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Citing Papers
Notch Signaling Determines the M1 versus M2 Polarization of Macrophages in Antitumor Immune Responses
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The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps
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CD4 + CD25 + Foxp3 + regulatory T cells induce alternative activation of human monocytes/macrophages
2007
Membrane-tethered mucin-like polypeptides sterically inhibit binding and slow fusion kinetics of influenza A virus
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HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype
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Identification of a Subpopulation of Macrophages in Mammary Tumor–Bearing Mice That Are Neither M1 nor M2 and Are Less Differentiated
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De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
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Analysis of CC chemokine and chemokine receptor expression in solid ovarian tumours
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A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF- B and enhanced IRF-3/STAT1 activation)
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Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns
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Inflammation and cancer
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Actions of the chemotactic cytokines MCP‐1, MCP‐2, MCP‐3, RANTES, MIP‐1α and MIP‐1β on human monocytes
1995
Dectin-1: a signalling non-TLR pattern-recognition receptor
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The role of tumour‐associated macrophages in tumour progression: implications for new anticancer therapies
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Physical Principles of Membrane Shape Regulation by the Glycocalyx
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Altered macrophage differentiation and immune dysfunction in tumor development
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Role of tumor-associated macrophages in tumor progression and invasion
2006
Tumor-Associated Macrophages in Breast Cancer
2002
Distribution and infection of langerhans cells in the skin of HIV-infected healthy subjects and AIDS patients
1993
Structural recognition and functional activation of FcγR by innate pentraxins
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Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
2002 Standout
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
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Targeting tumor-associated macrophages as a novel strategy against breast cancer
2006
Chemokines: agents for the immunotherapy of cancer?
2002
Tumour-associated macrophage infiltration, neovascularization and aggressiveness in malignant melanoma: role of monocyte chemotactic protein-1 and vascular endothelial growth factor-A
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Macrophages, innate immunity and cancer: balance, tolerance, and diversity
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The role of myeloid cells in the promotion of tumour angiogenesis
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Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Impaired tumor growth in colony-stimulating factor 1 (CSF-1)-deficient, macrophage-deficientop/op mouse: Evidence for a role of CSF-1-dependent macrophages in formation of tumor stroma
1996
Secretion of epidermal growth factor by macrophages associated with breast carcinoma
1993
Pattern recognition receptors in the immune response against dying cells
2008
Macrophage migration and gene expression in response to tumor hypoxia
2005
Macrophage receptors implicated in the “adaptive” form of innate immunity
2007
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
C1q and its growing family
2006
Neutrophils in the activation and regulation of innate and adaptive immunity
2011 Standout
Purification and identification of chemokines potentially involved in kidney-specific metastasis by a murine lymphoma variant: induction of migration and NFκB activation
1998
Significant correlation of monocyte chemoattractant protein-1 expression with neovascularization and progression of breast carcinoma
2001
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
CD4+ T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages
2009
The impact of T‐cell immunity on ovarian cancer outcomes
2008
Targeting Stromal-cancer Cell Interactions with siRNAs
2008
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
2020 Standout
Vα24-invariant NKT cells mediate antitumor activity via killing of tumor-associated macrophages
2009
Macrophage Responses to Hypoxia
2005
Stromal cell‐derived CSF‐1 blockade prolongs xenograft survival of CSF‐1‐negative neuroblastoma
2009
Human Monocyte Chemoattractant Protein-1 (MCP-1)
1991
A timeline of tumour-associated macrophage biology
2023
C1q and tumor necrosis factor superfamily: modularity and versatility
2004
The absence of CCL2 expression in cervical carcinoma is associated with increased survival and loss of heterozygosity at 17q11.2
2006
The Classical Complement Cascade Mediates CNS Synapse Elimination
2007 Standout
Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN
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Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor
1993
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
2010 Standout
Endotoxin tolerance: new mechanisms, molecules and clinical significance
2009 Standout
Trophic macrophages in development and disease
2009
Hyaluronan-dependent pericellular matrix☆
2007
Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors
2007
Chemokines in cancer
2002
Inflammation and cancer: back to Virchow?
2001 Standout
High tumour islet macrophage infiltration correlates with improved patient survival but not with EGFR mutations, gene copy number or protein expression in resected non-small cell lung cancer
2008
Atherosclerosis — An Inflammatory Disease
1999 Standout
CCL2 and Interleukin-6 Promote Survival of Human CD11b+ Peripheral Blood Mononuclear Cells and Induce M2-type Macrophage Polarization
2009
Macrophage plasticity and polarization: in vivo veritas
2012 Standout
Immunopathogenic Mechanisms in Human Immunodeficiency Virus (HIV) Infection
1991
Enhanced tumour growth in the rat liver after selective elimination of Kupffer cells
1993
The cell surface mucin MUC1 limits the severity of influenza A virus infection
2017
Human monocyte chemoattractant protein-1 (MCP-1)
1990
Cancer and the chemokine network
2004 Standout
Regulation by HIV Rev depends upon recognition of splice sites
1989 StandoutNobel
Cancer-related inflammation
2008 StandoutNature
Chemokine expression is associated with the accumulation of tumour associated macrophages (TAMs) and progression in human colorectal cancer
2007
Inflammation and breast cancer. Microenvironmental factors regulating macrophage function in breast tumours: hypoxia and angiopoietin-2
2007
Sexual Dimorphism in Innate Immunity
2017
The Macrophage Growth Factor CSF-1 in Mammary Gland Development and Tumor Progression
2002
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
Macrophages direct tumour histology and clinical outcome in a colon cancer model
2005
Dendritic cell–endothelial cell cross-talk in angiogenesis
2007
Chemokine biology in cancer
2002
The detection and localization of monocyte chemoattractant protein-1 (MCP-1) in human ovarian cancer.
1995
Tumors and inflammatory infiltrates: Friends or foes?
2002
The Expression of Monocyte Chemotactic Protein-1 in Papillary Thyroid Carcinoma Is Correlated with Lymph Node Metastasis and Tumor Recurrence
2008
Increased Survival, Proliferation, and Migration in Metastatic Human Pancreatic Tumor Cells Expressing Functional CXCR4
2004
Interleukin 1 induces expression of the human immunodeficiency virus alone and in synergy with interleukin 6 in chronically infected U1 cells: inhibition of inductive effects by the interleukin 1 receptor antagonist.
1994
Detection and localization of MIP‐3α/LARC/exodus, a macrophage proinflammatory chemokine, and its CCR6 receptor in human pancreatic cancer
1999
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
2016 Standout
Early protection against pathogenic virus infection at a mucosal challenge site after vaccination with attenuated simian immunodeficiency virus
2004 StandoutNobel
Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking
1998 StandoutScienceNobel
Transforming growth factor beta suppresses human immunodeficiency virus expression and replication in infected cells of the monocyte/macrophage lineage.
1991
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8 + T cells in a spectrum of human MHC I haplotypes
2007 StandoutNobel
Targeting CCL2 with Systemic Delivery of Neutralizing Antibodies Induces Prostate Cancer Tumor RegressionIn vivo
2007
High Expression of Macrophage Colony-Stimulating Factor in Peritumoral Liver Tissue Is Associated With Poor Survival After Curative Resection of Hepatocellular Carcinoma
2008
Epithelial cancer cell migration: a role for chemokine receptors?
2001
Defective lymphocyte chemotaxis in β-arrestin2- and GRK6-deficient mice
2002 StandoutNobel
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
Enhanced Apoptotic Cell Clearance Capacity and B Cell Survival Factor Production by IL-10-Activated Macrophages: Implications for Burkitt’s Lymphoma
2005
Fc receptors in antibody‐dependent enhancement of viral infections
2015
RANTES expression is a predictor of survival in stage I lung adenocarcinoma.
2002
Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8 + T Cells
1995 StandoutScience
Mononuclear phagocytes egress from an in vitro model of the vascular wall by migrating across endothelium in the basal to apical direction: role of intercellular adhesion molecule 1 and the CD11/CD18 integrins.
1996
Programmed assembly of 3-dimensional microtissues with defined cellular connectivity
2009 StandoutNobel
The Human Immunodeficiency Virus: Infectivity and Mechanisms of Pathogenesis
1988 StandoutScience
Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1
1996
A Phase II Study of Etanercept (Enbrel), a Tumor Necrosis Factor α Inhibitor in Patients with Metastatic Breast Cancer
2004
The CC chemokine RANTES in breast carcinoma progression: regulation of expression and potential mechanisms of promalignant activity.
2002
Analysis of chemokines and chemokine receptor expression in ovarian cancer ascites.
2002
The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins
2011 StandoutNobel
Granulocyte Macrophage Colony-Stimulating Factor Inhibits Breast Cancer Growth and Metastasis by Invoking an Anti-Angiogenic Program in Tumor-Educated Macrophages
2009
Plasticity of Macrophage Function during Tumor Progression: Regulation by Distinct Molecular Mechanisms
2008
Elevated expression of the CC chemokine regulated on activation, normal T cell expressed and secreted (RANTES) in advanced breast carcinoma.
1999
Requirement of Mip-1α for an Inflammatory Response to Viral Infection
1995 StandoutScienceNobel
Bacterial Lipopolysaccharide Rapidly Inhibits Expression of C–C Chemokine Receptors in Human Monocytes
1997
Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2
1997 StandoutNobel
Chemotaxis in a lymphocyte cell line transfected with C-C chemokine receptor 2B: Evidence that directed migration is mediated by βγ dimers released by activation of Gαi-coupled receptors
1997
Low-Level Monocyte Chemoattractant Protein-1 Stimulation of Monocytes Leads to Tumor Formation in Nontumorigenic Melanoma Cells
2001
Alternative Activation of Macrophages: An Immunologic Functional Perspective
2008 Standout
Inhibition of tumor growth by elimination of granulocytes.
1995
Regulatory Activity of Autocrine IL-10 on Dendritic Cell Functions
2001
Study of Etanercept, a Tumor Necrosis Factor-Alpha Inhibitor, in Recurrent Ovarian Cancer
2005
The intriguing role of polymorphonuclear neutrophils in antitumor reactions
2001
Ovarian Cancer Cells Polarize Macrophages Toward A Tumor-Associated Phenotype
2006
Quantitative assessment of the leukocyte infiltrate in ovarian cancer and its relationship to the expression of C-C chemokines.
1997
Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues
2004
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Replication of HIV-1 in Dendritic Cell-Derived Syncytia at the Mucosal Surface of the Adenoid
1996 StandoutScienceNobel
CCR7 is involved in the migration of neutrophils to lymph nodes
2010
Anti-HIV-1 and chemotactic activities of human stromal cell-derived factor 1α (SDF-1α) and SDF-1β are abolished by CD26/dipeptidyl peptidase IV-mediated cleavage
1998 StandoutNobel
Regulation of the Chemokine Receptor CXCR4 by Hypoxia
2003
The Viral Chemokine Macrophage Inflammatory Protein-II Is a Selective Th2 Chemoattractant
1998
Macrophage Differentiation and Polarization via Phosphatidylinositol 3-Kinase/Akt–ERK Signaling Pathway Conferred by Serum Amyloid P Component
2011
Colony-Stimulating Factor-1 Blockade by Antisense Oligonucleotides and Small Interfering RNAs Suppresses Growth of Human Mammary Tumor Xenografts in Mice
2004
Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor κB
2009
A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells.
1993 StandoutNobel
A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels
1998 StandoutNobel
Differential regulation of the JE gene encoding the monocyte chemoattractant protein (MCP-1) in cervical carcinoma cells and derived hybrids
1994 StandoutNobel
Tumor-induced immune dysfunction: the macrophage connection
1998
Pathogenesis of Infection with Human Immunodeficiency Virus
1987
HIV replication in CD4+T cells of HIV-infected individuals is regulated by a balance between the viral suppressive effects of endogenous β-chemokines and the viral inductive effects of other endogenous cytokines
1996 StandoutNobel
Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8 + T cells
2010 StandoutNobel
Tumor Necrosis Factor α As a New Target for Renal Cell Carcinoma: Two Sequential Phase II Trials of Infliximab at Standard and High Dose
2007
Tumor-Conditioned Macrophages Secrete Migration-Stimulating Factor: A New Marker for M2-Polarization, Influencing Tumor Cell Motility
2010
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
2014 StandoutNobel
Significance of monocyte chemoattractant protein-1 in angiogenesis and survival in colorectal liver metastases
2009
Dendritic Cells Exposed to Human Immunodeficiency Virus Type-1 Transmit a Vigorous Cytopathic Infection to CD4 + T Cells
1992 StandoutScienceNobel
Apoptosis in AIDS
1993 StandoutScienceNobel
Colony-stimulating factor-1 antisense treatment suppresses growth of human tumor xenografts in mice.
2002
Interleukin-1 and interleukin-1 antagonism
1991 Standout
Immune mechanisms in atherosclerosis.
1989
Immune Mechanisms in Atherosclerosis
2001
Sepsis: Multiple Abnormalities, Heterogeneous Responses, and Evolving Understanding
2013
Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails.
1994
Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals
2009
Macrophage arginase promotes tumor cell growth and suppresses nitric oxide-mediated tumor cytotoxicity.
2001
Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation
2010
The CC chemokine MCP-1/CCL2 in pancreatic cancer progression: regulation of expression and potential mechanisms of antimalignant activity.
2003
Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides
2020 StandoutNobel
Works of Barbara Bottazzi being referenced
p50 Nuclear Factor-κB Overexpression in Tumor-Associated Macrophages Inhibits M1 Inflammatory Responses and Antitumor Resistance
2006
Antiviral Activity of the Long Chain Pentraxin PTX3 against Influenza Viruses
2008
Interleukin-1-inducible genes in endothelial cells. Cloning of a new gene related to C-reactive protein and serum amyloid P component.
1992
Multimer Formation and Ligand Recognition by the Long Pentraxin PTX3
1997
The yin-yang of long pentraxin PTX3 in inflammation and immunity
2014
Pentraxins as a key component of innate immunity
2005
The Role of Macrophages in the Regulation of Primary Tumor Growth
1991
Endogenous PTX3 translocates at the membrane of late apoptotic human neutrophils and is involved in their engulfment by macrophages
2008
Identification of MIP-1α/LD78 as a Monocyte Chemoattractant Released by the HTLV-I-Transformed Cell Line MT4
1995
A chemoattractant expressed in human sarcoma cells (tumor‐derived chemotactic factor, TDCF) is identical to monocyte chemoattractant protein‐1/monocyte chemotactic and activating factor (MCP‐1/MCAF)
1990
Complexity and Complementarity of Outer Membrane Protein A Recognition by Cellular and Humoral Innate Immunity Receptors
2005
The origin and function of tumor-associated macrophages
1992
Macrophage infiltration and growth of sarcoma clones expressing different amounts of monocyte chemotactic protein/JE
1991
Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response
2002 Nature
Circulating levels of the long pentraxin PTX3 correlate with severity of infection in critically ill patients
2001
Biochemical and functional characterization of the interaction between pentraxin 3 and C1q
2003
The long pentraxin PTX3 binds to apoptotic cells and regulates their clearance by antigen-presenting dendritic cells
2000
Tumor‐derived chemotactic factor(S) from human ovarian carcinoma: Evidence for a role in the regulation of macrophage content of neoplastic tissues
1985
Interaction of C1q with IgG1, C-reactive Protein and Pentraxin 3: Mutational Studies Using Recombinant Globular Head Modules of Human C1q A, B, and C Chains
2006
Monocyte chemotactic cytokine gene transfer modulates macrophage infiltration, growth and susceptibility to IL-2 therapy of a murine melanoma
1991
Role of complement and Fcγ receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatus
2010
Regulation of the Macrophage Content of Neoplasms by Chemoattractants
1983 Science
Chemotactic activity for mononuclear phagocytes of culture supernatants from murine and human tumor cells: Evidence for a role in the regulation of the macrophage content of neoplastic tissues
1983
The long pentraxin PTX3 as a link among innate immunity, inflammation, and female fertility
2006
PENTRAXINS AT THE CROSSROADS BETWEEN INNATE IMMUNITY, INFLAMMATION, MATRIX DEPOSITION, AND FEMALE FERTILITY
2004
The signal transduction pathway involved in the migration induced by a monocyte chemotactic cytokine.
1991
Granulocyte colony-stimulating factor (G-CSF) gene transduction in murine adenocarcinoma drives neutrophil-mediated tumor inhibition in vivo. Neutrophils discriminate between G-CSF-producing and G-CSF-nonproducing tumor cells
1992
Regulation of PTX3, a key component of humoral innate immunity in human dendritic cells: stimulation by IL-10 and inhibition by IFN-γ
2006
Monocyte chemotactic cytokine gene transfer modulates macrophage infiltration, growth, and susceptibility to IL-2 therapy of a murine melanoma.
1992
PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization
2004
Inducible expression of PTX3, a new member of the pentraxin family, in human mononuclear phagocytes
1994
Selective recognition of fibroblast growth factor-2 by the long pentraxin PTX3 inhibits angiogenesis
2004
Monocyte function in intravenous drug abusers with lymphadenopathy syndrome and in patients with acquired immunodeficiency syndrome: selective impairment of chemotaxis.
1985
Defective Expression of the Monocyte Chemotactic Protein-1 Receptor CCR2 in Macrophages Associated with Human Ovarian Carcinoma
2000
Origin and regulation of tumor-associated macrophages: the role of tumor-derived chemotactic factor
1986
An Integrated View of Humoral Innate Immunity: Pentraxins as a Paradigm
2009
Autocrine Production of IL-10 Mediates Defective IL-12 Production and NF-κB Activation in Tumor-Associated Macrophages
2000
Expression of c-fos proto-oncogene in tumor-associated macrophages.
1990