Standout Papers

A mouse model for beta 0-thalassemia. 1995 2026 2005 2015 215
  1. A mouse model for beta 0-thalassemia. (1995)
    Baoli Yang, Suzanne L. Kirby et al. Proceedings of the National Academy of Sciences
  2. A Common Human β Globin Splicing Mutation Modeled in Mice (1998)
    Baoli Yang, Ronald Kim et al. Blood

Citation Impact

Citing Papers

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Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
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Conformational Switch of Syntaxin-1 Controls Synaptic Vesicle Fusion
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PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex
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Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner
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ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures
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Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
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Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors
2014 StandoutNatureNobel
Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch
2006
A Nonproton Ligand Sensor in the Acid-Sensing Ion Channel
2010
Discoveries in structure and physiology of mechanically activated ion channels
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Piecing together a ciliome
2006
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
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Molecular mechanisms of nociception
2001 StandoutNatureNobel
Bardet-Biedl syndrome: an emerging pathomechanism of intracellular transport
2006
Dynamic control of neuroexocytosis by phosphoinositides in health and disease
2010
Merkel Cells Transduce and Encode Tactile Stimuli to Drive Aβ-Afferent Impulses
2014
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
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Mammalian phosphoinositide kinases and phosphatases
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Piezo2 is required for Merkel-cell mechanotransduction
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Piezo proteins are pore-forming subunits of mechanically activated channels
2012 StandoutNatureNobel
Interpreting Neonatal Lethal Phenotypes in Mouse Mutants: Insights Into Gene Function and Human Diseases
2009
Acid-Sensing Ion Channels (ASICs): Pharmacology and implication in pain
2010
A stomatin-domain protein essential for touch sensation in the mouse
2006 Nature
Docking of Secretory Vesicles Is Syntaxin Dependent
2006
Bardet–Biedl syndrome genes are important in retrograde intracellular trafficking and Kupffer's vesicle cilia function
2006
Localization of mechanosensitive channel TRPV4 in mouse skin
2003
The Ion Channel ASIC2 Is Required for Baroreceptor and Autonomic Control of the Circulation
2009
Characterization of Acid-sensing Ion Channels in Dorsal Horn Neurons of Rat Spinal Cord
2004
Visualizing the mechanical activation of Src
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Sensory Functions for Degenerin/Epithelial Sodium Channels (DEG/ENaC)
2011
Molecular basis of mechanosensory transduction
2001 Nature
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
2011 StandoutNatureNobel
The mechanosensory protein MEC-6 is a subunit of the C. elegans touch-cell degenerin channel
2002 StandoutNatureNobel
Molecular mechanisms of mechanotransduction in mammalian sensory neurons
2011
The role of the capsaicin receptor TRPV1 and acid-sensing ion channels (ASICS) in proton sensitivity of subpopulations of primary nociceptive neurons in rats and mice
2006
Cleft lip and palate
2009 Standout
Membrane protein sequestering by ionic protein–lipid interactions
2011 StandoutNatureNobel
Splanchnic and pelvic mechanosensory afferents signal different qualities of colonic stimuli in mice
2004 Standout
The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals
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Retinitis pigmentosa
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Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
Interaction of Nitric Oxide Synthase with the Postsynaptic Density Protein PSD-95 and α1-Syntrophin Mediated by PDZ Domains
1996 Standout
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
1999 StandoutNature
TRPM8 Is Required for Cold Sensation in Mice
2007 StandoutNobel
GABPβ2 Is Dispensible for Normal Lymphocyte Development but Moderately Affects B Cell Responses
2008
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Different contributions of ASIC channels 1a, 2, and 3 in gastrointestinal mechanosensory function
2005
The DRASIC Cation Channel Contributes to the Detection of Cutaneous Touch and Acid Stimuli in Mice
2001
Molecular basis of infrared detection by snakes
2010 StandoutNatureNobel
Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy
2013 Standout
Speed and Temperature Dependences of Mechanotransduction in Afferent Fibers Recorded From the Mouse Saphenous Nerve
2008
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
2002 StandoutNatureNobel
A TRP Channel that Senses Cold Stimuli and Menthol
2002 StandoutNobel
Genetic variants in IRF6 and the risk of facial clefts: single‐marker and haplotype‐based analyses in a population‐based case‐control study of facial clefts in Norway
2008
Mechanosensation and pain
2004
Mechanotransduction and chemosensitivity of two major classes of bladder afferents with endings in the vicinity to the urothelium
2009
Signals involved in thymocyte positive and negative selection
1999
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation
2002 StandoutNatureNobel
Acid-sensing ion channels: advances, questions and therapeutic opportunities
2006
Distinct ASIC currents are expressed in rat putative nociceptors and are modulated by nerve injury
2006
Stomatin‐domain protein interactions with acid‐sensing ion channels modulate nociceptor mechanosensitivity
2013
Mammalian somatosensory mechanotransduction
2009
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
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Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
The Acid-Activated Ion Channel ASIC Contributes to Synaptic Plasticity, Learning, and Memory
2002
The menthol receptor TRPM8 is the principal detector of environmental cold
2007 StandoutNatureNobel
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
A Core Complex of BBS Proteins Cooperates with the GTPase Rab8 to Promote Ciliary Membrane Biogenesis
2007 Standout
Localization of β and γ subunits of ENaC in sensory nerve endings in the rat foot pad
2000
Ciliar functions in the nephron
2009
PIEZO2 in sensory neurons and urothelial cells coordinates urination
2020 StandoutNatureNobel
The role of Drosophila Piezo in mechanical nociception
2012 StandoutNatureNobel
PH domain: the first anniversary
1994
Spider toxins activate the capsaicin receptor to produce inflammatory pain
2006 StandoutNatureNobel
Comparative Genomics and Gene Expression Analysis Identifies BBS9, a New Bardet-Biedl Syndrome Gene
2005
Acid‐sensing ion channels ASIC2 and ASIC3 do not contribute to mechanically activated currents in mammalian sensory neurones
2004
The receptor site of the spider toxin PcTx1 on the proton‐gated cation channel ASIC1a
2005
TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents
2006 StandoutNobel
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
Comparative Genomic Analysis Identifies an ADP-Ribosylation Factor–like Gene as the Cause of Bardet-Biedl Syndrome (BBS3)
2004
Quiet as a mouse: dissecting the molecular and genetic basis of hearing
2008
Neurosensory mechanotransduction
2008 StandoutNobel
TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons
2009
Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ
1996 StandoutNobel
Targeting Tetramer-Forming GABPβ Isoforms Impairs Self-Renewal of Hematopoietic and Leukemic Stem Cells
2012
Eukaryotic Mechanosensitive Channels
2010 Nobel
In vivo selection of genetically modified erythroblastic progenitors leads to long-term correction of β-thalassemia
2008
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
Interaction of Acid-sensing Ion Channel (ASIC) 1 with the Tarantula Toxin Psalmotoxin 1 is State Dependent
2006
DEG/ENaC ion channels involved in sensory transduction are modulated by cold temperature
2001
Transport and Localization of the DEG/ENaC Ion Channel BNaC1α to Peripheral Mechanosensory Terminals of Dorsal Root Ganglia Neurons
2001
MKKS/BBS6, a divergent chaperonin-like protein linked to the obesity disorder Bardet-Biedl syndrome, is a novel centrosomal component required for cytokinesis
2005
Impaired Thermosensation in Mice Lacking TRPV3, a Heat and Camphor Sensor in the Skin
2005 StandoutScienceNobel
Pharmacological Dissection and Distribution of NaN/Nav1.9, T-type Ca2+ Currents, and Mechanically Activated Cation Currents in Different Populations of DRG Neurons
2006
Heteromultimers of DEG/ENaC subunits form H + -gated channels in mouse sensory neurons
2002
Binding of Neuroligins to PSD-95
1997 StandoutScienceNobel
Distinct Mechanosensitive Properties of Capsaicin-Sensitive and -Insensitive Sensory Neurons
2002
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration
2000 StandoutScienceNobel
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Mechanotransduction: All Signals Point to Cytoskeleton, Matrix, and Integrins
2002
Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy.
1994 StandoutNobel
Genetics of Sensory Mechanotransduction
2002 StandoutNobel

Works of Baoli Yang being referenced

Bardet–Biedl syndrome type 4 (BBS4)-null mice implicate Bbs4 in flagella formation but not global cilia assembly
2004
Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice
2007
Loss of mXinα, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects
2007
The mammalian sodium channel BNC1 is required for normal touch sensation
2000 Nature
The ubiquitin ligase adaptor Ndfip1 regulates T cell-mediated gastrointestinal inflammation and inflammatory bowel disease susceptibility
2010
Syntaxin 4 heterozygous knockout mice develop muscle insulin resistance
2001
Abnormal skin, limb and craniofacial morphogenesis in mice deficient for interferon regulatory factor 6 (Irf6)
2006
Selective Cochlear Degeneration in Mice Lacking the F-Box Protein, Fbx2, a Glycoprotein-Specific Ubiquitin Ligase Subunit
2007
Mkks-null mice have a phenotype resembling Bardet–Biedl syndrome
2005
Disruption of the β subunit of the epithelial Na + channel in mice: Hyperkalemia and neonatal death associated with a pseudohypoaldosteronism phenotype
1999
Targeting the GA Binding Protein β1L Isoform Does Not Perturb Lymphocyte Development and Function
2008
Heterogeneity of the 59-kDa dystrophin-associated protein revealed by cDNA cloning and expression.
1994
Bbs2 -null mice have neurosensory deficits, a defect in social dominance, and retinopathy associated with mislocalization of rhodopsin
2004
Requirement for the Leukocyte-Specific Adapter Protein SLP-76 for Normal T Cell Development
1998 Science
A mouse model for beta 0-thalassemia.
1995 StandoutNobel
Rankless by CCL
2026