Citation Impact
Citing Papers
Regulation of nuclear-cytoplasmic partitioning by the lin-28 - lin-46 pathway reinforces microRNA repression of HBL-1 to confer robust cell-fate progression in C. elegans
2019 StandoutNobel
Human disease locus discovery and mapping to molecular pathways through phylogenetic profiling
2013 StandoutNobel
S-Nitrosylation of β-Arrestin Regulates β-Adrenergic Receptor Trafficking
2008 StandoutNobel
Molybdenum cofactor and human disease
2016
Comparative Genomics Analysis of the Metallomes
2012
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Protein-bound molybdenum cofactor is bioavailable and rescues molybdenum cofactor-deficient C. elegans
2021 StandoutNobel
Rethinking amide bond synthesis
2011 StandoutNature
High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis
2013 StandoutNobel
Drug-Induced Liver Injury in Humans: The Case of Ximelagatran
2009
Prodrug Strategies in Anticancer Chemotherapy
2007
NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential
2006
Pharmacological actions of a novel NO‐independent guanylyl cyclase stimulator, BAY 41‐8543: in vitro studies
2002
Drug-Induced Hepatotoxicity
2003 Standout
Psoriasis
2021 Standout
A Self‐Sufficient Peroxide‐Driven Hydroxylation Biocatalyst
2003 StandoutNobel
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
The great diversity of reactions catalyzed by cytochromes P450
1998
S-nitrosoglutathione inhibits α1-adrenergic receptor-mediated vasoconstriction and ligand binding in pulmonary artery
2005
Nitric oxide synthase is a cytochrome P-450 type hemoprotein
1992
Non-alcoholic fatty liver disease
2021 Standout
YcbX and yiiM, two novel determinants for resistance of Escherichia coli to N‐hydroxylated base analogues
2008
Glial and neuronal control of brain blood flow
2010 StandoutNature
Fluorescent indicators based on BODIPY
2011 Standout
Crystal structure of the hydroxylaminopurine resistance protein, YiiM, and its putative molybdenum cofactor-binding catalytic site
2018
Molybdenum cofactor deficiency: Mutations in GPHN, MOCS1, and MOCS2
2010
Enzymatic functionalization of carbon–hydrogen bonds
2010 StandoutNobel
Drug discovery chemistry: a primer for the non-specialist
2009
The Discovery of furo[2,3-c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors
2010
Catalysis by nitric oxide synthase
1998
Toward Genetic Prediction of Nonalcoholic Fatty Liver Disease Trajectories: PNPLA3 and Beyond
2020
Molybdenum cofactors, enzymes and pathways
2009 Nature
Structure-based maximal affinity model predicts small-molecule druggability
2007
Neuronal Nitric Oxide Synthase Self-inactivates by Forming a Ferrous-Nitrosyl Complex during Aerobic Catalysis
1995 StandoutNobel
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
Physiological functions of mineral micronutrients (Cu, Zn, Mn, Fe, Ni, Mo, B, Cl)
2009 Standout
Predicting drug metabolism: experiment and/or computation?
2015
Prodrugs: design and clinical applications
2008
Models and mechanisms of O‐O bond activation by cytochrome P450
2004
PhyloGene server for identification and visualization of co-evolving proteins using normalized phylogenetic profiles
2015 StandoutNobel
A Metal‐Free Transfer Hydrogenation: Organocatalytic Conjugate Reduction of α,β‐Unsaturated Aldehydes
2004 StandoutNobel
Inducible nitric oxide synthase from a rat alveolar macrophage cell line is inhibited by nitric oxide.
1993 StandoutNobel
Ionic-Liquid-Mediated Extraction and Separation Processes for Bioactive Compounds: Past, Present, and Future Trends
2017 Standout
Biochemistry of Nitric Oxide and Its Redox-Activated Forms
1992 StandoutScience
3d Transition Metals for C–H Activation
2018 Standout
1993
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Bioimaging of Nitric Oxide
2002
Structure and Nanostructure in Ionic Liquids
2015 Standout
Reduced cGMP signaling associated with neointimal proliferation and vascular dysfunction in late-stage atherosclerosis
2004
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Luminescent Chemodosimeters for Bioimaging
2012 Standout
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Covalent Modifiers: An Orthogonal Approach to Drug Design
2009
Chem-Bioinformatics and QSAR: A Review of QSAR Lacking Positive Hydrophobic Terms
2001 Standout
The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
2011 Standout
Oral Rivaroxaban for Symptomatic Venous Thromboembolism
2010 Standout
Enantioselective Reduction of Electrophilic CC Bonds with sodium tetrahydroborate and ‘semicorrin’ cobalt catalysts
1996
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Common and Uncommon Cytochrome P450 Reactions Related to Metabolism and Chemical Toxicity
2001
Nitrate Tolerance
2002
Use of Lawesson's Reagent in Organic Syntheses
2007 Standout
Mobile Magnetic Nanocatalysts for Bioorthogonal Targeted Cancer Therapy
2018
Comparative QSAR: Radical Reactions of Benzene Derivatives in Chemistry and Biology
1997
Fluorescent Sensors for Measuring Metal Ions in Living Systems
2014 Standout
N-Oxygenation of Primary Amines and Hydroxylamines and Retroreduction of Hydroxylamines by Adult Human Liver Microsomes and Adult Human Flavin-Containing Monooxygenase 3
1996
Role of cGMP versus 20-HETE in the vasodilator response to nitric oxide in rat cerebral arteries
2000
N-Aryl N‘-Hydroxyguanidines, A New Class of NO-Donors after Selective Oxidation by Nitric Oxide Synthases: Structure−Activity Relationship
2001
Prodrug ionic liquids: functionalizing neutral active pharmaceutical ingredients to take advantage of the ionic liquid form
2013
Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed nitric oxide from L-arginine.
1993 StandoutNobel
Drug specific, tuning of an ionic liquid's hydrophilic–lipophilic balance to improve water solubility of poorly soluble active pharmaceutical ingredients
2013
Luminescent metal–organic frameworks for chemical sensing and explosive detection
2014 Standout
Chemistry of Biologically Important Synthetic Organoselenium Compounds
2001 Standout
P-450 Metabolites of Arachidonic Acid in the Control of Cardiovascular Function
2002
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
The Mononuclear Molybdenum Enzymes
2014 Standout
Chemoenzymatic elaboration of monosaccharides using engineered cytochrome P450 BM3 demethylases
2009 StandoutNobel
Nitric oxide inhibits neuronal nitric oxide synthase by interacting with the heme prosthetic group. Role of tetrahydrobiopterin in modulating the inhibitory action of nitric oxide.
1994 StandoutNobel
A review of the mechanisms of action of dimethylfumarate in the treatment of psoriasis
2018
Gold-Catalyzed Carbon−Heteroatom Bond-Forming Reactions
2011 Standout
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
Mechanism of Oxidation Reactions Catalyzed by Cytochrome P450 Enzymes
2004 Standout
Co(acac)2/O2-Mediated Oxidative Isocyanide Insertion with 2-Aryl Anilines: Efficient Synthesis of 6-Amino Phenanthridine Derivatives
2014
Design Strategies for Water-Soluble Small Molecular Chromogenic and Fluorogenic Probes
2013 Standout
Gold(I)-Catalyzed Tandem Reactions Initiated by Hydroamination of Alkynyl Carbamates: Application to the Synthesis of Nitidine
2009
Enzyme-Controlled Nitrogen-Atom Transfer Enables Regiodivergent C–H Amination
2014 StandoutNobel
Gold(I)-Catalyzed Activation of Alkynes for the Construction of Molecular Complexity
2015 Standout
The natural polyamine spermine functions directly as a free radical scavenger
1998 Standout
Structure and Chemistry of Cytochrome P450
2005 Standout
Works of Bernd Clement being referenced
Crystal structure of human mARC1 reveals its exceptional position among eukaryotic molybdenum enzymes
2018
The reduction of 6-N-hydroxylaminopurine to adenine by xanthine oxidase
1992
Characterization of in Vitro Biotransformation of New, Orally Active, Direct Thrombin Inhibitor Ximelagatran, an Amidoxime and Ester Prodrug
2003
The mammalian molybdenum enzymes of mARC
2014
Mechanism of the microsomal N-hydroxylation of para-substituted benzamidines
1988
Biochemical and Spectroscopic Characterization of the Human Mitochondrial Amidoxime Reducing Components hmARC-1 and hmARC-2 Suggests the Existence of a New Molybdenum Enzyme Family in Eukaryotes
2010
Oxygen-insensitive enzymatic reduction of oximes to imines
2005
Cytochrome P450 dependent N-hydroxylation of a guanidine (debrisoquine), microsomal catalysed reduction and further oxidation of the N-hydroxy-guanidine metabolite to the urea derivative
1993
On the mechanism of nitric oxide formation upon oxidative cleavage of CN(OH) bonds by NO-synthases and cytochromes P450
1995
Defining the Role of the NADH–Cytochrome-b5 Reductase 3 in the Mitochondrial Amidoxime Reducing Component Enzyme System
2016
A Two‐Step Synthesis of Cytostatically Active Benzo[c]phenanthridine Derivatives
2004
Hepatic microsomal N-hydroxylation of adenine to 6-N-hydroxylaminopurine
1990
Identification of the Missing Component in the Mitochondrial Benzamidoxime Prodrug-converting System as a Novel Molybdenum Enzyme
2006
The fourth mammalian molybdenum enzyme mARC: current state of research
2011
Reduction of N-Hydroxy-sulfonamides, Including N-Hydroxy-valdecoxib, by the Molybdenum-Containing Enzyme mARC
2010
Isolation and Characterization of the Protein Components of the Liver Microsomal O2-insensitive NADH-Benzamidoxime Reductase
1997
The Involvement of Mitochondrial Amidoxime Reducing Components 1 and 2 and Mitochondrial Cytochrome b5 in N-Reductive Metabolism in Human Cells
2013
The Soluble Guanylyl Cyclase Inhibitor 1H-[1,2,4]Oxadiazolo[4,3,-a]quinoxalin-1-one Is a Nonselective Heme Protein Inhibitor of Nitric Oxide Synthase and Other Cytochrome P-450 Enzymes Involved in Nitric Oxide Donor Bioactivation
1999
REDUCTION OFN-HYDROXYLATED COMPOUNDS: AMIDOXIMES (N-HYDROXYAMIDINES) AS PRO-DRUGS OF AMIDINES
2002
The Pharmacokinetics of Fumaric Acid Esters Reveal Their In Vivo Effects
2017
Pharmacokinetics of anti-psoriatic fumaric acid esters in psoriasis patients
2010
Detection of fumarate–glutathione adducts in the portal vein blood of rats: evidence for rapid dimethylfumarate metabolism
2013
The Fourth Molybdenum Containing Enzyme mARC: Cloning and Involvement in the Activation ofN-Hydroxylated Prodrugs
2008
Lessons Learned from Marketed and Investigational Prodrugs
2004
Alkylierung und aminomethylierung von α-sulfinylsulfonen
1979
Microsomal Cytochrome P450 Dependent Oxidation of N-Hydroxyguanidines, Amidoximes, and Ketoximes: Mechanism of the Oxidative Cleavage of Their CN(OH) Bond with Formation of Nitrogen Oxides
1998
The Mitochondrial Amidoxime Reducing Component (mARC) Is Involved in Detoxification of N-Hydroxylated Base Analogues
2012
Synthesis and Biological Evaluation of 11-Substituted 6-Aminobenzo[c]phenanthridine Derivatives, a New Class of Antitumor Agents
2005
In Vivo Spin Trapping of Glyceryl Trinitrate–Derived Nitric Oxide in Rabbit Blood Vessels and Organs
1995
Reduction ofNω-hydroxy-L -arginine by the mitochondrial amidoxime reducing component (mARC)
2010
15N‐NMR‐Studien an 2‐Hydroxyguanidinen und Amidoximen
1985
15N‐NMR‐Studien der Tautomerie in N‐monosubstituierten Amidinen und in N,N′‐Diphenylguanidin
1986