Standout Papers
Citation Impact
Citing Papers
Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence
1979 Standout
Atomic-Level Characterization of the Structural Dynamics of Proteins
2010 StandoutScienceNobel
The Anatomy and Taxonomy of Protein Structure
1981 Standout
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
1992 StandoutNatureNobel
Identification, sequencing and expression of an integral membrane protein of the trans-Golgi network (TGN38)
1990
The identification of a novel synaptosomal-associated protein, SNAP-25, differentially expressed by neuronal subpopulations.
1989
A stomatin-like protein necessary for mechanosensation in C. elegans
1995 StandoutNatureNobel
A weighting system and aigorithm for aligning many phylogenetically related sequences
1995
NMR structure of the mouse prion protein domain PrP(121–231)
1996 StandoutNatureNobel
The future of protein secondary structure prediction accuracy
1997
Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle
1989 StandoutNatureNobel
Improvements in protein secondary structure prediction by an enhanced neural network
1990
Regulation of Caenorhabditis elegans degenerin proteins by a putative extracellular domain
1995 StandoutNobel
Scrapie prions: a three-dimensional model of an infectious fragment
1996
Experimental and theoretical studies of the three‐dimensional structure of human interleukin‐4
1991
MUSCLE: multiple sequence alignment with high accuracy and high throughput
2004 Standout
A mutation data matrix for transmembrane proteins
1994
Structure of the protein subunits in the photosynthetic reaction centre of Rhodopseudomonas viridis at 3Å resolution
1985 StandoutNatureNobel
Thermodynamic β -sheet propensities measured using a zinc-finger host peptide
1993 Nature
GABAA-receptor-associated protein links GABAA receptors and the cytoskeleton
1999 Nature
SNAP receptors implicated in vesicle targeting and fusion
1993 StandoutNatureNobel
Protein secondary structure and homology by neural networks The α‐helices in rhodopsin
1988
Improved protein structure prediction using potentials from deep learning
2020 StandoutNatureNobel
Prediction of protein secondary structure and active sites using the alignment of homologous sequences
1987
A novel family of growth factor receptors: A common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors, and the p75 IL-2 receptor β-chain
1989
The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools
1997 Standout
Prediction of secondary structure by evolutionary comparison: Application to the α subunit of tryptophan synthase
1987
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
1994 Standout
Molecular cloning and sequence analysis of mutant alleles of the fission yeast cdc2 protein kinase gene: Implications for cdc2 + protein structure and function
1989 StandoutNobel
The mec-4 gene is a member of a family of Caenorhabditis elegans genes that can mutate to induce neuronal degeneration
1991 StandoutNatureNobel
A strategy for the rapid multiple alignment of protein sequences
1987
Predicting the secondary structure of globular proteins using neural network models
1988
Database of homology‐derived protein structures and the structural meaning of sequence alignment
1991
Site-directed mutagenesis study on DNA binding regions of the mouse homologue of Suppressor of Hairless, RBP-Jx
1994 StandoutNobel
Protein structure prediction
1990
Knowledge‐based protein secondary structure assignment
1995 Standout
A ubiquitin-like system mediates protein lipidation
2000 StandoutNatureNobel
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins
1998 StandoutNatureNobel
Sixty-five years of the long march in protein secondary structure prediction: the final stretch?
2016
The synaptic vesicle cycle: a cascade of protein–protein interactions
1995 StandoutNatureNobel
Mechanisms of intracellular protein transport
1994 StandoutNatureNobel
Universal control mechanism regulating onset of M-phase
1990 StandoutNatureNobel
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
1997 Standout
Structural principles of the globular organization of protein chains. A stereochemical theory of globular protein secondary structure
1974
Erythropoietin structure-function relationships. Mutant proteins that test a model of tertiary structure
1993
The single-disulphide intermediates in the refolding of reduced pancreatic trypsin inhibitor
1974
Structural patterns in globular proteins
1976 StandoutNatureNobel
Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily.
1991
Molecular analysis of the armadillo locus: uniformly distributed transcripts and a protein with novel internal repeats are associated with a Drosophila segment polarity gene.
1989 StandoutNobel
Primary sequence and heterologous expression of nuclear pore glycoprotein p62.
1990
Two-Angstrom Crystal Structure of Oxidized Chromatium High Potential Iron Protein
1974
Limited proteolysis of recombinant human soluble interleukin-2 receptor
1989
Conformational parameters for amino acids in helical, β-sheet, and random coil regions calculated from proteins
1974 Standout
Primary structure analysis of an integral membrane glycoprotein of the nuclear pore.
1989 StandoutNobel
Studies of the Regulatory Mechanism of Ca2+/Calmodulin-dependent protein kinase II
1989
Amplification of N- myc in Untreated Human Neuroblastomas Correlates with Advanced Disease Stage
1984 StandoutScienceNobel
Proposed three-dimensional structure for the cellular prion protein.
1994 StandoutNobel
A simplified representation of protein conformations for rapid simulation of protein folding
1976 StandoutNobel
An integral membrane protein of the pore membrane domain of the nuclear envelope contains a nucleoporin-like region
1993 StandoutNobel
Domain structure of 3-hydroxy-3-methylglutaryl coenzyme A reductase, a glycoprotein of the endoplasmic reticulum.
1985 StandoutNobel
Viral cysteine proteases are homologous to the trypsin-like family of serine proteases: structural and functional implications.
1988
Structure-based conformational preferences of amino acids
1999 StandoutNobel
Prediction of chain turns in globular proteins on a hydrophobic basis
1978 Nature
Amphipathic analysis and possible formation of the ion channel in an acetylcholine receptor.
1984
Translocation of proteins across the endoplasmic reticulum. II. Signal recognition protein (SRP) mediates the selective binding to microsomal membranes of in-vitro-assembled polysomes synthesizing secretory protein.
1981 StandoutNobel
Computer simulation of protein folding
1975 StandoutNatureNobel
A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene
1982 Nature
Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor.
1988
Use of random copolymers to determine the helix-coil stability constants of the naturally occurring amino acids
1978
Identification and Structure of Four Yeast Genes (SLY) That Are Able To Suppress the Functional Loss of YPT1, a Member of the RAS Superfamily
1991
Theory of protein secondary structure and algorithm of its prediction
1983
Prediction of secondary structure for Eco RI endonuclease.
1984 StandoutNobel
Molecular cloning and complete sequence of prion protein cDNA from mouse brain infected with the scrapie agent.
1986
Identification of protein sequence homology by consensus template alignment
1986
Antiparallel and parallel β-strands differ in amino acid residue preferences
1979 Nature
A simple method for displaying the hydropathic character of a protein
1982 Standout
Isolation and sequencing of NOP1. A yeast gene encoding a nucleolar protein homologous to a human autoimmune antigen.
1990 StandoutNobel
Analysis of Conformations of Amino Acid Residues and Prediction of Backbone Topography in Proteins
1974
Multiple tachykinins are produced and secreted upon post-translational processing of the three substance P precursor proteins, α-, β-, and γ-preprotachykinin
1989 StandoutNobel
Three rat preprotachykinin mRNAs encode the neuropeptides substance P and neurokinin A.
1987
Conformational preferences of amino acids in globular proteins
1978 StandoutNobel
Recent progress in multiple sequence alignment: a survey
2002
An attempt to evaluate the influence of neighboring amino acids (n − 1) and (n + 1) on the backbone conformation of amino acid (n) in proteins. Use in predicting the three-dimensional structure of the polypeptide backbone of other proteins
1973
Protein secondary structure prediction with a neural network.
1989
Acetylcholine Receptor Structure, Function, and Evolution
1985
Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
1986 StandoutNatureNobel
Control of Memory Formation Through Regulated Expression of a CaMKII Transgene
1996 StandoutScienceNobel
Isolation and characterization of PEP3, a gene required for vacuolar biogenesis in Saccharomyces cerevisiae.
1991
The human mid-size neurofilament subunit: a repeated protein sequence and the relationship of its gene to the intermediate filament gene family.
1987
The role of the α-helix dipole in protein function and structure
1985
Predicted alpha-helical regions of the prion protein when synthesized as peptides form amyloid.
1992 StandoutNobel
Appearance of Water Channels in Xenopus Oocytes Expressing Red Cell CHIP28 Protein
1992 StandoutScienceNobel
Structural design and molecular evolution of a cytokine receptor superfamily.
1990 Standout
Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau.
1988 StandoutNobel
Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA
1989 StandoutScience
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
The major intrinsic protein (MIP) of the bovine lens fiber membrane: Characterization and structure based on cDNA cloning
1984
Analysis of structural similarities between brain Thy-1 antigen and immunoglobulin domains. Evidence for an evolutionary relationship and a hypothesis for its functional significance
1981
Membrane Fusion: Grappling with SNARE and SM Proteins
2009 StandoutScienceNobel
Sequence analysis of the DNA encoding the Eco RI endonuclease and methylase.
1981
Modeling protein structures: construction and their applications
1993
Coupled prediction of protein secondary and tertiary structure
2003 StandoutNobel
Signal Transduction by the Platelet-Derived Growth Factor Receptor
1989 Science
A new family of yeast nuclear pore complex proteins.
1992 StandoutNobel
A structural census of the current population of protein sequences
1997 StandoutNobel
Logical analysis of the mechanism of protein folding
1973
Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells
1985 StandoutNature
Prediction of protein conformation
1974 Standout
Molecular Biology of Prion Diseases
1991 StandoutScienceNobel
The complete sequence of the human intermediate filament chain keratin 10. Subdomainal divisions and model for folding of end domain sequences.
1988
Discrete amino acid sequences of the alpha 1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis.
1992 StandoutNobel
Perturbation of the secondary structure of the scrapie prion protein under conditions that alter infectivity.
1993
A structural model for the retroviral proteases
1987 Nature
The functional domains of the Drosophila morphogen dorsal: evidence from the analysis of mutants.
1992 StandoutNobel
Molecular characterization of two proteins involved in the excision of the conjugative transposon Tn1545: homologies with other site-specific recombinases.
1989
Cloning and sequence analysis of cDNA for a neuronal cell membrane antigen, HPC-1.
1992
Works of Barry Robson being referenced
Secondary structure prediction: combination of three different methods
1988
Structural properties of signal peptides and their membrane insertion
1980
[32] GOR method for predicting protein secondary structure from amino acid sequence
1996
Influence of the local amino acid sequence upon the zones of the torsional angles .phi. and .psi. adopted by residues in proteins
1991
Further developments of protein secondary structure prediction using information theory
1987
Relationship between helix-coil transition parameters for synthetic polypeptides and helix conformation parameters for globular proteins. A simple model
1976
Conformational properties of amino acid residues in globular proteins
1976
Refined models for computer calculations in protein engineering
1986
Directional Information Transfer in Protein Helices
1972
Analysis of the code relating sequence to conformation in globular proteins. An informational analysis of the role of the residue in determining the conformation of its neighbours in the primary sequence
1974
What is a conservative substitution?
1983
Analysis of the code relating sequence to conformation in globular proteins. Theory and application of expected information
1974
Analysis of the code relating sequence to conformation in globular proteins. Development of a stereochemical alphabet on the basis of intra-residue information
1974
Refined models for computer simulation of protein folding
1979
Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins
1978 Standout
Comparison of predicted and experimentally determined secondary structure of adenyl kinase
1974 StandoutNatureNobel
Analysis of the Code Relating Sequence to Secondary Structure in Proteins
1970 Nature
An algorithm for secondary structure determination in proteins based on sequence similarity
1986
Analysis of the code relating sequence to conformation in globular proteins. The distribution of residue pairs in turns and kinks in the backbone chain
1974
Analysis of the code relating sequence to conformation in proteins: Possible implications for the mechanism of formation of helical regions
1971