Barry E. Kennedy

Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities

Targeting the NAD+ salvage pathway suppresses APC mutation-driven colorectal cancer growth and Wnt/β-catenin signaling via increasing Axin level

Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies

Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis

Niemann-Pick disease type C

Macrophages in immunoregulation and therapeutics

Mitochondrial Dysfunction and Neurodegeneration in Lysosomal Storage Disorders

Recent insights on the role of cholesterol in non-alcoholic fatty liver disease

The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)

The JAK/STAT signaling pathway: from bench to clinic

Intracellular cholesterol transporters and modulation of hepatic lipid metabolism: Implications for diabetic dyslipidaemia and steatosis

Impaired autophagic degradation of lncRNA ARHGAP5-AS1 promotes chemoresistance in gastric cancer

Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks

m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer

Lipids on Trial: The Search for the Offending Metabolite in Niemann-Pick type C Disease

Defective cholesterol trafficking in Niemann‐Pick C‐deficient cells

Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism

Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research

JNK signaling in cancer cell survival

Hepatitis C Virus Replication Depends on Endosomal Cholesterol Homeostasis

MLN64 mediates egress of cholesterol from endosomes to mitochondria in the absence of functional Niemann-Pick Type C1 protein

Pre-Symptomatic Activation of Antioxidant Responses and Alterations in Glucose and Pyruvate Metabolism in Niemann-Pick Type C1-Deficient Murine Brain

NAD+ salvage pathway in cancer metabolism and therapy

TRPM2 channel–mediated regulation of autophagy maintains mitochondrial function and promotes gastric cancer cell survival via the JNK-signaling pathway

Autophagic homeostasis is required for the pluripotency of cancer stem cells

Quantitative Proteome Responses to Oncolytic Reovirus in GM-CSF- and M-CSF-Differentiated Bone Marrow-Derived Cells