Standout Papers
Citation Impact
Citing Papers
Computer‐Assisted Synthetic Planning: The End of the Beginning
2016
Direct and Catalytic C ‐Glycosylation of Arenes: Expeditious Synthesis of the Remdesivir Nucleoside**
2021 StandoutNobel
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
Sequence-regulated copolymerization based on periodic covalent positioning of monomers along one-dimensional nanochannels
2018 StandoutNobel
Microwave chemistry for inorganic nanomaterials synthesis
2010 Standout
Flow Metal‐Free ArC Bond Formation via Photogenerated Phenyl Cations
2016
Microwave‐Assisted Synthesis of Colloidal Inorganic Nanocrystals
2011
Extremely Fast Gas/Liquid Reactions in Flow Microreactors: Carboxylation of Short‐Lived Organolithiums
2014
Recent advances in [2+2+2] cycloaddition reactions
2011 Standout
Continuous In Situ Generation, Separation, and Reaction of Diazomethane in a Dual‐Channel Microreactor
2011
Sulfoximines from a Medicinal Chemist's Perspective: Physicochemical and in vitro Parameters Relevant for Drug Discovery
2016
Selection of boron reagents for Suzuki–Miyaura coupling
2013 Standout
Automating drug discovery
2017
Continuous in situ generation and reaction of phosgene in a microflow system
2011
Odorless Isocyanide Chemistry: An Integrated Microfluidic System for a Multistep Reaction Sequence
2013
Machine learning for molecular and materials science
2018 StandoutNature
An autonomous organic reaction search engine for chemical reactivity
2017
Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion
2008 StandoutNature
The synthesis of active pharmaceutical ingredients (APIs) using continuous flow chemistry
2015
High-performance medicine: the convergence of human and artificial intelligence
2018 Standout
Rapid and Efficient Copper‐Catalyzed Finkelstein Reaction of (Hetero)Aromatics under Continuous‐Flow Conditions
2014
Microwave Effects in Organic Synthesis: Myth or Reality?
2012
Flow carbonylation of sterically hindered ortho-substituted iodoarenes
2016
Multistage extraction platform for highly efficient and fully continuous purification of nanoparticles
2017 StandoutNobel
In Situ Generation of Diimide from Hydrazine and Oxygen: Continuous‐Flow Transfer Hydrogenation of Olefins
2013
Artificial intelligence in drug development: present status and future prospects
2018 Standout
Direct Arylation of Benzene with Aryl Bromides using High‐Temperature/High‐Pressure Process Windows: Expanding the Scope of CH Activation Chemistry
2012
The past, present and potential for microfluidic reactor technology in chemical synthesis
2013
In Situ Generated Iron Oxide Nanocrystals as Efficient and Selective Catalysts for the Reduction of Nitroarenes using a Continuous Flow Method
2012
Syntheses of 2-substituted 1-amino-4-bromoanthraquinones (bromaminic acid analogues) – precursors for dyes and drugs
2015
The Microwave‐to‐Flow Paradigm: Translating High‐Temperature Batch Microwave Chemistry to Scalable Continuous‐Flow Processes
2011
Asymmetric Organocatalysis and Analysis on a Single Microfluidic Nanospray Chip
2011
Continuous-flow catalytic asymmetric hydrogenations: Reaction optimization using FTIR inline analysis
2012
Immobilized Iron Oxide Nanoparticles as Stable and Reusable Catalysts for Hydrazine‐Mediated Nitro Reductions in Continuous Flow
2014
Beyond Directing Groups: Transition‐Metal‐Catalyzed CH Activation of Simple Arenes
2012 Standout
Diazo Compounds in Continuous‐Flow Technology
2014
Applications of Continuous-Flow Photochemistry in Organic Synthesis, Material Science, and Water Treatment
2016
Iron Catalysis in Organic Synthesis
2015 Standout
Hydrazine-mediated Reduction of Nitro and Azide Functionalities Catalyzed by Highly Active and Reusable Magnetic Iron Oxide Nanocrystals
2013
Microwave food processing—A review
2013 Standout
3d Transition Metals for C–H Activation
2018 Standout
The Golden Age of Transfer Hydrogenation
2015 Standout
Continuous‐Flow Synthesis of Biaryls by Negishi Cross‐Coupling of Fluoro‐ and Trifluoromethyl‐Substituted (Hetero)arenes
2016
Online quantitative mass spectrometry for the rapid adaptive optimisation of automated flow reactors
2015
Contribution of Organofluorine Compounds to Pharmaceuticals
2020 Standout
Cu and Cu-Based Nanoparticles: Synthesis and Applications in Catalysis
2016 Standout
Heterogeneously Catalyzed Alcohol Oxidation for the Fine Chemical Industry
2015
A miniature CSTR cascade for continuous flow of reactions containing solids
2016
A high-temperature continuous stirred-tank reactor cascade for the multistep synthesis of InP/ZnS quantum dots
2021 StandoutNobel
Intensifying Multiphase Reactions and Reactors: Strategies and Examples
2017
Stereo‐ and Chemoselective Character of Supported CeO2 Catalysts for Continuous‐Flow Three‐Phase Alkyne Hydrogenation
2014
Flow Update for a Cossy Photocyclization
2016
Electrospinning and Electrospun Nanofibers: Methods, Materials, and Applications
2019 Standout
Flash carboxylation: fast lithiation–carboxylation sequence at room temperature in continuous flow
2014
Continuous Flow Oxidation of Alcohols and Aldehydes Utilizing Bleach and Catalytic Tetrabutylammonium Bromide
2011
Selective Olefin Reduction in Thebaine Using Hydrazine Hydrate and O2 under Intensified Continuous Flow Conditions
2015
Flow chemistry as a versatile tool for the synthesis of triazoles
2015
2- and 3-Stage temperature ramping for the direct synthesis of adipic acid in micro-flow packed-bed reactors
2014
Organic Photoredox Catalysis
2016 Standout
Iron(II)‐Catalyzed Direct Synthesis of NH Sulfoximines from Sulfoxides
2017
Use of a “Catalytic” Cosolvent, N,N‐Dimethyl Octanamide, Allows the Flow Synthesis of Imatinib with no Solvent Switch
2016
The accelerated preparation of 1,4-dihydropyridines using microflow reactors
2014
The Use of Molecular Oxygen in Pharmaceutical Manufacturing: Is Flow the Way to Go?
2016
Exploring the reactivity of a ruthenium complex in the metathesis of biorenewable feedstocks to generate value-added chemicals
2015
High-performance miniature CSTR for biphasic C–C bond-forming reactions
2017
Electrochemical capacitors: mechanism, materials, systems, characterization and applications
2016 Standout
Chemicals from lignin: an interplay of lignocellulose fractionation, depolymerisation, and upgrading
2018 Standout
Controlled generation and use of CO in flow
2016
Flow chemistry as a discovery tool to access sp2–sp3cross-coupling reactions via diazo compounds
2014
State of the Art and Prospects in Metal–Organic Framework (MOF)-Based and MOF-Derived Nanocatalysis
2019 Standout
Modern Organic Synthesis with α-Diazocarbonyl Compounds
2015
Expanding Access to Remdesivir via an Improved Pyrrolotriazine Synthesis: Supply Centered Synthesis
2020
Microwave material processing—a review
2011
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
A greener process for flow C–H chlorination of cyclic alkanes using in situ generation and on-site consumption of chlorine gas
2016
Catalytic iron-carbene intermediate revealed in a cytochrome c carbene transferase
2018 StandoutNobel
SuFEx Chemistry of Thionyl Tetrafluoride (SOF4) with Organolithium Nucleophiles: Synthesis of Sulfonimidoyl Fluorides, Sulfoximines, Sulfonimidamides, and Sulfonimidates
2018 StandoutNobel
Oxidations of Allylic and Benzylic Alcohols under Inductively‐Heated Flow Conditions with Gold‐Doped Superparamagnetic Nanostructured Particles as Catalyst and Oxygen as Oxidant
2014
Flow Chemistry: Intelligent Processing of Gas–Liquid Transformations Using a Tube-in-Tube Reactor
2015
Multi-step continuous-flow synthesis
2017
Direct Preparation of Nitriles from Carboxylic Acids in Continuous Flow
2013
From alcohol to 1,2,3-triazole via a multi-step continuous-flow synthesis of a rufinamide precursor
2016
Methylation using dimethylcarbonate catalysed by ionic liquids under continuous flow conditions
2012
Rapid Asymmetric Synthesis of Disubstituted Allenes by Coupling of Flow‐Generated Diazo Compounds and Propargylated Amines
2017
Advanced Thermoelectric Design: From Materials and Structures to Devices
2020 Standout
An Investigation of Wall Effects in Microwave-Assisted Ring-Closing Metathesis and Cyclotrimerization Reactions
2010
A Continuous-Flow Microwave Reactor for Conducting High-Temperature and High-Pressure Chemical Reactions
2013
Continuous, Fast, and Safe Aerobic Oxidation of 2-Ethylhexanal: Pushing the Limits of the Simple Tube Reactor for a Gas/Liquid Reaction
2015
Microwave-assisted amination from fluorobenzenes without catalyst and strong base
2012
Development of a Large-Scale Cyanation Process Using Continuous Flow Chemistry En Route to the Synthesis of Remdesivir
2020
On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system
2016 Science
Catalytic Transformation of Lignin for the Production of Chemicals and Fuels
2015 Standout
The utilization of copper flow reactors in organic synthesis
2014
A Sequential Ugi Multicomponent/Cu-Catalyzed Azide–Alkyne Cycloaddition Approach for the Continuous Flow Generation of Cyclic Peptoids
2015
Continuous Flow Nucleophilic Aromatic Substitution with Dimethylamine Generated in Situ by Decomposition of DMF
2013
Sustainable Conversion of Carbon Dioxide: An Integrated Review of Catalysis and Life Cycle Assessment
2017 Standout
Heterogeneous catalysis in continuous flow microreactors: A review of methods and applications
2017
Synthesis of Annulated Pyridines by Intramolecular Inverse‐Electron‐Demand Hetero‐Diels–Alder Reaction under Superheated Continuous Flow Conditions
2011
Microwave-assisted synthesis of metal oxide/hydroxide composite electrodes for high power supercapacitors – A review
2014
Transfer of Electrophilic NH Using Convenient Sources of Ammonia: Direct Synthesis of NH Sulfoximines from Sulfoxides
2016
Mechanistic Insights into Copper(I)‐Catalyzed Azide‐Alkyne Cycloadditions using Continuous Flow Conditions
2010
A scalable and safe continuous flow procedure for in-line generation of diazomethane and its precursor MNU
2016
Multicomponent reactions: advanced tools for sustainable organic synthesis
2014 Standout
Liquid phase oxidation chemistry in continuous-flow microreactors
2015
Continuous Flow Synthesis. A Pharma Perspective
2012
Halogenation of organic compounds using continuous flow and microreactor technology
2016
A Simple Scale-up Strategy for Organolithium Chemistry in Flow Mode: From Feasibility to Kilogram Quantities
2016
Continuous‐Flow Multistep Synthesis of Cinnarizine, Cyclizine, and a Buclizine Derivative from Bulk Alcohols
2015
Development of the Applications of Palladium on Charcoal in Organic Synthesis
2018
Green and Sustainable Solvents in Chemical Processes
2018 Standout
Flow “Fine” Synthesis: High Yielding and Selective Organic Synthesis by Flow Methods
2015
A laboratory-scale continuous flow chlorine generator for organic synthesis
2016
Epoxidation using molecular oxygen in flow: facts and questions on the mechanism of the Mukaiyama epoxidation
2016
Application of Continuous Flow for DIBAL-H Reduction and n-BuLi Mediated Coupling Reaction in the Synthesis of Eribulin Mesylate
2015
Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance
2017 Standout
Flow Chemistry: Recent Developments in the Synthesis of Pharmaceutical Products
2015
Synthetic Methods for Compounds Having CF3–S Units on Carbon by Trifluoromethylation, Trifluoromethylthiolation, Triflylation, and Related Reactions
2014
Fukuyama Reduction and Integrated Thioesterification/Fukuyama Reduction of Thioesters and Acyl Chlorides Using Continuous Flow
2014
Mechanism and Scope of Base‐Controlled Catalyst‐Free N‐Arylation of Amines with Unactivated Fluorobenzenes
2016 StandoutNobel
Optimizing the Heck–Matsuda Reaction in Flow with a Constraint-Adapted Direct Search Algorithm
2016
Synthesis of ketones via organolithium addition to acid chlorides using continuous flow chemistry
2015
Immobilized Transition Metals as Catalysts for Cross‐Couplings in Continuous Flow—A Critical Assessment of the Reaction Mechanism and Metal Leaching
2014
Flow fine synthesis with heterogeneous catalysts
2018
Molecular Docking: Challenges, Advances and its Use in Drug Discovery Perspective
2018 Standout
A Small-Footprint, High-Capacity Flow Reactor for UV Photochemical Synthesis on the Kilogram Scale
2016
An Overview of Coumarin as a Versatile and Readily Accessible Scaffold with Broad-Ranging Biological Activities
2020
Visible-light photoredox catalysis: direct synthesis of fused β-carbolines through an oxidation/[3 + 2] cycloaddition/oxidative aromatization reaction cascade in batch and flow microreactors
2015
Activated carbon supported molybdenum carbides as cheap and highly efficient catalyst in the selective hydrogenation of naphthalene to tetralin
2012
Rapid production of benzazole derivatives by a high-pressure and high-temperature water microflow chemical process
2016
Taming hazardous chemistry by continuous flow technology
2016
Transfer of Electrophilic NH Using Convenient Sources of Ammonia: Direct Synthesis of NH Sulfoximines from Sulfoxides
2016
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Light-Controlled Radical Polymerization: Mechanisms, Methods, and Applications
2016 Standout
Continuous Flow Aerobic Alcohol Oxidation Reactions Using a Heterogeneous Ru(OH)x/Al2O3 Catalyst
2014
Iron-Catalyzed Amination of Sulfides and Sulfoxides with Azides in Photochemical Continuous Flow Synthesis
2016
Flow‐Based, Cerium Oxide Enhanced, Low‐Level Palladium Sonogashira and Heck Coupling Reactions by Perovskite Catalysts
2013
Photoredox Catalysis in Organic Chemistry
2016 Standout
Flow Chemistry on Multigram Scale: Continuous Synthesis of Boronic Acids within 1 s
2016
Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates
2014 Standout
The expanding utility of continuous flow hydrogenation
2015
Continuous flow synthesis of toxic ethyl diazoacetate for utilization in an integrated microfluidic system
2013
Microwave-assisted methylation of phenols with DMF-DMA
2011
Fundamentals and Catalytic Applications of CeO2-Based Materials
2016 Standout
Toward a Continuous‐Flow Synthesis of Boscalid®
2010
A critical assessment of the greenness and energy efficiency of microwave-assisted organic synthesis
2011
Continuous photochemistry: the flow synthesis of ibuprofen via a photo-Favorskii rearrangement
2015
Co/NHPI-mediated aerobic oxygenation of benzylic C–H bonds in pharmaceutically relevant molecules
2016
A General Continuous Flow Method for Palladium Catalysed Carbonylation Reactions Using Single and Multiple Tube‐in‐Tube Gas‐Liquid Microreactors
2014
Synthesis, characterization, and biomedical assessment of novel bisimidazole–coumarin conjugates
2021 Standout
Reaction screening in continuous flow reactors
2016
Dichloromethyllithium: Synthesis and Application in Continuous Flow Mode
2017
Generation and Synthetic Application of Trifluoromethyl Diazomethane Utilizing Continuous Flow Technologies
2016
Solid waste issue: Sources, composition, disposal, recycling, and valorization
2018 Standout
Chemistry Takes a Bath: Reactions in Aqueous Media
2018 StandoutNobel
The merger of transition metal and photocatalysis
2017 Standout
Hydrogen Chloride Gas in Solvent-Free Continuous Conversion of Alcohols to Chlorides in Microflow
2016
Greener and Sustainable Trends in Synthesis of Organics and Nanomaterials
2016
To Be or Not To Be Pseudocapacitive?
2015 Standout
Continuous flow biocatalysis
2018
Flow Chemistry Syntheses of Styrenes, Unsymmetrical Stilbenes and Branched Aldehydes
2012
Emerging Droplet Microfluidics
2017 Standout
Controlled Flow Precipitation as a Valuable Tool for Synthesis
2015
Quasi-Homogeneous Photocatalysis in Ultrastiff Microporous Polymer Aerogels
2024 StandoutNobel
Iron(II)‐Catalyzed Direct Synthesis of NH Sulfoximines from Sulfoxides
2017
Anthraquinones As Pharmacological Tools and Drugs
2016 Standout
Biphasic Catalytic Hydrogen Peroxide Oxidation of Alcohols in Flow: Scale-up and Extraction
2016
Continuous flow hydrogenation of nitroarenes, azides and alkenes using maghemite–Pd nanocomposites
2015
A combination of natural deep eutectic solvents and microflow technology: a sustainable innovation for the tandem synthesis of 3-aminohexahydrocoumarins
2016
Photodecarboxylations in an Advanced Meso‐Scale Continuous‐Flow Photoreactor
2015
Exploring New Parameter Spaces for the Oxidative Homocoupling of Aniline Derivatives: Sustainable Synthesis of Azobenzenes in a Flow System
2015
New synthetic routes towards MOF production at scale
2017 Standout
Novel Process Windows for Enabling, Accelerating, and Uplifting Flow Chemistry
2013
The Use of Gases in Flow Synthesis
2015
Works of Bernhard Gutmann being referenced
Unusual behavior in the reactivity of 5-substituted-1H-tetrazoles in a resistively heated microreactor
2011
Microwave Chemistry in Silicon Carbide Reaction Vials: Separating Thermal from Nonthermal Effects
2009
Synthesis of 5‐Substituted 1H‐Tetrazoles from Nitriles and Hydrazoic Acid by Using a Safe and Scalable High‐Temperature Microreactor Approach
2010
Activation and Deactivation of a Chemical Transformation by an Electromagnetic Field: Evidence for Specific Microwave Effects in the Formation of Grignard Reagents
2011
A Two‐Step Continuous‐Flow Synthesis of N‐(2‐Aminoethyl)acylamides through Ring‐Opening/Hydrogenation of Oxazolines
2011
Sintered Silicon Carbide: A New Ceramic Vessel Material for Microwave Chemistry in Single‐Mode Reactors
2010
Continuous‐Flow Technology—A Tool for the Safe Manufacturing of Active Pharmaceutical Ingredients
2015 Standout
Characterization of Microwave‐Induced Electric Discharge Phenomena in Metal–Solvent Mixtures
2012
Shifting Chemical Equilibria in Flow—Efficient Decarbonylation Driven by Annular Flow Regimes
2014
Continuous‐Flow Synthesis of Adipic Acid from Cyclohexene Using Hydrogen Peroxide in High‐Temperature Explosive Regimes
2013
Toward the Synthesis of Noroxymorphone via Aerobic Palladium-Catalyzed Continuous Flow N-Demethylation Strategies
2016
Shifting Chemical Equilibria in Flow—Efficient Decarbonylation Driven by Annular Flow Regimes
2014
Microwave Chemistry in Silicon Carbide Reaction Vials: Separating Thermal from Nonthermal Effects
2009
The Concept of Chemical Generators: On-Site On-Demand Production of Hazardous Reagents in Continuous Flow
2020
Continuous Flow Synthesis of α-Halo Ketones: Essential Building Blocks of Antiretroviral Agents
2014
Laboratory-Scale Membrane Reactor for the Generation of Anhydrous Diazomethane
2016
Activation and Deactivation of a Chemical Transformation by an Electromagnetic Field: Evidence for Specific Microwave Effects in the Formation of Grignard Reagents
2011
One-Pot Synthesis of α-Haloketones Employing a Membrane-Based Semibatch Diazomethane Generator
2016
Kontinuierliche Durchflussverfahren: ein Werkzeug für die sichere Synthese von pharmazeutischen Wirkstoffen
2015
Homogeneous Liquid-Phase Oxidation of Ethylbenzene to Acetophenone in Continuous Flow Mode
2013
Safe Generation and Synthetic Utilization of Hydrazoic Acid in a Continuous Flow Reactor
2012
Development of a Continuous Flow Sulfoxide Imidation Protocol Using Azide Sources under Superacidic Conditions
2015
Continuous Flow Generation and Reactions of Anhydrous Diazomethane Using a Teflon AF-2400 Tube-in-Tube Reactor
2013
Continuous-Flow Electrophilic Amination of Arenes and Schmidt Reaction of Carboxylic Acids Utilizing the Superacidic Trimethylsilyl Azide/Triflic Acid Reagent System
2016
Process Intensified Flow Synthesis of 1H-4-Substituted Imidazoles: Toward the Continuous Production of Daclatasvir
2015
Safe generation and use of bromine azide under continuous flow conditions – selective 1,2-bromoazidation of olefins
2015
Continuous flow synthesis of β-amino acids from α-amino acids via Arndt–Eistert homologation
2014
Synthesis of 5‐Substituted 1H‐Tetrazoles from Nitriles and Hydrazoic Acid by Using a Safe and Scalable High‐Temperature Microreactor Approach
2010
On the Fischer Indole Synthesis of 7-Ethyltryptophol—Mechanistic and Process Intensification Studies under Continuous Flow Conditions
2013
Mechanistic Insights on Azide−Nitrile Cycloadditions: On the Dialkyltin Oxide−Trimethylsilyl Azide Route and a New Vilsmeier−Haack-Type Organocatalyst
2011
Continuous Flow Homolytic Aromatic Substitution with Electrophilic Radicals: A Fast and Scalable Protocol for Trifluoromethylation
2016
Batch‐ and Continuous‐Flow Aerobic Oxidation of 14‐Hydroxy Opioids to 1,3‐Oxazolidines—A Concise Synthesis of Noroxymorphone
2016