Citation Impact
Citing Papers
The PKC/NF-κB Signaling Pathway Induces APOBEC3B Expression in Multiple Human Cancers
2015
A BOILED‐Egg To Predict Gastrointestinal Absorption and Brain Penetration of Small Molecules
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Expansive discovery of chemically diverse structured macrocyclic oligoamides
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Heparin-Protein Interactions
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The heparanome and regulation of cell function: structures, functions and challenges
2008
DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants
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Predicting Oral Absorption and Bioavailability
2003
Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib
2010
The influence of drug-like concepts on decision-making in medicinal chemistry
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Glycosaminoglycan-protein interactions: definition of consensus sites in glycosaminoglycan binding proteins
1998
Protein promiscuity and its implications for biotechnology
2009
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
2009
The influence of lipophilicity in drug discovery and design
2012
Heparin and heparan sulfate: structure and function
2002
Diversity-oriented synthesis; a spectrum of approaches and results
2008
PLIP: fully automated protein–ligand interaction profiler
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Defensins: antimicrobial peptides of innate immunity
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Transition-metal mediated carbon–sulfur bond activation and transformations
2012 Standout
Physicochemical Profiling (Solubility, Permeability and Charge State)
2001
An Expanded Set of Amino Acid Analogs for the Ribosomal Translation of Unnatural Peptides
2007 StandoutNobel
Investigating the Motion of Diblock Copolymer Assemblies in Ionic Liquids by In Situ Electron Microscopy
2012
Prediction of intestinal permeability
2002
Fibroblast growth factor signalling: from development to cancer
2010 Standout
An overview on 5α-reductase inhibitors
2009
Sofosbuvir Inhibits Hepatitis E Virus Replication In Vitro and Results in an Additive Effect When Combined With Ribavirin
2015 StandoutNobel
Physiochemical drug properties associated with in vivo toxicological outcomes
2008
The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans
2021 StandoutNobel
From carbohydrate leads to glycomimetic drugs
2009
DNA binds neutrophil elastase and mucus proteinase inhibitor and impairs their functional activity
1995
Analysis of Pharmacology Data and the Prediction of Adverse Drug Reactions and Off‐Target Effects from Chemical Structure
2007
ProTox: a web server for the in silico prediction of rodent oral toxicity
2014
Large-scale prediction and testing of drug activity on side-effect targets
2012 Nature
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
Effect of polyethyleneglycol (PEG) chain length on the bio–nano-interactions between PEGylated lipid nanoparticles and biological fluids: from nanostructure to uptake in cancer cells
2013
Decision trees to characterise the roles of permeability and solubility on the prediction of oral absorption
2014
Benzhydrylquinazolinediones: Novel cytosolic phospholipase A2α inhibitors with improved physicochemical properties
2009
Drug Promiscuity in PDB: Protein Binding Site Similarity Is Key
2013
Deep learning in neural networks: An overview
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NF-κB, inflammation, immunity and cancer: coming of age
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Multicomponent reactions for the synthesis of pyrroles
2010 Standout
Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates
2014
Targeting the Achilles Heel of Multidrug-Resistant Cancer by Exploiting the Fitness Cost of Resistance
2014
Revisiting the General Solubility Equation: In Silico Prediction of Aqueous Solubility Incorporating the Effect of Topographical Polar Surface Area
2011
3d Transition Metals for C–H Activation
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Fluorine in medicinal chemistry
2007 Standout
Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer
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Orthogonal Design of Experiments for Engineering of Lipid Nanoparticles for mRNA Delivery to the Placenta
2023 StandoutNobel
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Electropolymerization of a Cyclometalated Terthiophene: A Hybrid Material with a Palladium−Carbon Bond to the Backbone
2000
Structure and Nanostructure in Ionic Liquids
2015 Standout
Comparative study of the N-isobutyl-(2E,6Z)-dodecadienamide chemical and electrochemical syntheses
2008
Molecular Properties That Influence the Oral Bioavailability of Drug Candidates
2002 Standout
Antiadhesion Therapy for Urinary Tract Infections—A Balanced PK/PD Profile Proved To Be Key for Success
2012
Deep Architectures and Deep Learning in Chemoinformatics: The Prediction of Aqueous Solubility for Drug-Like Molecules
2013
Electropolymerization of Pd(II) Complexes Containing Phosphinoterthiophene Ligands
2001
Accessing Drug Metabolites via Transition‐Metal Catalyzed C−H Oxidation: The Liver as Synthetic Inspiration
2016
Heparin protects cathepsin G against inhibition by protein proteinase inhibitors.
1994
Oxadiazoles in Medicinal Chemistry
2011 Standout
Aggregation-Induced Emission: Together We Shine, United We Soar!
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Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
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Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis in the Last Decade
2018
Systematic analysis of gene properties influencing organ system phenotypes in mammalian perturbations
2014
Comprehensive physicochemical, pharmacokinetic and activity profiling of anti-TB agents
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The development of anticancer ruthenium(ii ) complexes: from single molecule compounds to nanomaterials
2017 Standout
ProTox-II: a webserver for the prediction of toxicity of chemicals
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A sulfated metabolite produced bystf3negatively regulates the virulence ofMycobacteriumtuberculosis
2006 StandoutNobel
SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules
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Fluorine in Pharmaceuticals: Looking Beyond Intuition
2007 StandoutScience
Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective
2010 Standout
Fluorescent Sensors for Measuring Metal Ions in Living Systems
2014 Standout
Aluminium fluorescence detection with a FRET amplified chemosensorElectronic supplementary information (ESI) available: experimental details and spectra. See http://www.rsc.org/suppdata/cc/b3/b303195k/
2003
Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance
2017 Standout
Model Complexes for Metallated Polythiophenes: Gold(I) and Palladium(II) Complexes of Bis(diphenylphosphino)oligothiophenes
2003
S-Glycosyl Primary Sulfonamides−A New Structural Class for Selective Inhibition of Cancer-Associated Carbonic Anhydrases
2009
ETCM: an encyclopaedia of traditional Chinese medicine
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Functional Oligothiophenes: Molecular Design for Multidimensional Nanoarchitectures and Their Applications
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The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
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Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties
2021 Standout
Conformational Effects on the Passive Membrane Permeability of Synthetic Macrocycles
2022
Discovery of a β-d -2′-Deoxy-2′-α-fluoro-2′-β-C-methyluridine Nucleotide Prodrug (PSI-7977) for the Treatment of Hepatitis C Virus
2010
Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps
2010 Standout
CNS Drug Design: Balancing Physicochemical Properties for Optimal Brain Exposure
2014
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Silver(I)−Thiophene π Interaction in the Assembly of Coordination Networks with the Supramolecular Synthons R−C⋮C⊃Agn (R = 2- or 3-thienyl; n = 4)
2007
Functions of Cell Surface Heparan Sulfate Proteoglycans
1999 Standout
Discovery and Investigation of Anticancer Ruthenium–Arene Schiff-Base Complexes via Water-Promoted Combinatorial Three-Component Assembly
2014
Improving Drug Candidates by Design: A Focus on Physicochemical Properties As a Means of Improving Compound Disposition and Safety
2011
Design Strategies for Water-Soluble Small Molecular Chromogenic and Fluorogenic Probes
2013 Standout
Discovery of Selective and Orally Bioavailable Protein Kinase Cθ (PKCθ) Inhibitors from a Fragment Hit
2014
Barrier-Independent, Fitness-Associated Differences in Sofosbuvir Efficacy against Hepatitis C Virus
2016 StandoutNobel
Increasing small molecule drug developability in sub-optimal chemical space
2013
Organophosphorus π-Conjugated Materials
2006 Standout
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout
Generation of Anti-trypanosomal Agents through Concise Synthesis and Structural Diversification of Sesquiterpene Analogues
2011 StandoutNobel
Works of Bernard Faller being referenced
Computational approaches to determine drug solubility
2007
Finasteride: A slow-binding 5.alpha.-reductase inhibitor
1993
Evolution of the physicochemical properties of marketed drugs: can history foretell the future?
2011
PAMPA—critical factors for better predictions of absorption
2007
Modeling Promiscuity Based on in vitro Safety Pharmacology Profiling Data
2007
What is modulating solubility in simulated intestinal fluids?
2010
Artificial Membrane Assays to Assess Permeability
2008
Coexistence of passive and carrier-mediated processes in drug transport
2010
Alkylamides from Echinacea Are a New Class of Cannabinomimetics
2006
Heparin-induced conformational change and activation of mucus proteinase inhibitor
1992
Evidence-based approach to assess passive diffusion and carrier-mediated drug transport
2012
Improving the Oral Bioavailability of the Iron Chelator HBED by Breaking the Symmetry of the Intramolecular H-Bond Network
2000
Passive Lipoidal Diffusion and Carrier-Mediated Cell Uptake Are Both Important Mechanisms of Membrane Permeation in Drug Disposition
2014
4-[3,5-Bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]- benzoic Acid: A Novel Efficient and Selective Iron(III) Complexing Agent
1999
High-Throughput Permeability pH Profile and High-Throughput Alkane/Water logPwith Artificial Membranes
2001
Structure–Activity Relationship and Pharmacokinetic Studies of Sotrastaurin (AEB071), a Promising Novel Medicine for Prevention of Graft Rejection and Treatment of Psoriasis
2011
High-Throughput Lipophilicity Measurement with Immobilized Artificial Membranes
2005
Metabolic Soft Spot Identification and Compound Optimization in Early Discovery Phases Using MetaSite and LC-MS/MS Validation
2008