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2014 Standout
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Snapshot of the Palladium(II)‐Catalyzed Oxidative Biaryl Bond Formation by X‐ray Analysis of the Intermediate Diaryl Palladium(II) Complex
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Recent advances in aryl–aryl bond formation by direct arylation
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On the Importance of an Acid Additive in the Synthesis of Pyrido[1,2‐a]benzimidazoles by Direct Copper‐Catalyzed Amination
2011
The imidazo[1,2-a]pyridine ring system as a scaffold for potent dual phosphoinositide-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitors
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Easily Accessible Auxiliary for Palladium‐Catalyzed Intramolecular Amination of C(sp2)H and C(sp3)H Bonds at δ‐ and ε‐Positions
2014
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2009
Copper‐Mediated Coupling of 1,1‐Dibromo‐1‐alkenes with Nitrogen Nucleophiles: A General Method for the Synthesis of Ynamides
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Carbonates: Ecofriendly Solvents for Palladium‐Catalyzed Direct 2‐Arylation of Oxazole Derivatives
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Rhodium‐Catalyzed Direct CH Amination of Benzamides with Aryl Azides: A Synthetic Route to Diarylamines
2012
A General Catalyst for the β‐Selective C–H Bond Arylation of Thiophenes with Iodoarenes
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Pd-catalysed regioselective C–H functionalisation of 2-pyrones
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The Cross‐Dehydrogenative Coupling of CH Bonds: A Versatile Strategy for CC Bond Formations
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Transition metal-catalyzed arylation of unactivated C(sp3)–H bonds
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Importance of palladium–carbon bond energies in direct arylation of polyfluorinated benzenes
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Palladium-catalyzed direct oxidative Heck–Cassar–Sonogashira type alkynylation of indoles with alkynes under oxygen
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2011
Direct Borylation of Primary CH Bonds in Functionalized Molecules by Palladium Catalysis
2014
Design and Enantioselective Synthesis of Cashmeran Odorants by Using “Enol Catalysis”
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Transition‐Metal‐Catalyzed Direct Arylation of (Hetero)Arenes by CH Bond Cleavage
2009 Standout
Cross Dehydrogenative Arylation (CDA) of a Benzylic CH Bond with Arenes by Iron Catalysis
2009
Palladium‐Catalyzed C(sp3)H Activation: A Facile Method for the Synthesis of 3,4‐Dihydroquinolinone Derivatives
2014
CH Bond Functionalization in Water Catalyzed by Carboxylato Ruthenium(II) Systems
2010
A Direct CH/ArH Coupling Approach to Oxindoles, Thio‐oxindoles, 3,4‐Dihydro‐1 H‐quinolin‐2‐ones, and 1,2,3,4‐Tetrahydroquinolines
2014
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2011
Decarboxylative CH Cross‐Coupling of Azoles
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Direct palladium-catalysed C–H arylation of BODIPY dyes at the 3- and 3,5-positions
2012
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2012
Carboxylate Ligand-Induced Intramolecular C−H Bond Activation of Iridium Complexes withN-Phenylperimidine-Based Carbene Ligands
2010
Programmed synthesis of arylthiazoles through sequential C–H couplings
2013
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
Synthesis of Condensed Heteroaromatic Compounds by Palladium-Catalyzed Oxidative Coupling of Heteroarene Carboxylic Acids with Alkynes
2009
Direct Arylation of Simple Azoles Catalyzed by 1,10-Phenanthroline Containing Palladium Complexes: An Investigation of C4 Arylation of Azoles and the Synthesis of Triarylated Azoles by Sequential Arylation
2011
Direct C−H Arylation of Electron-Deficient Heterocycles with Arylboronic Acids
2010
Construction of Heterocycle Scaffolds via Transition Metal‐ Catalyzed sp2 CH Functionalization
2009
Gold(I)-catalyzed [4+2] cycloaddition of N-(hex-5-enynyl) tert-butyloxycarbamates
2008
Pd-Catalyzed β-Selective Direct C–H Bond Arylation of Thiophenes with Aryltrimethylsilanes
2012
3d Transition Metals for C–H Activation
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Ring-opening, cycloaddition and rearrangement reactions of nitrogen-substituted cyclopropane derivatives
2016
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2011
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2009
Cu and Cu-Based Nanoparticles: Synthesis and Applications in Catalysis
2016 Standout
Electroreductive Intramolecular Coupling of Phthalimides with Aromatic Aldehydes: Application to the Synthesis of Lennoxamine
2011
Ruthenium-Catalyzed [2 + 2] Cycloadditions of Ynamides
2005
Palladium-Catalyzed Aerobic Oxidative Cross-Coupling Reactions of Terminal Alkynes with Alkylzinc Reagents
2010
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2012
Copper(II)-Mediated Intermolecular C(sp2)–H Amination of Benzamides with Electron-Rich Anilines
2016
Introduction of a Crystalline, Shelf-Stable Reagent for the Synthesis of Sulfur(VI) Fluorides
2018
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2010
Recent advances in the synthesis of (hetero)aryl-substituted heteroarenes via transition metal-catalysed direct (hetero)arylation of heteroarene C–H bonds with aryl halides or pseudohalides, diaryliodonium salts, and potassium aryltrifluoroborates
2009
Organic Photoredox Catalysis
2016 Standout
Palladium-Catalyzed Annulation of Arynes byo-Halobenzamides: Synthesis of Phenanthridinones
2012
Dehydrogenative [4 + 2] Cycloaddition of Formamides with Alkynes through Double C−H Activation
2011
Fused Ring Construction around Pyrrole, Indole, and Related Compounds via Palladium-Catalyzed Oxidative Coupling with Alkynes
2009
Palladium-Catalyzed Aryl–Aryl Bond Formation Through Double C–H Activation
2009
Oxidative coupling reactions for the functionalisation of C–H bonds using oxygen
2014
Directed Evolution: Bringing New Chemistry to Life
2017 StandoutNobel
Synthesis of (2-Oxoindolin-3-ylidene)methyl Acetates Involving a C−H Functionalization Process
2008
C−C Coupling of Benzyl Fluorides Catalyzed by an Electrophilic Phosphonium Cation
2016
Synthesis of Condensed Pyrroloindoles via Pd-Catalyzed Intramolecular C−H Bond Functionalization of Pyrroles
2008
Computational Studies of Carboxylate-Assisted C–H Activation and Functionalization at Group 8–10 Transition Metal Centers
2017
Benzenesulfonyl chlorides: new reagents for access to alternative regioisomers in palladium-catalysed direct arylations of thiophenes
2013
C–H Arylation Reaction: Atom Efficient and Greener Syntheses of π-Conjugated Small Molecules and Macromolecules for Organic Electronic Materials
2013
Site-Selective Azaindole Arylation at the Azine and Azole Rings via N-Oxide Activation
2009
Metal Catalysts for Heterogeneous Catalysis: From Single Atoms to Nanoclusters and Nanoparticles
2018 Standout
Auxiliary-Enabled Pd-Catalyzed Direct Arylation of Methylene C(sp3)–H Bond of Cyclopropanes: Highly Diastereoselective Assembling of Di- and Trisubstituted Cyclopropanecarboxamides
2013
Palladium-Catalyzed Acylation of sp2 C−H bond: Direct Access to Ketones from Aldehydes
2009
Synthesis of Tricyclic Nitrogen Heterocycles by a Sequence of Palladium-Catalyzed N–H and C(sp3)–H Arylations
2011
Direct Synthesis of N-H Carbazoles via Iridium(III)-Catalyzed Intramolecular C–H Amination
2015
One-pot Sequential Direct C–H Bond Arylation of Azoles Catalyzed by [Pd(phen)2](PF6)2: Synthetic Methods for Triarylated Azoles
2012
Direct Synthesis of Pyrazolo[5,1‐a]isoindoles via Intramolecular Palladium‐Catalyzed CH Bond Activation
2010
Direct Arylation as a Synthetic Tool for the Synthesis of Thiophene-Based Organic Electronic Materials
2011
Modular Approach to Tricyclic Heterocycles through Copper Catalysis and Functionalization by Palladium‐Catalyzed C–H Arylation
2017
Catalytic iron-carbene intermediate revealed in a cytochrome c carbene transferase
2018 StandoutNobel
Copper-Catalyzed Oxidative Cross-Coupling ofN,N-Dimethylanilines with Heteroarenes under Molecular Oxygen
2011
Ynamides: A Modern Functional Group for the New Millennium
2010 Standout
Advances in Transition Metal (Pd,Ni,Fe)-Catalyzed Cross-Coupling Reactions Using Alkyl-organometallics as Reaction Partners
2011 Standout
Pd-catalyzed ortho-arylation of phenylacetamides, benzamides, and anilides with simple arenes using sodium persulfate
2010
Transition Metal-Catalyzed Direct Arylation of Substrates with Activated sp3-Hybridized C−H Bonds and Some of Their Synthetic Equivalents with Aryl Halides and Pseudohalides
2009
Covalent Organic Frameworks: Design, Synthesis, and Functions
2020 Standout
Homologation of the Fischer Indolization: A Quinoline Synthesis via Homo‐Diaza‐Cope Rearrangement
2020 StandoutNobel
Pd-Catalyzed Intramolecular Oxidative C–H Amination: Synthesis of Carbazoles
2011
Highly Site‐Selective and Direct Ortho‐C−H Nitration, Trifluoromethylation and Cyanation at the C1‐Position of Carbazole Frameworks
2016
Click chemistry with ynamides
2006
Undirected, Homogeneous C–H Bond Functionalization: Challenges and Opportunities
2016
Electroreductive intermolecular coupling of phthalimides with aldehydes: application to the synthesis of alkylideneisoindolin-1-ones
2012
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Synthesis of Biologically Active Carbazole Alkaloids Using Selective Transition-metal-catalyzed Coupling Reactions
2008
Silver-Promoted, Palladium-Catalyzed Direct Arylation of Cyclopropanes: Facile Access to Spiro 3,3′-Cyclopropyl Oxindoles
2013
Programmed Synthesis of Tetraarylthiophenes through Sequential C−H Arylation
2009
Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
2012 Standout
Versatile reactivity of Pd-catalysts: mechanistic features of the mono-N-protected amino acid ligand and cesium-halide base in Pd-catalyzed C–H bond functionalization
2014
Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope
2011 Standout
C–H Functionalization of Cyclopropanes: A Practical Approach Employing a Picolinamide Auxiliary
2013
Ni-Catalyzed Alkenylation of Triazolopyridines: Synthesis of 2,6-Disubstituted Pyridines
2012
Palladium-Catalyzed Transformations of Alkyl C–H Bonds
2016 Standout
Regioselective Palladium-Catalyzed Arylation of 4-Chloropyrazoles
2010
Carbonates: eco-friendly solvents for palladium-catalysed direct arylation of heteroaromatics
2010
Hydrofluoroarylation of Alkynes with Ni Catalysts. C–H Activation via Ligand-to-Ligand Hydrogen Transfer, an Alternative to Oxidative Addition
2011
Palladium-Catalyzed Direct Synthesis of Carbazoles via One-Pot N-Arylation and Oxidative Biaryl Coupling: Synthesis and Mechanistic Study
2009
Oxidative C–H/C–H Coupling Reactions between Two (Hetero)arenes
2017
N-Heterocyclic Carbenes in Late Transition Metal Catalysis
2009 Standout
Waste-Free Synthesis of Condensed Heterocyclic Compounds by Rhodium-Catalyzed Oxidative Coupling of Substituted Arene or Heteroarene Carboxylic Acids with Alkynes
2009
Total Synthesis of Dictyodendrins B and E, and Formal Synthesis of Dictyodendrin C
2014
Ring Construction by Palladium(0)-Catalyzed C(sp3)–H Activation
2017
Ruthenium-catalyzed [2+2] cycloadditions of bicyclic alkenes and ynamides
2006
The Complementary Competitors: Palladium and Copper in C–N Cross-Coupling Reactions
2012
Lithiation and functionalization of 1-alkynylimidazoles at the 2-position
2009
Oxalyl amide assisted palladium-catalyzed synthesis of pyrrolidones via carbonylation of γ-C(sp3)–H bonds of aliphatic amine substrates
2015
Domino Palladium-Catalyzed Heck-Intermolecular Direct Arylation Reactions
2009
Copper-catalyzed oxidative C(sp3)–H/C(sp2)–H cross-coupling en route to carbocyclic rings
2017
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
Mechanistic Insights into the Palladium‐Catalyzed Domino Synthesis of 10,11‐Dihydro‐5H‐dibenzo[b,e][1,4]diazepines
2014
Predictable and Site-Selective Functionalization of Poly(hetero)arene Compounds by Palladium Catalysis
2010
Complementary Strategies for Directed C(sp3)−H Functionalization: A Comparison of Transition‐Metal‐Catalyzed Activation, Hydrogen Atom Transfer, and Carbene/Nitrene Transfer
2017
Radical cascade cyclizations and platinum(II)-catalyzed cycloisomerizations of ynamides
2006
Palladium-Catalyzed Benzylation of Heterocyclic Aromatic Compounds
2009
Ruthenium(II) Acetate Catalyst for Direct Functionalisation of sp2‐CH Bonds with Aryl Chlorides and Access to Tris‐ Heterocyclic Molecules
2009
Investigation of the Mechanism of C(sp3)−H Bond Cleavage in Pd(0)-Catalyzed Intramolecular Alkane Arylation Adjacent to Amides and Sulfonamides
2010
Direct arylation of dithienylperfluorocyclopentenes via palladium-catalysed C–H bond activation: a simpler access to photoswitches
2012
Palladium-catalyzed regio- and chemoselective ortho-benzylation of C–H bond using a functionalizable primary amide directing group: a concise synthesis of dibenzo[b,e]azepin-6-ones
2013
Multifunctional and robust covalent organic framework–nanoparticle hybrids
2014
Azine Activation via Silylium Catalysis
2021 StandoutNobel
Evaluation of Electron‐Deficient Phosphine Ligands for Direct Arylation of Heterocycles
2010
Highly Regioselective Palladium-Catalyzed Direct Arylation of Oxazole at C-2 or C-5 with Aryl Bromides, Chlorides, and Triflates
2010
Enzymatic construction of highly strained carbocycles
2018 StandoutScienceNobel
Silver-Catalyzed Oxidative Coupling of Terminal Aromatic Alkynes and Benzylic Ethers
2010
Palladium‐Catalyzed C3 or C4 Direct Arylation of Heteroaromatic Compounds with Aryl Halides by CH Bond Activation
2009
Cu(II)-mediated oxidative dimerization of 2-phenylpyridine derivatives
2008
Synthesis of chiral allenes from ynamides through a highly stereoselective Saucy–Marbet rearrangement
2006
The broadening reach of frustrated Lewis pair chemistry
2016 StandoutScience
Enantioselective palladium(0)-catalyzed intramolecular cyclopropane functionalization: access to dihydroquinolones, dihydroisoquinolones and the BMS-791325 ring system
2015
Palladium-Catalyzed C−H Functionalization of Heteroarenes with Aryl Bromides and Chlorides
2010
Total Synthesis of Diptoindonesin G via a Highly Efficient Domino Cyclodehydration/Intramolecular Friedel−Crafts Acylation/Regioselective Demethylation Sequence
2010
Regioselective Ruthenium-Catalyzed Direct Benzylations of Arenes through C−H Bond Cleavages
2009
Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance
2017 Standout
Tandem azidination– and hydroazidination–Huisgen [3 + 2] cycloadditions of ynamides. Synthesis of chiral amide-substituted triazoles
2006
Synthesis of 5‐Alkyl[3,4‐c]thienopyrrole‐4,6‐dione‐Based Polymers by Direct Heteroarylation
2011
Total Synthesis of (±)-Rhazinal Using Novel Palladium-Catalyzed Cyclizations
2009
Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization
2012 Standout
Pd-Catalyzed Intermolecular ortho-C−H Amidation of Anilides by N-Nosyloxycarbamate
2010
Pd(II)-mediated cyclodehydrogenation of formyldiarylamines—total synthesis of natural carbazoles clauraila A, clausenal and 6-methoxymurrayanine
2015
A General Method for Copper-Catalyzed Arene Cross-Dimerization
2011
Regio- and Stereoselective Pd-Catalyzed Direct Arylation of Unactivated sp3 C(3)–H Bonds of Tetrahydrofuran and 1,4-Benzodioxane Systems
2015
Synthetic Development and Mechanistic Study on Pd(II)-Catalyzed Cyclization of Enediynes to Benzo[a]carbazoles
2010
Analysis of the Palladium-Catalyzed (Aromatic)C–H Bond Metalation–Deprotonation Mechanism Spanning the Entire Spectrum of Arenes
2011
Cu-Catalyzed Synthesis of Fluoroalkylated Isoxazoles from Commercially Available Amines and Alkynes
2018
A Highly Efficient Ruthenium(II) Catalyst with (1,2-Diarylvinyl)phosphine Ligands for Direct Ortho Arylation of 2-Arylpyridine with Aryl Chlorides
2010
Cross Dehydrogenative Arylation (CDA) of a Benzylic CH Bond with Arenes by Iron Catalysis
2009
Transition Metal-Catalyzed Decarboxylative Allylation and Benzylation Reactions
2011
“On Water” Direct and Site‐Selective Pd‐Catalysed CH Arylation of (NH)‐Indoles
2010
Palladium(II)-Catalyzed Oxidative C−H/C−H Cross-Coupling of Heteroarenes
2010
Palladium-catalyzed Direct C–H Bond Arylation of Simple Arenes with Aryltrimethylsilanes
2011
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
2020 StandoutNobel
Übergangsmetallkatalysierte direkte Arylierungen von (Hetero)Arenen durch C‐H‐Bindungsbruch
2009
Synthesis of Strained γ‐Lactams by Palladium(0)‐Catalyzed C(sp3)−H Alkenylation and Application to Alkaloid Synthesis
2016
Pd-Catalyzed π-Chelation Assisted ortho-C–H Activation and Annulation of Allylarenes with Internal Alkynes
2013
Copper Salt‐Catalyzed Azide‐[3 + 2] Cycloadditions of Ynamides and Bis‐Ynamides
2006
Completely Regioselective Direct C–H Functionalization of Benzo[b]thiophenes Using a Simple Heterogeneous Catalyst
2013
Gold-Catalyzed Deacylative Cycloisomerization Reactions of 3-Acylindole/ynes: A New Approach for Carbazole Synthesis
2011
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
A General Catalyst for the β‐Selective C–H Bond Arylation of Thiophenes with Iodoarenes
2010
The Nature of the Catalytically Active Species in Olefin Dioxygenation with PhI(OAc)2: Metal or Proton?
2011
Copper‐Catalyzed Cross‐Dehydrogenative Coupling (CDC) of Alkynes and Benzylic CH Bonds
2010
Coupling and cycloaddition of ynamides: homo- and Negishi coupling of tosylynamides and intramolecular [4+2] cycloaddition of N-(o-ethynyl)phenyl ynamides and arylynamides
2006
Functionalization of a Simple Dithienylethene via Palladium-Catalyzed Regioselective Direct Arylation
2011
C–H arylations of 1,2,3-triazoles by reusable heterogeneous palladium catalysts in biomass-derived γ-valerolactone
2016
Four Tandem C–H Activations: A Sequential C–C and C–O Bond Making via a Pd-Catalyzed Cross Dehydrogenative Coupling (CDC) Approach
2012
Double C−H Activation: The Palladium-Catalyzed Direct C-Arylation of Xanthines with Arenes
2011
Cu-mediated direct regioselective C-2 chlorination of indoles
2015
Intramolecular Oxidative C−N Bond Formation for the Synthesis of Carbazoles: Comparison of Reactivity between the Copper-Catalyzed and Metal-Free Conditions
2011
Palladium-Catalyzed Dehydrogenative Direct Arylations of 1,2,3-Triazoles
2010
Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis
2013 Standout
Nickel-Catalyzed Direct Thioetherification of β-C(sp3)–H Bonds of Aliphatic Amides
2015
Stereoselective Synthesis of Multisubstituted Enamides via Rhodium-Catalyzed Carbozincation of Ynamides
2009
Auxiliary-Assisted Palladium-Catalyzed Arylation and Alkylation of sp2 and sp3 Carbon−Hydrogen Bonds
2010
A short synthesis of lennoxamine via ynamides
2005
A New Synthetic Route to the 1-Oxygenated Carbazole Alkaloids, Mukonine and Clausine E (Clauzoline I)
2009
Overview of the Mechanistic Work on the Concerted Metallation–Deprotonation Pathway
2010 Standout
Transition Metal-Catalyzed C–H Amination: Scope, Mechanism, and Applications
2017 Standout
Synthesis of vinylpyrroles, vinylfurans and vinylindoles via a Brønsted acid catalyzed highly regio- and stereoselective cis-hydroarylation of ynamides
2006
Cobalt-Catalyzed Cross-Dehydrogenative Coupling Reaction between Unactivated C(sp2)–H and C(sp3)–H Bonds
2017
Direct C−H Transformation via Iron Catalysis
2010 Standout
Room-Temperature Direct Arylation of Polyfluorinated Arenes under Biphasic Conditions
2010
Acid‐Free Synthesis of Carbazoles and Carbazolequinones by Intramolecular Pd‐Catalyzed, Microwave‐Assisted Oxidative Biaryl Coupling Reactions – Efficient Syntheses of Murrayafoline A, 2‐Methoxy‐3‐methylcarbazole, and Glycozolidine
2009
Nickel-Catalyzed Oxidative Coupling of Unactivated C(sp3)–H Bonds in Aliphatic Amides with Terminal Alkynes
2016
Alternate Heme Ligation Steers Activity and Selectivity in Engineered Cytochrome P450-Catalyzed Carbene-Transfer Reactions
2018 StandoutNobel
A New Coumarin and Carbazole Alkaloid from Clausena vestita D. D. Tao
2010
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Enantioselective organocatalytic aldol reaction using small organic molecules
2012
Direct Arylations of 2H-Indazoles On Water
2009
β-Arylation of Carboxamides via Iron-Catalyzed C(sp3)–H Bond Activation
2013
Funktionalisierung von C‐H‐Bindungen: neue Synthesemethoden für Naturstoffe und Pharmazeutika
2012
Preparation of Multisubstituted Enamides via Rhodium-Catalyzed Carbozincation and Hydrozincation of Ynamides
2009
Ortho-C–H Benzylation of Aryl Imines with Benzyl Phosphates under Cobalt–Pyphos Catalysis
2015
Highly Efficient and Versatile Synthesis of Polyarylfluorenes via Pd-Catalyzed C−H Bond Activation
2009
Autocatalysis for C–H Bond Activation by Ruthenium(II) Complexes in Catalytic Arylation of Functional Arenes
2011
Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site
2023 StandoutNobel
Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions
2010 Standout
Irregularities in the Effect of Potassium Phosphate in Ynamide Synthesis
2008
TADDOL-based phosphorus(iii )-ligands in enantioselective Pd(0)-catalysed C–H functionalisations
2015
Palladium-Catalyzed Method for the Synthesis of Carbazoles via Tandem C−H Functionalization and C−N Bond Formation
2008
Synthesis of ynamides from formamides
2006
Mechanism of Benzoquinone-Promoted Palladium-Catalyzed Oxidative Cross-Coupling Reactions
2009
Oxindole Synthesis by Direct Coupling of CH and CH Centers
2009
Regioselective Oxidative Arylation of Indoles Bearing N-Alkyl Protecting Groups: Dual C−H Functionalization via a Concerted Metalation−Deprotonation Mechanism
2010
Synthesis of Pyrroles, Indoles, and Carbazoles through Transition‐Metal‐Catalyzed CH Functionalization
2013
Applications of C–H Functionalization Logic to Cyclobutane Synthesis
2014
Oxidative Pd(II)-Catalyzed C−H Bond Amination to Carbazole at Ambient Temperature
2008
Palladium-Catalyzed C−H Activation/C−N Bond Formation Reactions: DFT Study of Reaction Mechanisms and Reactive Intermediates
2010
CuI-Mediated Sequential Iodination/Cycloetherification ofo-Arylphenols: Synthesis of 2- or 4-Iododibenzofurans and Mechanistic Studies
2012
Synthesis of Functionalized Spiroindolines via Palladium-Catalyzed Methine C–H Arylation
2013
Challenge and progress: palladium-catalyzed sp3 C–H activation
2011
Syntheses of vinylindoles via a Brønsted acid catalyzed highly regio- and stereoselective cis-hydroarylation of ynamides
2005
Enantioselective Total Synthesis of Nigelladine A via Late-Stage C–H Oxidation Enabled by an Engineered P450 Enzyme
2017 StandoutNobel
Switching the Regioselectivity of Direct C–H Arylation of 1,3‐Dimethyluracil
2009
Works of Benoît Liégault being referenced
Activation and functionalization of benzylic derivatives by palladium catalysts
2007
Establishment of Broadly Applicable Reaction Conditions for the Palladium-Catalyzed Direct Arylation of Heteroatom-Containing Aromatic Compounds
2009
Modulating Reactivity and Diverting Selectivity in Palladium-Catalyzed Heteroaromatic Direct Arylation Through the Use of a Chloride Activating/Blocking Group
2010
Palladium(0)-catalyzed cyclopropane C–H bond functionalization: synthesis of quinoline and tetrahydroquinoline derivatives
2011
Heck−Suzuki−Miyaura Domino Reactions Involving Ynamides. An Efficient Access to 3-(Arylmethylene)isoindolinones
2004
Intramolecular Pd(II)-Catalyzed Oxidative Biaryl Synthesis Under Air: Reaction Development and Scope
2008
Synthesis of 3-(arylmethylene)isoindolin-1-ones from ynamides by Heck–Suzuki–Miyaura domino reactions. Application to the synthesis of lennoxamine
2006
Oxidative para-Triflation of Acetanilides
2013
Palladium-Catalyzed Intramolecular Coupling of Arenes and Unactivated Alkanes in Air
2008
Copper‐Catalyzed Insertion into Heteroatom–Hydrogen Bonds with Trifluorodiazoalkanes
2016
Diversity-Oriented Approach to CF3CHF-, CF3CFBr-, CF3CF2-, (CF3)2CH-, and CF3(SCF3)CH-Substituted Arenes from 1-(Diazo-2,2,2-trifluoroethyl)arenes
2014
(S,S,S)-Perhydroindolic acid: efficient catalyst for direct asymmetric aldol reaction from aromatic aldehydes
2006
Iodine(III)‐Mediated para‐Selective Direct Imidation of Anilides
2015