Interleukin-22 Attenuates Bacterial Load and Organ Failure during Acute Polymicrobial Sepsis
2007
In situ analysis of antigens on malignant and benign cells of the melanocyte lineage. Differential expression of two surface molecules, gp75 and p89.
1985
Expression of the mucosal vascular addressin, MAdCAM-1, on sinus-lining cells in the spleen.
1995
Characterization of a rat monoclonal antibody specific for a determinant encoded by the V beta 7 gene segment. Depletion of V beta 7+ T cells in mice with Mls-1a haplotype.
1990
Signaling of Apoptosis through TLRs Critically Involves Toll/IL-1 Receptor Domain-Containing Adapter Inducing IFN-β, but Not MyD88, in Bacteria-Infected Murine Macrophages
2004
Peyer's patch-specific lymphocyte homing receptors consist of a VLA-4-like alpha chain associated with either of two integrin beta chains, one of which is novel.
1989
Discrimination between benign and malignant cells of melanocytic lineage by two novel antigens, a glycoprotein with a molecular weight of 113,000 and a protein with a molecular weight of 76,000.
1987
Cloning and expression of mouse integrin beta p(beta 7): a functional role in Peyer's patch-specific lymphocyte homing.
1992
Crucial role of 55-kilodalton TNF receptor in TNF-induced adhesion molecule expression and leukocyte organ infiltration
1996
Distinct mechanisms of immunosuppression as a consequence of major surgery
1997
Distinct but overlapping epitopes are involved in alpha 4 beta 7-mediated adhesion to vascular cell adhesion molecule-1, mucosal addressin-1, fibronectin, and lymphocyte aggregation.
1994
Defective Peyer's patch organogenesis in mice lacking the 55-kD receptor for tumor necrosis factor.
1996
Anti-oncogenic activity of signalling-defective epidermal growth factor receptor mutants.
1992
Combinatorial and Rational Strategies To Develop Nonpeptidic α4β7-Integrin Antagonists from Cyclic Peptides
2002
Increased Susceptibility to Postoperative Sepsis in Patients with Impaired Monocyte IL-12 Production
1998
Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo.
1994
Cloning and expression of cDNAs for the alpha subunit of the murine lymphocyte-Peyer's patch adhesion molecule.
1991
Tumor progression in human malignant melanoma: Five stages defined by their antigenic phenotypes
1987
Essential Role of Gamma Interferon in Survival of Colon Ascendens Stent Peritonitis, a Novel Murine Model of Abdominal Sepsis
1998