Standout Papers
Citation Impact
Citing Papers
Pair—rule segmentation genes regulate the expression of the homeotic selector gene, Deformed
1988
The invected gene of Drosophila: sequence analysis and expression studies reveal a close kinship to the engrailed gene.
1987
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
1992 StandoutNatureNobel
Molecular cloning of sequences from wingless , a segment polarity gene in Drosophila : the spatial distribution of a transcript in embryos
1987
The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains
1988 StandoutScience
Distal-less encodes a homoeodomain protein required for limb development in Drosophila
1989 Nature
The roles of Drosophila cyclins A and B in mitotic control
1990
Posterior pattern formation in C. elegans involves position-specific expression of a gene containing a homeobox
1988 StandoutNobel
A homeodomain substitution changes the regulatory specificity of the Deformed protein in drosophila embryos
1989
A community effect in animal development
1988 StandoutNatureNobel
Control of type-D GABAergic neuron differentiation by C. elegans UNC-30 homeodomain protein
1994 StandoutNatureNobel
Developmental and molecular analysis of Deformed ; a homeotic gene controlling Drosophila head development
1987
The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo
1989 StandoutNatureNobel
The Toll gene of drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein
1988
Isolation of caudal , a Drosophila homeo box-containing gene with maternal expression, whose transcripts form a concentration gradient at the pre-blastoderm stage
1985
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
1990 StandoutNatureNobel
Crystal structure of an engrailed homeodomain-DNA complex at 2.8 Å resolution: A framework for understanding homeodomain-DNA interactions
1990
Two-tiered regulation of spatially patterned engrailed gene expression during Drosophila embryogenesis
1988 Nature
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
A mediator required for activation of RNA polymerase II transcription in vitro
1991 StandoutNatureNobel
The puff-specific Drosophila protein Bj6, encoded by the gene no-on transient A, shows homology to RNA-binding proteins
1990
TheDrosophila engrailedprotein is phosphorylated by a serine-specific protein kinase
1988
Activin signalling and response to a morphogen gradient
1994 StandoutNatureNobel
Isolation of the Drosophila segmentation gene runt and analysis of its expression during embryogenesis.
1988
Primary structure and expression of a product from cut, a locus involved in specifying sensory organ identity in Drosophila
1988 Nature
The structure and function of the homeodomain
1989 Standout
Differential regulation of Ultrabithorax in two germ layers of drosophila
1988
The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors
1988 StandoutNobel
The neurogenic gene Delta of Drosophila melanogaster is expressed in neurogenic territories and encodes a putative transmembrane protein with EGF-like repeats
1987
Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox geneHox-#150;1.6
1992 StandoutNatureNobel
Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors
1991 StandoutNatureNobel
Genetic and molecular characterization of the optomotor-blind gene locus in Drosophila melanogaster.
1990
The Drosophila gene torso encodes a putative receptor tyrosine kinase
1989 StandoutNatureNobel
Homeobox genes and axial patterning
1992 Standout
The sequence specificity of homeodomain-DNA interaction
1988
SPXX, a frequent sequence motif in gene regulatory proteins
1989
Mice with targeted disruptions in the paralogous genes hoxa-3 and hoxd-3 reveal synergistic interactions
1994 StandoutNatureNobel
Genetic analysis of a drosophila neural cell adhesion molecule: Interaction of fasciclin I and abelson tyrosine kinase mutations
1990
A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype
1988
Disruption of c-mos causes parthenogenetic development of unfertilized mouse eggs
1994 StandoutNatureNobel
Absence of radius and ulna in mice lacking hoxa-11 andhoxd-11
1995 StandoutNatureNobel
The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: Comparison with prokaryotic repressors
1989 StandoutNobel
Determination of spatial domains of zygotic gene expression in the Drosophila embryo by the affinity of binding sites for the bicoid morphogen
1989 StandoutNatureNobel
Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes
1988 StandoutNatureNobel
Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis
1989 StandoutNatureNobel
Divergent homeo box proteins recognize similar DNA sequences in Drosophila
1988 Nature
Cyclin A and the retinoblastoma gene product complex with a common transcription factor
1991 StandoutNatureNobel
A role for casein kinase 2α in the Drosophila circadian clock
2002 StandoutNatureNobel
Drosophila hedgehog acts as a morphogen in cellular patterning
1994
Isolation and characterization of the Drosophila gene encoding the TATA box binding protein, TFIID
1990
Universal control mechanism regulating onset of M-phase
1990 StandoutNatureNobel
mec-3, a homeobox-containing gene that specifies differentiation of the touch receptor neurons in C. elegans
1988 StandoutNobel
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
1997 Standout
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
1998 StandoutNatureNobel
Isolation, structure, and expression of labial, a homeotic gene of the Antennapedia Complex involved in Drosophila head development.
1989
DNA sequence encoding the amino-terminal region of the human c-src protein: implications of sequence divergence among src-type kinase oncogenes.
1987
Primary sequence and developmental expression of a novel Drosophila melanogaster src gene.
1987
Region-specific expression of mouse homeobox genes in the embryonic mesoderm and central nervous system.
1987
Molecular analysis of the armadillo locus: uniformly distributed transcripts and a protein with novel internal repeats are associated with a Drosophila segment polarity gene.
1989 StandoutNobel
The Drosophila RBP-J kappa gene encodes the binding protein for the immunoglobulin J kappa recombination signal sequence.
1991 StandoutNobel
Dorsal , an Embryonic Polarity Gene in Drosophila , Is Homologous to the Vertebrate Proto-Oncogene, c- rel
1987 Science
Cross-Regulatory Interactions Among Pair-Rule Genes in Drosophila
1986 Science
Specific expression of the Hox 1.3 homeo box gene in murine embryonic structures originating from or induced by the mesoderm.
1987
Structure of two genes at the gooseberry locus related to the paired gene and their spatial expression during Drosophila embryogenesis.
1987
Homeo Boxes in the Study of Development
1987 Science
A chicken caudal homologue, CHox-cad, is expressed in the epiblast with posterior localization and in the early endodermal lineage
1991
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Hoxa 11 structure, extensive antisense transcription, and function in male and female fertility
1995
Secretion and movement of wingless protein in the epidermis of the Drosophila embryo
1991
Structure and sequence of the Drosophila zeste gene.
1987
The Drosophila developmental gene, engrailed, encodes a sequence-specific DNA binding activity
1985 Nature
Altering the Genome by Homologous Recombination
1989 StandoutScienceNobel
Cloning and characterization of the segment polarity gene cubitus interruptus Dominant of Drosophila.
1990
Isolation, structure, and expression of even-skipped: A second pair-rule gene of Drosophila containing a homeo box
1986
The orthodenticle gene encodes a novel homeo domain protein involved in the development of the Drosophila nervous system and ocellar visual structures.
1990
Expression during embryogenesis of a mouse gene with sequence homology to the Drosophila engrailed gene
1985
Green Fluorescent Protein as a Marker for Gene Expression
1994 StandoutScienceNobel
Transabdominal, a dominant mutant of the Bithorax Complex, produces a sexually dimorphic segmental transformation in Drosophila.
1987 StandoutNobel
HOMEOTIC GENES AND THE HOMEOBOX
1986
Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-II
1990 StandoutNatureNobel
Isolation of the proto-oncogene c-myb from D. melanogaster
1985 StandoutNobel
Establishment and refinement of segmental pattern in the Drosophila embryo: spatial control of engrailed expression by pair-rule genes.
1987
Temporal and spatial relationships between segmentation and homeotic gene expression in Drosophila embryos: distributions of the fushi tarazu, engrailed, Sex combs reduced, Antennapedia, and Ultrabithorax proteins.
1988
Subtle Cerebellar Phenotype in Mice Homozygous for a Targeted Deletion of the En-2 Homeobox
1991 Science
Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats
1985
Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region
1987 StandoutNatureNobel
Impaired Long-Term Potentiation, Spatial Learning, and Hippocampal Development in fyn Mutant Mice
1992 StandoutScienceNobel
The proboscipedia locus of the Antennapedia complex: a molecular and genetic analysis.
1988
Organization of anterior pattern in the Drosophila embryo by the maternal gene bicoid
1986 StandoutNatureNobel
Expression of a MyoD family member prefigures muscle pattern in Drosophila embryos.
1990
Conservation of a large protein domain in the segmentation gene paired and in functionally related genes of Drosophila
1986
The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential.
1995
Hierarchical Inductions of Cell States: A Model for Segmentation in Drosophila
1986
yes-related protooncogene, syn, belongs to the protein-tyrosine kinase family.
1986
A murine even-skipped homologue, Evx 1, is expressed during early embryogenesis and neurogenesis in a biphasic manner.
1990
A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family
1987 Nature
Spatial Programming of Gene Expression in Early Drosophila Embryogenesis
1986
Molecular characterization of Shaker, a Drosophila gene that encodes a potassium channel
1987
Homoeo-domain homology in yeast MATα2 is essential for repressor activity
1986 Nature
Molecular organization of the decapentaplegic gene in Drosophila melanogaster.
1990
Molecular characterization of the zerknüllt region of the Antennapedia gene complex in Drosophila.
1987
Region-Specific Expression of Two Mouse Homeo Box Genes
1987 Science
Isolation of two tissue-specific Drosophila paired box genes, Pox meso and Pox neuro.
1989
En-1 and En-2, two mouse genes with sequence homology to the Drosophila engrailed gene: expression during embryogenesis.
1987
Crystal Structure of DNA Photolyase from Escherichia coli
1995 StandoutScienceNobel
Determination of Anteroposterior Polarity in Drosophila
1987 StandoutScienceNobel
CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES
1997 Standout
Expression of homeo box genes during mouse development: a review.
1988
Characterization and localization of the even-skipped protein of Drosophila.
1987
Expression and embryonic function of empty spiracles: a Drosophila homeo box gene with two patterning functions on the anterior-posterior axis of the embryo.
1989
Crystal Structure of a CAP-DNA Complex: the DNA Is Bent by 90°
1991 StandoutScienceNobel
A mouse gene homologous to the Drosophila gene caudal is expressed in epithelial cells from the embryonic intestine.
1988
Homeo box gene expression in anterior and posterior regions of the Drosophila embryo.
1986
Development of embryonic pattern in D. melanogaster as revealed by accumulation of the nuclear engrailed protein
1985
Drosophila melanogaster homologs of the raf oncogene.
1987
Systematic method for the detection of potential λ Cro-like DNA-binding regions in proteins
1987
Novel protein-tyrosine kinase gene (hck) preferentially expressed in cells of hematopoietic origin.
1987
Drosophila and vertebrate myb proteins share two conserved regions, one of which functions as a DNA-binding domain.
1987
Developmental and spatial patterns of expression of the mouse homeobox gene,Hox2.1
1987
Molecular analysis of odd-skipped, a zinc finger encoding segmentation gene with a novel pair-rule expression pattern.
1990 StandoutNobel
pen repeat sequences are GGN clusters and encode a glycine-rich domain in a Drosophila cDNA homologous to the rat helix destabilizing protein.
1987
Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity.
1990 StandoutNobel
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
Spatial restriction in expression of a mouse homoeo box locus within the central nervous system
1986 Nature
Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS
1990 StandoutScienceNobel
Hox-1.6: a mouse homeo-box-containing gene member of the Hox-1 complex.
1987
A thousand and one protein kinases
1987
Gap genes define the limits of antennapedia and bithorax gene expression during early development in Drosophila.
1988
Expression of the caudal gene in the germ line of Drosophila: Formation of an RNA and protein gradient during early embryogenesis
1987
Homeo box genes of the Antennapedia and Bithorax Complexes of Drosophila
1985
The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains.
1988 Nobel
Cloning of Genomic and Complementary DNA from Shaker , a Putative Potassium Channel Gene from Drosophila
1987 Science
Sevenless , a Cell-Specific Homeotic Gene of Drosophila , Encodes a Putative Transmembrane Receptor with a Tyrosine Kinase Domain
1987 Science
Structure and nucleotide sequence of a Drosophila melanogaster protein kinase C gene.
1987
The Mating of a Fly
1994 StandoutScienceNobel
Proliferation of both somatic and germ cells is affected in the Drosophila mutants of raf proto-oncogene.
1988
Isolation and sequencing of cDNA clones encoding alpha and beta subunits of Drosophila melanogaster casein kinase II.
1987
High-affinity binding sites for the Deformed protein are required for the function of an autoregulatory enhancer of the Deformed gene.
1991
Neurexins: Synaptic Cell Surface Proteins Related to the α-Latrotoxin Receptor and Laminin
1992 StandoutScienceNobel
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of Drosophila.
1991
Expression of N-myc in teratocarcinoma stem cells and mouse embryos
1985 StandoutNatureNobel
Role of segment polarity genes in the definition and maintenance of cell states in the Drosophila embryo
1988
Structural organization and sequence of the homeotic gene Antennapedia of Drosophila melanogaster.
1986
The engrailed locus of drosophila: In situ localization of transcripts reveals compartment-specific expression
1985
The molecular basis for metameric pattern in the Drosophila embryo
1987
Structure of the segmentation gene paired and the Drosophila PRD gene set as part of a gene network
1986
Cross-regulatory interactions among the gap genes of Drosophila
1986 Nature
Immunocytochemical localization of the neuron-specific form of the c- src gene product, pp60c-src(+), in rat brain
1990
slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains.
1990
The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.
1988
Two proto-oncogenes implicated in mammary carcinogenesis, int-1 and int-2, are independently regulated during mouse development.
1986
The Drosophila neurogenic locus mastermind encodes a nuclear protein unusually rich in amino acid homopolymers.
1990
Isolation of a mouse cDNA coding for a developmentally regulated, testis-specific transcript containing homeo box homology.
1986
Works of Barry Drees being referenced
The nucleotide sequence and the tissue-specific expression of Drosophila c-src
1985 StandoutNobel
The engrailed locus of D. melanogaster provides an essential zygotic function in precellular embryos
1985
The transcription unit of the Drosophila engrailed locus: an unusually small portion of a 70,000 bp gene.
1987
The engrailed Locus of Drosophila melanogaster: Genetic, Developmental, and Molecular Studies
1985
Molecular cloning of engrailed: a gene involved in the development of pattern in drosophila melanogaster
1985
The engrailed locus of drosophila: Structural analysis of an embryonic transcript
1985