Citation Impact
Citing Papers
A Cluster of Metabolic Defects Caused by Mutation in a Mitochondrial tRNA
2004 Science
Alpelisib for PIK3CA -Mutated, Hormone Receptor–Positive Advanced Breast Cancer
2019 Standout
Pathophysiology of Migraine: A Disorder of Sensory Processing
2017 Standout
TOR Signaling in Growth and Metabolism
2006 Standout
Benefits and limitations of genome-wide association studies
2019
Unraveling the brain regulation of appetite: lessons from genetics
2012
Signals from the lysosome: a control centre for cellular clearance and energy metabolism
2013 Standout
Molecular Architecture of the Mouse Nervous System
2018 Standout
Identification and Importance of Brown Adipose Tissue in Adult Humans
2009 Standout
Constitutive Activity in Melanocortin-4 Receptor
2014
Role of central melanocortin pathways in energy homeostasis
2009
Anatomy and regulation of the central melanocortin system
2005 Standout
Computational disease gene identification: a concert of methods prioritizes type 2 diabetes and obesity candidate genes
2006
Mitochondria: Dynamic Organelles in Disease, Aging, and Development
2006 Standout
MC4R Agonists: Structural Overview on Antiobesity Therapeutics
2018 StandoutNobel
Central nervous system control of food intake and body weight
2006 StandoutNature
Post-transcriptional gene regulation by mRNA modifications
2016 Standout
Heterogeneity of hypothalamic pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencing
2017
Peptide YY3–36Inhibits Food Intake in Mice through a Melanocortin-4 Receptor-Independent Mechanism
2004
Childhood obesity: public-health crisis, common sense cure
2002 Standout
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
2008 Standout
Cushing's syndrome
2015 Standout
The Human Intestinal Microbiome in Health and Disease
2016 Standout
Uncoupling protein 1 and 3 polymorphisms are associated with waist-to-hip ratio
2003
Treatment of Obesity with Celastrol
2015 Standout
Gut Commensal E. coli Proteins Activate Host Satiety Pathways following Nutrient-Induced Bacterial Growth
2015
Discovery of Novel AKT Inhibitors with Enhanced Anti-Tumor Effects in Combination with the MEK Inhibitor
2014
The bigger picture of FTO—the first GWAS-identified obesity gene
2013
Inactivation of Signal Transducer and Activator of Transcription 3 in Proopiomelanocortin (Pomc) Neurons Causes Decreased Pomc Expression, Mild Obesity, and Defects in Compensatory Refeeding
2006
Amino acids and mTORC1: from lysosomes to disease
2012
Maternal and child undernutrition and overweight in low-income and middle-income countries
2013 Standout
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
2009 Standout
mTOR at the nexus of nutrition, growth, ageing and disease
2020 Standout
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
2007 StandoutNature
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
Proopiomelanocortin Neurons in Nucleus Tractus Solitarius Are Activated by Visceral Afferents: Regulation by Cholecystokinin and Opioids
2005
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Autism-Associated Neuroligin-3 Mutations Commonly Disrupt Tonic Endocannabinoid Signaling
2013 StandoutNobel
SHORT Syndrome with Partial Lipodystrophy Due to Impaired Phosphatidylinositol 3 Kinase Signaling
2013
Enhanced Leptin-Stimulated Pi3k Activation in the CNS Promotes White Adipose Tissue Transdifferentiation
2007 StandoutNobel
A Partial Loss-of-Function Variant in AKT2 Is Associated With Reduced Insulin-Mediated Glucose Uptake in Multiple Insulin-Sensitive Tissues: A Genotype-Based Callback Positron Emission Tomography Study
2017
Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms
2004 Standout
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
Biology of Incretins: GLP-1 and GIP
2007 Standout
Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association
2021 Standout
PI3K integrates the action of insulin and leptin on hypothalamic neurons
2005
Peripheral administration of PYY3–36 produces conditioned taste aversion in mice
2005
Initial sequence of the chimpanzee genome and comparison with the human genome
2005 StandoutNature
Short Neuropeptide F Is a Sleep-Promoting Inhibitory Modulator
2013 StandoutNobel
The role of proopiomelanocortin (POMC) neurones in feeding behaviour
2007
Targeting AKT1-E17K and the PI3K/AKT Pathway with an Allosteric AKT Inhibitor, ARQ 092
2015
Mechanisms linking obesity to insulin resistance and type 2 diabetes
2006 StandoutNature
Leptin Receptor Signaling in POMC Neurons Is Required for Normal Body Weight Homeostasis
2004
Differential Regulation of Synaptic Inputs by Constitutively Released Endocannabinoids and Exogenous Cannabinoids
2005
Modern science versus the stigma of obesity
2004
Lynch syndrome and urologic malignancies
2019
Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans
2004
Genetic determinants of common obesity and their value in prediction
2012
Leptin at 14 y of age: an ongoing story
2009
Identification of Akt-independent Regulation of Hepatic Lipogenesis by Mammalian Target of Rapamycin (mTOR) Complex 2
2012
NPY receptors as potential targets for anti‐obesity drug development
2011
The Human Obesity Gene Map: The 2001 Update
2002
Childhood obesity
2010
The Human Obesity Gene Map: The 2003 Update
2004
AKT/PKB Signaling: Navigating the Network
2017 Standout
Proopiomelanocortin, a polypeptide precursor with multiple functions: from physiology to pathological conditions
2003
Dysregulation of insulin receptor substrate 2 in β cells and brain causes obesity and diabetes
2004
Cushing's syndrome
2006 Standout
The PI3K Pathway in Human Disease
2017 Standout
The regulation of food intake by selective stimulation of the type 3 melanocortin receptor (MC3R)
2005
Somatic Mosaic Activating Mutations in PIK3CA Cause CLOVES Syndrome
2012
Melanocortin-4 receptor–regulated energy homeostasis
2016
The molecular neurobiology of depression
2008 StandoutNature
Somatic Activation of AKT3 Causes Hemispheric Developmental Brain Malformations
2012
Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6
2008 Standout
The role of gut hormones in the regulation of body weight and energy homeostasis
2009
Body weight is regulated by the brain: a link between feeding and emotion
2005
Effects of Hypothalamic Neurodegeneration on Energy Balance
2005
The Human Obesity Gene Map: The 2004 Update
2005
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist
2016
ToppGene Suite for gene list enrichment analysis and candidate gene prioritization
2009 Standout
The Role of the Thyrotropin-Releasing Hormone (TRH) Neuron as a Metabolic Sensor
2008
Pathophysiology of Human Visceral Obesity: An Update
2013 Standout
Can Gut Hormones Control Appetite and Prevent Obesity?
2008
Regulation of Thyrotropin-Releasing Hormone-Expressing Neurons in Paraventricular Nucleus of the Hypothalamus by Signals of Adiposity
2010
Gut Microbiota in Health and Disease
2010 Standout
Obesity and Cardiovascular Disease: Pathophysiology, Evaluation, and Effect of Weight Loss
2005 Standout
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Type 2 diabetes: principles of pathogenesis and therapy
2005 Standout
Genetic Factors in Type 2 Diabetes: The End of the Beginning?
2005 Science
Postembryonic ablation of AgRP neurons in mice leads to a lean, hypophagic phenotype
2005
Minireview: CNS Mechanisms of Leptin Action
2015
Bladder Cancer
2020 Standout
Genetics of obesity
2006
Minireview: The Adipocyte—At the Crossroads of Energy Homeostasis, Inflammation, and Atherosclerosis
2003
How Obesity Causes Diabetes: Not a Tall Tale
2005 Science
Brown Adipose Tissue: Function and Physiological Significance
2004 Standout
Peripheral Exendin-4 and Peptide YY3–36 Synergistically Reduce Food Intake through Different Mechanisms in Mice
2005
Thyroid Hormone Regulation of Metabolism
2014 Standout
Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans
2004
Mitochondrial Dysfunction and Type 2 Diabetes
2005 StandoutScience
Metabolic reprogramming and cancer progression
2020 StandoutScience
Maintenance of the thyroid axis during diet-induced obesity in rodents is controlled at the central level
2010
The gut microbiota as an environmental factor that regulates fat storage
2004 Standout
The Melanocortin-4 Receptor: Physiology, Pharmacology, and Pathophysiology
2010
Essential Role of Pten in Body Size Determination and Pancreatic β-Cell Homeostasis In Vivo
2006 StandoutNobel
A role for arcuate cocaine and amphetamine regulated transcript in hyperphagia, thermogenesis, and cold adaptation
2003
Phosphatidylinositol 3-Kinase, Growth Disorders, and Cancer
2018
Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice
2010
Works of Benjamin Challis being referenced
An Activating Mutation of AKT2 and Human Hypoglycemia
2011 Science
Genetic variation in the corticotrophin-releasing factor receptors: identification of single-nucleotide polymorphisms and association studies with obesity in UK Caucasians
2004
Familial Adrenocortical Carcinoma in Association With Lynch Syndrome
2016
Acute effects of PYY3–36 on food intake and hypothalamic neuropeptide expression in the mouse
2003
Orexin Expression is Regulated by α‐Melanocyte‐Stimulating Hormone
2007
A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism
2002
Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY 3-36
2004
Proopiomelanocortin and Energy Balance: Insights from Human and Murine Genetics
2004
Minireview: Human Obesity—Lessons from Monogenic Disorders
2003
Association of Polymorphisms in GPR10, the Gene Encoding the Prolactin-Releasing Peptide Receptor With Blood Pressure, but not Obesity, in a U.K. Caucasian Population
2003
Loss of Agouti-Related Peptide Does Not Significantly Impact the Phenotype of Murine POMC Deficiency
2011
Association Between Physical Activity and Blood Pressure Is Modified by Variants in the G-Protein Coupled Receptor 10
2003
The CART gene and human obesity: mutational analysis and population genetics.
2000
Proopiomelanocortin-Deficient Mice Are Hypersensitive to the Adverse Metabolic Effects of Glucocorticoids
2005
Heterozygosity for a POMC-Null Mutation and Increased Obesity Risk in Humans
2006