Standout Papers
Citation Impact
Citing Papers
Antibiotic Treatment Alters the Colonic Mucus Layer and Predisposes the Host to Exacerbated Citrobacter rodentium -Induced Colitis
2011
Antibiotic Treatment of Clostridium difficile Carrier Mice Triggers a Supershedder State, Spore-Mediated Transmission, and Severe Disease in Immunocompromised Hosts
2009
The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T reg Cell Homeostasis
2013 StandoutScience
Nod2 is required for the regulation of commensal microbiota in the intestine
2009
Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism
2009 StandoutScienceNobel
Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice
2012
Intestinal Microbiota Containing Barnesiella Species Cures Vancomycin-Resistant Enterococcus faecium Colonization
2013
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface
2008
Myofibroblasts and mechano-regulation of connective tissue remodelling
2002 Standout
Non-alcoholic fatty liver and the gut microbiota
2016
Endoplasmic reticulum stress and intestinal inflammation
2009
Regulation of C-type Lectin Antimicrobial Activity by a Flexible N-terminal Prosegment
2008
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Mucin dynamics and enteric pathogens
2011
NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice
2017
Mechanisms controlling pathogen colonization of the gut
2010
Innate IL-17-producing cells: the sentinels of the immune system
2010 Standout
Contributions of metabolic dysregulation and inflammation to nonalcoholic steatohepatitis, hepatic fibrosis, and cancer
2013
Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut
2008
Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells
2012
Liver fibrosis
2005 Standout
Changes of Intestinal Functions in Liver Cirrhosis
2016 Standout
Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans
2010
Toll-like receptors as targets in chronic liver diseases
2009
Mechanisms of hepatic stellate cell activation
2017 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function
2010
Preclinical models of non-alcoholic fatty liver disease
2017
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Epithelial antimicrobial defence of the skin and intestine
2012
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
Hepatic stellate cells primed with cytokines upregulate inflammation in response to peptidoglycan or lipoteichoic acid
2006
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
2012 StandoutNature
TLR4 enhances TGF-β signaling and hepatic fibrosis
2007 Standout
Microbiotal influence on T cell subset development
2011
Intestinal Epithelial Autophagy Is Essential for Host Defense against Invasive Bacteria
2013
NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis
2003
Changes in the Intestinal Microbiome and Alcoholic and Nonalcoholic Liver Diseases: Causes or Effects?
2016
Toll-like receptor 2 is critical for induction of Reg3β expression and intestinal clearance of Yersinia pseudotuberculosis
2009
Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
2009 Standout
Toll-Like Receptor 4 Mediates Alcohol-Induced Steatohepatitis Through Bone Marrow-Derived and Endogenous Liver Cells in Mice
2011
Toll-like receptors and cancer
2008
NF-κB in the regulation of epithelial homeostasis and inflammation
2010
Inhibition of inhibitor of κB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis
2005
The role of the intestinal microbiota in enteric infection
2009
Anandamide induces necrosis in primary hepatic stellate cells†‡
2005
Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating Kupffer cell polarization in mice
2011
Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis
2006
Role of the Microbiota in Immunity and Inflammation
2014 Standout
Role of the gut microbiota in immunity and inflammatory disease
2013 Standout
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
Molecular and cellular mechanisms of liver fibrosis and its regression
2020
Heritability of Hepatic Fibrosis and Steatosis Based on a Prospective Twin Study
2015
Inflammation-associated interleukin-6/signal transducer and activator of transcription 3 activation ameliorates alcoholic and nonalcoholic fatty liver diseases in interleukin-10–deficient mice
2011
The role of the gut microbiota in NAFLD
2016
Depletion of Murine Intestinal Microbiota: Effects on Gut Mucosa and Epithelial Gene Expression
2011
Functional interactions between the gut microbiota and host metabolism
2012 StandoutNature
Mechanisms of Hepatic Fibrogenesis
2008 Standout
Regulatory mechanisms of immune responses to intestinal bacteria
2009
Host Response to Translocated Microbial Products Predicts Outcomes of Patients With HBV or HCV Infection
2011
Immunity, Inflammation, and Cancer
2010 Standout
NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense
2012
Bacterial Flagellin Stimulates Toll‐Like Receptor 5–Dependent Defense against Vancomycin‐Resistant Enterococcus Infection
2010
Role of the Commensal Microbiota in Normal and Pathogenic Host Immune Responses
2011
Antibiotic-Induced Changes in the Intestinal Microbiota and Disease
2016
RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota
2011
Diet rapidly and reproducibly alters the human gut microbiome
2013 StandoutNature
Immune adaptations that maintain homeostasis with the intestinal microbiota
2010
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
2015 StandoutNature
Gut Commensal Bacteria Direct a Protective Immune Response against Toxoplasma gondii
2009
Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
2008 Standout
The Role of Matrix Stiffness in Hepatic Stellate Cell Activation and Liver Fibrosis
2005
Intestinal epithelial cells: regulators of barrier function and immune homeostasis
2014 Standout
Transient adenoviral gene transfer of Smad7 prevents injury-induced epithelial–mesenchymal transition of lens epithelium in mice
2004
Th17 and Regulatory T Cells in Mediating and Restraining Inflammation
2010
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis
2011
Telomere length in leukocytes correlates with bone mineral density and is shorter in women with osteoporosis
2007
Toll–Like Receptor 4 Mediates Inflammatory Signaling by Bacterial Lipopolysaccharide in Human Hepatic Stellate Cells
2003
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
Do symbiotic bacteria subvert host immunity?
2009
Characterization of fecal microbial communities in patients with liver cirrhosis
2011
Interleukin 23 Production by Intestinal CD103+CD11b+ Dendritic Cells in Response to Bacterial Flagellin Enhances Mucosal Innate Immune Defense
2012
Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2−/− mice
2009 StandoutNobel
Intestinal microbiota, evolution of the immune system and the bad reputation of pro-inflammatory immunity
2011
Mitochondria as multifaceted regulators of cell death
2019 Standout
Control of pathogens and pathobionts by the gut microbiota
2013
Cytokine-mediated regulation of antimicrobial proteins
2008
Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets
2011 Standout
NGM282 for treatment of non-alcoholic steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial
2018
Lipotoxic lethal and sublethal stress signaling in hepatocytes: relevance to NASH pathogenesis
2016
Translating an Understanding of the Pathogenesis of Hepatic Fibrosis to Novel Therapies
2013
Diversity, stability and resilience of the human gut microbiota
2012 StandoutNature
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
2013 StandoutNature
Like Will to Like: Abundances of Closely Related Species Can Predict Susceptibility to Intestinal Colonization by Pathogenic and Commensal Bacteria
2010
Microbes in Gastrointestinal Health and Disease
2008
Microbiota-mediated colonization resistance against intestinal pathogens
2013
Inflammasome activation and function in liver disease
2015
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Intraluminal Containment of Commensal Outgrowth in the Gut during Infection-Induced Dysbiosis
2013
Matrix Elasticity Directs Stem Cell Lineage Specification
2006 Standout
The human microbiome: at the interface of health and disease
2012 Standout
Metabolic and histological implications of intrahepatic triglyceride content in nonalcoholic fatty liver disease
2016
Gut Microbiota in Health and Disease
2010 Standout
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
Telomere length is paternally inherited and is associated with parental lifespan
2007 StandoutNobel
Interactions Between the Microbiota and the Immune System
2012 StandoutScience
Dialogue between E. coli free radical pathways and the mitochondria of C. elegans
2015 StandoutNobel
Tissue Cells Feel and Respond to the Stiffness of Their Substrate
2005 StandoutScience
Mechanisms of alcohol‐induced hepatic fibrosis
2006
DAMP-sensing receptors in sterile inflammation and inflammatory diseases
2019 Standout
Reproducible Community Dynamics of the Gastrointestinal Microbiota following Antibiotic Perturbation
2009
The PNPLA3 I148M variant modulates the fibrogenic phenotype of human hepatic stellate cells
2017
Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase
2013 StandoutNobel
Inflammasomes and Metabolic Disease
2013
Lipotoxicity and the gut-liver axis in NASH pathogenesis
2017
Inflammatory Bowel Disease
2010 Standout
The specificities of protein kinase inhibitors: an update
2003 Standout
Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
2007 Standout
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Liver Fibrosis: Mechanistic Concepts and Therapeutic Perspectives
2020
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
Intestinally Secreted C-Type Lectin Reg3b Attenuates Salmonellosis but Not Listeriosis in Mice
2012
An improved mouse model that rapidly develops fibrosis in non‐alcoholic steatohepatitis
2013
Nonalcoholic fatty liver disease is associated with an almost twofold increased risk of incident type 2 diabetes and metabolic syndrome. Evidence from a systematic review and meta‐analysis
2015
The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota
2015
Host-Gut Microbiota Metabolic Interactions
2012 StandoutScience
IL-22 Deficiency Alters Colonic Microbiota To Be Transmissible and Colitogenic
2013
The Microbiome in Infectious Disease and Inflammation
2012
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 StandoutNobel
Fresh Approaches to Anti-Infective Therapies
2012
Nonalcoholic Fatty Liver Disease
2015 Standout
Interactions of the Intestinal Epithelium with the Pathogen and the Indigenous Microbiota: A Three-Way Crosstalk
2008
Current status of novel antifibrotic therapies in patients with chronic liver disease
2011
Fast detection of liver fibrosis with collagen-binding single-nanometer iron oxide nanoparticles via T 1 -weighted MRI
2023 StandoutNobel
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
The Antibacterial Lectin RegIIIγ Promotes the Spatial Segregation of Microbiota and Host in the Intestine
2011 Science
Works of Bernd Schnabl being referenced
Association Between Quantity of Liver Fat and Cardiovascular Risk in Patients With Nonalcoholic Fatty Liver Disease Independent of Nonalcoholic Steatohepatitis
2015
TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells
2001
New mitochondrial DNA synthesis enables NLRP3 inflammasome activation
2018 Nature
Bacterial translocation and changes in the intestinal microbiome in mouse models of liver disease
2012
c-Jun N-terminal Kinase-1 From Hematopoietic Cells Mediates Progression From Hepatic Steatosis to Steatohepatitis and Fibrosis in Mice
2009
LPS-mediated NFκB activation varies between activated human hepatic stellate cells from different donors
2004
The Role of Smad3 in Mediating Mouse Hepatic Stellate Cell Activation
2001
Intestinal microbiota and nonalcoholic steatohepatitis
2017
Immortal Activated Human Hepatic Stellate Cells Generated by Ectopic Telomerase Expression
2002
Methods to determine intestinal permeability and bacterial translocation during liver disease
2015
The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91phox mediate hepatic fibrosis in mice
2011
Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice
2010
Enteric dysbiosis associated with a mouse model of alcoholic liver disease
2010
Effect of Weight Loss on Magnetic Resonance Imaging Estimation of Liver Fat and Volume in Patients With Nonalcoholic Steatohepatitis
2014
Up‐regulated eotaxin plasma levels in chronic liver disease patients indicate hepatic inflammation, advanced fibrosis and adverse clinical course
2006
Supplementation of Saturated Long-Chain Fatty Acids Maintains Intestinal Eubiosis and Reduces Ethanol-induced Liver Injury in Mice
2014
Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits
2008 Nature
Gliotoxin-mediated apoptosis of activated human hepatic stellate cells
2003
The Gut Microbiota and Liver Disease
2015
A TLR4/MD2 fusion protein inhibits LPS-induced pro-inflammatory signaling in hepatic stellate cells
2008
Replicative Senescence of Activated Human Hepatic Stellate Cells Is Accompanied by A Pronounced Inflammatory But Less Fibrogenic Phenotype
2003
Role of TLR9 in hepatic stellate cells and experimental liver fibrosis
2008
DNA Microarrays and Data Mining To Study Hepatic Fibrosis
2005
Interactions Between the Intestinal Microbiome and Liver Diseases
2014
Role of innate immunity and the microbiota in liver fibrosis: crosstalk between the liver and gut
2011
CD40 Activates NF-κB and c-Jun N-Terminal Kinase and Enhances Chemokine Secretion on Activated Human Hepatic Stellate Cells
2001
Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist
2012
Dysbiosis‐induced intestinal inflammation activates tumor necrosis factor receptor I and mediates alcoholic liver disease in mice
2014
MyD88-mediated signals induce the bactericidal lectin RegIIIγ and protect mice against intestinal Listeria monocytogenes infection
2007
TRAM2 Protein Interacts with Endoplasmic Reticulum Ca2+ Pump Serca2b and Is Necessary for Collagen Type I Synthesis
2004
Alcoholic Liver Disease: The Gut Microbiome and Liver Cross Talk
2015
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response
2009 StandoutNobel
Microbiota Protects Mice Against Acute Alcohol‐Induced Liver Injury
2015