Citation Impact
Citing Papers
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
2016 StandoutScienceNobel
CRISPR/Cas9 in Genome Editing and Beyond
2016
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
Rationally engineered Cas9 nucleases with improved specificity
2015 StandoutScience
A Pan-cancer Analysis of the Expression and Clinical Relevance of Small Nucleolar RNAs in Human Cancer
2017
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
2022 StandoutNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
A view on drug resistance in cancer
2019 StandoutNature
High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
2016 StandoutNature
Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements
2015
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
2014 Standout
Classification and evolution of type II CRISPR-Cas systems
2014 StandoutNobel
Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators
2015
Post-translational Regulation of Cas9 during G1 Enhances Homology-Directed Repair
2016
A CRISPR–dCas Toolbox for Genetic Engineering and Synthetic Biology
2018
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
Enabling functional genomics with genome engineering
2015
Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9
2016
The Cancer Genome Atlas Pan-Cancer analysis project
2013 Standout
Applications of CRISPR–Cas systems in neuroscience
2015
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
2017 StandoutNatureNobel
Inhibition of CRISPR-Cas systems by mobile genetic elements
2017
The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
2016 StandoutNatureNobel
From Krebs to clinic: glutamine metabolism to cancer therapy
2016 Standout
Massively parallel determination and modeling of endonuclease substrate specificity
2014 StandoutNobel
Programmable RNA recognition and cleavage by CRISPR/Cas9
2014 StandoutNatureNobel
Targeting apoptosis in cancer therapy
2020 Standout
CRISPR/Cas9-Based Engineering of the Epigenome
2017
Beyond editing: repurposing CRISPR–Cas9 for precision genome regulation and interrogation
2015
Determinants and clinical implications of chromosomal instability in cancer
2018
In vivo genome editing using Staphylococcus aureus Cas9
2015 StandoutNature
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
Development and Applications of CRISPR-Cas9 for Genome Engineering
2014 Standout
Conformational control of DNA target cleavage by CRISPR–Cas9
2015 StandoutNatureNobel
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
The next generation of CRISPR–Cas technologies and applications
2019
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
DEBrowser: interactive differential expression analysis and visualization tool for count data
2019
Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation
2020 StandoutNobel
Synthetic lethality and cancer
2017
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA
2016
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis
2017 Nature
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Discovery and saturation analysis of cancer genes across 21 tumour types
2014 StandoutNature
Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications
2017 StandoutNobel
Persistent Alterations in Microglial Enhancers in a Model of Chronic Pain
2016
CRISPR/Cas9-Mediated Genome Editing of Epigenetic Factors for Cancer Therapy
2015
A Cas9–guide RNA complex preorganized for target DNA recognition
2015 StandoutScienceNobel
Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems
2016 Science
Dynamics of CRISPR-Cas9 genome interrogation in living cells
2015 StandoutScienceNobel
CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine
2017
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning
2015 StandoutScienceNobel
Pain regulation by non-neuronal cells and inflammation
2016 StandoutScience
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference
2014 StandoutNobel
Rational design of a split-Cas9 enzyme complex
2015 StandoutNobel
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
A systematic dissection of determinants and consequences of snoRNA-guided pseudouridylation of human mRNA
2022 StandoutNobel
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Engineering of temperature- and light-switchable Cas9 variants
2013 StandoutNobel
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Nucleosomes impede Cas9 access to DNA in vivo and in vitro
2016
Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides
2020 StandoutNobel
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of Barbara Tabak being referenced
Pan-cancer patterns of somatic copy number alteration
2013
Functional annotation of native enhancers with a Cas9–histone demethylase fusion
2015
Comparative Analysis of Immune Cells Reveals a Conserved Regulatory Lexicon
2018