Citation Impact
Citing Papers
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Efficient and Chemoselective Reduction of Pyridines to Tetrahydropyridines and Piperidines via Rhodium‐Catalyzed Transfer Hydrogenation
2012
The Cambridge Structural Database
2016 Standout
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Platensimycin and platencin: promising antibiotics for future application in human medicine
2011
Discovery of novel FabF ligands inspired by platensimycin by integrating structure-based design with diversity-oriented synthetic accessibility
2013
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
The use of platensimycin and platencin to fight antibiotic resistance
2013
Glucagon-Like Peptide-1 and Its Class B G Protein–Coupled Receptors: A Long March to Therapeutic Successes
2016
In vivo veritas, the next frontier for functionally selective GPCR ligands
2015
Psychedelic-inspired drug discovery using an engineered biosensor
2021
Accurate structure prediction of peptide–MHC complexes for identifying highly immunogenic antigens
2013
Organocatalytic cascade reactions as a new tool in total synthesis
2010 Standout
Natural products: A continuing source of novel drug leads
2013 Standout
Multi-input chemical control of protein dimerization for programming graded cellular responses
2019 StandoutNobel
PLIP: fully automated protein–ligand interaction profiler
2015 Standout
Polypharmacology of dopamine receptor ligands
2016
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
ASD v3.0: unraveling allosteric regulation with structural mechanisms and biological networks
2015
Sila‐Haloperidol, a Silicon Analogue of the Dopamine (D 2 ) Receptor Antagonist Haloperidol: Synthesis, Pharmacological Properties, and Metabolic Fate
2007
Clinical approaches to treatment of Internet addiction
2014 Standout
How Ligands Illuminate GPCR Molecular Pharmacology
2017
Molecular Dynamics Simulation for All
2018 Standout
Modeling the human Na<sub>v</sub>1.5 sodium channel: structural and mechanistic insights of ion permeation and drug blockade
2017 StandoutNobel
Challenges and advances in computational docking: 2009 in review
2010
Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments
2013 Standout
Modelling and enhanced molecular dynamics to steer structure-based drug discovery
2013
Synthesis and biological investigation of potential atypical antipsychotics with a tropane core. Part 1
2011
Structure-based drug screening for G-protein-coupled receptors
2012 StandoutNobel
Recent updates on GPCR biased agonism
2016
Protecting-group-free synthesis as an opportunity for invention
2009
EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics
2017
The neural basis of psychedelic action
2022 Standout
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
Synthetic approaches to the 2013 new drugs
2015
The Use of GPCR Structures in Drug Design
2011
A Pluridimensional View of Biased Agonism
2016
Skepinone-L, a Novel Potent and Highly Selective Inhibitor of p38 MAP Kinase, Effectively Impairs Platelet Activation and Thrombus Formation
2013 Standout
Structural Prediction of Peptide–MHC Binding Modes
2022
Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication
2018 Standout
Reassessment of Exosome Composition
2019 Standout
Synthesis and direct assay of large macrocycle diversities by combinatorial late-stage modification at picomole scale
2022
The Golden Age of Transfer Hydrogenation
2015 Standout
Structurally Enabled Discovery of Adenosine A2A Receptor Antagonists
2016
Platensimycin and Platencin Congeners from Streptomyces platensis
2011
Biased ligand quantification in drug discovery: from theory to high throughput screening to identify new biased μ opioid receptor agonists
2016
Covalent Organic Frameworks for Carbon Dioxide Capture from Air
2022 StandoutNobel
Highly soluble olanzapinium maleate crystalline salts
2011
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Ruthenium-Catalyzed ortho-C–H Mono- and Di-imidation of Arenes with N-Tosyloxyphthalimide
2015
Sulfonyl Fluorides (SFs): More Than Click Reagents?
2018
Antibiotics and Bacterial Resistance in the 21st Century
2014 Standout
The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
2011 Standout
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
Reticulating 1D Ribbons into 2D Covalent Organic Frameworks by Imine and Imide Linkages
2020 StandoutNobel
Multistep Solid-State Organic Synthesis of Carbamate-Linked Covalent Organic Frameworks
2019 StandoutNobel
Discovery of Imidazo[1,5-a]pyrido[3,2-e]pyrazines as a New Class of Phosphodiesterase 10A Inhibitiors
2010
Allostery and Biased Agonism at Class B G Protein-Coupled Receptors
2016
Covalent Organic Frameworks: Design, Synthesis, and Functions
2020 Standout
Emerging Cytotoxic Alkaloids in the Battle against Cancer: Overview of Molecular Mechanisms
2017
Molecular Docking and Structure-Based Drug Design Strategies
2015 Standout
Directory of Useful Decoys, Enhanced (DUD-E): Better Ligands and Decoys for Better Benchmarking
2012 Standout
Peptide-binding specificity prediction using fine-tuned protein structure prediction networks
2023 StandoutNobel
Teaching Three-Dimensional Structural Chemistry Using Crystal Structure Databases. 4. Examples of Discovery-Based Learning Using the Complete Cambridge Structural Database
2011
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
2020 StandoutNobel
Psychedelic-Inspired Drug Discovery Using an Engineered Biosensor
2020
Structure-inspired design of β-arrestin-biased ligands for aminergic GPCRs
2017
Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?
2015 Standout
Digital Reticular Chemistry
2020 StandoutNobel
A Refined Model of the HCV NS5A Protein Bound to Daclatasvir Explains Drug-Resistant Mutations and Activity against Divergent Genotypes
2014 StandoutNobel
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Solubility Advantage of Amorphous Drugs and Pharmaceutical Cocrystals
2011 Standout
Molecular Docking: Challenges, Advances and its Use in Drug Discovery Perspective
2018 Standout
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
2020 StandoutNobel
Ligand and Decoy Sets for Docking to G Protein-Coupled Receptors
2011
Aromatic Trifluoromethylation with Metal Complexes
2011 Standout
Plant Secondary Metabolites as Anticancer Agents: Successes in Clinical Trials and Therapeutic Application
2018 Standout
Natural Products as Sources of New Drugs from 1981 to 2014
2016 Standout
Latest developments in molecular docking: 2010–2011 in review
2013
Update 1 of: Computational Modeling Approaches to Structure–Function Analysis of G Protein-Coupled Receptors
2011
Transition Metal-Catalyzed C–H Amination: Scope, Mechanism, and Applications
2017 Standout
Current Assessment of Docking into GPCR Crystal Structures and Homology Models: Successes, Challenges, and Guidelines
2012
Ester-Linked Crystalline Covalent Organic Frameworks
2020 StandoutNobel
Life Beyond Kinases: Structure-Based Discovery of Sorafenib as Nanomolar Antagonist of 5-HT Receptors
2012
Hydrazine-Hydrazide-Linked Covalent Organic Frameworks for Water Harvesting
2022 StandoutNobel
Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design
2011 Standout
Works of Ben Capuano being referenced
Structure–Activity Relationships of Privileged Structures Lead to the Discovery of Novel Biased Ligands at the Dopamine D 2 Receptor
2014
The design, synthesis and biological evaluation of novel URB602 analogues as potential monoacylglycerol lipase inhibitors
2011
A new mechanism of allostery in a G protein–coupled receptor dimer
2014
Synthesis and SAR study of 4-arylpiperidines and 4-aryl-1,2,3,6-tetrahydropyridines as 5-HT2C agonists
2012
Synthesis and Pharmacological Evaluation of Dual Acting Ligands Targeting the Adenosine A2A and Dopamine D2 Receptors for the Potential Treatment of Parkinson’s Disease
2014
Schizophrenia: Genesis, Receptorology and Current Therapeutics
2002
The role of kinetic context in apparent biased agonism at GPCRs
2016
Novel adenosine A2A receptor ligands: A synthetic, functional and computational investigation of selected literature adenosine A2A receptor antagonists for extending into extracellular space
2013
The Dopamine D<sub>2</sub> and Adenosine A<sub>2A</sub> Receptors: Past, Present and Future Trends for the Treatment of Parkinson’s Disease
2014
Platensimycin: A Promising Antimicrobial Targeting Fatty Acid Synthesis
2008
Homology Modeling and Docking Evaluation of Aminergic G Protein-Coupled Receptors
2010
Simplified platensimycin analogues as antibacterial agents
2011
Proof of Concept Study for Designed Multiple Ligands Targeting the Dopamine D2, Serotonin 5-HT2A, and Muscarinic M1Acetylcholine Receptors
2015
Biased Agonism at G Protein‐Coupled Receptors: The Promise and the Challenges—A Medicinal Chemistry Perspective
2014
Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiLX)
2020
Synthesis and Pharmacological Evaluation of Analogues of Benzyl Quinolone Carboxylic Acid (BQCA) Designed to Bind Irreversibly to an Allosteric Site of the M1Muscarinic Acetylcholine Receptor
2014
Conformational Analysis of Drug Molecules: A Practical Exercise in the Medicinal Chemistry Course
2009
Progress Toward the Development of Noscapine and Derivatives as Anticancer Agents
2015
2-Methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine methanol solvate monohydrate
2003
The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells
2017
A Structure–Activity Analysis of Biased Agonism at the Dopamine D2 Receptor
2013