Citation Impact
Citing Papers
The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains
1988 StandoutScience
Phosphorylation of Cell Surface Receptors: A Mechanism for Regulating Signal Transduction Pathways
1988 StandoutNobel
The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases
1993 StandoutNature
Protein kinase C and T cell activation
1990
The molecular heterogeneity of protein kinase C and its implications for cellular regulation
1988 StandoutNature
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Identification of the residues in human CD4 critical for the binding of HIV
1989 StandoutNobel
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
1990 StandoutNatureNobel
Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product
1988 StandoutNature
IκB: a Specific Inhibitor of the NF-κB Transcription Factor
1988 StandoutScienceNobel
ERK-dependent threonine phosphorylation of EGF receptor modulates receptor downregulation and signaling
2008
Mitosis-specific phosphorylation of p60c-src by p34cdc2-associated protein kinase
1989 StandoutNobel
Regulation of receptor-mediated endocytosis by phorbol esters
1991
Immunosuppressive properties of synthetic peptides derived from CD4 and HLA-DR antigens
1988 StandoutNobel
HIV infection does not require endocytosis of its receptor, CD4
1988 StandoutNobel
Chemical and biological approaches to glycoprotein synthesis
1996
Inositol trisphosphate and calcium signalling
1993 StandoutNature
Removal of phosphorylation sites from the β2-adrenergic receptor delays onset of agonist-promoted desensitization
1988 StandoutNatureNobel
G Protein-coupled Receptors
1998 StandoutNobel
Synthetic glycopeptides and glycoproteins as tools for biology
2004 StandoutNobel
An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites
1995 StandoutNobel
Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck
1989 StandoutNature
The C-terminus of the S. cerevisiae α-pheromone receptor mediates an adaptive response to pheromone
1988 StandoutNobel
Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine
1991 StandoutNature
Point mutation of an FGF receptor abolishes phosphatidylinositol turnover and Ca2+ flux but not mitogenesis
1992 Nature
Protein kinase C regulates ionic conductance in hippocampal pyramidal neurons: electrophysiological effects of phorbol esters.
1985
SH2 and SH3 Domains: Elements that Control Interactions of Cytoplasmic Signaling Proteins
1991 StandoutScience
Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor
1988 StandoutScienceNobel
Tumour-promoting phorbol esters increase basal and inhibit insulin-stimulated lipogenesis in rat adipocytes without decreasing insulin binding
1985
Hidden Markov models of biological primary sequence information.
1994 StandoutNobel
Inhibition of the apparent affinity of the epidermal growth factor receptor caused by phorbol diesters correlates with phosphorylation of threonine-654 but not other sites on the receptor
1986
Protein kinase C phosphorylates pp60src at a novel site
1985
The Immunological Synapse: A Molecular Machine Controlling T Cell Activation
1999 StandoutScience
Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
1985 StandoutNature
Cytokinetic failure and asynchronous nuclear division in BHK cells overexpressing a truncated protein-tyrosine-phosphatase.
1992 StandoutNobel
Perspectives on the Role of Protein Kinase C in Stimulus-Response Coupling<xref ref-type="fn" rid="FN4">4</xref>
1986
A Strategy for the Chemoselective Synthesis of O-Linked Glycopeptides with Native Sugar−Peptide Linkages
1997 StandoutNobel
Protein kinase C phosphorylates human platelet inositol trisphosphate 5′-phosphomonoesterase, increasing the phosphatase activity
1986
Serotonin-Mediated Endocytosis of apCAM: an Early Step of Learning-Related Synaptic Growth in Aplysia
1992 StandoutScienceNobel
Pks, a raf-related sequence in humans.
1986
Oligomerization of epidermal growth factor receptors on A431 cells studied by time-resolved fluorescence imaging microscopy. A stereochemical model for tyrosine kinase receptor activation.
1995
The identification and partial characterization of the fibroblast growth factor receptor of baby hamster kidney cells.
1985
The Role of Protein Kinase C in Transmembrane Signalling
1986
Erks: their fifteen minutes has arrived.
1992
Platelet-derived growth factor mimics phorbol diester action on epidermal growth factor receptor phosphorylation at threonine-654.
1985
The Protein Kinase Complement of the Human Genome
2002 StandoutScience
Regulation of transmembrane signaling by receptor phosphorylation
1987 StandoutNobel
Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanisms
1986
Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C
1992 StandoutScience
Suppression of protein tyrosine kinase activity of the epidermal growth factor receptor by epidermal growth factor.
1986
Autophosphorylation and protein kinase C phosphorylation of the epidermal growth factor receptor. Effect on tyrosine kinase activity and ligand binding affinity.
1985
Phosphorylation of the EGF receptor from A431 epidermoid carcinoma cells by three distinct types of protein kinase C
1987
Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane
1984 Nature
Epidermal growth factor stimulates the production of phosphatidylinositol monophosphate and the breakdown of polyphosphoinositides in A431 cells.
1987
Norepinephrine and epidermal growth factor: Dynamics of their interaction in the stimulation of hepatocyte DNA synthesis
1985
Phorbol ester causes desensitization of gonadotropin-responsive adenylate cyclase in a murine Leydig tumor cell line.
1985
An early decrease in phosphatidylinositol turnover occurs on induction of friend cell differentiation and precedes the decrease in c-myc expression
1985
β-Adrenergic Receptor Kinase-2 and β-Arrestin-2 as Mediators of Odorant-Induced Desensitization
1993 StandoutScienceNobel
Functions of Ceramide in Coordinating Cellular Responses to Stress
1996 StandoutScience
Regulation of the epidermal growth factor receptor by phosphorylation
1985
Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor
1986
Identification of lymphocyte integral membrane proteins as substrates for protein kinase C. Phosphorylation of the interleukin-2 receptor, class I HLA antigens, and T200 glycoprotein.
1986
Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family.
1992 StandoutNobel
Dual actions of phorbol esters on cytosolic free Ca2+ concentrations and reconstitution with ionomycin of acute thyrotropin-releasing hormone responses.
1985
Activation of protein kinase C induces rapid internalization and subsequent degradation of muscarinic acetylcholine receptors in neuroblastoma cells.
1986
Enzymatic Glycoprotein Synthesis: Preparation of Ribonuclease Glycoforms via Enzymatic Glycopeptide Condensation and Glycosylation
1997
Synthesis of Glycoproteins
2002
Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product
1991 StandoutScience
Liver Regeneration
1997 StandoutScience
Studies and Perspectives of Protein Kinase C
1986 StandoutScience
Angiogenic Factors
1987 StandoutScience
Self-phosphorylation of epidermal growth factor receptor: evidence for a model of intermolecular allosteric activation
1987
The neu oncogene encodes an epidermal growth factor receptor-related protein
1986 Nature
Regulation of casein kinase II activity by epidermal growth factor in human A-431 carcinoma cells
1989
Activators of protein kinase C down-regulate and phosphorylate the T3/T-cell antigen receptor complex of human T lymphocytes.
1985
Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia
1998 StandoutNobel
Growth factors: The epidermal growth factor receptor gene and its product
1984 Nature
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer
1997 StandoutScience
The role of the L3T4 molecule in mitogen and antigen-activated signal transduction
1987
Identification of serine 24 as the unique site on the transferrin receptor phosphorylated by protein kinase C.
1986
Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with neu Oncogene
1985 StandoutScience
Fmoc-Based Synthesis of Peptide-αThioesters: Application to the Total Chemical Synthesis of a Glycoprotein by Native Chemical Ligation
1999 StandoutNobel
Cloning, Sequencing, and Expression of the Gene Coding for the Human Platelet α 2 -Adrenergic Receptor
1987 StandoutScienceNobel
A thousand and one protein kinases
1987
Tumor promoter enhances mitogenesis by PDGF with little effect on PDGF binding
1986 StandoutNobel
A Cell Culture Model for T Lymphocyte Clonal Anergy
1990 StandoutScience
Activation of MAP kinases by calcium-dependent and calcium-independent pathways. Stimulation by thapsigargin and epidermal growth factor.
1992
Phorbol ester and 1-oleoyl-2-acetylglycerol inhibit angiotensin activation of phospholipase C in cultured vascular smooth muscle cells.
1985
A beta-adrenergic receptor kinase-like enzyme is involved in olfactory signal termination.
1993 StandoutNobel
Structural requirements for diacylglycerols to mimic tumor-promoting phobol diester action on the epidermal growth factor receptor.
1985
Phosphorylation of the glucose transporter in vitro and in vivo by protein kinase C
1985 Nature
Role of the Cyclic AMP—Dependent Protein Kinase in Signal Transduction
1989 StandoutNobel
EGF-stimulated tyrosine phosphorylation of p185neu: a potential model for receptor interactions.
1988
Effects of protein kinase C activation after epidermal growth factor binding on epidermal growth factor receptor phosphorylation.
1986
Regulation of the epidermal growth factor receptor phosphorylation state by sphingosine in A431 human epidermoid carcinoma cells.
1988
Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylation.
1985
Dissociation of protein kinase C activation from phorbol ester-induced maturation of HL-60 leukemia cells.
1985
Phorbol esters induce transient internalization without degradation of unoccupied epidermal growth factor receptors.
1985
Protein kinase C and calcium ion in mitogenic response of macrophage-depleted human peripheral lymphocytes.
1985
Tumor-promoting phorbol diesters cause the phosphorylation of epidermal growth factor receptors in normal human fibroblasts at threonine-654.
1985
Works of B Friedman being referenced
Thapsigargin, a novel promoter, phosphorylates the epidermal growth factor receptor at threonine 669
1988
S6.2 Development of a recombinant form of Ceredase� (Glucocerebrosidase) for the treatment of Gaucher's disease
1993
Phosphorylation at threonine-654 is not required for negative regulation of the epidermal growth factor receptor by non-phorbol tumor promoters.
1989
Diacylglycerol modulates binding and phosphorylation of the epidermal growth factor receptor.
1984
Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor.
1984