Citation Impact
Citing Papers
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking
2007 StandoutNobel
Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences
2006 Standout
Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution
2009 StandoutScienceNobel
STAR: ultrafast universal RNA-seq aligner
2012 Standout
Structural Roles for Human Translation Factor eIF3 in Initiation of Protein Synthesis
2005 StandoutScienceNobel
Mechanical Devices of the Spliceosome: Motors, Clocks, Springs, and Things
1998
RNA polymerase II and the integration of nuclear events
2000
Distinct requirements for C.elegans TAFIIs in early embryonic transcription
2001
Messenger RNAs are recruited for nuclear export during transcription
2001
The DEAD-box protein Ded1 unwinds RNA duplexes by a mode distinct from translocating helicases
2006
Essential role of mouse telomerase in highly proliferative organs
1998 StandoutNatureNobel
Crystal Structure of Prp5p Reveals Interdomain Interactions that Impact Spliceosome Assembly
2013
Pre-mRNA splicing in the new millennium
2001
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
Yeast Pre-mRNA splicing: Methods, mechanisms, and machinery
2002
Telomeres: No end in sight
1994 StandoutNobel
Discriminatory RNP remodeling by the DEAD-box protein DED1
2006
Comparative Structural Analysis of Human DEAD-Box RNA Helicases
2010
RNA-RNA interactions in the spliceosome: Unraveling the ties that bind
1994
Binding of Nucleotides by T4 DNA Ligase and T4 RNA Ligase: Optical Absorbance and Fluorescence Studies
2001
Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis
2007 StandoutNobel
Structure-Function Analysis of T4 RNA Ligase 2
2003
Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3
2015 StandoutNobel
SSL2, a suppressor of a stem-loop mutation in the HIS4 leader encodes the yeast homolog of human ERCC-3
1992
A Common Core RNP Structure Shared between the Small Nucleoar Box C/D RNPs and the Spliceosomal U4 snRNP
2000 StandoutNobel
Translation Initiation on Mammalian mRNAs with Structured 5′UTRs Requires DExH-Box Protein DHX29
2008
The CRISPR-associated Csx1 protein of Pyrococcus furiosus is an adenosine-specific endoribonuclease
2015
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
The Spliceosome: Design Principles of a Dynamic RNP Machine
2009 Standout
Early Formation of mRNP
2003 StandoutNobel
RSC, an Essential, Abundant Chromatin-Remodeling Complex
1996 StandoutNobel
An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs
1987 Standout
The Long Unwinding Road of RNA Helicases
2007
DExD/H Box RNA Helicases
2001
Unwinding dosage compensation
1993
Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit
2013 StandoutNatureNobel
An extensive network of coupling among gene expression machines
2002 Nature
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
Exchange of RNA Polymerase II Initiation and Elongation Factors during Gene Expression In Vivo
2002
Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast
1994 StandoutNatureNobel
Viral and cellular mRNA capping: Past and prospects
2000
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
1993 StandoutNobel
Remodeling of ribonucleoprotein complexes with DExH/D RNA helicases
2006
Structure, mechanism, and evolution of the mRNA capping apparatus
2000
Biochemical Mechanisms of Constitutive and Regulated Pre-mRNA Splicing
1991
An RNA Switch at the 5′ Splice Site Requires ATP and the DEAD Box Protein Prp28p
1999
A nuclear pore complex protein that contains zinc finger motifs, binds DNA, and faces the nucleoplasm
1993 StandoutNobel
Crystal Structure of Conserved Domains 1 and 2 of the Human DEAD-box Helicase DDX3X in Complex with the Mononucleotide AMP
2007
Secondary Structure of Vertebrate Telomerase RNA
2000 StandoutNobel
Human PIR1 of the Protein-tyrosine Phosphatase Superfamily Has RNA 5′-Triphosphatase and Diphosphatase Activities
1999
DNA Ligase III Is Recruited to DNA Strand Breaks by a Zinc Finger Motif Homologous to That of Poly(ADP-ribose) Polymerase
1999
The Splicing Factor BBP Interacts Specifically with the Pre-mRNA Branchpoint Sequence UACUAAC
1997 StandoutNobel
Genetic evidence for base pairing between U2 and U6 snRNA in mammalian mRNA splicing
1991 Nature
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Molecular Architecture and Ligand Recognition Determinants for T4 RNA Ligase
2005
Analyses of the Functional Regions of DEAD-Box RNA “Helicases” with Deletion and Chimera Constructs Tested In Vivo and In Vitro
2011
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
RNA helicases — one fold for many functions
2007
Cotranscriptional Spliceosome Assembly Occurs in a Stepwise Fashion and Requires the Cap Binding Complex
2005
The β subunit of Oxytricha telomere-binding protein promotes G-quartet formation by telomeric DNA
1993 Nobel
Backbone tracking by the SF2 helicase NPH-II
2004
Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair
1993 StandoutNobel
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx
1995 StandoutNobel
Cross-Intron Bridging Interactions in the Yeast Commitment Complex Are Conserved in Mammals
1997 StandoutNobel
A newly identified DNA ligase of Saccharomyces cerevisiaeinvolved in RAD52-independent repair of DNA double-strand breaks
1997 StandoutNobel
Translational activation of the lck proto-oncogene
1988 StandoutNatureNobel
Transcriptional mapping and nucleotide sequence of a vaccinia virus gene encoding a polypeptide with extensive homology to DNA ligases
1989
Functional Proteomics Reveals the Biochemical Niche of C. elegans DCR-1 in Multiple Small-RNA-Mediated Pathways
2006 StandoutNobel
Elongation by RNA polymerase II: the short and long of it
2004
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
Nucleases: diversity of structure, function and mechanism
2010
Gal3p and Gal1p interact with the transcriptional repressor Gal80p to form a complex of 1:1 stoichiometry
2002
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
RNA Substrate Specificity and Structure-guided Mutational Analysis of Bacteriophage T4 RNA Ligase 2
2004
The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus
2009
Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin
1997 StandoutNatureNobel
Dead-box proteins: a family affair—active and passive players in RNP-remodeling
2006
Purification of splicing factor SF1, a heat-stable protein that functions in the assembly of a presplicing complex.
1992
Dxo1 is a new type of eukaryotic enzyme with both decapping and 5′-3′ exoribonuclease activity
2012
Mechanism of selective translation of vaccinia virus mRNAs: differential role of poly(A) and initiation factors in the translation of viral and cellular mRNAs
1991
Active Disruption of an RNA-Protein Interaction by a DExH/D RNA Helicase
2001 Science
Helicases: amino acid sequence comparisons and structure-function relationships
1993
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
2016 StandoutNatureNobel
Roles of individual domains in the function of DHX29, an essential factor required for translation of structured mammalian mRNAs
2012
An RNA conformational change between the two chemical steps of group II self-splicing.
1996
Postsynaptic Membrane Fusion and Long-Term Potentiation
1998 StandoutScienceNobel
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
1995 StandoutNobel
Quality Control by DNA Repair
1999 StandoutScienceNobel
Adenylyl Cyclase Amino Acid Sequence: Possible Channel- or Transporter-Like Structure
1989 StandoutScienceNobel
Molecular Cloning and Expression of Human cDNAs Encoding a Novel DNA Ligase IV and DNA Ligase III, an Enzyme Active in DNA Repair and Recombination
1995 StandoutNobel
The yeast SNF2/SWI2 protein has DNA-stimulated ATPase activity required for transcriptional activation.
1993
Two mRNAs that differ by two nontemplated nucleotides encode the amino coterminal proteins P and V of the paramyxovirus SV5
1988
Dual Roles for Spt5 in Pre-mRNA Processing and Transcription Elongation Revealed by Identification of Spt5-Associated Proteins
2003
A General Mechanism for Network-Dosage Compensation in Gene Circuits
2010 StandoutScienceNobel
A novel role for a U5 snRNP protein in 3' splice site selection.
1995
PRP38 encodes a yeast protein required for pre-mRNA splicing and maintenance of stable U6 small nuclear RNA levels.
1992
PRP38 Encodes a Yeast Protein Required for Pre-mRNA Splicing and Maintenance of Stable U6 Small Nuclear RNA Levels
1992
Messenger RNAs of a strongly-expressed late gene of cowpox virus contain 5′-terminal poly(A) sequences.
1987
Synthetic lethal mutations suggest interactions between U5 small nuclear RNA and four proteins required for the second step of splicing.
1992
Purification of the yeast U4/U6⋅U5 small nuclear ribonucleoprotein particle and identification of its proteins
1999
A Targeted Bypass Screen Identifies Ynl187p, Prp42p, Snu71p, and Cbp80p for Stable U1 snRNP/Pre-mRNA Interaction
2009 StandoutNobel
Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex
1994 Science
Reverse Transcriptase Motifs in the Catalytic Subunit of Telomerase
1997 ScienceNobel
TRANSCRIPTION OF EUKARYOTIC PROTEIN-CODING GENES
2000
Antagonism of Catecholamine Receptor Signaling by Expression of Cytoplasmic Domains of the Receptors
1993 StandoutScienceNobel
Mammalian DNA ligase II is highly homologous with vaccinia DNA ligase. Identification of the DNA ligase II active site for enzyme-adenylate formation.
1994
Genetic and Physical Interactions Involving the Yeast Nuclear Cap-Binding Complex
1999
An essential splicing factor, SLU7, mediates 3' splice site choice in yeast.
1992
Bacteriophage T4 RNA ligase 2 (gp24.1) exemplifies a family of RNA ligases found in all phylogenetic domains
2002
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
The scanning model for translation: an update.
1989 Standout
The yeast splicing factor Mud13p is a commitment complex component and corresponds to CBP20, the small subunit of the nuclear cap-binding complex.
1996 StandoutNobel
Protein Displacement by DExH/D "RNA Helicases" Without Duplex Unwinding
2004 Science
Cap-Independent Translation Is Required for Starvation-Induced Differentiation in Yeast
2007 StandoutScienceNobel
Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex
1994 Nature
Messenger RNA Splicing in Yeast: Clues to Why the Spliceosome Is a Ribonucleoprotein
1991 Science
Works of Beate Schwer being referenced
Genetic and Biochemical Analysis of Yeast and Human Cap Trimethylguanosine Synthase
2008
RNA capping enzyme and DNA ligase: a superfamily of covalent nucleotidyl transferases
1995
Prp43 Is an Essential RNA-dependent ATPase Required for Release of Lariat-Intron from the Spliceosome
2002
Functional Domains of the Yeast Splicing Factor Prp22p
2001
Interactions between Fission Yeast Cdk9, Its Cyclin Partner Pch1, and mRNA Capping Enzyme Pct1 Suggest an Elongation Checkpoint for mRNA Quality Control
2003
Dynamic association of capping enzymes with transcribing RNA polymerase II
2000
Characterization of Dominant-negative Mutants of the DEAH-box Splicing Factors Prp22 and Prp16
2002
Structure-guided mutational analysis of T4 RNA ligase 1
2006
The Guanylyltransferase Domain of Mammalian mRNA Capping Enzyme Binds to the Phosphorylated Carboxyl-terminal Domain of RNA Polymerase II
1998
Crystal structure, mutational analysis and RNA-dependent ATPase activity of the yeast DEAD-box pre-mRNA splicing factor Prp28
2014
PRP16 is an RNA-dependent ATPase that interacts transiently with the spliceosome
1991 Nature
The C-terminal domain of T4 RNA ligase 1 confers specificity for tRNA repair
2007
A Function of Yeast mRNA Cap Methyltransferase, Abd1, in Transcription by RNA Polymerase II
2004
Genetic and Biochemical Analysis of the Functional Domains of Yeast tRNA Ligase
2003
A Conserved Domain of Yeast RNA Triphosphatase Flanking the Catalytic Core Regulates Self-association and Interaction with the Guanylyltransferase Component of the mRNA Capping Apparatus
1999
Determinants of eukaryal cell killing by the bacterial ribotoxin PrrC
2010
Tat Stimulates Cotranscriptional Capping of HIV mRNA
2002
RNA Repair: An Antidote to Cytotoxic Eukaryal RNA Damage
2008
Characterization of Human, Schizosaccharomyces pombe, and Candida albicans mRNA Cap Methyltransferases and Complete Replacement of the Yeast Capping Apparatus by Mammalian Enzymes
1999
A new twist on RNA helicases: DExH/D box proteins as RNPases.
2001
Motifs IV and V in the DEAH Box Splicing Factor Prp22 Are Important for RNA Unwinding, and Helicase-defective Prp22 Mutants Are Suppressed by Prp8
2004
Mutational Analyses of Yeast RNA Triphosphatases Highlight a Common Mechanism of Metal-dependent NTP Hydrolysis and a Means of Targeting Enzymes to Pre-mRNAs in Vivo by Fusion to the Guanylyltransferase Component of the Capping Apparatus
1999
A Conformational Rearrangement in the Spliceosome Sets the Stage for Prp22-Dependent mRNA Release
2008
RNA helicase dynamics in pre-mRNA splicing
2000
Accelerated mRNA decay in conditional mutants of yeast mRNA capping enzyme
1998
Yeast mRNA Cap Methyltransferase Is a 50-Kilodalton Protein Encoded by an Essential Gene
1995
Genetic, Physical, and Functional Interactions between the Triphosphatase and Guanylyltransferase Components of the Yeast mRNA Capping Apparatus
1998
Characterization of the NTPase, RNA-Binding, and RNA Helicase Activities of the DEAH-Box Splicing Factor Prp22
2005
Structure-Function Analysis of Yeast mRNA Cap Methyltransferase and High-Copy Suppression of Conditional Mutants by AdoMet Synthase and the Ubiquitin Conjugating Enzyme Cdc34p
2000
Mutations in PRP43 That Uncouple RNA-Dependent NTPase Activity and Pre-mRNA Splicing Function
2006
A conformational rearrangement in the spliceosome is dependent on PRP16 and ATP hydrolysis.
1992
Prp22, a DExH-box RNA helicase, plays two distinct roles in yeast pre-mRNA splicing
1998
Mutational Analysis of the Yeast DEAH-Box Splicing Factor Prp16
1998
Mutational analysis of yeast mRNA capping enzyme.
1994
Vaccinia virus late transcripts generated in vitro have a poly(A) head.
1988
Covalent catalysis in nucleotidyl transfer reactions: essential motifs in Saccharomyces cerevisiae RNA capping enzyme are conserved in Schizosaccharomyces pombe and viral capping enzymes and among polynucleotide ligases.
1994
Mutational Analysis of the Saccharomyces cerevisiae ABD1 Gene: Cap Methyltransferase Activity Is Essential for Cell Growth
1996
Discontinuous transcription or RNA processing of vaccinia virus late messengers results in a 5′ poly(A) leader
1987
SLU7 and a novel activity, SSF1, act during the PRP16-dependent step of yeast pre-mRNA splicing.
1995
Conditional inactivation of mRNA capping enzyme affects yeast pre-mRNA splicing in vivo.
1996