Citation Impact
Citing Papers
Generation of ordered protein assemblies using rigid three-body fusion
2021 StandoutNobel
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Rationally engineered Cas9 nucleases with improved specificity
2015 StandoutScience
Near-atomic cryo-EM imaging of a small protein displayed on a designed scaffolding system
2018
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN
2024 StandoutNobel
Progress and challenges towards targeted delivery of cancer therapeutics
2018 Standout
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy
2022 StandoutNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
2019 StandoutNobel
De novo design of immunoglobulin-like domains
2022 StandoutNobel
Controlling entropy to tune the functions of intrinsically disordered regions
2014
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
Key factors influencing ADME properties of therapeutic proteins: A need for ADME characterization in drug discovery and development
2015
Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity
2020 StandoutNobel
High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
2016 StandoutNature
PASylation: a biological alternative to PEGylation for extending the plasma half-life of pharmaceutically active proteins
2013
Cancer nanomedicine: progress, challenges and opportunities
2016 Standout
A chemical-inducible CRISPR–Cas9 system for rapid control of genome editing
2016
Expanding the Biologist’s Toolkit with CRISPR-Cas9
2015 StandoutNobel
X-ray scattering combined with coordinate-based analyses for applications in natural and artificial photosynthesis
2009
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
The journey of a drug-carrier in the body: An anatomo-physiological perspective
2011
Engineering interferons and interleukins for cancer immunotherapy
2022
Nanotechnology for protein delivery: Overview and perspectives
2015
Evolution of a designed protein assembly encapsulating its own RNA genome
2017 StandoutNatureNobel
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
2016 Standout
Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch
2016 StandoutNobel
Design of biologically active binary protein 2D materials
2021 StandoutNatureNobel
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
A Broad-Spectrum Inhibitor of CRISPR-Cas9
2017 StandoutNobel
The Acidic Transcription Activator Gcn4 Binds the Mediator Subunit Gal11/Med15 Using a Simple Protein Interface Forming a Fuzzy Complex
2011 StandoutNobel
Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification
2014
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Intrinsically disordered proteins in cellular signalling and regulation
2014 Standout
Genome engineering using the CRISPR-Cas9 system
2013 Standout
Fuzzy complexes: polymorphism and structural disorder in protein–protein interactions
2007
Human Carboxylesterase Isozymes: Catalytic Properties and Rational Drug Design
2006
A thermostable Cas9 with increased lifetime in human plasma
2017 StandoutNobel
Emerging Strategies for Developing Next-Generation Protein Therapeutics for Cancer Treatment
2016
Efficient generation of mouse models of human diseases via ABE- and BE-mediated base editing
2018 Standout
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
Human growth hormone expressed in tobacco cells as an arabinogalactan-protein fusion glycoprotein has a prolonged serum life
2010
Local and macroscopic electrostatic interactions in single α-helices
2015
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
Massively parallel kinetic profiling of natural and engineered CRISPR nucleases
2020 StandoutNobel
Electrostatic origin of the unidirectionality of walking myosin V motors
2013 StandoutNobel
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
Complexation of Polyoxometalates with Cyclodextrins
2015 StandoutNobel
The Current State of Peptide Drug Discovery: Back to the Future?
2017
Strategies for extended serum half-life of protein therapeutics
2011
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Self-Assembling 2D Arrays with de Novo Protein Building Blocks
2019 StandoutNobel
De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
2016 StandoutScienceNobel
Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
2016 StandoutScience
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
Design principles governing the motility of myosin V
2013
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Computational design of mechanically coupled axle-rotor protein assemblies
2022 StandoutScienceNobel
Networks of electrostatic and hydrophobic interactions modulate the complex folding free energy surface of a designed βα protein
2019 StandoutNobel
Engineering of temperature- and light-switchable Cas9 variants
2013 StandoutNobel
Protein Glycoengineering Enabled by the Versatile Synthesis of Aminooxy Glycans and the Genetically Encoded Aldehyde Tag
2011 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Works of Benjamin Spink being referenced
A Novel Long-Acting Human Growth Hormone Fusion Protein (VRS-317): Enhanced In Vivo Potency and Half-Life
2012
Gcg-XTEN: An Improved Glucagon Capable of Preventing Hypoglycemia without Increasing Baseline Blood Glucose
2010
Long single α-helical tail domains bridge the gap between structure and function of myosin VI
2008
A Flexible Domain Is Essential for the Large Step Size and Processivity of Myosin VI
2005
A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner
2009
Dynamic charge interactions create surprising rigidity in the ER/K α-helical protein motif
2008
Human liver carboxylesterase hCE-1: binding specificity for cocaine, heroin, and their metabolites and analogs.
1997