Citation Impact
Citing Papers
Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease
2009
The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency
2008 StandoutScienceNobel
Neutrophil activation on biological surfaces. Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes.
1987
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Necroptosis and its role in inflammation
2015 StandoutNature
Mycobacterial sulfolipid shows a virulence by inhibiting cord factor induced granuloma formation and TNF-α release
2006
The history, properties, and biological effects of cachectin
1988 StandoutNobel
Multiple Organ Damage Caused by Tumor Necrosis Factor and Prevented by Prior Neutrophil Depletion
1989
Concepts of tissue injury and cell death in inflammation: a historical perspective
2013
Neurotoxicity of a prion protein fragment
1993 Nature
Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins
1994 StandoutNobel
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
1992 StandoutNature
University of California/Davis Interdepartmental Conference on Gram-Negative Septicemia
1991 StandoutNobel
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
1998 StandoutNature
Lethal effect of the anti-Fas antibody in mice
1993 StandoutNature
Signalling pathways of the TNF superfamily: a double-edged sword
2003 Standout
Immunity, Inflammation, and Cancer
2010 Standout
R‐form LPS, the master key to the activation ofTLR4/MD‐2‐positive cells
2006 StandoutNobel
Recombinant human tumor necrosis factor administered as a five-day continuous infusion in cancer patients: phase I toxicity and effects on lipid metabolism.
1988
The Fas Death Factor
1995 StandoutScience
Participation of tumor necrosis factor in the mediation of gram negative bacterial lipopolysaccharide-induced injury in rabbits.
1988
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
Tumour necrosis factor and cancer
2009
Points of control in inflammation
2002 StandoutNature
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing
1994 Nature
A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
1997 StandoutNature
The inflammatory reflex
2002 StandoutNature
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
The molecular mechanism of lymphocyte-mediated tumor cell lysis
1985
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Inhibition of Systemic Inflammation by Central Action of the Neuropeptide α-Melanocyte- Stimulating Hormone
1999
Local and Systemic Effects of Intradermal Recombinant Interferon-γ in Patients with Lepromatous Leprosy
1986 StandoutNobel
The Structure of Tumor Necrosis Factor-α at 2.6 Å Resolution
1989
Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.
1986 StandoutNobel
Control of Cachectin (Tumor Necrosis Factor) Synthesis: Mechanisms of Endotoxin Resistance
1986 StandoutScienceNobel
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene
1998 StandoutScienceNobel
Recombinant tumor necrosis factor depresses cytochrome P450-dependent microsomal drug metabolism in mice
1986
The structure of tumor necrosis factor-alpha at 2.6 A resolution. Implications for receptor binding.
1989
Constitutive synthesis of tumor necrosis factor in the thymus.
1992 StandoutNobel
Cachectin and tumour necrosis factor as two sides of the same biological coin
1986 StandoutNatureNobel
Constitutive activity of the tumor necrosis factor promoter is canceled by the 3' untranslated region in nonmacrophage cell lines; a trans-dominant factor overcomes this suppressive effect.
1992 StandoutNobel
Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression.
1986
Purification and characterization of the Fas-ligand that induces apoptosis.
1994
Recombinant human tumor necrosis factor increases mRNA levels and surface expression of HLA-A,B antigens in vascular endothelial cells and dermal fibroblasts in vitro.
1986
Species specificity of human and murine tumor necrosis factor. A comparative study of tumor necrosis factor receptors.
1986
Shock and Tissue Injury Induced by Recombinant Human Cachectin
1986 StandoutScienceNobel
Tumor necrosis factor can induce fever in rats without activating protein breakdown in muscle or lipolysis in adipose tissue.
1988
Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage
1986 Nature
Crystallization of trimeric recombinant human tumor necrosis factor (cachectin).
1988 StandoutNobel
Cachectin alters anterior pituitary hormone release by a direct action in vitro.
1989 StandoutNobel
Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin
1985 StandoutScienceNobel
Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2
1997 StandoutNobel
Independent regulation of tumor necrosis factor and lymphotoxin production by human peripheral blood lymphocytes.
1987
Cachectin: More Than a Tumor Necrosis Factor
1987 StandoutNobel
Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer.
1994 StandoutNobel
Interferons and tumor necrosis factors have similar catabolic effects on 3T3 L1 cells.
1986
CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein
1990 StandoutScience
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations
2000 StandoutScienceNobel
Cloning and expression in Escherichia coli of the cDNA for murine tumor necrosis factor.
1985
Signal Sequence Trap: a Cloning Strategy for Secreted Proteins and Type I Membrane Proteins
1993 StandoutScienceNobel
An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death
1996 StandoutScienceNobel
Normal Development of Mice Deficient in β 2 M, MCClass I Proteins, and CD8 + T Cells
1990 StandoutScienceNobel
Viruses in Human Cancers
1991 StandoutScienceNobel
Production of Lymphotoxin, a Bone-Resorbing Cytokine, by Cultured Human Myeloma Cells
1987
Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1.
1986
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
1993 StandoutScience
Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro
1985 StandoutScience
Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors
1986 Nature
Chimeric tumor necrosis factor receptors with constitutive signaling activity.
1995 StandoutNobel
Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity
1984 Nature
Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor.
1985
A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells.
1993 StandoutNobel
Tumor necrosis factor is the major monocyte product that increases complement receptor expression on mature human neutrophils
1988
Cachectin/tumor necrosis factor exerts endocrine, paracrine, and autocrine control of inflammatory responses.
1988
TUMOR NECROSIS FACTOR RECEPTOR AND Fas SIGNALING MECHANISMS
1999
PapA1 and PapA2 are acyltransferases essential for the biosynthesis of theMycobacterium tuberculosisvirulence factor Sulfolipid-1
2007 StandoutNobel
Autocrine Induction of Collagenase by Serum Amyloid A-Like and β 2 -Microglobulin-Like Proteins
1989 Science
A Macrophage Factor Inhibits Adipocyte Gene Expression: An in Vitro Model of Cachexia
1985 StandoutScienceNobel
Purification of rabbit tumor necrosis factor
1985
Recombinant 55-kDa tumor necrosis factor (TNF) receptor. Stoichiometry of binding to TNF alpha and TNF beta and inhibition of TNF activity.
1991
Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin
1984 Nature
Identity of tumour necrosis factor and the macrophage-secreted factor cachectin
1985 StandoutNatureNobel
Cytolytic T cell granules. Isolation, structural, biochemical, and functional characterization.
1984
Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts.
1985 StandoutNobel
A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor.
1989
Unraveling Function in the TNF Ligand and Receptor Families
1994 StandoutScienceNobel
Interleukin-2: Inception, Impact, and Implications
1988 StandoutScience
Differentiation of a human eosinophilic leukemia cell line (EoL-1) by a human T-cell leukemia cell line (HIL-3)-derived factor
1991
Works of B Moffat being referenced
Human lymphotoxin. Production by a lymphoblastoid cell line, purification, and initial characterization.
1984
Human tumor necrosis factor. Production, purification, and characterization.
1985
Primary structure of human lymphotoxin derived from 1788 lymphoblastoid cell line.
1985