Citation Impact
Citing Papers
Regulation of breathing by CO 2 requires the proton-activated receptor GPR4 in retrotrapezoid nucleus neurons
2015 Science
N-cadherin Gene Expression in Prostate Carcinoma Is Modulated by Integrin-Dependent Nuclear Translocation of Twist1
2006
HDL-bound sphingosine 1-phosphate acts as a biased agonist for the endothelial cell receptor S1P 1 to limit vascular inflammation
2015
An optimized transgenesis system for Drosophila using germ-line-specific φC31 integrases
2007 Standout
The NOTCH4 – HEY1 Pathway Induces Epithelial–Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma
2017
Ceramide 1-Phosphate Is Required for the Translocation of Group IVA Cytosolic Phospholipase A2 and Prostaglandin Synthesis
2009
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Hypoxia-Inducible Factor-1-Dependent Repression of E-cadherin in von Hippel-Lindau Tumor Suppressor–Null Renal Cell Carcinoma Mediated by TCF3, ZFHX1A, and ZFHX1B
2006 StandoutNobel
Human genetic disorders of sphingolipid biosynthesis
2014
HDL-bound sphingosine-1-phosphate restrains lymphopoiesis and neuroinflammation
2015 Nature
Vascular Development
2010
Osteoporosis
2019 Standout
Oral Fingolimod or Intramuscular Interferon for Relapsing Multiple Sclerosis
2010 Standout
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
2010 Standout
Cytosolic Phospholipase A2 and Lysophospholipids in Tumor Angiogenesis
2010
A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis
2010 Standout
Finding a way out: lymphocyte egress from lymphoid organs
2007
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
2008 Standout
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Multi-input chemical control of protein dimerization for programming graded cellular responses
2019 StandoutNobel
Sphingolipids and their metabolism in physiology and disease
2017 Standout
Guidance Molecules in Axon Regeneration
2010
Bone morphogenetic protein receptors and signal transduction
2009 Standout
IRAK‐4 kinase activity is required for IRAK‐4‐dependent innate and adaptive immune responses
2008
Low-Density Lipoprotein Receptor-Related Protein-1 Mediates Endocytic Clearance of Tissue Inhibitor of Metalloproteinases-1 and Promotes Its Cytokine-Like Activities
2014 StandoutNobel
Lymphangiogenesis: Molecular Mechanisms and Future Promise
2010 Standout
Pattern Recognition Receptors and Inflammation
2010 Standout
Arrestin Development: Emerging Roles for β-arrestins in Developmental Signaling Pathways
2009 StandoutNobel
IgE and mast cells in allergic disease
2012 Standout
Single-spike detection in vitro and in vivo with a genetic Ca2+ sensor
2008 StandoutNobel
DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells
2005 Standout
Sequential control of Toll-like receptor–dependent responses by IRAK1 and IRAK2
2008
New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer
2018 Standout
Complex networks orchestrate epithelial–mesenchymal transitions
2006 Standout
Role of transforming growth factor-β superfamily signaling pathways in human disease
2008
Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer
2012
Transcriptional regulation of cadherins during development and carcinogenesis
2004
The Immunomodulator FTY720 Has a Direct Cytoprotective Effect in Oligodendrocyte Progenitors
2007
Intracellular Toll-like Receptors
2010 StandoutNobel
WNT signaling in bone homeostasis and disease: from human mutations to treatments
2013 Standout
Road to precision: recombinase-based targeting technologies for genome engineering
2007
IRAK1: A critical signaling mediator of innate immunity
2007
Sphingosine Kinases Are Not Required for Inflammatory Responses in Macrophages
2013
The actin gene family: Function follows isoform
2010
Therapeutic opportunities for manipulating TReg cells in autoimmunity and cancer
2012
Cellular and Molecular Basis of Pulmonary Arterial Hypertension
2009
FTY720 (fingolimod) in Multiple Sclerosis: therapeutic effects in the immune and the central nervous system
2009
Remodelling the extracellular matrix in development and disease
2014 Standout
Sphingosine-1-phosphate in chronic intestinal inflammation and cancer
2013
Building strong bones: molecular regulation of the osteoblast lineage
2011
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
2007 Standout
Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice
2008
Maternal disturbance in activated sphingolipid metabolism causes pregnancy loss in mice
2007
Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions
2008
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
2008 Standout
Membrane lipids: where they are and how they behave
2008 Standout
Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis
2010
Lysophospholipid receptors: Signalling, pharmacology and regulation by lysophospholipid metabolism
2006
Sphingosine 1-phosphate receptors in health and disease: Mechanistic insights from gene deletion studies and reverse pharmacology
2007
LPS/TLR4 signal transduction pathway
2008 Standout
Stromal inactivation of BMPRII leads to colorectal epithelial overgrowth and polyp formation
2007
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
Next Generation Sequencing Analysis of Human Platelet PolyA+ mRNAs and rRNA-Depleted Total RNA
2013 StandoutNobel
Mitochondrial TCA cycle metabolites control physiology and disease
2020 Standout
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
2014 Standout
FGF-23 and secondary hyperparathyroidism in chronic kidney disease
2013
Spinster Homolog 2 (Spns2) Deficiency Causes Early Onset Progressive Hearing Loss
2014
Combinatorial Signal Perception in the BMP Pathway
2017
The acute respiratory distress syndrome
2012 Standout
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Localization and function of cytosolic phospholipase A2α at the Golgi
2010
Toll‐like receptors control autophagy
2008
Sphingosine 1-phosphate in coagulation and inflammation
2011
Chronic Kidney Disease
2016 Standout
Structure–activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors
2008
Regulatory networks defining EMT during cancer initiation and progression
2013 Standout
Brain Penetration of the Oral Immunomodulatory Drug FTY720 and Its Phosphorylation in the Central Nervous System during Experimental Autoimmune Encephalomyelitis: Consequences for Mode of Action in Multiple Sclerosis
2007
Hypoxia Attenuates the Expression of E-Cadherin via Up-Regulation of SNAIL in Ovarian Carcinoma Cells
2003
Mechanisms of implantation: strategies for successful pregnancy
2012 Standout
LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling
2013 StandoutNature
An Emerging Role for the Lipid Mediator Sphingosine-1-Phosphate in Mast Cell Effector Function and Allergic Disease
2011
MECHANISMS IN ENDOCRINOLOGY: Genetics of human bone formation
2017
Digoxin inhibits development of hypoxic pulmonary hypertension in mice
2012 StandoutNobel
LDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin
2012
RBPjκ-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development
2010 StandoutNobel
Genetic Ablation of the Bmpr2 Gene in Pulmonary Endothelium Is Sufficient to Predispose to Pulmonary Arterial Hypertension
2008
Crosstalk Between Vascular Endothelial Growth Factor, Notch, and Transforming Growth Factor-β in Vascular Morphogenesis
2008
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
2008 StandoutNature
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Notch and the Skeleton
2009
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Sphingosine-1-Phosphate Transporters as Targets for Cancer Therapy
2014
Drugging Sphingosine Kinases
2014
Role for sphingosine kinase 1 in colon carcinogenesis
2008
Complementary roles of gasotransmitters CO and H2S in sleep apnea
2017 StandoutNobel
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
A novel modifier of regulatory T cells
2009 StandoutNobel
Palaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne
2016 StandoutNobel
Site-Specific Transformation of Drosophila via ϕC31 Integrase-Mediated Cassette Exchange
2006
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
De novo design of protein logic gates
2020 StandoutScienceNobel
A Point Mutation in the Amino Terminus of TLR7 Abolishes Signaling without Affecting Ligand Binding
2011 StandoutNobel
Chemical proteomic map of dimethyl fumarate–sensitive cysteines in primary human T cells
2016
The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors
2006
Works of Bernd Kinzel being referenced
FGF receptors control vitamin D and phosphate homeostasis by mediating renal FGF-23 signaling and regulating FGF-23 expression in bone
2011
Wild-type levels of ceramide and ceramide-1-phosphate in the retina of ceramide kinase-like-deficient mice
2008
IRAK-4 Kinase Activity Is Required for Interleukin-1 (IL-1) Receptor- and Toll-like Receptor 7-mediated Signaling and Gene Expression
2007
Strong and ubiquitous expression of transgenes targeted into the β-actin locus by Cre/lox cassette replacement
2005
Analysis of regulatory elements of E‐cadherin with reporter gene constructs in transgenic mouse embryos
2003
Inhibitory Activity of Myelin-Associated Glycoprotein on Sensory Neurons Is Largely Independent of NgR1 and NgR2 and Resides within Ig-Like Domains 4 and 5
2009
Ubiquitous overexpression of Hey1 transcription factor leads to osteopenia and chondrocyte hypertrophy in bone
2009
Reduced pathological angiogenesis and tumor growth in mice lacking GPR4, a proton sensing receptor
2011
Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension
2015
Flow-Regulated Endothelial S1P Receptor-1 Signaling Sustains Vascular Development
2012
Sphingosine kinase type 2 is essential for lymphopenia induced by the immunomodulatory drug FTY720
2005
Neutropenia with Impaired Immune Response to Streptococcus pneumoniae in Ceramide Kinase-Deficient Mice
2008
Disruption of Lrp4 function by genetic deletion or pharmacological blockade increases bone mass and serum sclerostin levels
2014
Dosage-dependent requirement of BMP type II receptor for maintenance of vascular integrity
2007