Citation Impact
Citing Papers
Extension of Murine Life Span by Overexpression of Catalase Targeted to Mitochondria
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Guidelines for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack
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Predicting Chemotherapy Toxicity in Older Adults With Cancer: A Prospective Multicenter Study
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Monitoring Sedation Status Over Time in ICU Patients
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Multidrug resistance in cancer: role of ATP–dependent transporters
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Development of daunorubicin resistance in tumour cells by induction of carbonyl reduction
2000
Acute Coronary Care in the Elderly, Part I
2007
Clinical Pharmacokinetics of Anxiolytics and Hypnotics in the Elderly
1991
Sleep disorders and their management
1990
Myocet (liposome-encapsulated doxorubicin citrate): a new approach in breast cancer therapy
2002
Estrogen Receptors: How Do They Signal and What Are Their Targets
2007 Standout
A Multifactorial Intervention to Reduce the Risk of Falling among Elderly People Living in the Community
1994 Standout
Alterations of calcium-regulatory proteins in heart failure
1998
Expression and regulation of ryanodine receptor/calcium release channels
1996
Phase I trial of doxorubicin with cyclosporine as a modulator of multidrug resistance.
1994
Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor
1999 Standout
Bladder cancer in the elderly
2009
Delirium in elderly people
2013 Standout
Frequency, Severity, and Treatment of Agitation in Young versus Elderly Patients in the ICU
2000
Phytoestrogens: a review of the present state of research
2003
Biodegradable luminescent porous silicon nanoparticles for in vivo applications
2009 Standout
Hepatic cytochrome P-4503A (CYP3A) activity in the elderly
1992
Anthracyclines: Molecular Advances and Pharmacologic Developments in Antitumor Activity and Cardiotoxicity
2004 Standout
Drug-Induced Hepatotoxicity
2003 Standout
Emergency Hospitalizations for Adverse Drug Events in Older Americans
2011 Standout
Co-delivery of daunomycin and oxaliplatin by biodegradable polymers for safer and more efficacious combination therapy
2012
2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults
2009 Standout
Interference with Calcium-Dependent Mitochondrial Bioenergetics in Cardiac Myocytes Isolated from Doxorubicin-Treated Rats
2001
Timing of New Black Box Warnings and Withdrawals for Prescription Medications
2002 Standout
Aging Biology and Geriatric Clinical Pharmacology
2004
Age‐related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications
2003 Standout
Modeling the Metabolism of Idarubicin to Idarubicinol in Rat Heart: Effect of Rutin and Phenobarbital
2003
Secondary alcohol metabolites mediate iron delocalization in cytosolic fractions of myocardial biopsies exposed to anticancer anthracyclines. Novel linkage between anthracycline metabolism and iron-induced cardiotoxicity.
1995
Incidence and Preventability of Adverse Drug Events Among Older Persons in the Ambulatory Setting
2003 Standout
Anthracycline secondary alcohol metabolite formation in human or rabbit heart: biochemical aspects and pharmacologic implications
2003
Covalent and Noncovalent Interactions in Acute Lethal Cell Injury Caused by Chemicals
1990
A novel system for evaluation of drug mixtures for potential efficacy in treating multidrug resistant cancers
2008
Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells
1996
Impairment of myocardial contractility by anticancer anthracyclines: role of secondary alcohol metabolites and evidence of reduced toxicity by a novel disaccharide analogue
2001
Interactions of Adriamycin aglycones with mitochondria may mediate Adriamycin cardiotoxicity
1994
Pharmacokinetic-Pharmacodynamic Crisis in the Elderly
2006
Myocardial Substrate Metabolism in the Normal and Failing Heart
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Liver Function and Phase I Drug Metabolism in the Elderly
2001
Microfluidic organs-on-chips
2014 Standout
Dexrazoxane in the Prevention of Doxorubicin-Induced Cardiotoxicity
1994
Cardiotoxicity of Chemotherapeutic Agents
2000
A Prospective Pharmacologic Evaluation of Age-Related Toxicity of Adjuvant Chemotherapy in Women with Breast Cancer
2000
Mitochondrial Dysfunction in Cardiac Disease: Ischemia–Reperfusion, Aging, and Heart Failure
2001
Cancer Chemotherapy in Older Adults
1997
Pharmacokinetics of Indomethacin in the Elderly
1993
Anthracycline associated cardiotoxicity in survivors of childhood cancer
2008
Differential regulation of two types of intracellular calcium release channels during end-stage heart failure.
1995
Effect of MEN 10755, a new disaccharide analogue of doxorubicin, on sarcoplasmic reticulum Ca2+ handling and contractile function in rat heart
2000
Death and anti-death: tumour resistance to apoptosis
2002 Standout
Appropriate prescribing in elderly people: how well can it be measured and optimised?
2007 Standout
Factors affecting the pharmacokinetics of pegylated liposomal doxorubicin in patients
2011
Effects of selective phosphodiesterase inhibitors on the polymorphonuclear leukocyte respiratory burst
1990
Adverse Drug Effects, Compliance, and Initial Doses of Antihypertensive Drugs Recommended by the Joint National Committee vs the Physicians' Desk Reference
2001
Epithelial ovarian cancer in the elderly: The memorial sloan-kettering cancer center experience
2010
Anthracycline drug targeting: cytoplasmic versus nuclear – a fork in the road
2001
AN ANGIOTENSIN‐CONVERTING ENZYME INHIBITOR PROTECTS AGAINST DOXORUBICIN‐INDUCED IMPAIRMENT OF CALCIUM HANDLING IN NEONATAL RAT CARDIAC MYOCYTES
1997
Structure and function of “metalloantibiotics”
2003
Comparison of Doxorubicin- and MEN 10755-Induced Long-Term Progressive Cardiotoxicity in the Rat
2000
Doxorubicin-Induced Cardiomyopathy
1998 Standout
External validity of randomised controlled trials: “To whom do the results of this trial apply?”
2005 Standout
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
Sleep Disorders and Aging
1990
Preservation of Fertility in Patients with Cancer
2009 Standout
Treatment tolerance of elderly cancer patients entered onto phase II clinical trials: an Illinois Cancer Center study.
1994
Pharmacokinetic Optimisation of Angiotensin Converting Enzyme (ACE) Inhibitor Therapy
1992
Effect of age and gender on the activity of human hepatic CYP3A
1992
PKA Phosphorylation Dissociates FKBP12.6 from the Calcium Release Channel (Ryanodine Receptor)
2000 Standout
Polymorphonuclear Leukocyte Inhibition by Therapeutic Concentrations of Theophylline Is Mediated by Cyclic-3′, 5′-Adenosine Monophosphate
1988
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
Underrepresentation of Patients 65 Years of Age or Older in Cancer-Treatment Trials
1999 Standout
Cancer of the Ovary
2004 Standout
Cardiac excitation–contraction coupling
2002 StandoutNature
Clinical Pharmacokinetics of Anxiolytics and Hypnotics in the Elderly
1991
Cardiotoxicity of cytotoxic drugs
2003
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2001 Standout
Oxidative Stress in Chronic Obstructive Pulmonary Disease
1997 Standout
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute–Working Group 1996 guidelines
2008 Standout
ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult
2005 Standout
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Oral theophylline for chronic obstructive pulmonary disease
2002
The Exclusion of the Elderly and Women From Clinical Trials in Acute Myocardial Infarction
1992
Magnesium in Man: Implications for Health and Disease
2014 Standout
Proteasome regulation of activation-induced T cell death
1997 StandoutNobel
Prevention of High-Dose Chemotherapy–Induced Cardiotoxicity in High-Risk Patients by Angiotensin-Converting Enzyme Inhibition
2006 Standout
Participation of Patients 65 Years of Age or Older in Cancer Clinical Trials
2003 Standout
Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+
1995 Standout
Management of Cancer in the Older Person: A Practical Approach
2000
Defining inappropriate practices in prescribing for elderly people: a national consensus panel.
1997
Protection from doxorubicin-induced cardiac toxicity in mice with a null allele of carbonyl reductase 1.
2003
Bladder Cancer
2020 Standout
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Human carbonyl reductase overexpression in the heart advances the development of doxorubicin-induced cardiotoxicity in transgenic mice.
2000
Evidence-based guideline update: NSAIDs and other complementary treatments for episodic migraine prevention in adults: [RETIRED]
2012
Aging and Heparin-Related Bleeding
1996
Lung Adjuvant Cisplatin Evaluation: A Pooled Analysis by the LACE Collaborative Group
2008 Standout
Anthracycline Metabolism and Toxicity in Human Myocardium: Comparisons between Doxorubicin, Epirubicin, and a Novel Disaccharide Analogue with a Reduced Level of Formation and [4Fe-4S] Reactivity of Its Secondary Alcohol Metabolite
2000
Protection against daunorubicin cytotoxicity by expression of a cloned human carbonyl reductase cDNA in K562 leukemia cells.
1995
2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation
2015 Standout
Inappropriate Drug Prescribing for the Community-Dwelling Elderly
1994
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Effect of Ryanodine on Sarcoplasmic Reticulum Ca2+Accumulation in Nonfailing and Failing Human Myocardium
1995
Early Detection of Anthracycline Cardiotoxicity and Improvement With Heart Failure Therapy
2015 Standout
Role of iron in anthracycline cardiotoxicity: new tunes for an old song?
1999
Heme-Containing Oxygenases
1996 Standout
Molecular Mechanisms of Myocardial Remodeling
1999 Standout
Doxorubicin selectively inhibits muscle gene expression in cardiac muscle cells in vivo and in vitro.
1990
Potentially Inappropriate Medication Use in a Medicare Managed Care Population: Association with Higher Costs and Utilization
2001
2014 AHA/ACC Guideline for the Management of Patients With Non–ST-Elevation Acute Coronary Syndromes
2014 Standout
An approach to drug induced delirium in the elderly
2004
Predictors of Initial Nontherapeutic Anticoagulation With Unfractionated Heparin in ST-Segment Elevation Myocardial Infarction
2009
Works of Barry J. Cusack being referenced
Aging and drug interactions. I. Effect of cimetidine and smoking on the oxidation of theophylline and cortisol in healthy men.
1987
Daunorubicin cardiotoxicity
2000
Hepatic Drug Metabolism and Aging
1990
Effect of Aging on Cardiac Contractility in a Rat Model of Chronic Daunorubicin Cardiotoxicity
2002
Doxorubicin and doxorubicinol pharmacokinetics and tissue concentrations following bolus injection and continuous infusion of doxorubicin in the rabbit
1993
Anthracycline cardiotoxicity in transgenic mice overexpressing SR Ca2+-ATPase
2003
Doxorubicin cardiomyopathy is associated with a decrease in calcium release channel of the sarcoplasmic reticulum in a chronic rabbit model.
1993
Aging alters the force-frequency relationship and toxicity of oxidative stress in rabbit heart
1991
Sarcoplasmic Reticulum Calcium Release Is Stimulated and Inhibited by Daunorubicin and Daunorubicinol
2000
Doxorubicin and C-13 Deoxydoxorubicin Effects on Ryanodine Receptor Gene Expression
2002
Management of Drug Therapy in the Elderly
1989
Time‐related increases in cardiac concentrations of doxorubicinol could interact with doxorubicin to depress myocardial contractile function
1993
Pharmacokinetic Optimisation of Drug Therapy in Elderly Patients
1995
Daunorubicin-Induced Cardiac Injury in the Rabbit: A Role for Daunorubicinol?
1993
Prevention by dexrazoxane of down‐regulation of ryanodine receptor gene expression in anthracycline cardiomyopathy in the rat
2000
Pharmacokinetics in older persons
2004
Randomized, controlled trial of phytoestrogen in the prophylactic treatment of menstrual migraine
2002
Problems in the Use of Anticancer Drugs in The Elderly
1989
Therapeutic concentrations of theophylline and enprofylline potentiate catecholamine effects and inhibit leukocyte activation
1986
Aging and drug interactions. II. Effect of phenytoin and smoking on the oxidation of theophylline and cortisol in healthy men.
1988
Theophylline clearance in patients with severe chronic obstructive pulmonary disease receiving supplemental oxygen and the effect of acute hypoxemia.
1986
Doxorubicin cardiotoxicity may be caused by its metabolite, doxorubicinol.
1988