Citation Impact
Citing Papers
Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells
2002 StandoutScienceNobel
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
2004 StandoutScienceNobel
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
2003 StandoutScienceNobel
Spinophilin Blocks Arrestin Actions in Vitro and in Vivo at G Protein-Coupled Receptors
2004 StandoutScienceNobel
A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair
2009 StandoutNobel
Interaction of the Grb10 Adapter Protein with the Raf1 and MEK1 Kinases
1998
MST/MLK2, a Member of the Mixed Lineage Kinase Family, Directly Phosphorylates and Activates SEK1, an Activator of c-Jun N-terminal Kinase/Stress-activated Protein Kinase
1997
Identification and Characterization of an IκB Kinase
1997
Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.
1993 Standout
New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades
2001 StandoutNobel
MAPKs: new JNK expands the group
1994
From molecular to modular cell biology
1999 StandoutNatureNobel
IKAP is a scaffold protein of the IκB kinase complex
1998 Nature
Nerve Growth Factor-mediated Activation of the Mitogen-activated Protein (MAP) Kinase Cascade Involves a Signaling Complex Containing B-Raf and HSP90
1996
Gravin, an autoantigen recognized by serum from myasthenia gravis patients, is a kinase scaffold protein
1997
Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae
1998
Signalling scaffolds and local organization of cellular behaviour
2015
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Activation of the IκBα Kinase Complex by MEKK1, a Kinase of the JNK Pathway
1997
Sex, stress and integrity: the importance of MAP kinases in yeast
1994
Contribution of the ERK5/MEK5 Pathway to Ras/Raf Signaling and Growth Control
1999
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
Intrinsic disorder in scaffold proteins: Getting more from less
2008
Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK
1998
Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gβγ complex underlies activation of the yeast pheromone response pathway
1998
The N-terminal ERK-binding Site of MEK1 Is Required for Efficient Feedback Phosphorylation by ERK2 in Vitro and ERK Activation in Vivo
1999
Activation and targeting of mitogen-activated protein kinases by G-protein-coupled receptors
2002
Budding yeast morphogenesis: signalling, cytoskeleton and cell cycle
1995
The Cold Shock Domain Protein LIN-28 Controls Developmental Timing in C. elegans and Is Regulated by the lin-4 RNA
1997 StandoutNobel
'Location, location, location': activation and targeting of MAP kinases by G protein-coupled receptors
2003
Overexpression of the G1-cyclin Gene CLN2Represses the Mating Pathway in Saccharomyces cerevisiaeat the Level of the MEKK Ste11
1997
Molecular Characterization of Ste20p, a Potential Mitogen-activated Protein or Extracellular Signal-regulated Kinase Kinase (MEK) Kinase Kinase from Saccharomyces cerevisiae
1995
MEKK1 Binds Directly to the c-Jun N-terminal Kinases/Stress-activated Protein Kinases
1997
A walk-through of the yeast mating pheromone response pathway
2004
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
Mating in Saccharomyces cerevisiae: The Role of the Pheromone Signal Transduction Pathway in the Chemotropic Response to Pheromone
1997 StandoutNobel
Transcriptional Regulation by Extracellular signals: Mechanisms and Specificity
1995
Pro-inflammatory Cytokines and Environmental Stress Cause p38 Mitogen-activated Protein Kinase Activation by Dual Phosphorylation on Tyrosine and Threonine
1995 Standout
Protein Kinase A Anchoring
1997
JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension
1998
A multivalent PDZ-domain protein assembles signalling complexes in a G-protein-coupled cascade
1997 Nature
MEX-3 Is a KH Domain Protein That Regulates Blastomere Identity in Early C. elegans Embryos
1996 StandoutNobel
Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK
1998
NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain
1997
A Conserved Docking Site in MEKs Mediates High-affinity Binding to MAP Kinases and Cooperates with a Scaffold Protein to Enhance Signal Transmission
2001
Signal transduction and growth control in yeast
1995
Mechanistic Studies of the Dual Phosphorylation of Mitogen-activated Protein Kinase
1997
Functional binding between Gβ and the LIM domain of Ste5 is required to activate the MEKK Ste11
1998
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
1994 StandoutNobel
AKAPs: from structure to function
1999
Protein kinases and phosphatases: The Yin and Yang of protein phosphorylation and signaling
1995 Standout
The MEK1 Proline-rich Insert Is Required for Efficient Activation of the Mitogen-activated Protein Kinases ERK1 and ERK2 in Mammalian Cells
1998
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
MAP kinase pathways
1999
Cloning and expression of cDNA encoding a mitogen-activated protein kinase from a phytopathogenic filamentous fungus
1997
Dynamics and organization of MAP kinase signal pathways
1995
Concentration-dependent positive and negative regulation of a MAP kinase by a MAP kinase kinase
1999
Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins
1995 StandoutNobel
KSR modulates signal propagation within the MAPK cascade.
1996
The protein kinase KSR interacts with 14-3-3 protein and Raf
1997
HTLV-I Tax Protein Binds to MEKK1 to Stimulate IκB Kinase Activity and NF-κB Activation
1998
MAP kinase pathways in yeast: For mating and more
1995
Expanding roles for β-arrestins as scaffolds and adapters in GPCR signaling and trafficking
2001 StandoutNobel
New Insights into the Control of MAP Kinase Pathways
1999
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
Signal transduction by MAP kinase cascades in budding yeast
1998
MAP Kinases with Distinct Inhibitory Functions Impart Signaling Specificity during Yeast Differentiation
1997
Nuclear Shuttling of Yeast Scaffold Ste5 Is Required for Its Recruitment to the Plasma Membrane and Activation of the Mating MAPK Cascade
1999
Molecular Cloning of Mitogen-activated Protein/ERK Kinase Kinases (MEKK) 2 and 3
1996
Cloning and characterization of a single-stranded DNA binding protein that specifically recognizes deoxycytidine stretch
1994
A novel MAP-kinase kinase from Candida albicans
1997
Cloning and Characterization of MEK6, a Novel Member of the Mitogen-activated Protein Kinase Kinase Cascade
1996
Insulin disrupts β-adrenergic signalling to protein kinase A in adipocytes
2005 StandoutNatureNobel
Nucleic Acid-Binding Properties of the Xenopus Oocyte Y Box Protein mRNP3+4
1994
Signal transduction: hanging on a scaffold
2000
Purification of a 12,020-Dalton Protein That Enhances the Activation of Mitogen-activated Protein (MAP) Kinase by MAP Kinase Kinase
1995
A walk-through of the yeast mating pheromone response pathway
2004
Signaling in the Yeast Pheromone Response Pathway: Specific and High-Affinity Interaction of the Mitogen-Activated Protein (MAP) Kinases Kss1 and Fus3 with the Upstream MAP Kinase Kinase Ste7
1996
Interactions between the Ankyrin Repeat-Containing Protein Akr1p and the Pheromone Response Pathway inSaccharomyces cerevisiae
1996
β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα
2004 StandoutNobel
Reconstitution of a yeast protein kinase cascade in vitro: activation of the yeast MEK homologue STE7 by STE11.
1994
MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase.
1995
AKR1Encodes a Candidate Effector of the Gβγ Complex in theSaccharomyces cerevisiaePheromone Response Pathway and Contributes to Control of both Cell Shape and Signal Transduction
1996 StandoutNobel
Pheromone Response in Yeast: Association of Bem1p with Proteins of the MAP Kinase Cascade and Actin
1995 Science
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
1999 StandoutNobel
Characterization of Fus3 Localization: Active Fus3 Localizes in Complexes of Varying Size and Specific Activity
1999
Osmotic Activation of the HOG MAPK Pathway via Ste11p MAPKKK: Scaffold Role of Pbs2p MAPKK
1997 Science
Identification of a Dual Specificity Kinase That Activates the Jun Kinases and p38-Mpk2
1995 Science
Genetic Analysis of Default Mating Behavior in Saccharomyces cerevisiae
1997 StandoutNobel
Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
2003 StandoutNobel
A Mammalian Scaffold Complex That Selectively Mediates MAP Kinase Activation
1998 Science
MAP Kinase Pathways in the Yeast Saccharomyces cerevisiae
1998
Defective lymphocyte chemotaxis in β-arrestin2- and GRK6-deficient mice
2002 StandoutNobel
Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions*
2001 Standout
Regulation of C. elegans Life-Span by Insulinlike Signaling in the Nervous System
2000 StandoutScienceNobel
Identification of a Motif in the Carboxyl Terminus of β-Arrestin2 Responsible for Activation of JNK3
2001 StandoutNobel
Perilipin, a major hormonally regulated adipocyte-specific phosphoprotein associated with the periphery of lipid storage droplets
1991 Standout
Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: mating and invasive growth.
1994
Signaling Through Scaffold, Anchoring, and Adaptor Proteins
1997 StandoutScience
Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module.
1994
Kinase Suppressor of Ras Forms a Multiprotein Signaling Complex and Modulates MEK Localization
1999
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Mitogen-Activated Protein Kinases: Specific Messages from Ubiquitous Messengers
1999 Standout
The role of β-arrestins in the termination and transduction of G-protein-coupled receptor signals
2002 StandoutNobel
Identification and Functional Analysis of a Developmentally Regulated Extracellular Signal-Regulated Kinase Gene in Dictyostelium discoideum
1994
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair
2001 StandoutNobel
Cell Signaling in Space and Time: Where Proteins Come Together and When They’re Apart
2009 Science
Understanding Adipocyte Differentiation
1998 Standout
MP1: A MEK Binding Partner That Enhances Enzymatic Activation of the MAP Kinase Cascade
1998 Science
A General Mechanism for Network-Dosage Compensation in Gene Circuits
2010 StandoutScienceNobel
Dynamic Localization of Fus3 Mitogen-Activated Protein Kinase Is Necessary To Evoke Appropriate Responses and Avoid Cytotoxic Effects
2010
Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor
2005 StandoutNobel
JSAP1, a Novel Jun N-Terminal Protein Kinase (JNK)-Binding Protein That Functions as a Scaffold Factor in the JNK Signaling Pathway
1999
Saccharomyces cerevisiae cells execute a default pathway to select a mate in the absence of pheromone gradients.
1995 StandoutNobel
Association of the Yeast Pheromone Response G Protein βγ Subunits with the Map Kinase Scaffold Ste5p
1995 Science
The UNC-14 protein required for axonal elongation and guidance in Caenorhabditis elegans interacts with the serine/threonine kinase UNC-51.
1997
The SH3-Domain Protein Bem1 Coordinates Mitogen-Activated Protein Kinase Cascade Activation with Cell Cycle Control in Saccharomyces cerevisiae
1996
Regulation of Myosin Phosphatase by a Specific Interaction with cGMP- Dependent Protein Kinase Iα
1999 Science
Rewiring MAP Kinase Pathways Using Alternative Scaffold Assembly Mechanisms
2003 Science
The GTP-bound form of the yeast Ran/TC4 homologue blocks nuclear protein import and appearance of poly(A)+ RNA in the cytoplasm.
1995
Identification and characterization of Saccharomyces cerevisiae EXO1 , a gene encoding an exonuclease that interacts with MSH2
1997
The proliferation of MAP kinase signaling pathways in yeast
1995
Spatiotemporal dynamics of guanosine 3′,5′-cyclic monophosphate revealed by a genetically encoded, fluorescent indicator
2001 StandoutNobel
Ste5 RING-H2 Domain: Role in Ste4-Promoted Oligomerization for Yeast Pheromone Signaling
1997 Science
SMK1, a developmentally regulated MAP kinase, is required for spore wall assembly in Saccharomyces cerevisiae.
1994
Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human
1999 Standout
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
More on target with protein phosphorylation: conferring specificity by location.
1996
Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A
1998
MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6.
1996
Pheromone Signalling in Saccharomyces cerevisiae Requires the Small GTP-Binding Protein Cdc42p and Its Activator CDC24
1995
A Cytoplasmic Inhibitor of the JNK Signal Transduction Pathway
1997 Science
The Osmoregulatory Pathway Represses Mating Pathway Activity in Saccharomyces cerevisiae: Isolation of a FUS3 Mutant That Is Insensitive to the Repression Mechanism
1996
Dimerization of Ste5, a mitogen-activated protein kinase cascade scaffold protein, is required for signal transduction
1996
The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex
2009 StandoutNobel
The Ste5p scaffold
2001
Fus2 localizes near the site of cell fusion and is required for both cell fusion and nuclear alignment during zygote formation.
1995
Mutation of RGA1, which encodes a putative GTPase-activating protein for the polarity-establishment protein Cdc42p, activates the pheromone-response pathway in the yeast Saccharomyces cerevisiae.
1995
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Signal Transduction through MAP Kinase Cascades
1998 Standout
Evidence for a role of MEK and MAPK during signal transduction by protein kinase C zeta.
1995
Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties
2000
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Ste12 and Mcm1 Regulate Cell Cycle-Dependent Transcription of FAR1
1996
De novo design of protein logic gates
2020 StandoutScienceNobel
JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation.
1994
Interaction of a Mitogen-Activated Protein Kinase Signaling Module with the Neuronal Protein JIP3
2000
ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling
2003 StandoutScienceNobel
Desensitization, internalization, and signaling functions of β-arrestins demonstrated by RNA interference
2003 StandoutNobel
Works of B Satterberg being referenced
Control of the adipsin gene in adipocyte differentiation. Identification of distinct nuclear factors binding to single- and double-stranded DNA.
1990
FUS3 phosphorylates multiple components of the mating signal transduction cascade: evidence for STE12 and FAR1.
1993
Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae
1994
fos protooncogene and the regulation of gene expression in adipocyte differentiation.
1988
Relative Dependence of Different Outputs of the Saccharomyces cerevisiae Pheromone Response Pathway on the MAP Kinase Fus3p
1999
The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5.
1994