Citation Impact
Citing Papers
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
Incorporation of sensing modalities into de novo designed fluorescence-activating proteins
2021 StandoutNobel
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
De novo design of immunoglobulin-like domains
2022 StandoutNobel
Creating new fluorescent probes for cell biology
2002 StandoutNobel
HIV-1 rev regulation involves recognition of non-Watson-Crick base pairs in viral RNA
1991 StandoutNobel
Identification of a novel nuclear pore-associated protein as a functional target of the HIV-1 Rev protein in yeast
1995 StandoutNobel
Contemporary strategies for the stabilization of peptides in the α-helical conformation
2008
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Two novel series of allocolchicinoids with modified seven membered B-rings: design, synthesis, inhibition of tubulin assembly and cytotoxicity
2005
K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
2013 StandoutNature
Molecular dynamics simulations of helix denaturation
1992 StandoutNobel
Nuclear RNA export
1998 StandoutNobel
A synthetic oscillatory network of transcriptional regulators
2000 StandoutNature
Quantitative Analysis of the Complex between p21 and the Ras-binding Domain of the Human Raf-1 Protein Kinase
1995
Multi-input chemical control of protein dimerization for programming graded cellular responses
2019 StandoutNobel
Taking advantage of luminescent lanthanide ions
2005 Standout
NMR characterization of interleukin‐2 in complexes with the IL‐2Rα receptor component, and with low molecular weight compounds that inhibit the IL‐2/IL‐Rα interaction
2003
Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression
2008 Standout
Interactions between Ras proteins and their effectors
1996
Post‐Crystal Engineering of Zinc‐Substituted Myoglobin to Construct a Long‐Lived Photoinduced Charge‐Separation System
2011 StandoutNobel
Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain
2004 StandoutNature
The Nuclear Transport Factor Karyopherin β Binds Stoichiometrically to Ran-GTP and Inhibits the Ran GTPase Activating Protein
1996 StandoutNobel
Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
2014 Standout
Solid phase peptide synthesis utilizing 9‐fluorenylmethoxycarbonyl amino acids
1990 Standout
The Acidic Transcription Activator Gcn4 Binds the Mediator Subunit Gal11/Med15 Using a Simple Protein Interface Forming a Fuzzy Complex
2011 StandoutNobel
Relationship between nuclear magnetic resonance chemical shift and protein secondary structure
1991 Standout
A Membrane-proximal Basic Domain and Cysteine Cluster in the C-terminal Tail of CCR5 Constitute a Bipartite Motif Critical for Cell Surface Expression
2001 StandoutNobel
The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex
1995 StandoutNobel
HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: Implications for HIV-1 latency
1991
MIF as a glucocorticoid-induced modulator of cytokine production
1995 StandoutNature
Purification, Bioactivity, and Secondary Structure Analysis of Mouse and Human Macrophage Migration Inhibitory Factor (MIF)
1994
Protein Unfolding Pathways Explored Through Molecular Dynamics Simulations
1993 StandoutNobel
Reduced Cell Surface Expression of CCR5 in CCR5Δ32 Heterozygotes Is Mediated by Gene Dosage, Rather Than by Receptor Sequestration
2002 StandoutNobel
Interactions of colchicine with tubulin
1991
Anticancer drug design based on plant-derived natural products
1999
Disassembly of RanGTP-Karyopherin β Complex, an Intermediate in Nuclear Protein Import
1997 StandoutNobel
Acetone‐Linked Peptides: A Convergent Approach for Peptide Macrocyclization and Labeling
2015
A versatile plasmid expression vector for the production of biotinylated proteins by site-specific, enzymatic modification in Escherichia coli
1996
A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae
2000 StandoutNature
Seeding “one-dimensional crystallization” of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?
1993 Standout
The Differential Effects of the Gly-60 to Ala Mutation on the Interaction of H-Ras p21 with Different Downstream Targets
1996
Human immunodeficiency virus type 1 Rev activation can be achieved without Rev-responsive element RNA if Rev is directed to the target as a Rev/MS2 fusion protein which tethers the MS2 operator RNA
1992
Transverse relaxation-optimized NMR spectroscopy with the outer membrane protein OmpX in dihexanoyl phosphatidylcholine micelles
2001 StandoutNobel
Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed Biomolecules Synthesis
2008 Standout
A model of the molten globule state from molecular dynamics simulations.
1992 StandoutNobel
A functional interaction between Rev and yeast pre-mRNA is related to splicing complex formation.
1994 StandoutNobel
Allocolchicinoid Synthesis via Direct Arylation
2005
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering
2001 StandoutNobel
A three-hybrid system to detect RNA-protein interactions in vivo.
1996
α/β-Peptide Foldamers Targeting Intracellular Protein–Protein Interactions with Activity in Living Cells
2015
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
Human immunodeficiency virus type 1 regulator of virion expression, rev, forms nucleoprotein filaments after binding to a purine-rich "bubble" located within the rev-responsive region of viral mRNAs.
1991
Recognition and sensing of chiral biological substrates via lanthanide coordination chemistry
2002
mRNA binding protein mrnp 41 localizes to both nucleus and cytoplasm
1997 StandoutNobel
Structural analysis of the interaction between the human immunodeficiency virus Rev protein and the Rev response element.
1991
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Macrocyclic Control in Helix Mimetics
2019
Protein Design: A Hierarchic Approach
1995 Science
Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation
2007 Standout
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures
2017 StandoutNobel
Identification of discrete segments of human Raf-1 kinase critical for high affinity binding to Ha-Ras.
1994
Helical Polymers: Synthesis, Structures, and Functions
2009 Standout
The Guanine Nucleotide-Binding Switch in Three Dimensions
2001 StandoutScience
Rab3 reversibly recruits rabphilin to synaptic vesicles by a mechanism analogous to raf recruitment by ras.
1996 StandoutNobel
A Phage-Assisted Continuous Selection Approach for Deep Mutational Scanning of Protein–Protein Interactions
2019
Indium metal as a reducing agent in organic synthesis
2001
Peptide stapling techniques based on different macrocyclisation chemistries
2014
Fmoc-Based Synthesis of Peptide-αThioesters: Application to the Total Chemical Synthesis of a Glycoprotein by Native Chemical Ligation
1999 StandoutNobel
trans-dominant inhibition of human immunodeficiency virus type 1 Rev occurs through formation of inactive protein complexes
1992
α-Helix nucleation by a calcium-binding peptide loop
1999
A new strategy applied to the synthesis of an α-helical bicyclic peptide constrained by two overlapping i, i+7 side-chain bridges of novel design
1996
Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells
2001 StandoutNobel
Lanthanide Complexes in Molecular Recognition and Chirality Sensing of Biological Substrates
2002
Oligomerization and RNA binding domains of the type 1 human immunodeficiency virus Rev protein: a dual function for an arginine-rich binding motif.
1991
Spatio-temporal images of growth-factor-induced activation of Ras and Rap1
2001 Nature
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation
2009 Standout
Structural Basis of Type II Topoisomerase Inhibition by the Anticancer Drug Etoposide
2011 StandoutScience
Conserved Structures and Diversity of Functions of RNA-Binding Proteins
1994 StandoutScience
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Development of α-Helical Calpain Probes by Mimicking a Natural Protein–Protein Interaction
2012
Works of B. Wegrzynski being referenced
A fast and simplein situ method for the determination of the absolute configuration of amino acid esters using the chiroptical properties of their Eu(FOD)3 complexes
1992
Characterization of recombinant HIV-1 Tat and its interaction with TAR RNA
1992
aS,7S‐absolute configuration of natural (−)‐colchicine and allocongeners
1990
Solution structures of cyclic and dicyclic analogues of growth hormone releasing factor as determined by two‐dimensional NMR and CD spectroscopies and constrained molecular dynamics
1992
Solution structure of an analog of vasoactive intestinal peptide as determined by two-dimensional NMR and circular dichroism spectroscopies and constrained molecular dynamics
1989
Synthesis, biological activity and conformational analysis of cyclic GRF analogs
1988
A Fast and Simple in Situ Method for the Determination of the Absolute Configuration of 2-and 3-Hydroxycarboxylic Acids, Esters and Ethers Using the Chiroptical Properties of Their Eu(Fod)3Complexes. A Preliminary Report
1991
Purification and characterization of recombinant Rev protein of human immunodeficiency virus type 1.
1990
Characterization of a 78-residue fragment of c-Raf-1 that comprises a minimal binding domain for the interaction with Ras-GTP.
1994
Natural products. Antitubulin effect of congeners of N-acetylcolchinyl methyl ether: synthesis of optically active 5-acetamidodeaminocolchinyl methyl ether and of demethoxy analogues of deaminocolchinyl methyl ether
1992