Citation Impact
Citing Papers
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
Neuropharmacology of AMPA and kainate receptors
1998
Kainate receptors: Pharmacology, function and therapeutic potential
2008
Ligands for Glutamate Receptors: Design and Therapeutic Prospects
2000
Hypoxia-inducible factors enhance glutamate signaling in cancer cells
2014 StandoutNobel
Ionotropic and metabotropic glutamate receptor structure and pharmacology
2005
Kainate receptor pharmacology and physiology
1999
Pharmacological characterization of a GluR6 kainate receptor in cultured hippocampal neurons
1999
Pharmacology of AMPA/Kainate Receptor Ligands and Their Therapeutic Potential in Neurological and Psychiatric Disorders
2000
Selective agonist binding of (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) and 2S-(2α,3β,4β)-2-carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid (kainate) receptors: a molecular modeling study
2003
Glutamate receptor ion channels
2005 Standout
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
2010 Standout
The hERG potassium channel and hERG screening for drug-induced torsades de pointes
2008
A human ether-á-go-go-related (hERG) ion channel atomistic model generated by long supercomputer molecular dynamics simulations and its use in predicting drug cardiotoxicity
2014 StandoutNobel
The influence of drug-like concepts on decision-making in medicinal chemistry
2007 Standout
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Descending control of pain
2002 Standout
Traumatic Spinal Cord Injury: An Overview of Pathophysiology, Models and Acute Injury Mechanisms
2019 Standout
Glutamate uptake
2001 Standout
Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II with Reduced pKa: Antibacterial Agents with an Improved Safety Profile
2012
Investigation of miscellaneous hERG inhibition in large diverse compound collection using automated patch-clamp assay
2016
Pharmacological characterization of glutamatergic agonists and antagonists at recombinant human homomeric and heteromeric kainate receptors in vitro
2004
Computational Methods in Drug Discovery
2014
A structure-based computational workflow to predict liability and binding modes of small molecules to hERG
2020 StandoutNobel
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
A quantitative assessment of hERG liability as a function of lipophilicity
2006
A review on continuous-flow microfluidic PCR in droplets: Advances, challenges and future
2016
Novel 2-(2,4-dioxo-1,3-thiazolidin-5-yl)acetamides as antioxidant and/or anti-inflammatory compounds
2013
In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes
2009 StandoutNobel
Development and Comparison of hERG Blocker Classifiers: Assessment on Different Datasets Yields Markedly Different Results
2011
Identification of Subunit- and Antagonist-Specific Amino Acid Residues in the N-Methyl-d-aspartate Receptor Glutamate-Binding Pocket
2005
Heart repair by reprogramming non-myocytes with cardiac transcription factors
2012 Nature
An introduction to QT interval prolongation and non‐clinical approaches to assessing and reducing risk
2010
Indoles as therapeutics of interest in medicinal chemistry: Bird's eye view
2017 Standout
Kainate receptors
2006
Diverse array-designed modes of combination therapies in Fangjiomics
2015
Assessing the proarrhythmic potential of drugs: Current status of models and surrogate parameters of torsades de pointes arrhythmias
2006
Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes
2017 StandoutNobel
Reducing safety-related drug attrition: the use of in vitro pharmacological profiling
2012
Activity-dependent regulation of dendritic synthesis and trafficking of AMPA receptors
2004 StandoutNobel
NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease
2013 Standout
An analysis of the attrition of drug candidates from four major pharmaceutical companies
2015 Standout
A comprehensive review in current developments of benzothiazole-based molecules in medicinal chemistry
2014 Standout
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed
2012 Standout
Engineering Adolescence
2014 Standout
Applications of the Morris water maze in the study of learning and memory
2001 Standout
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
In Silico Binary Classification QSAR Models Based on 4D-Fingerprints and MOE Descriptors for Prediction of hERG Blockage
2010
The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
2011 Standout
Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II: Broad-Spectrum Antibacterial Agents with Reduced hERG Activity
2011
admetSAR: A Comprehensive Source and Free Tool for Assessment of Chemical ADMET Properties
2012 Standout
Molecular Docking and Structure-Based Drug Design Strategies
2015 Standout
Antimicrobial Resistance in Neisseria gonorrhoeae in the 21st Century: Past, Evolution, and Future
2014 Standout
Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
2011 StandoutNobel
Pharmacological and electrophysiological characterization of nine, single nucleotide polymorphisms of the hERG‐encoded potassium channel
2009
Molecular Docking: Shifting Paradigms in Drug Discovery
2019 Standout
Non-quinolone Inhibitors of Bacterial Type IIA Topoisomerases: A Feat of Bioisosterism
2013
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
ETCM: an encyclopaedia of traditional Chinese medicine
2018 Standout
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Oxadiazole isomers: all bioisosteres are not created equal
2012
Applications of Fluorine in Medicinal Chemistry
2015 Standout
Emerging Droplet Microfluidics
2017 Standout
Discovery of 4-{4-[(3R)-3-Methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1H-indole (AZ20): A Potent and Selective Inhibitor of ATR Protein Kinase with Monotherapy in Vivo Antitumor Activity
2013
Works of Ben G. Small being referenced
Efficient discovery of anti-inflammatory small-molecule combinations using evolutionary computing
2011
LY339434, a GluR5 kainate receptor agonist
1998
Evidence for gender differences in electrophysiological properties of canine Purkinje fibres
2004
Validation of a voltage-sensitive dye (di-4-ANEPPS)-based method for assessing drug-induced delayed repolarisation in Beagle dog left ventricular midmyocardial myocytes
2009
Optimisation and validation of a medium-throughput electrophysiology-based hERG assay using IonWorks™ HT
2006
Optimisation and validation of a medium-throughput electrophysiology-based hNav1.5 assay using IonWorks™
2007