Citation Impact
Citing Papers
Hallmarks of Cancer: The Next Generation
2011 Standout
Localization of cystic fibrosis locus to human chromosome 7cen–q22
1985 Nature
Telomere reduction in human colorectal carcinoma and with ageing
1990 Nature
The Huntington's disease candidate region exhibits many different haplotypes
1992
A gene encoding a fibroblast growth factor receptor isolated from the Huntington disease gene region of human chromosome 4
1991
Increased recombination adjacent to the Huntington disease-linked D4S10 marker
1991
Hayflick, his limit, and cellular ageing
2000
Essential role of mouse telomerase in highly proliferative organs
1998 StandoutNatureNobel
Radiation hybrid map spanning the huntington disease gene region of chromosome 4
1992
The telomeric 60 kb of chromosome arm 4p is homologous to telomeric regions on 13p, 15p, 21p, and 22p
1992
The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
1989
Mapping of cosmid clones in Huntington's disease region of chromosome 4
1991
Lack of linkage of familial Wilms' tumour to chromosomal band 11 p13
1988 Nature
Mitochondrial genome variation and the origin of modern humans
2000 StandoutNatureNobel
Instability and decay of the primary structure of DNA
1993 StandoutNatureNobel
Telomere end-replication problem and cell aging
1992 StandoutNobel
A genetic model for colorectal tumorigenesis
1990 Standout
A mutant with a defect in telomere elongation leads to senescence in yeast
1989 StandoutNobel
Telomere states and cell fates
2000 StandoutNatureNobel
The CpG dinucleotide and human genetic disease
1988
Human telomeres contain at least three types of G–rich repeat distributed non-randomly
1989
Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA
1997 StandoutNobel
Functional Characterization and Developmental Regulation of Mouse Telomerase RNA
1995 StandoutScienceNobel
TRF2 Protects Human Telomeres from End-to-End Fusions
1998
Tumor suppressor genes
1991 Standout
The roles of telomeres and telomerase in cell life span
1996
Telomeres shorten during ageing of human fibroblasts
1990 StandoutNatureNobel
Telomeres, telomerase and senescence
1990 StandoutNobel
New DNA markers in the Huntington's disease gene candidate region
1991
Runaway telomere elongation caused by telomerase RNA gene mutations
1995 StandoutNatureNobel
Familial predisposition to Wilms' tumour does not map to the short arm of chromosome 11
1988 Nature
Telomeres and senescence: The history, the experiment, the future
1998 StandoutNobel
Generation and characterization of irradiation hybrids of human chromosome 4
1991
Characterization of a yeast artificial chromosome contig spanning the Huntington's disease gene candidate region
1992
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice
1999 StandoutNobel
A search for restriction fragment length polymorphism on the human Y chromosome
1989
Telomere loss: mitotic clock or genetic time bomb?
1991
Cloning of human telomeres by complementation in yeast
1989 Nature
The mosaic that is our genome
2003 StandoutNatureNobel
Telomeric repeat from T. thermophila cross hybridizes with human telomeres
1988 StandoutNatureNobel
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
1989 StandoutNatureNobel
Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination
1998 StandoutNatureNobel
Cyclin A and the retinoblastoma gene product complex with a common transcription factor
1991 StandoutNatureNobel
Genomic mismatch scanning: a new approach to genetic linkage mapping
1993 StandoutNobel
In vivo loss of telomeric repeats with age in humans
1991
Telomeric structure in cells with chromosome end associations
1993
The telomerase reverse transcriptase: components and regulation
1998
In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs
1990 StandoutNatureNobel
Cloning of the α–adducin gene from the Huntington's disease candidate region of chromosome 4 by exon amplification
1992
Control of telomere length by the human telomeric protein TRF1
1997 Nature
Telomere elongation in immortal human cells without detectable telomerase activity.
1995
Telomere length predicts replicative capacity of human fibroblasts.
1992 StandoutNobel
Recombination of 4p16 DNA markers in an unusual family with Huntington disease.
1992
The long and the short of long–term memory—a molecular framework
1986 StandoutNatureNobel
G-strings at chromosome ends
1988 StandoutNatureNobel
DNA methylation: organ specific variations in the methylation pattern within and around ovalbumin and other chicken genes
1979
Nucleotide Sequence of Yellow Fever Virus: Implications for Flavivirus Gene Expression and Evolution
1985 StandoutScienceNobel
Cellular differentiation, cytidine analogs and DNA methylation
1980 Standout
Altering Genotype and Phenotype by DNA-Mediated Gene Transfer
1980 StandoutScienceNobel
Gene losses in human tumours
1988 Nature
Methylation of milk-borne and genetically transmitted mouse mammary tumor virus proviral DNA
1980
Regulated expression of telomerase activity in human T lymphocyte development and activation.
1996
Tumor Suppressor Genes: The Puzzle and the Promise
1989 Science
Cell type-specific enhancer element associated with a mouse MHC gene, Eβ
1984 StandoutNatureNobel
Correlation between Hypomethylation of DNA and Expression of Globin Genes in Friend Erythroleukemia Cells
1977
Loss of allelic heterozygosity at a second locus on chromosome 11 in sporadic Wilms' tumor cells.
1989
Mitochondrial DNA and human evolution
1987 StandoutNature
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
The future of cloning
1999 StandoutNatureNobel
5-Methylcytosine localised in mammalian constitutive heterochromatin
1974 Nature
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Tumor-specific loss of 11p15.5 alleles in del11p13 Wilms tumor and in familial adrenocortical carcinoma.
1989
Evolutionary relationships of human populations from an analysis of nuclear DNA polymorphisms
1986 Nature
Structure of catabolite gene activator protein at 2.9 Å resolution suggests binding to left-handed B-DNA
1981 StandoutNatureNobel
Lack of telomere shortening during senescence inParamecium.
1994 StandoutNobel
Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms.
1989 Standout
Molecular structure of a left-handed double helical DNA fragment at atomic resolution
1979 StandoutNature
A Human Telomeric Protein
1995 Science
Structure and variability of human chromosome ends.
1990
Expression of lymphocyte surface IgE does not require switch recombination
1982 StandoutNatureNobel
Unmethlated domains in vertebrate DNA
1983
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
1993 Standout
Sequence variation of the human Y chromosome
1995 StandoutNatureNobel
Structure and Variability of Human Chromosome Ends
1990
Structural Rearrangement of the Retinoblastoma Gene in Human Breast Carcinoma
1988 Science
Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins
1996 StandoutScienceNobel
Loss of genes on the short arm of chromosome 11 in human lung carcinomas.
1987
Drug effects on nucleic acid modification. I. A specific effect of 5-azacytidine on mammalian transfer RNA methylation invivo
1976
Dna Methylation and its Possible Biological Roles
1981
Site-Specific Cleavage of Human Chromosome 4 Mediated by Triple-Helix Formation
1991 Science
Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma Cells
1993 StandoutScienceNobel
Activation of telomerase in a human tumor.
1994
CpG-rich islands and the function of DNA methylation
1986 StandoutNature
Developmental and tissue-specific regulation of mouse telomerase and telomere length.
1995 StandoutNobel
Cloning human telomeric DNA fragments into Saccharomyces cerevisiae using a yeast-artificial-chromosome vector.
1989
CpG island clones from a deletion encompassing the gene for adenomatous polyposis coli.
1989
A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA
1985
DNA methylation and viral gene expression in adenovirus-transformed and-infected cells
1980
The RNA Component of Human Telomerase
1995 StandoutScienceNobel
Non-random association between alleles detected at D4S95 and D4S98 and the Huntington's disease gene.
1989
Telomerase activity in normal and malignant hematopoietic cells.
1995
Low incidence of loss of chromosome 10 in sporadic and hereditary human medullary thyroid carcinoma.
1989
Functional Evidence for an RNA Template in Telomerase
1990 StandoutScienceNobel
Location cloning strategy for characterizing genetic defects in Huntington's disease and Alzheimer's disease
1989
A nuclear 'fossil' of the mitochondrial D-loop and the origin of modern humans
1995 StandoutNatureNobel
Tissue-specific DNA methylation in a cluster of rabbit beta-like globin genes.
1980
Defined physical limits of the Huntington disease gene candidate region.
1991
Methylation of integrated adenovirus type 12 DNA sequences in transformed cells is inversely correlated with viral gene expression.
1980
Stringent sequence requirements for the formation of human telomeres.
1994
DNA methylase from HeLa cell nuclei
1975
Structure and function of telomeres
1991 StandoutNatureNobel
A yeast artificial chromosome telomere clone spanning a possible location of the Huntington disease gene.
1990
DNA methylation and the frequency of CpG in animal DNA
1980
Complex patterns of linkage disequilibrium in the Huntington disease region.
1991
A recombination event that redefines the Huntington disease region.
1992
Human telomeres are attached to the nuclear matrix.
1992
Telomere length constancy during aging of Saccharomyces cerevisiae
1991
DNA Methylation and Gene Function
1980 StandoutScience
Variable patterns of total DNA and rDNA methylation in animals
1980
Methylation of foreign DNA sequences in eukaryotic cells.
1980
Linkage disequilibrium in Huntington's disease: an improved localisation for the gene.
1989
Works of Barbara A. Smith being referenced
Isolation of DNA markers in the direction of the Huntington disease gene from the G8 locus.
1988
A highly polymorphic locus very tightly linked to the Huntington's disease gene
1988 Nature
Clustering of multiallele DNA markers near the Huntington's disease gene.
1989
Isolation of a novel mildly repetitive DNA sequence that is predominantly located at the terminus of the short arm of chromosome 4 near the Huntington disease gene
1989
Development of multiple endocrine neoplasia type 2A does not involve substantial deletions of chromosome 10
1989
Mapping ofD4S98/S114/S113confines the Huntington's defect to a reduced physical region at the telomere of chromosome 4
1988
A new DNA marker (D4S90) is located terminally on the short arm of chromosome 4, close to the Huntington disease gene
1989
Recombination events suggest potential sites for the Huntington's disease gene
1989
A cell hybrid and recombinant DNA library that facilitate identification of polymorphic loci in the vicinity of the Huntington disease gene.
1986
Construction of aNotI linking library and isolation of new markers close to the Huntington's disease gene
1988
A polymorphic DNA marker that represents a conserved expressed sequence in the region of the Huntington disease gene.
1988
Methylated and unmethylated DNA compartments in the sea urchin genome
1979
An estimate of unique DNA sequence heterozygosity in the human genome
1985
Biomethylation of deoxyribonucleic acid in cultured human tumour cells (HeLa). Methylated bases other than 5-methylcytosine not detected
1972
Variability at the Telomeres of the Human X/Y Pseudoautosomal Region
1986
Deletion of genes on chromosome 1 in endocrine neoplasia
1987 Nature