Citation Impact
Citing Papers
On the relationship between folding and chemical landscapes in enzyme catalysis
2008 StandoutNobel
Loss of conformational entropy in protein folding calculated using realistic ensembles and its implications for NMR-based calculations
2014 StandoutNobel
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Consistent blind protein structure generation from NMR chemical shift data
2008 StandoutNobel
Protein homology model refinement by large-scale energy optimization
2018 StandoutNobel
Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble
2018 StandoutNobel
Exploiting conformational dynamics to modulate the function of designed proteins
2023 StandoutNobel
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
2020 StandoutNobel
Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions
2011 StandoutNobel
NMR Structure Determination for Larger Proteins Using Backbone-Only Data
2010 StandoutScienceNobel
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors
2022 StandoutNobel
Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis
2014
Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR
2014
Sculpting conducting nanopore size and shape through de novo protein design
2024 StandoutScienceNobel
Critical assessment of methods of protein structure prediction: Progress and new directions in round XI
2016
Urzymology: Experimental Access to a Key Transition in the Appearance of Enzymes
2014
Incorporation of sensing modalities into de novo designed fluorescence-activating proteins
2021 StandoutNobel
Sampling of structure and sequence space of small protein folds
2022 StandoutNobel
Multistate and functional protein design using RoseTTAFold sequence space diffusion
2024 StandoutNobel
Sparse multidimensional iterative lineshape-enhanced (SMILE) reconstruction of both non-uniformly sampled and conventional NMR data
2016
Atomic model of the type III secretion system needle
2012 StandoutNatureNobel
Protein functional landscapes, dynamics, allostery: a tortuous path towards a universal theoretical framework
2010
Computational Enzyme Design
2013 StandoutNobel
Protein dynamics and conformational disorder in molecular recognition
2009
Accurate design of co-assembling multi-component protein nanomaterials
2014 StandoutNatureNobel
Construction and in vivo assembly of a catalytically proficient and hyperthermostable de novo enzyme
2017
Chemical shift-based methods in NMR structure determination
2018
Protein refolding is required for assembly of the type three secretion needle
2010
Principles for designing ideal protein structures
2012 StandoutNatureNobel
Biology of Amyloid: Structure, Function, and Regulation
2010
Functional Class I and II Amino Acid-activating Enzymes Can Be Coded by Opposite Strands of the Same Gene
2015
ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
2016
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
2019 Standout
Role of backbone strain in de novo design of complex α/β protein structures
2021 StandoutNobel
The coming of age of de novo protein design
2016 StandoutNatureNobel
The EVB as a quantitative tool for formulating simulations and analyzing biological and chemical reactions
2009 StandoutNobel
Reconstruction of Functional β-Propeller Lectins via Homo-oligomeric Assembly of Shorter Fragments
2006
Improved accuracy of 15N–1H scalar and residual dipolar couplings from gradient-enhanced IPAP-HSQC experiments on protonated proteins
2009
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
De Novo Proteins with Life-Sustaining Functions Are Structurally Dynamic
2015
Combined automated NOE assignment and structure calculation with CYANA
2015
Exploring methods to expedite the recording of CEST datasets using selective pulse excitation
2018
MDTraj: A Modern Open Library for the Analysis of Molecular Dynamics Trajectories
2015
Rapid NMR Data Collection
2005
De Novo Enzyme Design Using Rosetta3
2011 StandoutNobel
The Amyloid State of Proteins in Human Diseases
2012 Standout
Exploring the repeat protein universe through computational protein design
2015 StandoutNatureNobel
At the dawn of the 21st century: Is dynamics the missing link for understanding enzyme catalysis?
2009 StandoutNobel
PPM: a side-chain and backbone chemical shift predictor for the assessment of protein conformational ensembles
2012
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
De novo protein design by deep network hallucination
2021 StandoutNatureNobel
Simple yet functional phosphate-loop proteins
2018 StandoutNobel
G-Matrix Fourier Transform NOESY-Based Protocol for High-Quality Protein Structure Determination
2005
Reply to Karplus: Conformational dynamics have no role in the chemical step
2010 StandoutNobel
Improving Protein Expression, Stability, and Function with ProteinMPNN
2024 StandoutNobel
Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA
2016
Converting structural information into an allosteric-energy-based picture for elongation factor Tu activation by the ribosome
2011 StandoutNobel
Multidimensional SuFEx Click Chemistry: Sequential Sulfur(VI) Fluoride Exchange Connections of Diverse Modules Launched From An SOF4 Hub
2017 StandoutNobel
Ketosteroid isomerase provides further support for the idea that enzymes work by electrostatic preorganization
2010 StandoutNobel
In the light of directed evolution: Pathways of adaptive protein evolution
2009 StandoutNobel
15N and 13C- SOFAST-HMQC editing enhances 3D-NOESY sensitivity in highly deuterated, selectively [1H,13C]-labeled proteins
2016
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Electrostatic origin of the mechanochemical rotary mechanism and the catalytic dwell of F1-ATPase
2011 StandoutNobel
Residual Dipolar Couplings in Structure Determination of Biomolecules
2004
An Ancestral Tryptophanyl-tRNA Synthetase Precursor Achieves High Catalytic Rate Enhancement without Ordered Ground-State Tertiary Structures
2016
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Toward Accurate Screening in Computer-Aided Enzyme Design
2009 StandoutNobel
Effects of Point Mutation on Enzymatic Activity: Correlation between Protein Electronic Structure and Motion in Chorismate Mutase Reaction
2010
Perspective: Defining and quantifying the role of dynamics in enzyme catalysis
2016 Nobel
Relative Tolerance of an Enzymatic Molten Globule and Its Thermostable Counterpart to Point Mutation
2008
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Protein Design by Directed Evolution
2008
Enzyme millisecond conformational dynamics do not catalyze the chemical step
2009 StandoutNobel
Carbonic Anhydrase as a Model for Biophysical and Physical-Organic Studies of Proteins and Protein−Ligand Binding
2008
A hybrid NMR/SAXS‐based approach for discriminating oligomeric protein interfaces using R osetta
2014 StandoutNobel
Exhaustive Mutagenesis of Six Secondary Active-Site Residues in Escherichia coli Chorismate Mutase Shows the Importance of Hydrophobic Side Chains and a Helix N-Capping Position for Stability and Catalysis
2007
Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site
2023 StandoutNobel
Simulating the electrostatic guidance of the vectorial translocations in hexameric helicases and translocases
2009 StandoutNobel
Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase
2014 StandoutNobel
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Exploring challenges in rational enzyme design by simulating the catalysis in artificial kemp eliminase
2010 StandoutNobel
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout
Structural Reorganization and Preorganization in Enzyme Active Sites: Comparisons of Experimental and Theoretically Ideal Active Site Geometries in the Multistep Serine Esterase Reaction Cycle
2008
Nonnative Interactions in the FF Domain Folding Pathway from an Atomic Resolution Structure of a Sparsely Populated Intermediate: An NMR Relaxation Dispersion Study
2011 StandoutNobel
Works of Beat Vögeli being referenced
Structure and dynamics of a molten globular enzyme
2007
Detection of C′,Cα correlations in proteins using a new time- and sensitivity-optimal experiment
2005
The Structure of Mouse Cytomegalovirus m04 Protein Obtained from Sparse NMR Data Reveals a Conserved Fold of the m02-m06 Viral Immune Modulator Family
2014
Stereospecific assignments in proteins using exact NOEs
2013
Spatial elucidation of motion in proteins by ensemble-based structure calculation using exact NOEs
2012
Limits on Variations in Protein Backbone Dynamics from Precise Measurements of Scalar Couplings
2007
Longitudinal 1H Relaxation Optimization in TROSY NMR Spectroscopy
2002
Exact Distances and Internal Dynamics of Perdeuterated Ubiquitin from NOE Buildups
2009
Simultaneous NMR Study of Protein Structure and Dynamics Using Conservative Mutagenesis
2008
Measurements of Side-Chain 13C−13C Residual Dipolar Couplings in Uniformly Deuterated Proteins
2004
An enzymatic molten globule: Efficient coupling of folding and catalysis
2004
NMR Determination of Amide N−H Equilibrium Bond Length from Concerted Dipolar Coupling Measurements
2008