Citation Impact
Citing Papers
RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
2009 StandoutScience
TFEB Links Autophagy to Lysosomal Biogenesis
2011 StandoutScience
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production
2007 StandoutScience
Regulation of the gadd45β Promoter by NF-κB
2002
Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains
2009 Standout
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
2011 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
The role of hypoxia-inducible factors in tumorigenesis
2008
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
2004 Standout
Distinct Roles of the IκB Kinase α and β Subunits in Liberating Nuclear Factor κB (NF-κB) from IκB and in Phosphorylating the p65 Subunit of NF-κB
2002
Role of JNK1-dependent Bcl-2 Phosphorylation in Ceramide-induced Macroautophagy
2008
Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases
2005 Standout
JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species
2004
A JNK-Dependent Pathway Is Required for TNFα-Induced Apoptosis
2003
Inflammation and metabolic disorders
2006 StandoutNature
Activation of the JNK signaling pathway: Breaking the brake on apoptosis
2002
Differential Kinetic and Spatial Patterns of β-Arrestin and G Protein-mediated ERK Activation by the Angiotensin II Receptor
2004 StandoutNobel
Rb Regulates Interactions between Hematopoietic Stem Cells and Their Bone Marrow Microenvironment
2007
HIF-1: upstream and downstream of cancer metabolism
2009 StandoutNobel
Combinatorial Marking of Cells and Organelles with Reconstituted Fluorescent Proteins
2004 StandoutNobel
Essential role of RelA Ser311 phosphorylation by PKC in NF- B transcriptional activation
2003
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
IKKβ Couples Hepatocyte Death to Cytokine-Driven Compensatory Proliferation that Promotes Chemical Hepatocarcinogenesis
2005
Inhibition of NF-κB in cancer cells converts inflammation- induced tumor growth mediated by TNFα to TRAIL-mediated tumor regression
2004
Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L
2008
Liver Tumor Development
2003
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
Sin3: a flexible regulator of global gene expression and genome stability
2004
AP-1 as a regulator of cell life and death
2002 Standout
NF- B inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death
2003
NF-κB activation by reactive oxygen species: Fifteen years later
2006
The Signaling Adaptor p62 Is an Important NF-κB Mediator in Tumorigenesis
2008
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Autophagy: Renovation of Cells and Tissues
2011 Standout
IKKβ Is Required for Prevention of Apoptosis Mediated by Cell-Bound but Not by Circulating TNFα
2003
To be, or not to be: NF-κB is the answer – role of Rel/NF-κB in the regulation of apoptosis
2003
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Hypoxia-selective macroautophagy and cell survival signaled by autocrine PDGFR activity
2009
Regulation of Mitochondrial Integrity, Autophagy and Cell Survival by BNIP3
2007
IKK/NF- B signaling: balancing life and death - a new approach to cancer therapy
2005 Standout
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
2007 StandoutNature
FoxO3 Controls Autophagy in Skeletal Muscle In Vivo
2007 Standout
Transient activation of NF-κB through a TAK1/IKK kinase pathway by TGF-β1 inhibits AP-1/SMAD signaling and apoptosis: implications in liver tumor formation
2003
Novel Roles for Protein Kinase C;-dependent Signaling Pathways in Acute Hypoxic Stress-induced Autophagy
2008
Immunity, Inflammation, and Cancer
2010 Standout
IEX-1: a new ERK substrate involved in both ERK survival activity and ERK activation
2002
IAP proteins: blocking the road to death's door
2002
Cellular mechanisms of tumour suppression by the retinoblastoma gene
2008
NF-κB in cancer: a marked target
2003
The signaling adaptors and pathways activated by TNF superfamily
2003
Tumor necrosis factor signaling
2003 Standout
Anti-Vascular Endothelial Growth Factors Protect Retinal Pigment Epithelium Cells Against Oxidation by Modulating Nitric Oxide Release and Autophagy
2017 Standout
Targeting of TAK1 by the NF-κB protein Relish regulates the JNK-mediated immune response in Drosophila
2004
Role of BNIP3 and NIX in cell death, autophagy, and mitophagy
2009
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
NF-κB Is Required for UV-Induced JNK Activation via Induction of PKCδ
2006
Visualization of Interactions among bZIP and Rel Family Proteins in Living Cells Using Bimolecular Fluorescence Complementation
2002
Tumor Necrosis Factor-induced Nonapoptotic Cell Death Requires Receptor-interacting Protein-mediated Cellular Reactive Oxygen Species Accumulation
2004
Signaling to NF-κB
2004 Standout
The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNFα-induced Cell Death by Inducing c-FLIPL Turnover
2006
JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species
2005
Lipid raft: A floating island of death or survival
2012
NF-κB functions as a tumour promoter in inflammation-associated cancer
2004 StandoutNature
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Ferritin Heavy Chain Upregulation by NF-κB Inhibits TNFα-Induced Apoptosis by Suppressing Reactive Oxygen Species
2004
MyD88S, a splice variant of MyD88, differentially modulates NF‐κB‐ and AP‐1‐dependent gene expression
2003
Cancer-related inflammation
2008 StandoutNature
NF-κB at the crossroads of life and death
2002 Standout
NF-κB RelA opposes epidermal proliferation driven by TNFR1 and JNK
2004
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Autophagy: cellular and molecular mechanisms
2010 Standout
Oxygen homeostasis
2009 StandoutNobel
The cancer genome
2009 StandoutNature
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase
2018 StandoutNobel
Role of SODD in Regulation of Tumor Necrosis Factor Responses
2003
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
2006 StandoutScience
Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
2011 Standout
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Role of glycogen synthase kinase-3 in TNF-α-induced NF-κB activation and apoptosis in hepatocytes
2002
Oncogenic transformation and experimental models of human cancer
2007
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
2006 StandoutNobel
Regulation Mechanisms and Signaling Pathways of Autophagy
2009 Standout
Fast structural responses of gap junction membrane domains to AB5 toxins
2013 StandoutNobel
Inhibitor of nuclear factor kappaB kinase deficiency enhances oxidative stress and prolongs c-Jun NH2-terminal kinase activation induced by arsenic.
2003
JunD Mediates Survival Signaling by the JNK Signal Transduction Pathway
2003
Spermidine in health and disease
2018 StandoutScience
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Linking JNK signaling to NF-κB: a key to survival
2004
Hypoxia‐induced BNIP3 expression and mitophagy: in vivo comparison of the rat and the hypoxia‐tolerant mole rat, Spalax ehrenbergi
2009
Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis
2006 StandoutNobel
Loss of hepatic NF-κB activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation
2006
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Autophagy and Metabolism
2010 StandoutScience
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
Reactive Oxygen Species (ROS), Troublemakers between Nuclear Factor-κB (NF-κB) and c-Jun NH2-terminal Kinase (JNK)
2004
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
2012 StandoutNobel
NIX is required for programmed mitochondrial clearance during reticulocyte maturation
2007
The Double-Edged Sword of Autophagy Modulation in Cancer
2009
NF-κB in cancer—a friend turned foe
2004
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Works of Benjamin Dibling being referenced
New roles for the RB tumor suppressor protein
2003
The true face of JNK activation in apoptosis
2002
The Rb tumor suppressor is required for stress erythropoiesis
2004
Inhibition of JNK activation through NF-κB target genes
2001 Nature
BNIP3 Is an RB/E2F Target Gene Required for Hypoxia-Induced Autophagy
2007